Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. ix 6. Preface - p. ix 7. Chapter One: Targeting Chromatin Remodeling in Inflammation and Fibrosis - p. xvi 8. Chapter Two: HMGB1 Protein: A Therapeutic Target Inside and Outside the Cell - p. 36 9. Chapter Three: Targeting IKK and NF-κB for Therapy - p. 76 10. Chapter Four: NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases - p. 115 11. Chapter Five: The Functional Stability of FOXP3 and RORγt in Treg and Th17 and Their Therapeutic Applications - p. 154 12. Chapter Six: The Complex Role of the ZNF224 Transcription Factor in Cancer - p. 189 13. Chapter Seven: Transcription Factors in Breast Cancer—Lessons From Recent Genomic Analyses and Therapeutic Implications - p. 222 14. Chapter Eight: Transcription Factors as a Target for Vaccination Against Ticks and Mites - p. 273 15. Chapter Nine: Elucidating the Mutational Landscape in Hepatocyte Nuclear Factor 1β (HNF1B) by Computational Approach - p. 282 16. Author Index - p. 307 17. Subject Index - p. 361
Chromatin Proteins and Transcription Factors as Therapeutic Targets, the latest volume in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. ix 6. Preface - p. ix 7. Chapter One: Targeting Chromatin Remodeling in Inflammation and Fibrosis - p. xvi 8. Chapter Two: HMGB1 Protein: A Therapeutic Target Inside and Outside the Cell - p. 36 9. Chapter Three: Targeting IKK and NF-κB for Therapy - p. 76 10. Chapter Four: NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases - p. 115 11. Chapter Five: The Functional Stability of FOXP3 and RORγt in Treg and Th17 and Their Therapeutic Applications - p. 154 12. Chapter Six: The Complex Role of the ZNF224 Transcription Factor in Cancer - p. 189 13. Chapter Seven: Transcription Factors in Breast Cancer—Lessons From Recent Genomic Analyses and Therapeutic Implications - p. 222 14. Chapter Eight: Transcription Factors as a Target for Vaccination Against Ticks and Mites - p. 273 15. Chapter Nine: Elucidating the Mutational Landscape in Hepatocyte Nuclear Factor 1β (HNF1B) by Computational Approach - p. 282 16. Author Index - p. 307 17. Subject Index - p. 361