Biophysics of Tissue Self-Organization in Morphogenesis: The Role of Dynamics Along the Biointerface delves into the interactions between tissue and the extracellular matrix. It explores the fundamentals of cell self-rearrangement and the interrelation between biological mechanisms and physical principles responsible for tissue self-organization. The book examines modeling approaches to tissue self-organization and the application of engineering principles to solve medical problems. It also discusses tools, applications, and medical implications, particularly in embryo development, wound healing, and cancerous diseases, concluding with future developments.
Covering subcellular to supracellular levels, this book is an interdisciplinary guide for researchers in cell biology, biophysics, developmental biology, and more.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Section 1: Tissues self-organization in morphogenesis - p. S1 8. Chapter 1. Analysis of the effect of cell movement on gene expression dynamics in development - p. 3 9. Chapter 2. Force transmission across scales: examples and measuring methods - p. 41 10. Section 2: Physics of tissue self-organization from subcellular to supracellular levels - p. S57 11. Chapter 3. Cellular death and division events at tissue interfaces: a chicken-or-the-egg situation - p. 59 12. Chapter 4. Topological defects in multicellular systems - p. 95 13. Chapter 5. The dynamics along the epithelial–cancer biointerface within cocultured cell spheroids: physical aspects - p. 115 14. Chapter 6. Dynamic mechanical three-way crosstalk at the interfaces of cancer cells, immune cells, like macrophages and stromal cells - p. 149 15. Chapter 7. Techniques for quantifying cell-scale dynamic mechanical interactions in extracellular matrices - p. 243 16. Section 3: Modelling of the tissue self-organization - p. S263 17. Chapter 8. Heterogeneity of leader–follower cell dynamics: a brief review of modelling approaches - p. 265 18. Section 4: Engineering of human tissues - p. S305 19. Chapter 9. Conclusion and outlook - p. 307 20. Index - p. 315
Biophysics of Tissue Self-Organization in Morphogenesis: The Role of Dynamics Along the Biointerface delves into the interactions between tissue and the extracellular matrix. It explores the fundamentals of cell self-rearrangement and the interrelation between biological mechanisms and physical principles responsible for tissue self-organization. The book examines modeling approaches to tissue self-organization and the application of engineering principles to solve medical problems. It also discusses tools, applications, and medical implications, particularly in embryo development, wound healing, and cancerous diseases, concluding with future developments.
Covering subcellular to supracellular levels, this book is an interdisciplinary guide for researchers in cell biology, biophysics, developmental biology, and more.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Section 1: Tissues self-organization in morphogenesis - p. S1 8. Chapter 1. Analysis of the effect of cell movement on gene expression dynamics in development - p. 3 9. Chapter 2. Force transmission across scales: examples and measuring methods - p. 41 10. Section 2: Physics of tissue self-organization from subcellular to supracellular levels - p. S57 11. Chapter 3. Cellular death and division events at tissue interfaces: a chicken-or-the-egg situation - p. 59 12. Chapter 4. Topological defects in multicellular systems - p. 95 13. Chapter 5. The dynamics along the epithelial–cancer biointerface within cocultured cell spheroids: physical aspects - p. 115 14. Chapter 6. Dynamic mechanical three-way crosstalk at the interfaces of cancer cells, immune cells, like macrophages and stromal cells - p. 149 15. Chapter 7. Techniques for quantifying cell-scale dynamic mechanical interactions in extracellular matrices - p. 243 16. Section 3: Modelling of the tissue self-organization - p. S263 17. Chapter 8. Heterogeneity of leader–follower cell dynamics: a brief review of modelling approaches - p. 265 18. Section 4: Engineering of human tissues - p. S305 19. Chapter 9. Conclusion and outlook - p. 307 20. Index - p. 315
