Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xiii 7. Preface - p. xvii 8. Chapter One. Milestones in cancer research - p. 1 9. Chapter Two. Cancer burden: Epidemiology, racial, and geographical disparities - p. 15 10. Chapter Three. Technological evolution in cancer diagnosis and therapeutics - p. 33 11. Chapter Four. How does time speak about cancer, its diagnosis, treatments, and challenges? - p. 71 12. Chapter Five. Role of artificial intelligence in cancer diagnostics and therapeutics - p. 86 13. Chapter Six. Addressing the diagnosis and therapeutics of malignant tumor cells - p. 99 14. Chapter Seven. Insights into genetic predisposition of somatic cancers - p. 117 15. Chapter Eight. The use of tumor markers in prognosis of cancer and strategies to prevent cancer predisposition and progress - p. 125 16. Chapter Nine. Cytogenetics to multiomics in biology of cancer - p. 155 17. Chapter Ten. Role of noncoding RNA as biomarkers for cancer - p. 187 18. Chapter Eleven. Viral miRNAs role as diagnostic, prognostic biomarkers for cancer and infectious diseases - p. 206 19. Chapter Twelve. Pharmacogenomics and oncology: A therapeutic approach for cancer treatment - p. 229 20. Chapter Thirteen. Obesity: Emerging risk factor for cancer beyond metabolic syndrome - p. 245 21. Chapter Fourteen. Homologous repair deficiency and PARP inhibitors in cancer management - p. 257 22. Chapter Fifteen. Molecular prospects of transcription activator-like effector nucleases (TALENs) in cancer management: Challenges and adaptations - p. 275 23. Chapter Sixteen. Immunopeptidomic approaches for management of cancer - p. 285 24. Chapter Seventeen. Regulation of tumor microenvironment by nutrient trafficking - p. 297 25. Chapter Eighteen. Environmental factors influencing epigenetic changes initiating neoplastic changes - p. 323 26. Chapter Nineteen. Somatic mutation: Pharmacogenomics in oncology care - p. 331 27. Chapter Twenty. Precision medicine: Dose for anticancer therapy - p. 357 28. Index - p. 369
Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xiii 7. Preface - p. xvii 8. Chapter One. Milestones in cancer research - p. 1 9. Chapter Two. Cancer burden: Epidemiology, racial, and geographical disparities - p. 15 10. Chapter Three. Technological evolution in cancer diagnosis and therapeutics - p. 33 11. Chapter Four. How does time speak about cancer, its diagnosis, treatments, and challenges? - p. 71 12. Chapter Five. Role of artificial intelligence in cancer diagnostics and therapeutics - p. 86 13. Chapter Six. Addressing the diagnosis and therapeutics of malignant tumor cells - p. 99 14. Chapter Seven. Insights into genetic predisposition of somatic cancers - p. 117 15. Chapter Eight. The use of tumor markers in prognosis of cancer and strategies to prevent cancer predisposition and progress - p. 125 16. Chapter Nine. Cytogenetics to multiomics in biology of cancer - p. 155 17. Chapter Ten. Role of noncoding RNA as biomarkers for cancer - p. 187 18. Chapter Eleven. Viral miRNAs role as diagnostic, prognostic biomarkers for cancer and infectious diseases - p. 206 19. Chapter Twelve. Pharmacogenomics and oncology: A therapeutic approach for cancer treatment - p. 229 20. Chapter Thirteen. Obesity: Emerging risk factor for cancer beyond metabolic syndrome - p. 245 21. Chapter Fourteen. Homologous repair deficiency and PARP inhibitors in cancer management - p. 257 22. Chapter Fifteen. Molecular prospects of transcription activator-like effector nucleases (TALENs) in cancer management: Challenges and adaptations - p. 275 23. Chapter Sixteen. Immunopeptidomic approaches for management of cancer - p. 285 24. Chapter Seventeen. Regulation of tumor microenvironment by nutrient trafficking - p. 297 25. Chapter Eighteen. Environmental factors influencing epigenetic changes initiating neoplastic changes - p. 323 26. Chapter Nineteen. Somatic mutation: Pharmacogenomics in oncology care - p. 331 27. Chapter Twenty. Precision medicine: Dose for anticancer therapy - p. 357 28. Index - p. 369
