Advanced Drug Delivery Systems for Colonic Disorders present the current state of the art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency.
Chapters are written in a way that allows the audience to not only become familiar with the most recent advancement in the field, but to better understand them by referring to various illustrations, figures, and informative tables. The contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the current status of clinical trials in the area.
Advanced Drug Delivery Systems for Colonic Disorders is the perfect resources for researchers in pharma, biomaterials, and nutrition to familiarize themselves with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications.
1. Chapter 1 : Introduction to colonic disorders - p. Page ix 2. Chapter 2 : Cellular and molecular mechanisms involved in colonic disorders - p. Page 18 3. Chapter 3 : Current approaches for treatment of colonic disorder - p. Page 32 4. Chapter 4 : Polysaccharides based drug delivery systems for the treatment of colon diseases - p. Page 59 5. Chapter 5 : Synthetic polymers as biomaterials for the treatment of colon diseases - p. Page 90 6. Chapter 6 : Mucoadhesive polymers as biomaterials for the treatment of colon disorders - p. Page 120 7. Chapter 7 : Colon-responsive oral drug delivery for combating colonic disorders - p. Page 147 8. Chapter 8 : Colon-responsive targeted drug delivery for treating colonic disorder - p. Page 167 9. Chapter 9 : Advancement in targeted drug delivery systems in managing colonic disorders - p. Page 199 10. Chapter 10 : Nutraceuticals and phytoceuticals in the treatment of colon disorders - p. Page 219 11. Chapter 11 : Role of prebiotics, probiotics, and synbiotics in the management of colonic disorders - p. Page 233 12. Chapter 12 : Era of biotics in managing colonic disorders - p. Page 262 13. Chapter 13 : Innovations in liposomal drug delivery: paving the way for personalized cancer therapy - p. Page 281 14. Chapter 14 : Nanoparticulate drug delivery systems for colonic disorders - p. Page 306 15. Chapter 15 : 3D printing-assisted colon-targeted drug delivery systems - p. Page 334 16. Chapter 16 : Radiopharmaceutical-based approaches for the determination of colon-targeting efficiency - p. Page 361 17. Chapter 17 : Colonic disorder management: challenges and prospects - p. Page 379 18. Chapter 18 : Clinical trials and regulatory aspects of drug delivery system for colonic disorders - p. Page 399 19. Index - p. Page 423
Advanced Drug Delivery Systems for Colonic Disorders present the current state of the art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency.
Chapters are written in a way that allows the audience to not only become familiar with the most recent advancement in the field, but to better understand them by referring to various illustrations, figures, and informative tables. The contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the current status of clinical trials in the area.
Advanced Drug Delivery Systems for Colonic Disorders is the perfect resources for researchers in pharma, biomaterials, and nutrition to familiarize themselves with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications.
1. Chapter 1 : Introduction to colonic disorders - p. Page ix 2. Chapter 2 : Cellular and molecular mechanisms involved in colonic disorders - p. Page 18 3. Chapter 3 : Current approaches for treatment of colonic disorder - p. Page 32 4. Chapter 4 : Polysaccharides based drug delivery systems for the treatment of colon diseases - p. Page 59 5. Chapter 5 : Synthetic polymers as biomaterials for the treatment of colon diseases - p. Page 90 6. Chapter 6 : Mucoadhesive polymers as biomaterials for the treatment of colon disorders - p. Page 120 7. Chapter 7 : Colon-responsive oral drug delivery for combating colonic disorders - p. Page 147 8. Chapter 8 : Colon-responsive targeted drug delivery for treating colonic disorder - p. Page 167 9. Chapter 9 : Advancement in targeted drug delivery systems in managing colonic disorders - p. Page 199 10. Chapter 10 : Nutraceuticals and phytoceuticals in the treatment of colon disorders - p. Page 219 11. Chapter 11 : Role of prebiotics, probiotics, and synbiotics in the management of colonic disorders - p. Page 233 12. Chapter 12 : Era of biotics in managing colonic disorders - p. Page 262 13. Chapter 13 : Innovations in liposomal drug delivery: paving the way for personalized cancer therapy - p. Page 281 14. Chapter 14 : Nanoparticulate drug delivery systems for colonic disorders - p. Page 306 15. Chapter 15 : 3D printing-assisted colon-targeted drug delivery systems - p. Page 334 16. Chapter 16 : Radiopharmaceutical-based approaches for the determination of colon-targeting efficiency - p. Page 361 17. Chapter 17 : Colonic disorder management: challenges and prospects - p. Page 379 18. Chapter 18 : Clinical trials and regulatory aspects of drug delivery system for colonic disorders - p. Page 399 19. Index - p. Page 423
