Brain Energy Metabolism in Alzheimer’s Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer’s disease and related disorders.
Chapters in this release examine metabolic therapeutic targets in Alzheimer’s disease, alterations in brain energy metabolism in comparison with Parkinson’s disease, and the role of epigenetic modulation through natural compounds. Additional sections address mitochondrial dysfunction, disruption of metabolic pathways, and the contribution of glial cells to neurodegenerative processes.
Further contributions explore metabolic disorders linked to Parkinson’s disease, signaling pathways in neurodegeneration, and advances in therapeutic and diagnostic strategies targeting key enzymes. The volume also highlights the role of intestinal microbiota, nanocarrier-based therapeutic approaches, and emerging treatments such as HDAC inhibitors. Together, these chapters provide a comprehensive overview of the mechanisms, biomarkers, and therapeutic prospects related to energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Series Page - p. iii 6. Copyright - p. iv 7. Contributors - p. xv 8. Chapter One: Metabolic therapeutic targets in Alzheimer’s disease - p. 1 9. Chapter Two: Brain energy metabolism changes and neuropsychological impairment in Parkinson disease vs Alzheimer disease - p. 33 10. Chapter Three: Energetic crisis, mitochondrial vulnerability and disruption of lactate shuttle in Alzheimer’s disease - p. 67 11. Chapter Four: Astroglial dysregulation and gliotransmitter imbalance in schizophrenia - p. 91 12. Chapter Five: Molecular insights of peroxisome proliferator-activated receptor-γ signalling in amyotrophic lateral sclerosis and Huntington’s disease - p. 113 13. Chapter Six: A comprehensive review on therapeutics and diagnostic agents targeting acetyl and butyryl cholinesterases for AD - p. 145 14. Chapter Seven: Intestinal microbiota in neurodegeneration and ageing: Mechanisms, pathways, and therapeutic interventions - p. 199 15. Chapter Eight: Brain energy crisis in Alzheimer’s and Parkinson’s disease: Nanotechnology as a therapeutic strategy - p. 231 16. Chapter Nine: The potential of HDAC inhibitors for Alzheimer’s disease - p. 273 17. Chapter Ten: The Tau-mitochondria connection and its impact on cellular energy metabolism in Alzheimer’s disease - p. 299 18. Chapter Eleven: Brain lipid dysregulation as a driver of energy metabolism failure in Alzheimer’s disease - p. 363 19. Chapter Twelve: Metabolic dysregulation in Alzheimer’s disease: Mechanisms, markers, and therapeutic prospects - p. 397
Brain Energy Metabolism in Alzheimer’s Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer’s disease and related disorders.
Chapters in this release examine metabolic therapeutic targets in Alzheimer’s disease, alterations in brain energy metabolism in comparison with Parkinson’s disease, and the role of epigenetic modulation through natural compounds. Additional sections address mitochondrial dysfunction, disruption of metabolic pathways, and the contribution of glial cells to neurodegenerative processes.
Further contributions explore metabolic disorders linked to Parkinson’s disease, signaling pathways in neurodegeneration, and advances in therapeutic and diagnostic strategies targeting key enzymes. The volume also highlights the role of intestinal microbiota, nanocarrier-based therapeutic approaches, and emerging treatments such as HDAC inhibitors. Together, these chapters provide a comprehensive overview of the mechanisms, biomarkers, and therapeutic prospects related to energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Series Page - p. iii 6. Copyright - p. iv 7. Contributors - p. xv 8. Chapter One: Metabolic therapeutic targets in Alzheimer’s disease - p. 1 9. Chapter Two: Brain energy metabolism changes and neuropsychological impairment in Parkinson disease vs Alzheimer disease - p. 33 10. Chapter Three: Energetic crisis, mitochondrial vulnerability and disruption of lactate shuttle in Alzheimer’s disease - p. 67 11. Chapter Four: Astroglial dysregulation and gliotransmitter imbalance in schizophrenia - p. 91 12. Chapter Five: Molecular insights of peroxisome proliferator-activated receptor-γ signalling in amyotrophic lateral sclerosis and Huntington’s disease - p. 113 13. Chapter Six: A comprehensive review on therapeutics and diagnostic agents targeting acetyl and butyryl cholinesterases for AD - p. 145 14. Chapter Seven: Intestinal microbiota in neurodegeneration and ageing: Mechanisms, pathways, and therapeutic interventions - p. 199 15. Chapter Eight: Brain energy crisis in Alzheimer’s and Parkinson’s disease: Nanotechnology as a therapeutic strategy - p. 231 16. Chapter Nine: The potential of HDAC inhibitors for Alzheimer’s disease - p. 273 17. Chapter Ten: The Tau-mitochondria connection and its impact on cellular energy metabolism in Alzheimer’s disease - p. 299 18. Chapter Eleven: Brain lipid dysregulation as a driver of energy metabolism failure in Alzheimer’s disease - p. 363 19. Chapter Twelve: Metabolic dysregulation in Alzheimer’s disease: Mechanisms, markers, and therapeutic prospects - p. 397
