Axon Regrowth: The Neurobiology of Nerve and Axon Regeneration, originally published in 2008 and now fully revised—with a refocus on the central nervous system and axon regeneration—emphasizes the commonalities and differences with peripheral nerve regeneration. The book reviews the substantial problems of axon and nerve regeneration, including molecular mechanisms and the approaches that can be used to experimentally address new avenues. Both researchers and clinicians alike will consider this a valuable resource.
1. Chapter 1 Introduction - p. 1 2. Chapter 2 The intact peripheral nerve tree - p. 7 3. Chapter 3 Nerve injuries and neuropathies - p. 35 4. Chapter 4 Axonal degeneration - p. 57 5. Chapter 5 Addressing nerve regeneration - p. 75 6. Chapter 6 Early regenerative events - p. 103 7. Chapter 7 Growth factors and extrinsic determinants of growth - p. 147 8. Chapter 8 Intrinsic growth signaling pathways within neurons - p. 179 9. Chapter 9 Schwann cell biology and regeneration - p. 197 10. Chapter 10 Maturation of regeneration and reinnervation - p. 217 11. Chapter 11 Delayed reinnervation - p. 239 12. Chapter 12 Sensory ganglia and regeneration - p. 249 13. Chapter 13 Axon regeneration in the central nervous system - p. 279 14. 13.1 Major forms of CNS axonopathy - p. 279 15. 13.2 Overall considerations - p. 286 16. 13.3 Molecular determinants, including barriers to CNS axon growth - p. 288 17. 13.4 Summary - p. 293 18. Further reading - p. 293 19. Chapter 14 Nerve repair⋆ - p. 295 20. 14.1 Acute traumatic neurotmesis - p. 295 21. 14.2 Neurotization and end-to-side nerve repair - p. 302 22. 14.3 Nonsurgical strategies for enhancing nerve regeneration - p. 303 23. 14.4 Nerve transfer surgeries - p. 305 24. 14.5 Root reimplantation - p. 305 25. 14.6 Clinical nerve repair in specific territories - p. 306 26. 14.7 Nerve injury and gunshot injuries - p. 307 27. 14.8 Neuromas - p. 308 28. 14.9 Decompression for entrapment neuropathies - p. 311 29. 14.10 Summary - p. 314 30. Further reading - p. 314 31. References - p. 315 32. Index - p. 369
Axon Regrowth: The Neurobiology of Nerve and Axon Regeneration, originally published in 2008 and now fully revised—with a refocus on the central nervous system and axon regeneration—emphasizes the commonalities and differences with peripheral nerve regeneration. The book reviews the substantial problems of axon and nerve regeneration, including molecular mechanisms and the approaches that can be used to experimentally address new avenues. Both researchers and clinicians alike will consider this a valuable resource.
1. Chapter 1 Introduction - p. 1 2. Chapter 2 The intact peripheral nerve tree - p. 7 3. Chapter 3 Nerve injuries and neuropathies - p. 35 4. Chapter 4 Axonal degeneration - p. 57 5. Chapter 5 Addressing nerve regeneration - p. 75 6. Chapter 6 Early regenerative events - p. 103 7. Chapter 7 Growth factors and extrinsic determinants of growth - p. 147 8. Chapter 8 Intrinsic growth signaling pathways within neurons - p. 179 9. Chapter 9 Schwann cell biology and regeneration - p. 197 10. Chapter 10 Maturation of regeneration and reinnervation - p. 217 11. Chapter 11 Delayed reinnervation - p. 239 12. Chapter 12 Sensory ganglia and regeneration - p. 249 13. Chapter 13 Axon regeneration in the central nervous system - p. 279 14. 13.1 Major forms of CNS axonopathy - p. 279 15. 13.2 Overall considerations - p. 286 16. 13.3 Molecular determinants, including barriers to CNS axon growth - p. 288 17. 13.4 Summary - p. 293 18. Further reading - p. 293 19. Chapter 14 Nerve repair⋆ - p. 295 20. 14.1 Acute traumatic neurotmesis - p. 295 21. 14.2 Neurotization and end-to-side nerve repair - p. 302 22. 14.3 Nonsurgical strategies for enhancing nerve regeneration - p. 303 23. 14.4 Nerve transfer surgeries - p. 305 24. 14.5 Root reimplantation - p. 305 25. 14.6 Clinical nerve repair in specific territories - p. 306 26. 14.7 Nerve injury and gunshot injuries - p. 307 27. 14.8 Neuromas - p. 308 28. 14.9 Decompression for entrapment neuropathies - p. 311 29. 14.10 Summary - p. 314 30. Further reading - p. 314 31. References - p. 315 32. Index - p. 369
