Both basic science and clinical immunology are demystified here for the medical and other health sciences student. The basic immunological processes are described first, with a level of detail restricted to only what is appropriate for medical (and similar) curricula. In the second part of the book, immunological mechanisms behind major diseases of the various body systems are clearly explained. Clinical details are highlighted throughout and the more in-depth material is differentiated from the main text.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Preface to the second edition - p. iii 6. Preface to the first edition - p. v 7. Symbols used in the diagrams - p. vi 8. List of Illustrations - p. viii 9. List of Tables - p. viii 10. Chapter 1: Anatomy and cells of the immune system - p. viii 11. Chapter 2: Innate immunity I: physical and humoral protection - p. 9 12. Chapter 3: Innate immunity II: cellular mechanisms - p. 22 13. Chapter 4: Acquired immunity: antigen receptors - p. 34 14. Chapter 5: The human leukocyte antigens - p. 53 15. Chapter 6: Cellular immune responses I: dendritic cells, macrophages and B lymphocytes - p. 70 16. Chapter 7: Cellular immune responses II: T lymphocytes, antigen presentation and natural killer cells - p. 85 17. Chapter 8: The immune response to microbes: an overview - p. 114 18. Chapter 9: Tolerance and mechanisms of autoimmunity - p. 120 19. Chapter 10: Hypersensitivity reactions and clinical allergy - p. 132 20. Chapter 11: Transplantation - p. 150 21. Chapter 12: Rheumatic diseases - p. 165 22. Chapter 13: Endocrine autoimmune disease - p. 188 23. Chapter 14: Liver diseases - p. 202 24. Chapter 15: Gastrointestinal diseases - p. 210 25. Chapter 16: Immune-mediated nephritis and vasculitis - p. 218 26. Chapter 17: Immune-mediated skin disease - p. 237 27. Chapter 18: Immune-mediated diseases of the nervous system and eye - p. 248 28. Chapter 19: Immunodeficiency - p. 263 29. Chapter 20: Human immunodeficiency virus and AIDS - p. 281 30. Chapter 21: Immunological manifestations of haematological disease - p. 292 31. Chapter 22: Immune-based therapies - p. 305 32. Chapter 23: Immunisation - p. 322 33. Appendices - p. 332 34. Commonly encountered CD molecules - p. 332 35. Major cytokines, cells releasing them, targets and functions - p. 341 36. List of class II human leukocyte antigen alleles - p. 345 37. Abbreviations used for amino acids - p. 346 38. Index - p. 347
Both basic science and clinical immunology are demystified here for the medical and other health sciences student. The basic immunological processes are described first, with a level of detail restricted to only what is appropriate for medical (and similar) curricula. In the second part of the book, immunological mechanisms behind major diseases of the various body systems are clearly explained. Clinical details are highlighted throughout and the more in-depth material is differentiated from the main text.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Preface to the second edition - p. iii 6. Preface to the first edition - p. v 7. Symbols used in the diagrams - p. vi 8. List of Illustrations - p. viii 9. List of Tables - p. viii 10. Chapter 1: Anatomy and cells of the immune system - p. viii 11. Chapter 2: Innate immunity I: physical and humoral protection - p. 9 12. Chapter 3: Innate immunity II: cellular mechanisms - p. 22 13. Chapter 4: Acquired immunity: antigen receptors - p. 34 14. Chapter 5: The human leukocyte antigens - p. 53 15. Chapter 6: Cellular immune responses I: dendritic cells, macrophages and B lymphocytes - p. 70 16. Chapter 7: Cellular immune responses II: T lymphocytes, antigen presentation and natural killer cells - p. 85 17. Chapter 8: The immune response to microbes: an overview - p. 114 18. Chapter 9: Tolerance and mechanisms of autoimmunity - p. 120 19. Chapter 10: Hypersensitivity reactions and clinical allergy - p. 132 20. Chapter 11: Transplantation - p. 150 21. Chapter 12: Rheumatic diseases - p. 165 22. Chapter 13: Endocrine autoimmune disease - p. 188 23. Chapter 14: Liver diseases - p. 202 24. Chapter 15: Gastrointestinal diseases - p. 210 25. Chapter 16: Immune-mediated nephritis and vasculitis - p. 218 26. Chapter 17: Immune-mediated skin disease - p. 237 27. Chapter 18: Immune-mediated diseases of the nervous system and eye - p. 248 28. Chapter 19: Immunodeficiency - p. 263 29. Chapter 20: Human immunodeficiency virus and AIDS - p. 281 30. Chapter 21: Immunological manifestations of haematological disease - p. 292 31. Chapter 22: Immune-based therapies - p. 305 32. Chapter 23: Immunisation - p. 322 33. Appendices - p. 332 34. Commonly encountered CD molecules - p. 332 35. Major cytokines, cells releasing them, targets and functions - p. 341 36. List of class II human leukocyte antigen alleles - p. 345 37. Abbreviations used for amino acids - p. 346 38. Index - p. 347
