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This issue of Infectious Disease Clinics of North America, guest edited by Dr. Mark H. Wilcox, is devoted to Clostridium Difficile Infection. Articles in this issue include: Potential sources of C. difficile for human infection; Colonisation versus carriage of C. difficile; Diagnostic pitfalls in C. difficile infection; The epidemiology of C. difficile infection in and outside of healthcare institutions; What makes epidemic C. difficile strains epidemic?: Fact versus fiction; Environmental interventions to control C. difficile infection; The contribution of strains and hosts to outcomes in C. difficile infection; Treatment of C. difficile infection; Faecal microbiota transplantation for the management of C. difficile infection; The morbidity, mortality, and costs associated with C. difficile infection; The potential of probiotics to prevent C. difficile infection; The prospect for vaccines to prevent C. difficile infection; and Predictive value of models of C. difficile infection.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 8 7. Preface - p. 9 8. New Perspectives in Clostridium difficile Disease Pathogenesis - p. 10 9. Colonization Versus Carriage of Clostridium difficile - p. 17 10. Potential Sources of Clostridium difficile in Human Infection - p. 25 11. The Epidemiology of Clostridium difficile Infection Inside and Outside Health Care Institutions - p. 30 12. The Contribution of Strains and Hosts to Outcomes in Clostridium difficile Infection - p. 39 13. Diagnostic Pitfalls in Clostridium difficile Infection - p. 45 14. Environmental Interventions to Control Clostridium difficile - p. 55 15. Treatment of Clostridium difficile Infections - p. 61 16. Fecal Microbiota Transplantation for the Management of Clostridium difficile Infection - p. 71 17. The Morbidity, Mortality, and Costs Associated with Clostridium difficile Infection - p. 77 18. The Potential of Probiotics to Prevent Clostridium difficile Infection - p. 84 19. The Prospect for Vaccines to Prevent Clostridium difficile Infection - p. 89 20. Predictive Values of Models of Clostridium difficile Infection - p. 101 21. Index - p. 110

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This issue of Infectious Disease Clinics of North America, guest edited by Dr. Mark H. Wilcox, is devoted to Clostridium Difficile Infection. Articles in this issue include: Potential sources of C. difficile for human infection; Colonisation versus carriage of C. difficile; Diagnostic pitfalls in C. difficile infection; The epidemiology of C. difficile infection in and outside of healthcare institutions; What makes epidemic C. difficile strains epidemic?: Fact versus fiction; Environmental interventions to control C. difficile infection; The contribution of strains and hosts to outcomes in C. difficile infection; Treatment of C. difficile infection; Faecal microbiota transplantation for the management of C. difficile infection; The morbidity, mortality, and costs associated with C. difficile infection; The potential of probiotics to prevent C. difficile infection; The prospect for vaccines to prevent C. difficile infection; and Predictive value of models of C. difficile infection.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 8 7. Preface - p. 9 8. New Perspectives in Clostridium difficile Disease Pathogenesis - p. 10 9. Colonization Versus Carriage of Clostridium difficile - p. 17 10. Potential Sources of Clostridium difficile in Human Infection - p. 25 11. The Epidemiology of Clostridium difficile Infection Inside and Outside Health Care Institutions - p. 30 12. The Contribution of Strains and Hosts to Outcomes in Clostridium difficile Infection - p. 39 13. Diagnostic Pitfalls in Clostridium difficile Infection - p. 45 14. Environmental Interventions to Control Clostridium difficile - p. 55 15. Treatment of Clostridium difficile Infections - p. 61 16. Fecal Microbiota Transplantation for the Management of Clostridium difficile Infection - p. 71 17. The Morbidity, Mortality, and Costs Associated with Clostridium difficile Infection - p. 77 18. The Potential of Probiotics to Prevent Clostridium difficile Infection - p. 84 19. The Prospect for Vaccines to Prevent Clostridium difficile Infection - p. 89 20. Predictive Values of Models of Clostridium difficile Infection - p. 101 21. Index - p. 110

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