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This issue of Hematology/Oncology Clinics, edited by Dr. Colin A. Sieff, will focus on Bone Marrow Failure. Topics include, but are not limited to, Acquired and Inherited Bone Marrow Failure; Kickapoo Joy Juice and Somatic Mutations in the Pathogenesis of AA; Somatic Mutations in Aplastic Anemia; Recent Advances and Long-term Results of Medical Treatment of AA; Upfront Matched Unrelated Donor Transplantation in AA; Significance of Clonal Mutations in the Diagnosis and Management of Myelodysplastic Syndrome; Alternate (Haploidental) Donor Transplantation in AA; Management of Diamond Blackfan Anemia and Prospects for Novel Treatment; MDS, AML and Cancer Surveillance in Fanconi Anemia; Diagnosis, Treatment and Molecular Pathology of Shwachman Diamond Syndrome; Clinical Implications of Clonal Hematopoiesis in Dyskeratosis congenita; and Germline GATA2 Mutations and Bone Marrow Failure.

1. Introduction to Acquired and Inherited Bone Marrow Failure - p. 569 2. The Pathophysiology of Acquired Aplastic Anemia: Current Concepts Revisited - p. 581 3. Somatic Mutations in Aplastic Anemia - p. 595 4. Recent Advances and Long-Term Results of Medical Treatment of Acquired Aplastic Anemia: Are Patients Cured? - p. 609 5. Upfront Matched Unrelated Donor Transplantation in Aplastic Anemia - p. 619 6. Haploidentical Donor Bone Marrow Transplantation for Severe Aplastic Anemia - p. 629 7. Significance of Clonal Mutations in Bone Marrow Failure and Inherited Myelodysplastic Syndrome/Acute Myeloid Leukemia Predisposition Syndromes - p. 643 8. Myelodysplastic Syndrome, Acute Myeloid Leukemia, and Cancer Surveillance in Fanconi Anemia - p. 657 9. Evaluation and Management of Hematopoietic Failure in Dyskeratosis Congenita - p. 669 10. Diagnosis, Treatment, and Molecular Pathology of Shwachman-Diamond Syndrome - p. 687 11. Critical Issues in Diamond-Blackfan Anemia and Prospects for Novel Treatment - p. 701 12. Germline GATA2 Mutation and Bone Marrow Failure - p. 713 13. Monosomy 7 in Pediatric Myelodysplastic Syndromes - p. 729

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This issue of Hematology/Oncology Clinics, edited by Dr. Colin A. Sieff, will focus on Bone Marrow Failure. Topics include, but are not limited to, Acquired and Inherited Bone Marrow Failure; Kickapoo Joy Juice and Somatic Mutations in the Pathogenesis of AA; Somatic Mutations in Aplastic Anemia; Recent Advances and Long-term Results of Medical Treatment of AA; Upfront Matched Unrelated Donor Transplantation in AA; Significance of Clonal Mutations in the Diagnosis and Management of Myelodysplastic Syndrome; Alternate (Haploidental) Donor Transplantation in AA; Management of Diamond Blackfan Anemia and Prospects for Novel Treatment; MDS, AML and Cancer Surveillance in Fanconi Anemia; Diagnosis, Treatment and Molecular Pathology of Shwachman Diamond Syndrome; Clinical Implications of Clonal Hematopoiesis in Dyskeratosis congenita; and Germline GATA2 Mutations and Bone Marrow Failure.

1. Introduction to Acquired and Inherited Bone Marrow Failure - p. 569 2. The Pathophysiology of Acquired Aplastic Anemia: Current Concepts Revisited - p. 581 3. Somatic Mutations in Aplastic Anemia - p. 595 4. Recent Advances and Long-Term Results of Medical Treatment of Acquired Aplastic Anemia: Are Patients Cured? - p. 609 5. Upfront Matched Unrelated Donor Transplantation in Aplastic Anemia - p. 619 6. Haploidentical Donor Bone Marrow Transplantation for Severe Aplastic Anemia - p. 629 7. Significance of Clonal Mutations in Bone Marrow Failure and Inherited Myelodysplastic Syndrome/Acute Myeloid Leukemia Predisposition Syndromes - p. 643 8. Myelodysplastic Syndrome, Acute Myeloid Leukemia, and Cancer Surveillance in Fanconi Anemia - p. 657 9. Evaluation and Management of Hematopoietic Failure in Dyskeratosis Congenita - p. 669 10. Diagnosis, Treatment, and Molecular Pathology of Shwachman-Diamond Syndrome - p. 687 11. Critical Issues in Diamond-Blackfan Anemia and Prospects for Novel Treatment - p. 701 12. Germline GATA2 Mutation and Bone Marrow Failure - p. 713 13. Monosomy 7 in Pediatric Myelodysplastic Syndromes - p. 729

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