Cellular, Molecular and Environmental Contribution in Cardiac Remodeling: From Lab Bench to Clinical Perspective consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. It extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise and more.
This book provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, and its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed.
1. Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling: From Lab Bench Work to Its Clinical Perspective - p. iii 2. Cover - p. iii 3. Title Page - p. iii 4. Copyright Page - p. iv 5. Table of Contents - p. iv 6. Preface - p. ix 7. Chapter 1 Cardiac remodeling - p. 1 8. Chapter 2 Physiological cardiac modeling - p. 21 9. Chapter 3 Prognostic elements of unfavorable cardiac remodeling - p. 31 10. Chapter 4 Neurohormones in cardiac remodeling and function - p. 51 11. Chapter 5 Cardiokines and cardiac remodeling - p. 71 12. Chapter 6 Comparative effects of fatty acid and glucose in cardiac remodeling - p. 89 13. Chapter 7 Vitamins, minerals, and nutraceuticals - p. 101 14. Chapter 8 Junctional adhesion molecules - p. 113 15. Chapter 9 Composition and function of ion channels and their effects on cardiac remodeling - p. 121 16. Chapter 10 Notch signaling molecules - p. 151 17. Chapter 11 Neuregulin-1 - p. 163 18. Chapter 12 Does endoplasmic reticulum stress break the heart? - p. 171 19. Chapter 13 Role of pattern recognition receptors in cardiac remodeling - p. 185 20. Chapter 14 Myocardial contractile proteins - p. 203 21. Chapter 15 Growth and proliferation of cardiomyocytes - p. 213 22. Chapter 16 Cardiac endothelial cells and their cross-talks with neighboring cells in cardiac remodeling - p. 227 23. Chapter 17 Pathophysiology of cardiac fibroblasts and impacts on the severity of the cardiac disease - p. 239 24. Chapter 18 Involvement of cardiac stem cells in cardiac remodeling or myocardial regeneration - p. 253 25. Chapter 19 Cardiac pericytes and cardiac remodeling - p. 267 26. Chapter 20 Macrophages in the remodeling of diseased heart - p. 277 27. Chapter 21 Inflammatory role of neutrophils in cardiac remodeling - p. 289 28. Chapter 22 Extracellular vesicle in cardiac remodeling - p. 301 29. Chapter 23 Long noncoding RNAs and miRNAs - p. 313 30. Index - p. 327
Cellular, Molecular and Environmental Contribution in Cardiac Remodeling: From Lab Bench to Clinical Perspective consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. It extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise and more.
This book provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, and its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed.
1. Cellular, Molecular, and Environmental Contribution in Cardiac Remodeling: From Lab Bench Work to Its Clinical Perspective - p. iii 2. Cover - p. iii 3. Title Page - p. iii 4. Copyright Page - p. iv 5. Table of Contents - p. iv 6. Preface - p. ix 7. Chapter 1 Cardiac remodeling - p. 1 8. Chapter 2 Physiological cardiac modeling - p. 21 9. Chapter 3 Prognostic elements of unfavorable cardiac remodeling - p. 31 10. Chapter 4 Neurohormones in cardiac remodeling and function - p. 51 11. Chapter 5 Cardiokines and cardiac remodeling - p. 71 12. Chapter 6 Comparative effects of fatty acid and glucose in cardiac remodeling - p. 89 13. Chapter 7 Vitamins, minerals, and nutraceuticals - p. 101 14. Chapter 8 Junctional adhesion molecules - p. 113 15. Chapter 9 Composition and function of ion channels and their effects on cardiac remodeling - p. 121 16. Chapter 10 Notch signaling molecules - p. 151 17. Chapter 11 Neuregulin-1 - p. 163 18. Chapter 12 Does endoplasmic reticulum stress break the heart? - p. 171 19. Chapter 13 Role of pattern recognition receptors in cardiac remodeling - p. 185 20. Chapter 14 Myocardial contractile proteins - p. 203 21. Chapter 15 Growth and proliferation of cardiomyocytes - p. 213 22. Chapter 16 Cardiac endothelial cells and their cross-talks with neighboring cells in cardiac remodeling - p. 227 23. Chapter 17 Pathophysiology of cardiac fibroblasts and impacts on the severity of the cardiac disease - p. 239 24. Chapter 18 Involvement of cardiac stem cells in cardiac remodeling or myocardial regeneration - p. 253 25. Chapter 19 Cardiac pericytes and cardiac remodeling - p. 267 26. Chapter 20 Macrophages in the remodeling of diseased heart - p. 277 27. Chapter 21 Inflammatory role of neutrophils in cardiac remodeling - p. 289 28. Chapter 22 Extracellular vesicle in cardiac remodeling - p. 301 29. Chapter 23 Long noncoding RNAs and miRNAs - p. 313 30. Index - p. 327
