Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals.
1. Chapter 1 : The aging: introduction, theories, principles, and future prospective - p. Page x 2. Chapter 2 : Impact of aging at cellular and organ level - p. Page 14 3. Chapter 3 : Brief about hallmarks of aging - p. Page 33 4. Chapter 4 : Overview of various antiaging strategies - p. Page 57 5. Chapter 5 : Elimination of damaged cells-dependent antiaging strategy - p. Page 69 6. Chapter 6 : Telomerase reactivation for anti-aging - p. Page 103 7. Chapter 7 : Epigenetic drugs based on antiaging approach: an overview - p. Page 123 8. Chapter 8 : Exploring the role of protein quality control in aging and age-associated neurodegenerative diseases - p. Page 135 9. Chapter 9 : Dietary restriction and mTOR and IIS inhibition: the potential to antiaging drug approach - p. Page 162 10. Chapter 10 : Antiaging drugs, candidates, and food supplements: the journey so far - p. Page 184 11. Chapter 11 : Role of AMP-activated protein kinase and sirtuins as antiaging proteins - p. Page 232 12. Chapter 12 : Mitophagy and mitohormetics: promising antiaging strategy - p. Page 268 13. Chapter 13 : Clearance of senescent cells: potent anti-aging approach - p. Page 286 14. Chapter 14 : Stem cell-based therapy as an antiaging prospective - p. Page 301 15. Chapter 15 : Antiinflammatory therapy as a game-changer toward antiaging - p. Page 322 16. Chapter 16 : Invertebrate model organisms for aging research - p. Page 344 17. Index - p. Page 375
Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging is a comprehensive and timely book on all aspects of anti-aging strategies. The book provides comprehensive, foundational knowledge on the mechanisms of aging and current anti-aging strategies and approaches developed. Aging research has experienced an unprecedented advance over recent years with the discovery that the rate of aging is determined, at least to some extent, mainly by our genetics and modulated by environmental factors. The hallmarks of aging describe the molecular and cellular processes that govern biological aging and their variation in individuals.
1. Chapter 1 : The aging: introduction, theories, principles, and future prospective - p. Page x 2. Chapter 2 : Impact of aging at cellular and organ level - p. Page 14 3. Chapter 3 : Brief about hallmarks of aging - p. Page 33 4. Chapter 4 : Overview of various antiaging strategies - p. Page 57 5. Chapter 5 : Elimination of damaged cells-dependent antiaging strategy - p. Page 69 6. Chapter 6 : Telomerase reactivation for anti-aging - p. Page 103 7. Chapter 7 : Epigenetic drugs based on antiaging approach: an overview - p. Page 123 8. Chapter 8 : Exploring the role of protein quality control in aging and age-associated neurodegenerative diseases - p. Page 135 9. Chapter 9 : Dietary restriction and mTOR and IIS inhibition: the potential to antiaging drug approach - p. Page 162 10. Chapter 10 : Antiaging drugs, candidates, and food supplements: the journey so far - p. Page 184 11. Chapter 11 : Role of AMP-activated protein kinase and sirtuins as antiaging proteins - p. Page 232 12. Chapter 12 : Mitophagy and mitohormetics: promising antiaging strategy - p. Page 268 13. Chapter 13 : Clearance of senescent cells: potent anti-aging approach - p. Page 286 14. Chapter 14 : Stem cell-based therapy as an antiaging prospective - p. Page 301 15. Chapter 15 : Antiinflammatory therapy as a game-changer toward antiaging - p. Page 322 16. Chapter 16 : Invertebrate model organisms for aging research - p. Page 344 17. Index - p. Page 375
