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This issue of Neurologic Clinics, guest edited by Dr. Phyllis C. Zee, with consulting editor Randolph W. Evans, will focus on Circadian Rhythm Disorders. Topics include, but are not limited to, Circadian biology, Genetic basis of circadian rhythms, Implication of circadian rhythm misalignment on sleep and health, Assessment of circadian rhythms, Circadian Rhythm sleep-wake phase disorders, Irregular sleep-wake rhythm sleep –wake disorder, Non-24 hour sleep-wake rhythm disorder, Shift Work Sleep Disorder, Challenging cases, and Future of circadian and sleep medicine.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. viii 7. Preface - p. ix 8. Circadian Neurobiology and the Physiologic Regulation of Sleep and Wakefulness - p. 475 9. Genetics of Circadian Rhythms - p. 487 10. Assessment of Circadian Rhythms - p. 505 11. Circadian Rhythm Sleep-Wake Phase Disorders - p. 527 12. Non–24-hour Sleep-Wake Rhythm Disorder - p. 545 13. Irregular Sleep-Wake Rhythm Disorder - p. 553 14. Shift Work Disorder - p. 563 15. Challenging Circadian Rhythm Disorder Cases - p. 579 16. Circadian Rhythms: Implications for Health and Disease - p. 601 17. Sleep and Circadian Medicine: Time of Day in the Neurologic Clinic - p. 615

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This issue of Neurologic Clinics, guest edited by Dr. Phyllis C. Zee, with consulting editor Randolph W. Evans, will focus on Circadian Rhythm Disorders. Topics include, but are not limited to, Circadian biology, Genetic basis of circadian rhythms, Implication of circadian rhythm misalignment on sleep and health, Assessment of circadian rhythms, Circadian Rhythm sleep-wake phase disorders, Irregular sleep-wake rhythm sleep –wake disorder, Non-24 hour sleep-wake rhythm disorder, Shift Work Sleep Disorder, Challenging cases, and Future of circadian and sleep medicine.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. viii 7. Preface - p. ix 8. Circadian Neurobiology and the Physiologic Regulation of Sleep and Wakefulness - p. 475 9. Genetics of Circadian Rhythms - p. 487 10. Assessment of Circadian Rhythms - p. 505 11. Circadian Rhythm Sleep-Wake Phase Disorders - p. 527 12. Non–24-hour Sleep-Wake Rhythm Disorder - p. 545 13. Irregular Sleep-Wake Rhythm Disorder - p. 553 14. Shift Work Disorder - p. 563 15. Challenging Circadian Rhythm Disorder Cases - p. 579 16. Circadian Rhythms: Implications for Health and Disease - p. 601 17. Sleep and Circadian Medicine: Time of Day in the Neurologic Clinic - p. 615

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