Biophysical Basis of Physiology and Calcium Signaling Mechanism in Cardiac and Smooth Muscle acts as a bridge between physiology and physics by discussing the physiology and calcium signaling mechanism in cardiac and smooth muscle. By exploring the mechanism of the cyclic release of stored Ca^(2+) in the SR or ER, this book covers the cell communication system, including excitable cells, recognizing the most relevant mechanisms of cell communication. Serving as a bridge between physiology and physics, coverage spans the physiology and calcium signaling mechanism in cardiac and smooth muscle, offering insight to physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists.
1. Chapter 1: Introduction - p. xiii 2. Chapter 2: Statistical Thermodynamics - p. 14 3. Abstract - p. 15 4. 2.1 Introduction - p. 15 5. 2.2 Statistics of Energy Distribution Over Molecules - p. 16 6. 2.3 Derivation of the Boltzmann's Probability Distribution - p. 18 7. 2.4 Interacting System - p. 24 8. 2.5 Partition Functions and Degeneracy - p. 27 9. 2.6 Counting Microstates of Gasses - p. 28 10. 2.7 Changes in Energy and Enthalpy in Relation to Heat and Work on a System - p. 30 11. 2.8 Conditions of Spontaneity in Relation to Entropy and Free Energy - p. 34 12. 2.9 Statistical Definition of Entropy - p. 39 13. 2.10 Introduction of Partition Function to Thermodynamic Functions - p. 41 14. 2.11 Relationship Between Entropy and Microstates - p. 43 15. 2.12 Separation of Partition Function - p. 44 16. 2.13 Monatomic Gas as a Model of Ideal Gas - p. 46 17. 2.14 Calculation of Entropy and Free Energy Changes Statistically - p. 49 18. 2.15 Entropy and Diffusion - p. 55 19. 2.16 Double-Stranded DNA Model - p. 56 20. 2.17 Activation Energy - p. 58 21. 2.18 Changes in Gibbs Free Energy During Chemical Reactions - p. 60 22. Chapter 3: Shielding Effect and Chemical Bonding - p. 62 23. Chapter 4: The Cell - p. 97 24. Chapter 5: Diffusion and Flow, and Respiratory System - p. 137 25. Chapter 6: Peripheral Nervous Systems - p. 161 26. Chapter 7: Calcium Signaling in the Heart and Small Intestine - p. 185 27. Chapter 8: Mechanism of Cardiac Arrhythmias and Antiarrhythmic Drugs - p. 195 28. Reference Data - p. 209 29. Index - p. 211
Biophysical Basis of Physiology and Calcium Signaling Mechanism in Cardiac and Smooth Muscle acts as a bridge between physiology and physics by discussing the physiology and calcium signaling mechanism in cardiac and smooth muscle. By exploring the mechanism of the cyclic release of stored Ca^(2+) in the SR or ER, this book covers the cell communication system, including excitable cells, recognizing the most relevant mechanisms of cell communication. Serving as a bridge between physiology and physics, coverage spans the physiology and calcium signaling mechanism in cardiac and smooth muscle, offering insight to physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists.
1. Chapter 1: Introduction - p. xiii 2. Chapter 2: Statistical Thermodynamics - p. 14 3. Abstract - p. 15 4. 2.1 Introduction - p. 15 5. 2.2 Statistics of Energy Distribution Over Molecules - p. 16 6. 2.3 Derivation of the Boltzmann's Probability Distribution - p. 18 7. 2.4 Interacting System - p. 24 8. 2.5 Partition Functions and Degeneracy - p. 27 9. 2.6 Counting Microstates of Gasses - p. 28 10. 2.7 Changes in Energy and Enthalpy in Relation to Heat and Work on a System - p. 30 11. 2.8 Conditions of Spontaneity in Relation to Entropy and Free Energy - p. 34 12. 2.9 Statistical Definition of Entropy - p. 39 13. 2.10 Introduction of Partition Function to Thermodynamic Functions - p. 41 14. 2.11 Relationship Between Entropy and Microstates - p. 43 15. 2.12 Separation of Partition Function - p. 44 16. 2.13 Monatomic Gas as a Model of Ideal Gas - p. 46 17. 2.14 Calculation of Entropy and Free Energy Changes Statistically - p. 49 18. 2.15 Entropy and Diffusion - p. 55 19. 2.16 Double-Stranded DNA Model - p. 56 20. 2.17 Activation Energy - p. 58 21. 2.18 Changes in Gibbs Free Energy During Chemical Reactions - p. 60 22. Chapter 3: Shielding Effect and Chemical Bonding - p. 62 23. Chapter 4: The Cell - p. 97 24. Chapter 5: Diffusion and Flow, and Respiratory System - p. 137 25. Chapter 6: Peripheral Nervous Systems - p. 161 26. Chapter 7: Calcium Signaling in the Heart and Small Intestine - p. 185 27. Chapter 8: Mechanism of Cardiac Arrhythmias and Antiarrhythmic Drugs - p. 195 28. Reference Data - p. 209 29. Index - p. 211
