Chordomas and Chondrosarcomas of the Skull Base and Spine, Second Edition, is a major reference and guide for neurosurgeons, medical oncologists, neuroscientists, orthopedic surgeons, head and neck surgeons and radiation oncologists that treat patients and research chordomas and chondrosarcomas of the axial skeleton.
This book is the unique result of the collaboration of multidisciplinary specialists from a wide variety of fields (neurological sciences, medical oncology, molecular biology, orthopedics and radiation oncology), offering the most relevant information about chordomas and chondrosarcomas of the axial skeleton from each of these fields condensed into one single volume.
It contains new medical knowledge and scientific advances regarding the treatment of these types of tumors. Additionally, the book includes chapters written by the Chordoma Foundation and Sarcoma Foundation of America, providing the most valuable information and support for patients and their relatives.
1. Chordomas and Chondrosarcomas of the Skull Base and Spine - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. List of Contributors - p. Page v 8. Foreword - p. Page viii 9. Preface - p. Page ix 10. List of Illustrations - p. Page x 11. List of Tables - p. Page xi 12. Chapter 1 : Embryology of the Skull Base and Vertebral Column - p. Page xi 13. Chapter 2 : Pathology of Chordoma and Chondrosarcoma of the Axial Skeleton - p. Page 9 14. Chapter 3 : Molecular Drivers in Chordoma - p. Page 21 15. Chapter 4 : Molecular Drivers in Chondrosarcoma - p. Page 29 16. Chapter 5 : Demographics, Presentation, and Diagnosis - p. Page 41 17. Chapter 6 : Differential Diagnosis of Clival and Spinal Tumors - p. Page 51 18. Chapter 7 : Imaging Cranial Base Chordoma and Chondrosarcoma - p. Page 62 19. Chapter 8 : Imaging Chordoma and Chondrosarcoma of the Vertebrae and Sacrum - p. Page 78 20. Chapter 9 : Surgical Anatomy of the Skull Base - p. Page 84 21. Chapter 10 : Skull Base Tumors: Surgical Considerations - p. Page 106 22. Chapter 11 : Midline Subfrontal Approaches: The Transbasal Approach and Extended Modifications to Access the Clivus - p. Page 129 23. Chapter 12 : The Endoscopic Endonasal Approach to Chordomas and Chondrosarcomas - p. Page 140 24. Chapter 13 : Transoral Approaches to Midline Skull Base Tumors - p. Page 149 25. Chapter 14 : Chordomas and Chondrosarcomas of the Skull Base: Anterolateral Approaches - p. Page 158 26. Chapter 15 : Lateral Approaches - p. Page 169 27. Chapter 16 : Subtemporal–Preauricular Approach to the Infratemporal Fossa - p. Page 181 28. Chapter 17 : Chordomas and Chondrosarcomas of the Skull Base: Transpetrosal Approaches - p. Page 195 29. Chapter 18 : Chordomas and Chondrosarcomas of the Skull Base: Retrosigmoid Approaches - p. Page 215 30. Chapter 19 : The Extreme Lateral Approach for Chordomas and Chondrosarcomas of the Craniovertebral Junction - p. Page 220 31. Chapter 20 : Staged Approaches for Large Skull Base Chordomas and Chondrosarcomas - p. Page 229 32. Chapter 21 : Cerebral Revascularization for Skull Base Tumors - p. Page 240 33. Chapter 22 : Skull Base Reconstruction Following Resection of Skull Base Chordomas and Chondrosarcomas - p. Page 257 34. Chapter 23 : Stabilization of the Craniocervical Junction Following Resection of Chordomas and Chondrosarcomas of the Skull Base and Spine - p. Page 269 35. Chapter 24 : Chordomas and Chondrosarcomas of the Spine: Preoperative Planning, Surgical Strategies, and Complications Avoidance - p. Page 278 36. Chapter 25 : Surgical Management of Chordomas and Chondrosarcomas of the Cervical Spine - p. Page 291 37. Chapter 26 : Surgical Management of the Chordomas and Chondrosarcomas of the Thoracic Spine - p. Page 299 38. Chapter 27 : Surgical Management of Chordomas and Chondrosarcomas of the Lumbar Spine - p. Page 307 39. Chapter 28 : Anatomical Considerations for Resection of Chordomas and Chondrosarcoma of the Sacrum - p. Page 313 40. Chapter 29 : Surgical Treatment of Sacral Chordoma - p. Page 323 41. Chapter 30 : Fractionated Photon Radiation Therapy for Skull Base Chordomas and Chondrosarcomas - p. Page 332 42. Chapter 31 : Stereotactic Radiosurgery for Skull Base Chordomas and Chondrosarcomas - p. Page 338 43. Chapter 32 : Proton Therapy for Skull Base Chordomas and Chondrosarcomas - p. Page 344 44. Chapter 33 : Photon Irradiation for Spinal Chordomas and Chondrosarcomas - p. Page 353 45. Chapter 34 : Proton Therapy for Spinal Chordomas and Chondrosarcomas - p. Page 357 46. Chapter 35 : Heavy Ion Radiation for Chordomas and Chondrosarcomas - p. Page 367 47. Chapter 36 : Chordomas and Chondrosarcomas in Children - p. Page 380 48. Chapter 37 : Recurrent Skull Base Chordomas: Role of Surgery - p. Page 391 49. Chapter 38 : Systemic Therapies for Locally Recurrent or Metastatic Disease - p. Page 398 50. Chapter 39 : Chordomas and Chondrosarcomas of the Axial Skeleton: Emerging Therapies and Future Directions - p. Page 409 51. Chapter 40 : Prognosis, Survival, and Surveillance - p. Page 418 52. Chapter 41 : The Chordoma Foundation - p. Page 426 53. Chapter 42 : Sarcoma Patient Advocacy: Hope and Help - p. Page 442 54. Index - p. Page 447
Chordomas and Chondrosarcomas of the Skull Base and Spine, Second Edition, is a major reference and guide for neurosurgeons, medical oncologists, neuroscientists, orthopedic surgeons, head and neck surgeons and radiation oncologists that treat patients and research chordomas and chondrosarcomas of the axial skeleton.
This book is the unique result of the collaboration of multidisciplinary specialists from a wide variety of fields (neurological sciences, medical oncology, molecular biology, orthopedics and radiation oncology), offering the most relevant information about chordomas and chondrosarcomas of the axial skeleton from each of these fields condensed into one single volume.
It contains new medical knowledge and scientific advances regarding the treatment of these types of tumors. Additionally, the book includes chapters written by the Chordoma Foundation and Sarcoma Foundation of America, providing the most valuable information and support for patients and their relatives.
1. Chordomas and Chondrosarcomas of the Skull Base and Spine - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. List of Contributors - p. Page v 8. Foreword - p. Page viii 9. Preface - p. Page ix 10. List of Illustrations - p. Page x 11. List of Tables - p. Page xi 12. Chapter 1 : Embryology of the Skull Base and Vertebral Column - p. Page xi 13. Chapter 2 : Pathology of Chordoma and Chondrosarcoma of the Axial Skeleton - p. Page 9 14. Chapter 3 : Molecular Drivers in Chordoma - p. Page 21 15. Chapter 4 : Molecular Drivers in Chondrosarcoma - p. Page 29 16. Chapter 5 : Demographics, Presentation, and Diagnosis - p. Page 41 17. Chapter 6 : Differential Diagnosis of Clival and Spinal Tumors - p. Page 51 18. Chapter 7 : Imaging Cranial Base Chordoma and Chondrosarcoma - p. Page 62 19. Chapter 8 : Imaging Chordoma and Chondrosarcoma of the Vertebrae and Sacrum - p. Page 78 20. Chapter 9 : Surgical Anatomy of the Skull Base - p. Page 84 21. Chapter 10 : Skull Base Tumors: Surgical Considerations - p. Page 106 22. Chapter 11 : Midline Subfrontal Approaches: The Transbasal Approach and Extended Modifications to Access the Clivus - p. Page 129 23. Chapter 12 : The Endoscopic Endonasal Approach to Chordomas and Chondrosarcomas - p. Page 140 24. Chapter 13 : Transoral Approaches to Midline Skull Base Tumors - p. Page 149 25. Chapter 14 : Chordomas and Chondrosarcomas of the Skull Base: Anterolateral Approaches - p. Page 158 26. Chapter 15 : Lateral Approaches - p. Page 169 27. Chapter 16 : Subtemporal–Preauricular Approach to the Infratemporal Fossa - p. Page 181 28. Chapter 17 : Chordomas and Chondrosarcomas of the Skull Base: Transpetrosal Approaches - p. Page 195 29. Chapter 18 : Chordomas and Chondrosarcomas of the Skull Base: Retrosigmoid Approaches - p. Page 215 30. Chapter 19 : The Extreme Lateral Approach for Chordomas and Chondrosarcomas of the Craniovertebral Junction - p. Page 220 31. Chapter 20 : Staged Approaches for Large Skull Base Chordomas and Chondrosarcomas - p. Page 229 32. Chapter 21 : Cerebral Revascularization for Skull Base Tumors - p. Page 240 33. Chapter 22 : Skull Base Reconstruction Following Resection of Skull Base Chordomas and Chondrosarcomas - p. Page 257 34. Chapter 23 : Stabilization of the Craniocervical Junction Following Resection of Chordomas and Chondrosarcomas of the Skull Base and Spine - p. Page 269 35. Chapter 24 : Chordomas and Chondrosarcomas of the Spine: Preoperative Planning, Surgical Strategies, and Complications Avoidance - p. Page 278 36. Chapter 25 : Surgical Management of Chordomas and Chondrosarcomas of the Cervical Spine - p. Page 291 37. Chapter 26 : Surgical Management of the Chordomas and Chondrosarcomas of the Thoracic Spine - p. Page 299 38. Chapter 27 : Surgical Management of Chordomas and Chondrosarcomas of the Lumbar Spine - p. Page 307 39. Chapter 28 : Anatomical Considerations for Resection of Chordomas and Chondrosarcoma of the Sacrum - p. Page 313 40. Chapter 29 : Surgical Treatment of Sacral Chordoma - p. Page 323 41. Chapter 30 : Fractionated Photon Radiation Therapy for Skull Base Chordomas and Chondrosarcomas - p. Page 332 42. Chapter 31 : Stereotactic Radiosurgery for Skull Base Chordomas and Chondrosarcomas - p. Page 338 43. Chapter 32 : Proton Therapy for Skull Base Chordomas and Chondrosarcomas - p. Page 344 44. Chapter 33 : Photon Irradiation for Spinal Chordomas and Chondrosarcomas - p. Page 353 45. Chapter 34 : Proton Therapy for Spinal Chordomas and Chondrosarcomas - p. Page 357 46. Chapter 35 : Heavy Ion Radiation for Chordomas and Chondrosarcomas - p. Page 367 47. Chapter 36 : Chordomas and Chondrosarcomas in Children - p. Page 380 48. Chapter 37 : Recurrent Skull Base Chordomas: Role of Surgery - p. Page 391 49. Chapter 38 : Systemic Therapies for Locally Recurrent or Metastatic Disease - p. Page 398 50. Chapter 39 : Chordomas and Chondrosarcomas of the Axial Skeleton: Emerging Therapies and Future Directions - p. Page 409 51. Chapter 40 : Prognosis, Survival, and Surveillance - p. Page 418 52. Chapter 41 : The Chordoma Foundation - p. Page 426 53. Chapter 42 : Sarcoma Patient Advocacy: Hope and Help - p. Page 442 54. Index - p. Page 447
