Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment is an authoritative guide that delves into the foundational principles, recent advancements, and clinical applications of this innovative treatment approach, aiming to bridge the gap between research and clinical practice. It offers a thorough analysis of the mechanisms of action, therapeutic efficacy, and safety profiles of various cellular immunotherapy modalities, enabling clinicians to make well-informed treatment decisions and optimize patient outcomes. The book promotes interdisciplinary collaboration by bringing together experts from oncology, immunology, molecular biology, and translational medicine. Through detailed case studies, clinical guidelines, and practical insights, it provides healthcare professionals with the knowledge and tools needed to effectively incorporate cellular immunotherapy into standard oncology practice. Additionally, the book addresses key challenges and future directions in the field, such as strategies to enhance treatment efficacy, overcome resistance mechanisms, and broaden the accessibility of cellular immunotherapy to more patients. Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment aims to educate and empower healthcare professionals, fostering continued innovation and collaboration to improve cancer care and patient outcomes.
1. Chapter 1 Introduction to personalized cellular immunotherapy - p. 1 2. Chapter 2 Understanding the therapeutic significance of tumor-infiltrating immune cells and their characteristics: A historical overview of cancer immunotherapy - p. 35 3. Chapter 3 A groundbreaking development in cancer treatment: Chimeric antigen receptor (CAR) T-cell therapy - p. 63 4. Chapter 4 Recent progress in CAR-T cell therapy for B-cell cancers with resistant tissues - p. 89 5. Chapter 5 Targeting the tumor vasculature using mesenchymal stem cells in cancer therapy: New perspectives - p. 115 6. Chapter 6 Mesenchymal stromal cell-based delivery of oncolytic viruses: A novel strategy for immunotherapy of metastatic tumors - p. 133 7. Chapter 7 Cancer treatment advancements in the era of immune checkpoint inhibitors via cellular immunotherapies - p. 173 8. Chapter 8 The future of cancer immunotherapy: Combining gene and cellular approaches - p. 187 9. Chapter 9 Platelet shielding of cancer cells: Implications for immunotherapy strategies - p. 211 10. Chapter 10 Cancer cell-platelet interactions: Harnessing therapeutic opportunities in cancer treatment - p. 241 11. Chapter 11 Myeloid-derived suppressor cells: A promising target for anticancer immunotherapy - p. 271 12. Chapter 12 Utilizing nanomedicines to modulate myeloid-derived suppressor cells: Enhancing cancer immunotherapy - p. 297 13. Chapter 13 Unlocking the potential of macrophages: Advancements in cellular immunotherapy - p. 319 14. Chapter 14 Combination therapy: A new strategy to manage cancer - p. 351 15. Chapter 15 Future perspective of cellular immunotherapy in cancer treatment - p. 389 16. Index - p. 407
Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment is an authoritative guide that delves into the foundational principles, recent advancements, and clinical applications of this innovative treatment approach, aiming to bridge the gap between research and clinical practice. It offers a thorough analysis of the mechanisms of action, therapeutic efficacy, and safety profiles of various cellular immunotherapy modalities, enabling clinicians to make well-informed treatment decisions and optimize patient outcomes. The book promotes interdisciplinary collaboration by bringing together experts from oncology, immunology, molecular biology, and translational medicine. Through detailed case studies, clinical guidelines, and practical insights, it provides healthcare professionals with the knowledge and tools needed to effectively incorporate cellular immunotherapy into standard oncology practice. Additionally, the book addresses key challenges and future directions in the field, such as strategies to enhance treatment efficacy, overcome resistance mechanisms, and broaden the accessibility of cellular immunotherapy to more patients. Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment aims to educate and empower healthcare professionals, fostering continued innovation and collaboration to improve cancer care and patient outcomes.
1. Chapter 1 Introduction to personalized cellular immunotherapy - p. 1 2. Chapter 2 Understanding the therapeutic significance of tumor-infiltrating immune cells and their characteristics: A historical overview of cancer immunotherapy - p. 35 3. Chapter 3 A groundbreaking development in cancer treatment: Chimeric antigen receptor (CAR) T-cell therapy - p. 63 4. Chapter 4 Recent progress in CAR-T cell therapy for B-cell cancers with resistant tissues - p. 89 5. Chapter 5 Targeting the tumor vasculature using mesenchymal stem cells in cancer therapy: New perspectives - p. 115 6. Chapter 6 Mesenchymal stromal cell-based delivery of oncolytic viruses: A novel strategy for immunotherapy of metastatic tumors - p. 133 7. Chapter 7 Cancer treatment advancements in the era of immune checkpoint inhibitors via cellular immunotherapies - p. 173 8. Chapter 8 The future of cancer immunotherapy: Combining gene and cellular approaches - p. 187 9. Chapter 9 Platelet shielding of cancer cells: Implications for immunotherapy strategies - p. 211 10. Chapter 10 Cancer cell-platelet interactions: Harnessing therapeutic opportunities in cancer treatment - p. 241 11. Chapter 11 Myeloid-derived suppressor cells: A promising target for anticancer immunotherapy - p. 271 12. Chapter 12 Utilizing nanomedicines to modulate myeloid-derived suppressor cells: Enhancing cancer immunotherapy - p. 297 13. Chapter 13 Unlocking the potential of macrophages: Advancements in cellular immunotherapy - p. 319 14. Chapter 14 Combination therapy: A new strategy to manage cancer - p. 351 15. Chapter 15 Future perspective of cellular immunotherapy in cancer treatment - p. 389 16. Index - p. 407