5-Membered Heterocycle Synthesis Using Iodine presents both old and new methods for the synthesis of various five-membered heterocycles using iodine, providing information for making specific compounds using particular reagents. Heterocyclic frameworks represent the main structural subunits of many biologically active compounds and natural products, and the ability of heterocycles to act both as reactive pharmacophores and biomimetics has greatly contributed to their unique value as traditional key elements of various drugs. Contemporary developments in process chemistry and discovery emphasize novel sustainable synthetic pathways as fast and ecologically acceptable alternatives to the traditional protocols.
This book serves as a guide for students, pharmacologists, biochemists, organic and medicinal chemists, researchers, and academic professionals to obtain easy access to synthetic protocols for different five-membered heterocycles using iodine.
1. 5-Membered Heterocycle Synthesis Using Iodine - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Biography - p. Page iv 7. Preface - p. Page v 8. List of abbreviations - p. Page vi 9. List of Illustrations - p. Page x 10. 1 : Five-membered N-heterocycles–Part I - p. Page x 11. 2 : Five-membered N-heterocycles—Part II - p. Page 29 12. 3 : Five-membered N-heterocycles: cyclization of alkenyl systems - p. Page 52 13. 4 : Five-membered N-heterocycles: cyclization of alkynyl systems - p. Page 81 14. 5 : Five-membered N,N-heterocycles - p. Page 105 15. 6 : Five-membered N,N,N- and N,N,N,N-heterocycles - p. Page 142 16. 7 : Five-membered O-heterocycles: cyclization of C=C with OH—Part I - p. Page 159 17. 8 : Five-membered O-heterocycles: cyclization of CC with OH—Part II - p. Page 199 18. 9 : Five-membered O-heterocycles: cyclization of alkenyl or alkynyl compounds - p. Page 228 19. 10 : Five-membered O- and O,O-heterocycles - p. Page 261 20. 11 : Five-membered O,N-heterocycles - p. Page 305 21. 12 : Five-membered O,N,N-heterocycles: hydrazine derivatives - p. Page 355 22. 13 : Five-membered S-heterocycles - p. Page 392 23. 14 : Five-membered S,N-heterocycles - p. Page 426 24. Index - p. Page 465
5-Membered Heterocycle Synthesis Using Iodine presents both old and new methods for the synthesis of various five-membered heterocycles using iodine, providing information for making specific compounds using particular reagents. Heterocyclic frameworks represent the main structural subunits of many biologically active compounds and natural products, and the ability of heterocycles to act both as reactive pharmacophores and biomimetics has greatly contributed to their unique value as traditional key elements of various drugs. Contemporary developments in process chemistry and discovery emphasize novel sustainable synthetic pathways as fast and ecologically acceptable alternatives to the traditional protocols.
This book serves as a guide for students, pharmacologists, biochemists, organic and medicinal chemists, researchers, and academic professionals to obtain easy access to synthetic protocols for different five-membered heterocycles using iodine.
1. 5-Membered Heterocycle Synthesis Using Iodine - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Biography - p. Page iv 7. Preface - p. Page v 8. List of abbreviations - p. Page vi 9. List of Illustrations - p. Page x 10. 1 : Five-membered N-heterocycles–Part I - p. Page x 11. 2 : Five-membered N-heterocycles—Part II - p. Page 29 12. 3 : Five-membered N-heterocycles: cyclization of alkenyl systems - p. Page 52 13. 4 : Five-membered N-heterocycles: cyclization of alkynyl systems - p. Page 81 14. 5 : Five-membered N,N-heterocycles - p. Page 105 15. 6 : Five-membered N,N,N- and N,N,N,N-heterocycles - p. Page 142 16. 7 : Five-membered O-heterocycles: cyclization of C=C with OH—Part I - p. Page 159 17. 8 : Five-membered O-heterocycles: cyclization of CC with OH—Part II - p. Page 199 18. 9 : Five-membered O-heterocycles: cyclization of alkenyl or alkynyl compounds - p. Page 228 19. 10 : Five-membered O- and O,O-heterocycles - p. Page 261 20. 11 : Five-membered O,N-heterocycles - p. Page 305 21. 12 : Five-membered O,N,N-heterocycles: hydrazine derivatives - p. Page 355 22. 13 : Five-membered S-heterocycles - p. Page 392 23. 14 : Five-membered S,N-heterocycles - p. Page 426 24. Index - p. Page 465
