Cardiometabolic Dynamics: A Deep Dive into Health and Disease explores the intricate relationship between metabolic health and cardiovascular diseases, illuminating how cellular and molecular mechanisms contribute to metabolic dysregulation. The book delves into the ways metabolic pathologies act as precursors to cardiovascular conditions, including hypertension, atherosclerosis, cardiomyopathy, and heart failure. With a focus on healthy cardiometabolic dynamics, it underscores the crucial role they play in sustaining cardiovascular wellness, offering a comprehensive perspective on the intersection of metabolism and heart health.
The book further examines the influence of lifestyle factors, such as diet and exercise on cardiovascular metabolism and highlights emerging technologies like omics, genetic engineering, and wearable devices to advance research, diagnosis, and treatment.
1. Introduction - p. xxi 2. Section I. Foundational concepts: Cardiovascular physiology and metabolic pathways - p. S1 3. Chapter 1. Cardiac glucose metabolism - p. 3 4. Chapter 2. Lipid metabolism - p. 19 5. Chapter 3. Amino acid metabolism and protein homeostasis - p. 49 6. Chapter 4. Mitochondrial dysfunction in energy metabolism: Unraveling cardiometabolic diseases - p. 63 7. Section II. Metabolic regulation and cardiovascular diseases - p. S2 8. Chapter 5. Metabolic regulation and ischemic heart disease - p. 85 9. Chapter 6. Metabolic regulation in hypertrophic cardiomyopathy - p. 103 10. Chapter 7. Metabolic regulation and diabetic cardiomyopathy - p. 117 11. Chapter 8. Metabolic regulation and heart failure - p. 137 12. Chapter 9. Metabolic regulation in inherited cardiovascular diseases - p. 159 13. Chapter 10. Metabolic regulation and cardiac regeneration - p. 181 14. Section III. Research methodologies and innovations - p. S3 15. Chapter 11. Traditional and novel experimental models in metabolic and cardiovascular research - p. 201 16. Chapter 12. Emerging technologies in metabolic and cardiovascular research - p. 223 17. Chapter 13. Metabolic changes in cardiac dysfunction: Transcriptional mechanisms and key regulators - p. 241 18. Chapter 14. The interplay of metabolism and epigenetics in cardiovascular diseases - p. 269 19. Section IV. Therapeutic approaches and clinical implications - p. S4 20. Chapter 15. Pharmacological interventions of metabolic therapies - p. 297 21. Chapter 16. Diet and nutrition modifications for cardiovascular health - p. 313 22. Chapter 17. Metabolic regulation of the microbiome-dependent metabolites and cardiovascular function - p. 333 23. Chapter 18. Exercise and cardiovascular metabolism - p. 353 24. Index - p. 373
Cardiometabolic Dynamics: A Deep Dive into Health and Disease explores the intricate relationship between metabolic health and cardiovascular diseases, illuminating how cellular and molecular mechanisms contribute to metabolic dysregulation. The book delves into the ways metabolic pathologies act as precursors to cardiovascular conditions, including hypertension, atherosclerosis, cardiomyopathy, and heart failure. With a focus on healthy cardiometabolic dynamics, it underscores the crucial role they play in sustaining cardiovascular wellness, offering a comprehensive perspective on the intersection of metabolism and heart health.
The book further examines the influence of lifestyle factors, such as diet and exercise on cardiovascular metabolism and highlights emerging technologies like omics, genetic engineering, and wearable devices to advance research, diagnosis, and treatment.
1. Introduction - p. xxi 2. Section I. Foundational concepts: Cardiovascular physiology and metabolic pathways - p. S1 3. Chapter 1. Cardiac glucose metabolism - p. 3 4. Chapter 2. Lipid metabolism - p. 19 5. Chapter 3. Amino acid metabolism and protein homeostasis - p. 49 6. Chapter 4. Mitochondrial dysfunction in energy metabolism: Unraveling cardiometabolic diseases - p. 63 7. Section II. Metabolic regulation and cardiovascular diseases - p. S2 8. Chapter 5. Metabolic regulation and ischemic heart disease - p. 85 9. Chapter 6. Metabolic regulation in hypertrophic cardiomyopathy - p. 103 10. Chapter 7. Metabolic regulation and diabetic cardiomyopathy - p. 117 11. Chapter 8. Metabolic regulation and heart failure - p. 137 12. Chapter 9. Metabolic regulation in inherited cardiovascular diseases - p. 159 13. Chapter 10. Metabolic regulation and cardiac regeneration - p. 181 14. Section III. Research methodologies and innovations - p. S3 15. Chapter 11. Traditional and novel experimental models in metabolic and cardiovascular research - p. 201 16. Chapter 12. Emerging technologies in metabolic and cardiovascular research - p. 223 17. Chapter 13. Metabolic changes in cardiac dysfunction: Transcriptional mechanisms and key regulators - p. 241 18. Chapter 14. The interplay of metabolism and epigenetics in cardiovascular diseases - p. 269 19. Section IV. Therapeutic approaches and clinical implications - p. S4 20. Chapter 15. Pharmacological interventions of metabolic therapies - p. 297 21. Chapter 16. Diet and nutrition modifications for cardiovascular health - p. 313 22. Chapter 17. Metabolic regulation of the microbiome-dependent metabolites and cardiovascular function - p. 333 23. Chapter 18. Exercise and cardiovascular metabolism - p. 353 24. Index - p. 373
