Advancements in Modeling-Based Therapeutics and Technology for Chronic Diseases delves into the crucial role of animal and cellular models in comprehending the intricate mechanisms of chronic diseases. The book emphasizes the importance of these models in predicting disease progression, testing new therapeutic approaches, and understanding how environmental and genetic factors interplay in the development of long-term health conditions. With a multidisciplinary approach, it bridges the gap between experimental research and clinical applications, offering insights into not only disease management but also the future of personalized medicine.
The book also sheds light on emerging technologies, including bioinformatics tools and in silico modeling, which further enhance our ability to tackle chronic diseases. It explores how these advancements are transforming research methodologies and providing novel solutions for diagnosis and treatment. Additionally, it highlights collaborative strategies between researchers, clinicians, and technologists, stressing the importance of integrated efforts in addressing global health challenges effectively.
1. Cover image - p. c 2. Title page - p. i 3. Copyright - p. iv 4. Contents - p. v 5. Contributors - p. xxi 6. Preface - p. xxvii 7. Section 1 Chronic diseases, modeling, and therapeutic strategies - p. 1 8. Chapter 1 Unraveling the complexity of chronic diseases: an introductory exploration - p. 3 9. Chapter 2 Comparative information of different animal models used in chronic diseases - p. 51 10. Chapter 3 Precision medicine: Tailoring therapeutics through advanced modeling strategies - p. 85 11. Chapter 4 Personalized drug design: From models to therapeutics - p. 109 12. Chapter 5 Advancements in biomarker discovery and validation for targeted therapies - p. 135 13. Chapter 6 Advancement in the animal model-based therapeutics in neurodegenerative diseases - p. 165 14. Chapter 7 Cellular models of chronic diseases: From bench to bedside - p. 201 15. Chapter 8 Toxin-induced animal models in Parkinson's disease: Recent updates - p. 227 16. Chapter 9 Immunotherapy modeling: Harnessing the immune system in chronic disease treatment - p. 253 17. Chapter 10 The role of transnational models for the management of chronic diseases - p. 283 18. Section 2 Technological innovations in chronic disease management - p. 305 19. Chapter 11 Gene editing technologies: Transformative approaches to chronic disease treatment - p. 307 20. Chapter 12 Innovations in imaging technologies for disease modeling and monitoring - p. 333 21. Chapter 13 Computational tools and techniques for disease modeling: Bridging the gap - p. 373 22. Chapter 14 Integrated systems biology approaches in chronic disease research - p. 419 23. Section 3 Ethical and regulatory considerations - p. 445 24. Chapter 15 Ethical considerations in transnational chronic disease management models - p. 447 25. Chapter 16 Exploring ethical dilemmas and regulatory obstacles in modeling-based therapeutics: Addressing data privacy concerns - p. 463 26. Index - p. 475
Advancements in Modeling-Based Therapeutics and Technology for Chronic Diseases delves into the crucial role of animal and cellular models in comprehending the intricate mechanisms of chronic diseases. The book emphasizes the importance of these models in predicting disease progression, testing new therapeutic approaches, and understanding how environmental and genetic factors interplay in the development of long-term health conditions. With a multidisciplinary approach, it bridges the gap between experimental research and clinical applications, offering insights into not only disease management but also the future of personalized medicine.
The book also sheds light on emerging technologies, including bioinformatics tools and in silico modeling, which further enhance our ability to tackle chronic diseases. It explores how these advancements are transforming research methodologies and providing novel solutions for diagnosis and treatment. Additionally, it highlights collaborative strategies between researchers, clinicians, and technologists, stressing the importance of integrated efforts in addressing global health challenges effectively.
1. Cover image - p. c 2. Title page - p. i 3. Copyright - p. iv 4. Contents - p. v 5. Contributors - p. xxi 6. Preface - p. xxvii 7. Section 1 Chronic diseases, modeling, and therapeutic strategies - p. 1 8. Chapter 1 Unraveling the complexity of chronic diseases: an introductory exploration - p. 3 9. Chapter 2 Comparative information of different animal models used in chronic diseases - p. 51 10. Chapter 3 Precision medicine: Tailoring therapeutics through advanced modeling strategies - p. 85 11. Chapter 4 Personalized drug design: From models to therapeutics - p. 109 12. Chapter 5 Advancements in biomarker discovery and validation for targeted therapies - p. 135 13. Chapter 6 Advancement in the animal model-based therapeutics in neurodegenerative diseases - p. 165 14. Chapter 7 Cellular models of chronic diseases: From bench to bedside - p. 201 15. Chapter 8 Toxin-induced animal models in Parkinson's disease: Recent updates - p. 227 16. Chapter 9 Immunotherapy modeling: Harnessing the immune system in chronic disease treatment - p. 253 17. Chapter 10 The role of transnational models for the management of chronic diseases - p. 283 18. Section 2 Technological innovations in chronic disease management - p. 305 19. Chapter 11 Gene editing technologies: Transformative approaches to chronic disease treatment - p. 307 20. Chapter 12 Innovations in imaging technologies for disease modeling and monitoring - p. 333 21. Chapter 13 Computational tools and techniques for disease modeling: Bridging the gap - p. 373 22. Chapter 14 Integrated systems biology approaches in chronic disease research - p. 419 23. Section 3 Ethical and regulatory considerations - p. 445 24. Chapter 15 Ethical considerations in transnational chronic disease management models - p. 447 25. Chapter 16 Exploring ethical dilemmas and regulatory obstacles in modeling-based therapeutics: Addressing data privacy concerns - p. 463 26. Index - p. 475
