Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including liposome-based chemotherapy and immunotherapy, human polyomaviruses, the role of micro RNAs in CLL, and cancer and cholesterol.
1. I. Introduction 2. II. Biology of Polyomaviruses 3. III. Merkel Cell Polyomavirus and Human Cancer 4. IV. SV40 as a Classic Model System 5. V. Conclusion 6. Acknowledgments 7. The Tyrosine Phosphatase Shp2 in Development and Cancer 8. I. Introduction 9. II. Shp2 Activation and Signaling 10. III. Lessons from Human and Murine Gain-of-Function Mutations of Shp2 11. IV. Lessons from Loss-of-Function Mutations of Shp2 12. V. Organ Specific Roles of Shp2: Lessons from Mutations in Mice 13. VI. Conclusions and Perspectives 14. CXC Chemokines in Cancer Angiogenesis and Metastases 15. I. Introduction 16. II. Angiogenic CXC Chemokines and Receptors 17. III. Angiostatic CXC Chemokines and Receptors 18. IV. Immunoangiostasis 19. V. Chemokine-Induced Angiogenesis in Tumor Models 20. VI. Chemokines Affect on Cancer Metastases 21. VII. Conclusion 22. Genetically Engineered Mouse Models in Cancer Research 23. I. Introduction 24. II. Generation of Genetically Engineered Mouse Models 25. III. Cancer Paradigms and Lessons from the Mouse 26. IV. Summary 27. Acknowledgments
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including liposome-based chemotherapy and immunotherapy, human polyomaviruses, the role of micro RNAs in CLL, and cancer and cholesterol.
1. I. Introduction 2. II. Biology of Polyomaviruses 3. III. Merkel Cell Polyomavirus and Human Cancer 4. IV. SV40 as a Classic Model System 5. V. Conclusion 6. Acknowledgments 7. The Tyrosine Phosphatase Shp2 in Development and Cancer 8. I. Introduction 9. II. Shp2 Activation and Signaling 10. III. Lessons from Human and Murine Gain-of-Function Mutations of Shp2 11. IV. Lessons from Loss-of-Function Mutations of Shp2 12. V. Organ Specific Roles of Shp2: Lessons from Mutations in Mice 13. VI. Conclusions and Perspectives 14. CXC Chemokines in Cancer Angiogenesis and Metastases 15. I. Introduction 16. II. Angiogenic CXC Chemokines and Receptors 17. III. Angiostatic CXC Chemokines and Receptors 18. IV. Immunoangiostasis 19. V. Chemokine-Induced Angiogenesis in Tumor Models 20. VI. Chemokines Affect on Cancer Metastases 21. VII. Conclusion 22. Genetically Engineered Mouse Models in Cancer Research 23. I. Introduction 24. II. Generation of Genetically Engineered Mouse Models 25. III. Cancer Paradigms and Lessons from the Mouse 26. IV. Summary 27. Acknowledgments
