Biofabrication and Synthetic Biology in Medicinal Plants: Advances in Biotechnology and Breeding presents recent technological advances for enhancing medicinal plants as sources of plant-based biopharmaceuticals. It covers biofabrication, synthetic biology, modern biotechnological tools, and innovative breeding strategies tailored for medicinal plant improvement. While these technologies are well established in crop plants, their application in medicinal plants remains underexplored. Medicinal plants are rich sources of therapeutic compounds traditionally used across cultures to treat a wide range of diseases and health conditions. These plants produce diverse bioactive molecules, including terpenoids, flavonoids, alkaloids, and phenolics, many of which exhibit significant pharmacological potential. For centuries, medicinal and aromatic plants have played a vital role in human healthcare and continue to be valued globally. Recent advances in synthetic biology, metabolic engineering, and biotechnology promise to enhance the production, quality, and efficacy of these bioactive compounds, addressing unmet medical needs and contributing to sustainable healthcare. This book compiles insights from leading experts, offering a comprehensive reference for researchers, early-career scientists, students, and professionals working in medicinal plant biotechnology and breeding.
• Explores topics from plant extraction and bioactive compound identification to genetic engineering applications in plant-based medicine
• Highlights scientific validation of traditional remedies and the use of synthetic biology to improve compound production and efficacy
• Includes case studies illustrating real-world applications of synthetic biology in medicinal plants
• Identifies opportunities and challenges in applying biotechnology and breeding to lesser-known medicinal and aromatic species
1. Title of Book - p. i 2. Cover Image - p. i 3. Title Page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Contributors - p. xvii 7. Chapter 1 Medicinal plants: Ancient practice for eradication of global diseases - p. 1 8. Chapter 2 Bioactive compounds of medicinal plants and their role in preventing infectious diseases - p. 21 9. Chapter 3 Conservation of medicinal and aromatic plants: Current efforts, challenges and future perspectives - p. 41 10. Chapter 4 Biofabrication of nanoparticles from medicinal plants: Challenges and future perspectives - p. 59 11. Chapter 5 Intellectual property right law and traditional knowledge of medicinal plants - p. 83 12. Chapter 6 Biotechnological production of phytoconstituents to pure molecules - p. 93 13. Chapter 7 Conventional and advanced methods of phyto-constituent recovery - p. 103 14. Chapter 8 Green synthesis of nanoparticles and technological advances in analysis of biofabricated nanoparticles - p. 117 15. Chapter 9 Combinatorial approches of MAPs and nanotechnology and its applications - p. 133 16. Chapter 10 In silico prediction tools of plant-based precision medicine - p. 147 17. Chapter 11 Biotechnological paradigms for augmenting secondary metabolite biosynthesis in medicinal flora - p. 163 18. Chapter 12 Genetic innovations shaping medicinal plant research: Advancements in genomic variability and architecture - p. 175 19. Chapter 13 Advances in plant tissue culture techniques for rapid propagation and conservation of medicinally valuable plant species - p. 189 20. Chapter 14 Manipulating biosynthetic pathways for controlled secondary metabolite production - p. 211 21. Chapter 15 Perspectives, problems, and possible solutions in Nutriomics and Ayurgenomics of medicinal plants with case studies - p. 235 22. Chapter 16 Utilization of computational resources for genomic data mining and integration in medicinal plant breeding initiatives - p. 259 23. Chapter 17 Bioengineering of plant natural products: Concepts and processes in synthetic biology - p. 273 24. Chapter 18 Role of synthetic biology in biodrug production and human wellness - p. 291 25. Chapter 19 Synthetic biology based production systems of bioactive compounds - p. 311 26. Chapter 20 Synthetic biology based reconstruction of pathway - p. 325 27. Chapter 21 Next-generation sequencing (NGS) techniques in improvement of medicinal plants - p. 345 28. Chapter 22 Advances in CRISPR-Cas9 technology in synthetic biology - p. 365 29. Chapter 23 Enzyme engineering in medicinal plants: Enhancements in the yield of secondary metabolites - p. 379 30. Chapter 24 Network pharmacology approach for medicinal plants - p. 401 31. Chapter 25 Biosafety concerns and ethical aspects of synthetic biology - p. 415 32. Chapter 26 Pharmacological potential of engineered medicinal flora: Case studies and future perspectives - p. 439 33. Index - p. 453
Biofabrication and Synthetic Biology in Medicinal Plants: Advances in Biotechnology and Breeding presents recent technological advances for enhancing medicinal plants as sources of plant-based biopharmaceuticals. It covers biofabrication, synthetic biology, modern biotechnological tools, and innovative breeding strategies tailored for medicinal plant improvement. While these technologies are well established in crop plants, their application in medicinal plants remains underexplored. Medicinal plants are rich sources of therapeutic compounds traditionally used across cultures to treat a wide range of diseases and health conditions. These plants produce diverse bioactive molecules, including terpenoids, flavonoids, alkaloids, and phenolics, many of which exhibit significant pharmacological potential. For centuries, medicinal and aromatic plants have played a vital role in human healthcare and continue to be valued globally. Recent advances in synthetic biology, metabolic engineering, and biotechnology promise to enhance the production, quality, and efficacy of these bioactive compounds, addressing unmet medical needs and contributing to sustainable healthcare. This book compiles insights from leading experts, offering a comprehensive reference for researchers, early-career scientists, students, and professionals working in medicinal plant biotechnology and breeding.
• Explores topics from plant extraction and bioactive compound identification to genetic engineering applications in plant-based medicine
• Highlights scientific validation of traditional remedies and the use of synthetic biology to improve compound production and efficacy
• Includes case studies illustrating real-world applications of synthetic biology in medicinal plants
• Identifies opportunities and challenges in applying biotechnology and breeding to lesser-known medicinal and aromatic species
1. Title of Book - p. i 2. Cover Image - p. i 3. Title Page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Contributors - p. xvii 7. Chapter 1 Medicinal plants: Ancient practice for eradication of global diseases - p. 1 8. Chapter 2 Bioactive compounds of medicinal plants and their role in preventing infectious diseases - p. 21 9. Chapter 3 Conservation of medicinal and aromatic plants: Current efforts, challenges and future perspectives - p. 41 10. Chapter 4 Biofabrication of nanoparticles from medicinal plants: Challenges and future perspectives - p. 59 11. Chapter 5 Intellectual property right law and traditional knowledge of medicinal plants - p. 83 12. Chapter 6 Biotechnological production of phytoconstituents to pure molecules - p. 93 13. Chapter 7 Conventional and advanced methods of phyto-constituent recovery - p. 103 14. Chapter 8 Green synthesis of nanoparticles and technological advances in analysis of biofabricated nanoparticles - p. 117 15. Chapter 9 Combinatorial approches of MAPs and nanotechnology and its applications - p. 133 16. Chapter 10 In silico prediction tools of plant-based precision medicine - p. 147 17. Chapter 11 Biotechnological paradigms for augmenting secondary metabolite biosynthesis in medicinal flora - p. 163 18. Chapter 12 Genetic innovations shaping medicinal plant research: Advancements in genomic variability and architecture - p. 175 19. Chapter 13 Advances in plant tissue culture techniques for rapid propagation and conservation of medicinally valuable plant species - p. 189 20. Chapter 14 Manipulating biosynthetic pathways for controlled secondary metabolite production - p. 211 21. Chapter 15 Perspectives, problems, and possible solutions in Nutriomics and Ayurgenomics of medicinal plants with case studies - p. 235 22. Chapter 16 Utilization of computational resources for genomic data mining and integration in medicinal plant breeding initiatives - p. 259 23. Chapter 17 Bioengineering of plant natural products: Concepts and processes in synthetic biology - p. 273 24. Chapter 18 Role of synthetic biology in biodrug production and human wellness - p. 291 25. Chapter 19 Synthetic biology based production systems of bioactive compounds - p. 311 26. Chapter 20 Synthetic biology based reconstruction of pathway - p. 325 27. Chapter 21 Next-generation sequencing (NGS) techniques in improvement of medicinal plants - p. 345 28. Chapter 22 Advances in CRISPR-Cas9 technology in synthetic biology - p. 365 29. Chapter 23 Enzyme engineering in medicinal plants: Enhancements in the yield of secondary metabolites - p. 379 30. Chapter 24 Network pharmacology approach for medicinal plants - p. 401 31. Chapter 25 Biosafety concerns and ethical aspects of synthetic biology - p. 415 32. Chapter 26 Pharmacological potential of engineered medicinal flora: Case studies and future perspectives - p. 439 33. Index - p. 453
