Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation.
1. Introduction - p. Page vi 2. List of Illustrations - p. Page xi 3. List of Tables - p. Page xii 4. Chapter 1 : Bone multiscale mechanics - p. Page xii 5. Chapter 2 : Bone remodeling biology - p. Page 42 6. Chapter 3 : Bone diseases and associated therapeutic solutions - p. Page 72 7. Chapter 4 : Bone remodeling mathematical models - p. Page 118 8. Chapter 5 : Bone and bone remodeling finite element modeling - p. Page 161 9. Chapter 6 : Bone remodeling: analysis, discussion, and perspectives - p. Page 201 10. Conclusion - p. Page 215 11. Index - p. Page 220
Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation.
1. Introduction - p. Page vi 2. List of Illustrations - p. Page xi 3. List of Tables - p. Page xii 4. Chapter 1 : Bone multiscale mechanics - p. Page xii 5. Chapter 2 : Bone remodeling biology - p. Page 42 6. Chapter 3 : Bone diseases and associated therapeutic solutions - p. Page 72 7. Chapter 4 : Bone remodeling mathematical models - p. Page 118 8. Chapter 5 : Bone and bone remodeling finite element modeling - p. Page 161 9. Chapter 6 : Bone remodeling: analysis, discussion, and perspectives - p. Page 201 10. Conclusion - p. Page 215 11. Index - p. Page 220
