3D Lung Models for Regenerating Lung Tissue is a comprehensive summary on the current state of art 3D lung models and novel techniques that can be used to regenerate lung tissue. Written by experts in the field, readers can expect to learn more about 3D lung models, novel techniques including bioprinting and advanced imaging techniques, as well as important knowledge about the complexity of the lung and its extracellular matrix composition.
Structured into 15 different chapters, the book spans from the original 2D cell culture model on plastic, to advanced 3D lung models such as using human extracellular matrix protein. In addition, the last chapters cover new techniques including 3D printing, bioprinting, and artificial intelligence that can be used to drive the field forward and some future perspectives. This highly topical book with chapters on everything from the complexity of the lung and its microenvironment to cutting-edge 3D lung models, represents an exciting body of work that can be used by researchers during study design, grant writing, as teaching material, or to stay updated with the progression of the field.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. ix 7. Preface - p. xiii 8. Chapter 1. Is the lung a complex organ to rebuild? - p. 1 9. Part I: 2D culture and the microenvironment - p. 14 10. Chapter 2. Two-dimensional cell culturing on glass and plastic: the past, the present, and the future - p. 21 11. Chapter 3. The importance of lung microenvironment - p. 37 12. Part II: 3D lung models - p. 46 13. Chapter 4. The air–liquid interface model - p. 51 14. Chapter 5. Lung organoid models - p. 73 15. Chapter 6. Biomaterials for in vitro models in lung research - p. 91 16. Chapter 7. Three dimensional lung models - Three dimensional extracellular matrix models - p. 109 17. Chapter 8. Lung-on-chip - p. 133 18. Chapter 9. Mechanical stimuli in lung regeneration - p. 153 19. Part III: New directions - p. 165 20. Chapter 10. Advanced manufacturing: three-dimensional printing and bioprinting of models of lung and airways - p. 171 21. Chapter 11. Drug screening and high throughput in three-dimensional lung models - p. 197 22. Chapter 12. Model visualization: from micro to macro - p. 207 23. Chapter 13. Artificial intelligence and computational modeling - p. 223 24. Part IV: Concluding remarks and future directions - p. 233 25. Chapter 14. Challenges and opportunities for regenerating lung tissue using three-dimensional lung models - p. 239 26. Index - p. 243
3D Lung Models for Regenerating Lung Tissue is a comprehensive summary on the current state of art 3D lung models and novel techniques that can be used to regenerate lung tissue. Written by experts in the field, readers can expect to learn more about 3D lung models, novel techniques including bioprinting and advanced imaging techniques, as well as important knowledge about the complexity of the lung and its extracellular matrix composition.
Structured into 15 different chapters, the book spans from the original 2D cell culture model on plastic, to advanced 3D lung models such as using human extracellular matrix protein. In addition, the last chapters cover new techniques including 3D printing, bioprinting, and artificial intelligence that can be used to drive the field forward and some future perspectives. This highly topical book with chapters on everything from the complexity of the lung and its microenvironment to cutting-edge 3D lung models, represents an exciting body of work that can be used by researchers during study design, grant writing, as teaching material, or to stay updated with the progression of the field.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. ix 7. Preface - p. xiii 8. Chapter 1. Is the lung a complex organ to rebuild? - p. 1 9. Part I: 2D culture and the microenvironment - p. 14 10. Chapter 2. Two-dimensional cell culturing on glass and plastic: the past, the present, and the future - p. 21 11. Chapter 3. The importance of lung microenvironment - p. 37 12. Part II: 3D lung models - p. 46 13. Chapter 4. The air–liquid interface model - p. 51 14. Chapter 5. Lung organoid models - p. 73 15. Chapter 6. Biomaterials for in vitro models in lung research - p. 91 16. Chapter 7. Three dimensional lung models - Three dimensional extracellular matrix models - p. 109 17. Chapter 8. Lung-on-chip - p. 133 18. Chapter 9. Mechanical stimuli in lung regeneration - p. 153 19. Part III: New directions - p. 165 20. Chapter 10. Advanced manufacturing: three-dimensional printing and bioprinting of models of lung and airways - p. 171 21. Chapter 11. Drug screening and high throughput in three-dimensional lung models - p. 197 22. Chapter 12. Model visualization: from micro to macro - p. 207 23. Chapter 13. Artificial intelligence and computational modeling - p. 223 24. Part IV: Concluding remarks and future directions - p. 233 25. Chapter 14. Challenges and opportunities for regenerating lung tissue using three-dimensional lung models - p. 239 26. Index - p. 243
