Clinical Chemistry considers what happens to the body's chemistry when affected by disease. It provides introductory coverage of the scientific basis for biochemistry tests routinely used in medicine - including tests for the assessment of organ function, diagnosis and monitoring disease activity and therapy efficacy. Each topic area begins with a concise description of the underlying physiological and biochemical principles and then applies them to patient investigation and management. The regular use of case histories helps further emphasise clinical relevance and chapter key points, as well as provide a useful starting point for examination revision. The clear and engaging writing style appreciated by generations of readers has been retained in this tenth edition, while the content has been thoroughly updated throughout. The approach and scope of this trusted text makes it ideal for integrated medical curricula, for medical training and for students and practitioners of clinical and biomedical science. The complementary eBook version, including additional cases and self-assessment material, completes this superb learning package.
1. 1. An introduction to biochemistry and cell biology - p. 1 2. 2. Biochemical investigations in clinical medicine - p. 11 3. 3. Water, sodium and potassium - p. 24 4. 4. Hydrogen ion homoeostasis and blood gases - p. 53 5. 5. The kidneys - p. 75 6. 6. The liver - p. 99 7. 7. The gastrointestinal tract - p. 120 8. 8. Clinical nutrition - p. 133 9. 9. The hypothalamus and the pituitary gland - p. 149 10. 10. The adrenal glands - p. 168 11. 11. The thyroid gland - p. 186 12. 12. The gonads - p. 200 13. 13. Disorders of carbohydrate metabolism - p. 213 14. 14. Calcium, phosphate and magnesium - p. 240 15. 15. Bones and joints - p. 257 16. 16. Plasma proteins and enzymes - p. 269 17. 17. Lipids, lipoproteins and cardiovascular disease - p. 285 18. 18. Muscles, nerves and psychiatric disorders - p. 306 19. 19. Inherited metabolic diseases - p. 315 20. 20. Metabolic aspects of malignant Disease - p. 329 21. 21. Biochemical aspects of therapeutic drug monitoring and toxicology - p. 341 22. 22. Clinical chemistry in children - p. 357 23. Appendix - p. 364 24. Index - p. 366
Clinical Chemistry considers what happens to the body's chemistry when affected by disease. It provides introductory coverage of the scientific basis for biochemistry tests routinely used in medicine - including tests for the assessment of organ function, diagnosis and monitoring disease activity and therapy efficacy. Each topic area begins with a concise description of the underlying physiological and biochemical principles and then applies them to patient investigation and management. The regular use of case histories helps further emphasise clinical relevance and chapter key points, as well as provide a useful starting point for examination revision. The clear and engaging writing style appreciated by generations of readers has been retained in this tenth edition, while the content has been thoroughly updated throughout. The approach and scope of this trusted text makes it ideal for integrated medical curricula, for medical training and for students and practitioners of clinical and biomedical science. The complementary eBook version, including additional cases and self-assessment material, completes this superb learning package.
1. 1. An introduction to biochemistry and cell biology - p. 1 2. 2. Biochemical investigations in clinical medicine - p. 11 3. 3. Water, sodium and potassium - p. 24 4. 4. Hydrogen ion homoeostasis and blood gases - p. 53 5. 5. The kidneys - p. 75 6. 6. The liver - p. 99 7. 7. The gastrointestinal tract - p. 120 8. 8. Clinical nutrition - p. 133 9. 9. The hypothalamus and the pituitary gland - p. 149 10. 10. The adrenal glands - p. 168 11. 11. The thyroid gland - p. 186 12. 12. The gonads - p. 200 13. 13. Disorders of carbohydrate metabolism - p. 213 14. 14. Calcium, phosphate and magnesium - p. 240 15. 15. Bones and joints - p. 257 16. 16. Plasma proteins and enzymes - p. 269 17. 17. Lipids, lipoproteins and cardiovascular disease - p. 285 18. 18. Muscles, nerves and psychiatric disorders - p. 306 19. 19. Inherited metabolic diseases - p. 315 20. 20. Metabolic aspects of malignant Disease - p. 329 21. 21. Biochemical aspects of therapeutic drug monitoring and toxicology - p. 341 22. 22. Clinical chemistry in children - p. 357 23. Appendix - p. 364 24. Index - p. 366
