Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions.
The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules.
1. 1 General introduction of coumarin - p. 1 2. 2 Synthesis and reactivity - p. 49 3. 3 Naturally occurring coumarins in the development of commercial drugs - p. 119 4. 4 Multitargeted scaffold in medicinal chemistry: Potential anticancer agents - p. 209 5. 5 Role of coumarins in different infectious diseases - p. 349 6. Abstract - p. 349 7. 1 Infectious diseases: A detailed overview - p. 350 8. 2 Viruses and their role in human disease - p. 354 9. 3 Therapeutic potential and molecular targets of coumarins as antiviral agents - p. 356 10. 4 Coumarin derivatives against RNA viruses - p. 364 11. 5 Coumarin-containing hybrids and their antibacterial activities - p. 407 12. 6 Developments in coumarin-containing derivatives and their anti-tubercular activity - p. 426 13. 7 Fungal infections: Pathogens, pathogenicity, and the potential of coumarins as antifungal agents - p. 445 14. 8 Parasites - p. 466 15. 9 Conclusion - p. 495 16. References - p. 496 17. 6 In the design and development of neurotherapeutics agents - p. 547 18. 7 Development as antiinflammatory and anticoagulant agents - p. 593 19. 8 Potential in antidiabetic and antioxidant therapies - p. 617 20. 9 Coumarin-based metal complexes and polymers - p. 651 21. 10 Recent advances in applications of coumarins: A brief discussion on patents and activities, status, and perspectives - p. 699 22. Glossary of terms - p. 747 23. Index - p. 757
Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions.
The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules.
1. 1 General introduction of coumarin - p. 1 2. 2 Synthesis and reactivity - p. 49 3. 3 Naturally occurring coumarins in the development of commercial drugs - p. 119 4. 4 Multitargeted scaffold in medicinal chemistry: Potential anticancer agents - p. 209 5. 5 Role of coumarins in different infectious diseases - p. 349 6. Abstract - p. 349 7. 1 Infectious diseases: A detailed overview - p. 350 8. 2 Viruses and their role in human disease - p. 354 9. 3 Therapeutic potential and molecular targets of coumarins as antiviral agents - p. 356 10. 4 Coumarin derivatives against RNA viruses - p. 364 11. 5 Coumarin-containing hybrids and their antibacterial activities - p. 407 12. 6 Developments in coumarin-containing derivatives and their anti-tubercular activity - p. 426 13. 7 Fungal infections: Pathogens, pathogenicity, and the potential of coumarins as antifungal agents - p. 445 14. 8 Parasites - p. 466 15. 9 Conclusion - p. 495 16. References - p. 496 17. 6 In the design and development of neurotherapeutics agents - p. 547 18. 7 Development as antiinflammatory and anticoagulant agents - p. 593 19. 8 Potential in antidiabetic and antioxidant therapies - p. 617 20. 9 Coumarin-based metal complexes and polymers - p. 651 21. 10 Recent advances in applications of coumarins: A brief discussion on patents and activities, status, and perspectives - p. 699 22. Glossary of terms - p. 747 23. Index - p. 757
