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The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today’s students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.

  • Clearly written format incorporates rich illustrations, diagrams, and charts.
  • Uses real examples to illustrate key cell biology concepts.
  • Includes beneficial cell physiology coverage.
  • Clinically oriented text relates cell biology to pathophysiology and medicine.
  • Takes a mechanistic approach to molecular processes.
  • Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing.
  • Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation.
  • Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing.
  • Includes hundreds of new and updated diagrams and micrographs, plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail.

1. SECTION 1: Introduction - p. xiii 2. Chapter 1: History of Autopsy - p. xiii 3. Chapter 2: Autopsy Safety - p. I-1-5 4. SECTION 2: Autopsy Performance: External Examination - p. I-1-7 5. Chapter 3: Medical Intervention - p. I-1-7 6. Chapter 4: Postmortem Changes and External Examination - p. I-2-11 7. Autopsy Performance: Internal Examination - p. I-2-15 8. Chapter 5: Body Cavities - p. I-2-15 9. Chapter 6: Cardiovascular System - p. I-2-19 10. Chapter 7: Respiratory System - p. I-2-23 11. Chapter 8: Hematopoietic System - p. I-2-27 12. Chapter 9: Gastrointestinal System - p. I-2-33 13. Chapter 10: Hepatobiliary System - p. I-2-41 14. Chapter 11: Genitourinary System - p. I-2-47 15. Chapter 12: Endocrine System - p. I-2-53 16. Chapter 13: Central Nervous System - p. I-2-59 17. Chapter 14: Peripheral Nervous System - p. I-2-65 18. Chapter 15: Integumentary System - p. I-2-69 19. Chapter 16: Oral Cavity - p. I-2-73 20. Chapter 17: Medical Devices - p. I-2-77 21. Autopsy Performance: Laboratory Testing - p. I-2-81 22. Chapter 18: Chemistry - p. I-2-81 23. Chapter 19: Microbiology - p. I-2-83 24. Chapter 20: Cytology - p. I-2-87 25. Autopsy Performance: Postmortem Imaging - p. I-2-93 26. Chapter 21: Postmortem Radiography and Virtual Autopsy - p. I-2-93 27. SECTION 3: Autopsy Consent and Reporting: Autopsy Consent - p. I-2-99 28. Chapter 22: Consent Process and Legal Considerations - p. I-2-99 29. Autopsy Consent and Reporting: Autopsy Reporting - p. I-3-101 30. Chapter 23: Death Certificate - p. I-3-101 31. Chapter 24: Autopsy Report - p. I-3-105 32. Chapter 25: Presenting Autopsy Findings - p. I-3-107 33. PART II: Organ System Approach to Autopsy - p. I-3-109 34. SECTION 1: Sudden and Unexpected Death: Cardiovascular - p. I-3-109 35. Chapter 26: Pulmonary Thromboembolism - p. I-3-109 36. Chapter 27: Acute Myocardial Infarction - p. II-1-3 37. Chapter 28: Cardiomyopathy - p. II-1-7 38. Chapter 29: Myocarditis - p. II-1-11 39. Chapter 30: Cardiac Conduction System - p. II-1-17 40. Chapter 31: Aortic Dissection - p. II-1-23 41. Chapter 32: Abdominal Aortic Aneurysm - p. II-1-29 42. Sudden and Unexpected Death: Respiratory - p. II-1-31 43. Chapter 33: Pulmonary Edema - p. II-1-31 44. Chapter 34: Pulmonary Hemorrhage - p. II-1-35 45. Chapter 35: Tension Pneumothorax - p. II-1-39 46. Sudden and Unexpected Death: Gastrointestinal - p. II-1-43 47. Chapter 36: Upper Gastrointestinal Hemorrhage - p. II-1-43 48. Chapter 37: Lower Gastrointestinal Hemorrhage - p. II-1-47 49. Chapter 38: Intestinal Ischemia - p. II-1-51 50. Sudden and Unexpected Death: Hepatobiliary - p. II-1-55 51. Chapter 39: Hepatic Hemorrhage - p. II-1-55 52. Chapter 40: Hemorrhagic Pancreatitis - p. II-1-59 53. Chapter 41: Acute Liver Failure - p. II-1-63 54. Sudden and Unexpected Death: Genitourinary - p. II-1-67 55. Chapter 42: Pregnancy Complications - p. II-1-67 56. Chapter 43: Acute Renal Failure - p. II-1-73 57. Sudden and Unexpected Death: Endocrine - p. II-1-83 58. Chapter 44: Adrenal Insufficiency - p. II-1-83 59. Chapter 45: Adrenocortical Excess - p. II-1-87 60. Sudden and Unexpected Death: CNS - p. II-1-91 61. Chapter 46: Seizure Disorders - p. II-1-91 62. Chapter 47: Subdural Hemorrhage - p. II-1-95 63. Chapter 48: Subarachnoid Hemorrhage - p. II-1-99 64. Chapter 49: Stroke - p. II-1-103 65. SECTION 2: Postoperative/Post-Interventional Death: Iatrogenic - p. II-1-109 66. Chapter 50: Therapeutic Complications - p. II-1-109 67. Postoperative/Post-Interventional Death: Cardiovascular - p. II-2-113 68. Chapter 51: Coronary Artery Bypass Grafting - p. II-2-113 69. Chapter 52: Coronary Artery Stenting - p. II-2-117 70. Chapter 53: Valve Replacement (Including Transcatheter) - p. II-2-121 71. Chapter 54: Ventricular Assist Devices - p. II-2-127 72. Chapter 55: Thoracic Aortic Aneurysm Repair - p. II-2-131 73. Postoperative/Post-Interventional Death: Gastrointestinal and Hepatobiliary - p. II-2-137 74. Chapter 56: Pancreas Resection - p. II-2-137 75. Chapter 57: Gastrectomy and Esophagectomy - p. II-2-141 76. Chapter 58: Bariatric Surgery - p. II-2-145 77. Postoperative/Post-Interventional Death: CNS - p. II-2-149 78. Chapter 59: Central Nervous System Tumors - p. II-2-149 79. Chapter 60: Cerebral Aneurysm and Vascular Malformation - p. II-2-155 80. PART III: Disease Process Approach to Autopsy - p. II-2-161 81. SECTION 1: Transplantation - p. II-2-161 82. Chapter 61: Heart Transplant - p. II-2-161 83. Chapter 62: Lung Transplant - p. III-1-7 84. Chapter 63: Kidney Transplant - p. III-1-11 85. Chapter 64: Liver Transplant - p. III-1-21 86. Chapter 65: Pancreas Transplant - p. III-1-27 87. Chapter 66: Bone Marrow Transplant - p. III-1-31 88. Chapter 67: Deceased Donor Autopsy - p. III-1-35 89. SECTION 2: Infection-Related Death: Systemic Infection/Sepsis Overview - p. III-1-37 90. Chapter 68: HIV/AIDS - p. III-1-37 91. Chapter 69: Shock and Sepsis - p. III-2-41 92. Infection-Related Death: Organ System Infection - p. III-2-47 93. Chapter 70: Bronchopneumonia - p. III-2-47 94. Chapter 71: Infective Endocarditis - p. III-2-51 95. Chapter 72: Clostridium difficile Enterocolitis - p. III-2-55 96. Chapter 73: Viral Hepatitis - p. III-2-59 97. Chapter 74: Urosepsis - p. III-2-63 98. SECTION 3: Neoplasia-Associated Death - p. III-2-67 99. Chapter 75: Neoplasia-Associated Death - p. III-2-67 100. Chapter 76: Death Due to Paraneoplastic Effect - p. III-3-73 101. SECTION 4: Other Common Hospital Death - p. III-3-77 102. Chapter 77: Chronic Obstructive Pulmonary Disease - p. III-3-77 103. Chapter 78: Ventilator Dependent Respiratory Failure - p. III-4-81 104. Chapter 79: Chronic Liver Failure - p. III-4-85 105. Chapter 80: Chronic Renal Failure - p. III-4-91 106. Chapter 81: Dementia and Neurodegenerative Disease - p. III-4-99 107. INDEX - p. III-4-103

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Descripcion
Descripción

The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today’s students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.

  • Clearly written format incorporates rich illustrations, diagrams, and charts.
  • Uses real examples to illustrate key cell biology concepts.
  • Includes beneficial cell physiology coverage.
  • Clinically oriented text relates cell biology to pathophysiology and medicine.
  • Takes a mechanistic approach to molecular processes.
  • Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing.
  • Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation.
  • Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing.
  • Includes hundreds of new and updated diagrams and micrographs, plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail.

1. SECTION 1: Introduction - p. xiii 2. Chapter 1: History of Autopsy - p. xiii 3. Chapter 2: Autopsy Safety - p. I-1-5 4. SECTION 2: Autopsy Performance: External Examination - p. I-1-7 5. Chapter 3: Medical Intervention - p. I-1-7 6. Chapter 4: Postmortem Changes and External Examination - p. I-2-11 7. Autopsy Performance: Internal Examination - p. I-2-15 8. Chapter 5: Body Cavities - p. I-2-15 9. Chapter 6: Cardiovascular System - p. I-2-19 10. Chapter 7: Respiratory System - p. I-2-23 11. Chapter 8: Hematopoietic System - p. I-2-27 12. Chapter 9: Gastrointestinal System - p. I-2-33 13. Chapter 10: Hepatobiliary System - p. I-2-41 14. Chapter 11: Genitourinary System - p. I-2-47 15. Chapter 12: Endocrine System - p. I-2-53 16. Chapter 13: Central Nervous System - p. I-2-59 17. Chapter 14: Peripheral Nervous System - p. I-2-65 18. Chapter 15: Integumentary System - p. I-2-69 19. Chapter 16: Oral Cavity - p. I-2-73 20. Chapter 17: Medical Devices - p. I-2-77 21. Autopsy Performance: Laboratory Testing - p. I-2-81 22. Chapter 18: Chemistry - p. I-2-81 23. Chapter 19: Microbiology - p. I-2-83 24. Chapter 20: Cytology - p. I-2-87 25. Autopsy Performance: Postmortem Imaging - p. I-2-93 26. Chapter 21: Postmortem Radiography and Virtual Autopsy - p. I-2-93 27. SECTION 3: Autopsy Consent and Reporting: Autopsy Consent - p. I-2-99 28. Chapter 22: Consent Process and Legal Considerations - p. I-2-99 29. Autopsy Consent and Reporting: Autopsy Reporting - p. I-3-101 30. Chapter 23: Death Certificate - p. I-3-101 31. Chapter 24: Autopsy Report - p. I-3-105 32. Chapter 25: Presenting Autopsy Findings - p. I-3-107 33. PART II: Organ System Approach to Autopsy - p. I-3-109 34. SECTION 1: Sudden and Unexpected Death: Cardiovascular - p. I-3-109 35. Chapter 26: Pulmonary Thromboembolism - p. I-3-109 36. Chapter 27: Acute Myocardial Infarction - p. II-1-3 37. Chapter 28: Cardiomyopathy - p. II-1-7 38. Chapter 29: Myocarditis - p. II-1-11 39. Chapter 30: Cardiac Conduction System - p. II-1-17 40. Chapter 31: Aortic Dissection - p. II-1-23 41. Chapter 32: Abdominal Aortic Aneurysm - p. II-1-29 42. Sudden and Unexpected Death: Respiratory - p. II-1-31 43. Chapter 33: Pulmonary Edema - p. II-1-31 44. Chapter 34: Pulmonary Hemorrhage - p. II-1-35 45. Chapter 35: Tension Pneumothorax - p. II-1-39 46. Sudden and Unexpected Death: Gastrointestinal - p. II-1-43 47. Chapter 36: Upper Gastrointestinal Hemorrhage - p. II-1-43 48. Chapter 37: Lower Gastrointestinal Hemorrhage - p. II-1-47 49. Chapter 38: Intestinal Ischemia - p. II-1-51 50. Sudden and Unexpected Death: Hepatobiliary - p. II-1-55 51. Chapter 39: Hepatic Hemorrhage - p. II-1-55 52. Chapter 40: Hemorrhagic Pancreatitis - p. II-1-59 53. Chapter 41: Acute Liver Failure - p. II-1-63 54. Sudden and Unexpected Death: Genitourinary - p. II-1-67 55. Chapter 42: Pregnancy Complications - p. II-1-67 56. Chapter 43: Acute Renal Failure - p. II-1-73 57. Sudden and Unexpected Death: Endocrine - p. II-1-83 58. Chapter 44: Adrenal Insufficiency - p. II-1-83 59. Chapter 45: Adrenocortical Excess - p. II-1-87 60. Sudden and Unexpected Death: CNS - p. II-1-91 61. Chapter 46: Seizure Disorders - p. II-1-91 62. Chapter 47: Subdural Hemorrhage - p. II-1-95 63. Chapter 48: Subarachnoid Hemorrhage - p. II-1-99 64. Chapter 49: Stroke - p. II-1-103 65. SECTION 2: Postoperative/Post-Interventional Death: Iatrogenic - p. II-1-109 66. Chapter 50: Therapeutic Complications - p. II-1-109 67. Postoperative/Post-Interventional Death: Cardiovascular - p. II-2-113 68. Chapter 51: Coronary Artery Bypass Grafting - p. II-2-113 69. Chapter 52: Coronary Artery Stenting - p. II-2-117 70. Chapter 53: Valve Replacement (Including Transcatheter) - p. II-2-121 71. Chapter 54: Ventricular Assist Devices - p. II-2-127 72. Chapter 55: Thoracic Aortic Aneurysm Repair - p. II-2-131 73. Postoperative/Post-Interventional Death: Gastrointestinal and Hepatobiliary - p. II-2-137 74. Chapter 56: Pancreas Resection - p. II-2-137 75. Chapter 57: Gastrectomy and Esophagectomy - p. II-2-141 76. Chapter 58: Bariatric Surgery - p. II-2-145 77. Postoperative/Post-Interventional Death: CNS - p. II-2-149 78. Chapter 59: Central Nervous System Tumors - p. II-2-149 79. Chapter 60: Cerebral Aneurysm and Vascular Malformation - p. II-2-155 80. PART III: Disease Process Approach to Autopsy - p. II-2-161 81. SECTION 1: Transplantation - p. II-2-161 82. Chapter 61: Heart Transplant - p. II-2-161 83. Chapter 62: Lung Transplant - p. III-1-7 84. Chapter 63: Kidney Transplant - p. III-1-11 85. Chapter 64: Liver Transplant - p. III-1-21 86. Chapter 65: Pancreas Transplant - p. III-1-27 87. Chapter 66: Bone Marrow Transplant - p. III-1-31 88. Chapter 67: Deceased Donor Autopsy - p. III-1-35 89. SECTION 2: Infection-Related Death: Systemic Infection/Sepsis Overview - p. III-1-37 90. Chapter 68: HIV/AIDS - p. III-1-37 91. Chapter 69: Shock and Sepsis - p. III-2-41 92. Infection-Related Death: Organ System Infection - p. III-2-47 93. Chapter 70: Bronchopneumonia - p. III-2-47 94. Chapter 71: Infective Endocarditis - p. III-2-51 95. Chapter 72: Clostridium difficile Enterocolitis - p. III-2-55 96. Chapter 73: Viral Hepatitis - p. III-2-59 97. Chapter 74: Urosepsis - p. III-2-63 98. SECTION 3: Neoplasia-Associated Death - p. III-2-67 99. Chapter 75: Neoplasia-Associated Death - p. III-2-67 100. Chapter 76: Death Due to Paraneoplastic Effect - p. III-3-73 101. SECTION 4: Other Common Hospital Death - p. III-3-77 102. Chapter 77: Chronic Obstructive Pulmonary Disease - p. III-3-77 103. Chapter 78: Ventilator Dependent Respiratory Failure - p. III-4-81 104. Chapter 79: Chronic Liver Failure - p. III-4-85 105. Chapter 80: Chronic Renal Failure - p. III-4-91 106. Chapter 81: Dementia and Neurodegenerative Disease - p. III-4-99 107. INDEX - p. III-4-103

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