This premier volume of Advances in Oncology highlights the latest findings and updates within the cancer field each year for the practicing oncologist. Advances in Oncology publishes the most current thinking and recent advances from the voice of a truly distinguished editorial board, including Editor-in-Chief Leonidas C. Platanias, who identify current advances and breakthroughs in the field and invite specialists to contribute original articles on these topics. Topics discussed in this first volume are within the areas of radiation oncology, surgical oncology, medical oncology, gynecologic oncology, pediatric oncology, neuro-oncology, hemato-oncology, uro-oncology, and gastrointestinal oncology. This volume will appeal to all practicing oncologists and will inform and enhance clinical practice.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Editorial Board - p. iii 6. Contributors - p. v 7. Preface - p. xix 8. Section I: Radiation Oncology - p. xix 9. Radiation-Induced Cardiotoxicity: From Bench to Bedside and Beyond - p. 1 10. Radiotherapy for Metastatic Non–Small Cell Lung Cancer: An Emerging Tool for Systemic Control - p. 15 11. MRI-Guided Radiation Therapy - p. 29 12. Section II: Surgical Oncology - p. 39 13. Neoadjuvant Therapy in Resectable Melanoma: Current Evidence and Future Directions - p. 41 14. Current Indications for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Gastrointestinal Malignancies - p. 49 15. Precision Medicine for Pancreatic Cancer - p. 63 16. Section III: Medical Oncology - p. 71 17. Recognition and Management of Toxicities from Immunotherapy and Targeted Therapy in Elderly Patients with Lung Cancer - p. 73 18. Expanding the Role of Checkpoint Inhibitors in Immune Cold Tumors - p. 85 19. Precision Oncology: Current Scenario and Future Promises and Challenges - p. 97 20. Section IV: Gynecologic Oncology - p. 112 21. Challenges and Opportunities for Immunotherapy in Gynecologic Cancer - p. 113 22. Minimally Invasive Surgery in Gynecologic Cancers - p. 125 23. Present and Future for PARP Inhibitors in Ovarian Cancer - p. 139 24. Section V: Pediatric Oncology - p. 154 25. Advances in Pediatric Radiation Oncology: Proton Therapy - p. 155 26. Updates in Childhood Leukemia - p. 169 27. Advances in Neuroblastoma and Wilms Tumor - p. 181 28. Section VI: Neuro-Oncology - p. 181 29. Gene Therapy for the Treatment of Malignant Glioma - p. 189 30. The Evolving Role of Targeted Therapies in Primary Central Nervous System Tumors - p. 203 31. A Physical Perspective on Oncology Research: The Critically Emerging Role of Physical Science in the Fight Against Brain Cancer - p. 213 32. Section VII: Hematological-Oncology - p. 213 33. Advances in Cellular Immunotherapy in Hematologic Malignancies - p. 223 34. Focus on Novel Therapies for Older Adults with Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes - p. 237 35. Eradicating Minimal Residual Disease in Chronic Lymphocytic Leukemia - p. 249 36. Section VIII: Uro-Oncology - p. 262 37. Recent Advances in the Treatment of Metastatic Prostate Cancer - p. 263 38. The Landscape of Antibody-drug Conjugates in Urothelial Cancer: Current Data and Future Perspectives - p. 273 39. Section IX: Gastrointestinal Oncology - p. 282 40. Immunotherapy for GI Cancers: Who Benefits, Who Does Not, and Promising Strategies to Expand Use - p. 283 41. Advances in Treatment Selection for Patients with Metastatic Colorectal Cancer - p. 297 42. Molecular Determinants of Gastrointestinal Cancers - p. 311
This premier volume of Advances in Oncology highlights the latest findings and updates within the cancer field each year for the practicing oncologist. Advances in Oncology publishes the most current thinking and recent advances from the voice of a truly distinguished editorial board, including Editor-in-Chief Leonidas C. Platanias, who identify current advances and breakthroughs in the field and invite specialists to contribute original articles on these topics. Topics discussed in this first volume are within the areas of radiation oncology, surgical oncology, medical oncology, gynecologic oncology, pediatric oncology, neuro-oncology, hemato-oncology, uro-oncology, and gastrointestinal oncology. This volume will appeal to all practicing oncologists and will inform and enhance clinical practice.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Editorial Board - p. iii 6. Contributors - p. v 7. Preface - p. xix 8. Section I: Radiation Oncology - p. xix 9. Radiation-Induced Cardiotoxicity: From Bench to Bedside and Beyond - p. 1 10. Radiotherapy for Metastatic Non–Small Cell Lung Cancer: An Emerging Tool for Systemic Control - p. 15 11. MRI-Guided Radiation Therapy - p. 29 12. Section II: Surgical Oncology - p. 39 13. Neoadjuvant Therapy in Resectable Melanoma: Current Evidence and Future Directions - p. 41 14. Current Indications for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Gastrointestinal Malignancies - p. 49 15. Precision Medicine for Pancreatic Cancer - p. 63 16. Section III: Medical Oncology - p. 71 17. Recognition and Management of Toxicities from Immunotherapy and Targeted Therapy in Elderly Patients with Lung Cancer - p. 73 18. Expanding the Role of Checkpoint Inhibitors in Immune Cold Tumors - p. 85 19. Precision Oncology: Current Scenario and Future Promises and Challenges - p. 97 20. Section IV: Gynecologic Oncology - p. 112 21. Challenges and Opportunities for Immunotherapy in Gynecologic Cancer - p. 113 22. Minimally Invasive Surgery in Gynecologic Cancers - p. 125 23. Present and Future for PARP Inhibitors in Ovarian Cancer - p. 139 24. Section V: Pediatric Oncology - p. 154 25. Advances in Pediatric Radiation Oncology: Proton Therapy - p. 155 26. Updates in Childhood Leukemia - p. 169 27. Advances in Neuroblastoma and Wilms Tumor - p. 181 28. Section VI: Neuro-Oncology - p. 181 29. Gene Therapy for the Treatment of Malignant Glioma - p. 189 30. The Evolving Role of Targeted Therapies in Primary Central Nervous System Tumors - p. 203 31. A Physical Perspective on Oncology Research: The Critically Emerging Role of Physical Science in the Fight Against Brain Cancer - p. 213 32. Section VII: Hematological-Oncology - p. 213 33. Advances in Cellular Immunotherapy in Hematologic Malignancies - p. 223 34. Focus on Novel Therapies for Older Adults with Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes - p. 237 35. Eradicating Minimal Residual Disease in Chronic Lymphocytic Leukemia - p. 249 36. Section VIII: Uro-Oncology - p. 262 37. Recent Advances in the Treatment of Metastatic Prostate Cancer - p. 263 38. The Landscape of Antibody-drug Conjugates in Urothelial Cancer: Current Data and Future Perspectives - p. 273 39. Section IX: Gastrointestinal Oncology - p. 282 40. Immunotherapy for GI Cancers: Who Benefits, Who Does Not, and Promising Strategies to Expand Use - p. 283 41. Advances in Treatment Selection for Patients with Metastatic Colorectal Cancer - p. 297 42. Molecular Determinants of Gastrointestinal Cancers - p. 311
