Trusted by clinicians for more than 75 years, Conn’s Current Therapy presents today’s evidence-based information along with the personal experience and discernment of expert physicians. The 2025 edition is a helpful resource for a wide range of healthcare providers, including primary care physicians, subspecialists, and allied health professionals, providing current treatment information in a concise yet in-depth format. Nearly 350 topics have been carefully reviewed and updated to bring you state-of-the-art content in even the most rapidly changing areas of medicine.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Section 1: Symptomatic Care Pending Diagnosis - p. iii 8. List of Tables - p. iii 9. Chapter 1: Chest Pain - p. iii 10. Chapter 2: Constipation - p. iii 11. Chapter 3: Cough - p. iii 12. Chapter 4: Dizziness and Vertigo - p. iii 13. Chapter 5: Fatigue - p. iii 14. Chapter 6: Fever - p. iii 15. Chapter 7: Gaseousness, Indigestion, Nausea, and Vomiting - p. iii 16. Chapter 8: Hematuria - p. iii 17. Chapter 9: Hiccups - p. iii 18. Chapter 10: Hoarseness and Laryngitis - p. iii 19. Chapter 11: Leg Edema and Venous Stasis - p. iii 20. Chapter 12: Pain - p. iii 21. Chapter 13: Palliative and End-of-Life Care - p. iii 22. Chapter 14: Palpitations - p. g44 23. Chapter 15: Pharyngitis - p. g44 24. Chapter 16: Pruritis - p. g44 25. Chapter 17: Rhinitis - p. g44 26. Chapter 18: Spine Pain - p. g44 27. Chapter 19: Tinnitus - p. g44 28. Section 2: Allergy - p. g44 29. Chapter 20: Allergic Reactions to Insect Stings - p. g44 30. Chapter 21: Anaphylaxis - p. g44 31. Chapter 22: Drug Hypersensitivity Reactions - p. g44 32. Chapter 23: Serum Sickness - p. g44 33. Section 3: Cardiovascular System - p. g44 34. Chapter 24: Acute Myocardial Infarction - p. g44 35. Chapter 25: Angina Pectoris - p. g44 36. Chapter 26: Aortic Disease: Aneurysm and Dissection - p. g96 37. Chapter 27: Atrial Fibrillation - p. g113 38. Chapter 28: Congenital Heart Disease - p. g115 39. Chapter 29: Congestive Heart Failure - p. g121 40. Chapter 30: Heart Block - p. g126 41. Chapter 31: Hypertension - p. g131 42. Chapter 32: Hypertrophic Cardiomyopathy - p. g137 43. Chapter 33: Infective Endocarditis - p. g143 44. Chapter 34: Mitral Valve Prolapse - p. g147 45. Chapter 35: Pericarditis - p. g151 46. Chapter 36: Peripheral Artery Disease - p. g155 47. Chapter 37: Premature Beats - p. g159 48. Chapter 38: Tachycardias - p. g161 49. Chapter 39: Valvular Heart Disease - p. g167 50. Chapter 40: Venous Thrombosis - p. g172 51. Section 4: Digestive System - p. g178 52. Chapter 41: Acute and Chronic Pancreatitis - p. g178 53. Chapter 42: Acute Diarrhea - p. g186 54. Chapter 43: Bleeding Esophageal Varices - p. g192 55. Chapter 44: Calculous Biliary Disease - p. g198 56. Chapter 45: Chronic Diarrhea - p. g203 57. Chapter 46: Cirrhosis - p. g210 58. Chapter 47: Diverticula of the Alimentary Tract - p. g222 59. Chapter 48: Dysphagia and Esophageal Obstruction - p. g226 60. Chapter 49: Gastritis and Peptic Ulcer Disease - p. g232 61. Chapter 50: Gastroesophageal Reflux Disease (GERD) - p. g235 62. Chapter 51: Hemorrhoids, Anal Fissure, and Anorectal Abscess and Fistula - p. g238 63. Chapter 52: Hepatitis A, B, D, and E - p. g242 64. Chapter 53: Hepatitis C - p. g250 65. Chapter 54: Inflammatory Bowel Disease: Crohn’s Disease and Ulcerative Colitis - p. g252 66. Chapter 55: Intestinal Parasites - p. g261 67. Chapter 56: Irritable Bowel Syndrome - p. g276 68. Chapter 57: Malabsorption - p. g279 69. Chapter 58: Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) - p. g285 70. Chapter 59: Pancreatic Cancer - p. g293 71. Chapter 60: Tumors of the Colon and Rectum - p. g296 72. Chapter 61: Tumors of the Stomach - p. g301 73. Section 5: Endocrine and Metabolic Disorders - p. g305 74. Chapter 62: Acromegaly - p. g305 75. Chapter 63: Adrenocortical Insufficiency - p. g311 76. Chapter 64: Cushing’s Syndrome - p. g314 77. Chapter 65: Diabetes Insipidus - p. g320 78. Chapter 66: Diabetes Mellitus in Adults - p. g323 79. Chapter 67: Diabetic Ketoacidosis - p. g337 80. Chapter 68: Gender-Affirming Care - p. g342 81. Chapter 69: Gout and Hyperuricemia - p. g347 82. Chapter 70: Hyperaldosteronism - p. g350 83. Chapter 71: Hyperlipidemia - p. g358 84. Chapter 72: Hyperparathyroidism and Hypoparathyroidism - p. g369 85. Chapter 73: Hyperprolactinemia - p. g377 86. Chapter 74: Hyperthyroidism - p. g384 87. Chapter 75: Hypokalemia and Hyperkalemia - p. g388 88. Chapter 76: Hyponatremia - p. g391 89. Chapter 77: Hypopituitarism - p. g398 90. Chapter 78: Hypothyroidism - p. g402 91. Chapter 79: Obesity in Adults - p. g404 92. Chapter 80: Parenteral Nutrition in Adults - p. g410 93. Chapter 81: Pheochromocytoma - p. g420 94. Chapter 82: Thyroid Cancer - p. g429 95. Chapter 83: Thyroiditis - p. g434 96. Section 6: Hematology - p. g436 97. Chapter 84: Acute Leukemia in Adults - p. g436 98. Chapter 85: Blood Component Therapy and Transfusion Reactions - p. g442 99. Chapter 86: Chronic Leukemias - p. g449 100. Chapter 87: Disseminated Intravascular Coagulation - p. g455 101. Chapter 88: Hemochromatosis - p. g458 102. Chapter 89: Hemolytic Anemias - p. g461 103. Chapter 90: Hemophilia and Related Conditions - p. g467 104. Chapter 91: Hodgkin Disease - p. g475 105. Chapter 92: Iron Deficiency Anemia - p. g478 106. Chapter 93: Megaloblastic Anemias - p. g481 107. Chapter 94: Multiple Myeloma - p. g484 108. Chapter 95: Myelodysplastic Syndromes - p. g489 109. Chapter 96: Lymphoma - p. g493 110. Chapter 97: Platelet-Mediated Bleeding Disorders - p. g503 111. Chapter 98: Polycythemia Vera - p. g507 112. Chapter 99: Porphyrias - p. g511 113. Chapter 100: Sickle Cell Disease - p. g514 114. Chapter 101: Thalassemia - p. g527 115. Chapter 102: Thrombotic Thrombocytopenic Purpura - p. g533 116. Section 7: Head and Neck - p. g537 117. Chapter 103: Dry Eye Syndrome - p. g537 118. Chapter 104: Glaucoma - p. g541 119. Chapter 105: Ménière’s Disease - p. g545 120. Chapter 106: Otitis Externa - p. g549 121. Chapter 107: Otitis Media - p. g551 122. Chapter 108: Red Eye - p. g555 123. Chapter 109: Rhinosinusitis - p. g560 124. Chapter 110: Temporomandibular Disorders - p. g562 125. Chapter 111: Uveitis - p. g565 126. Chapter 112: Vision Rehabilitation - p. g572 127. Section 8: Infectious Diseases - p. g576 128. Chapter 113: Amebiasis - p. g576 129. Chapter 114: Anthrax - p. g581 130. Chapter 115: Babesiosis - p. g584 131. Chapter 116: Bacterial Meningitis - p. g585 132. Chapter 117: Brucellosis - p. g589 133. Chapter 118: Clostridioides Difficile Colitis - p. g593 134. Chapter 119: Cat Scratch Disease - p. g596 135. Chapter 120: Chikungunya - p. g598 136. Chapter 121: Cholera - p. g600 137. Chapter 122: COVID-19 - p. g603 138. Chapter 123: Ebola Virus Disease - p. g607 139. Chapter 124: Foodborne Illnesses - p. g610 140. Chapter 125: Giardiasis - p. g621 141. Chapter 126: Human Immunodeficiency Virus: Treatment and Prevention - p. g624 142. Chapter 127: Infectious Mononucleosis - p. g638 143. Chapter 128: Influenza - p. g639 144. Chapter 129: Leishmaniasis - p. g643 145. Chapter 130: Leprosy - p. g648 146. Chapter 131: Lyme Disease and Post-Treatment Lyme Disease Syndrome - p. g654 147. Chapter 132: Malaria - p. g658 148. Chapter 133: Measles (Rubeola) - p. g669 149. Chapter 134: Methicillin-Resistant Staphylococcus Aureus - p. g672 150. Chapter 135: Mpox - p. g677 151. Chapter 136: Mumps - p. g685 152. Chapter 137: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - p. g686 153. Chapter 138: Necrotizing Skin and Soft-Tissue Infections - p. g689 154. Chapter 139: Osteomyelitis - p. g691 155. Chapter 140: Plague - p. g698 156. Chapter 141: Post-Acute COVID Syndrome - p. g700 157. Chapter 142: Psittacosis - p. g707 158. Chapter 143: Q Fever - p. g708 159. Chapter 144: Rabies - p. g710 160. Chapter 145: Rat-Bite Fever - p. g712 161. Chapter 146: Relapsing Fever - p. g714 162. Chapter 147: Rubella and Congenital Rubella - p. g718 163. Chapter 148: Salmonellosis - p. g720 164. Chapter 149: Sepsis - p. g723 165. Chapter 150: Smallpox - p. g727 166. Chapter 151: Tetanus - p. g731 167. Chapter 152: Tickborne Rickettsial Diseases (Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis) - p. g735 168. Chapter 153: Toxic Shock Syndrome - p. g739 169. Chapter 154: Toxoplasmosis - p. g741 170. Chapter 155: Typhoid Fever - p. g745 171. Chapter 156: Tamilarasu Kadhiravan, MD Varicella (Chickenpox) - p. g747 172. Chapter 157: Viral Meningitis - p. g750 173. Chapter 158: Whooping Cough (Pertussis) - p. g753 174. Chapter 159: Yellow Fever - p. g755 175. Chapter 160: Zika Virus Disease - p. g758 176. Section 9: Neurological System - p. g762 177. Chapter 161: Acute Facial Paralysis - p. g762 178. Chapter 162: Alzheimer’s Disease - p. g765 179. Chapter 163: Central Nervous System Neoplasms - p. g773 180. Chapter 164: Gilles de la Tourette Syndrome - p. g779 181. Chapter 165: Intracerebral Hemorrhage - p. g782 182. Chapter 166: Ischemic Cerebrovascular Disease - p. g789 183. Chapter 167: Migraine - p. g791 184. Chapter 168: Multiple Sclerosis - p. g797 185. Chapter 169: Myasthenia Gravis - p. g806 186. Chapter 170: Neurofibromatosis (Type 1) - p. g810 187. Chapter 171: Nonmigraine Headache - p. g814 188. Chapter 172: Optic Neuritis - p. g818 189. Chapter 173: Parkinson Disease - p. g819 190. Chapter 174: Rehabilitation of the Stroke Patient - p. g826 191. Chapter 175: Seizures and Epilepsy in Adolescents and Adults - p. g830 192. Chapter 176: Sleep Disorders - p. g840 193. Chapter 177: Sports-Related Head Injuries - p. g855 194. Chapter 178: Targeted Temperature Management (Therapeutic Hypothermia) - p. g860 195. Chapter 179: Trigeminal Neuralgia - p. g862 196. Section 10: Psychiatric Disorders - p. g864 197. Chapter 180: Alcohol Use Disorder - p. g864 198. Chapter 181: Autism Spectrum Disorder - p. g869 199. Chapter 182: Delirium - p. g873 200. Chapter 183: Depressive (Major) and Bipolar Disorder - p. g876 201. Chapter 184: Drug Use Disorders - p. g882 202. Chapter 185: Eating Disorders - p. g888 203. Chapter 186: Generalized Anxiety Disorder - p. g893 204. Chapter 187: Obsessive-Compulsive Disorder - p. g896 205. Chapter 188: Panic Disorder - p. g898 206. Chapter 189: Posttraumatic Stress Disorder - p. g901 207. Chapter 190: Schizophrenia - p. g905 208. Section 11: Respiratory System - p. g909 209. Chapter 191: Acute Bronchitis and Other Viral Respiratory Infections - p. g909 210. Chapter 192: Acute Respiratory Failure - p. g913 211. Chapter 193: Asthma in Adolescents and Adults - p. g918 212. Chapter 194: Atelectasis - p. g926 213. Chapter 195: Bacterial Pneumonia - p. g926 214. Chapter 196: Blastomycosis - p. g932 215. Chapter 197: Chronic Obstructive Pulmonary Disease - p. g936 216. Chapter 198: Coccidioidomycosis - p. g943 217. Chapter 199: Cystic Fibrosis - p. g945 218. Chapter 200: Histoplasmosis - p. g950 219. Chapter 201: Hypersensitivity Pneumonitis - p. g954 220. Chapter 202: Legionellosis (Legionnaire’s Disease and Pontiac Fever) - p. g955 221. Chapter 203: Lung Abscess - p. g957 222. Chapter 204: Lung Cancer - p. g959 223. Chapter 205: Obstructive Sleep Apnea - p. g970 224. Chapter 206: Pleural Effusion and Empyema - p. g973 225. Chapter 207: Pneumoconiosis: Asbestosis and Silicosis - p. g980 226. Chapter 208: Pulmonary Hypertension - p. g979 227. Chapter 209: Sarcoidosis - p. g984 228. Chapter 210: Tuberculosis and Other Mycobacterial Diseases - p. g988 229. Chapter 211: Venous Thromboembolism - p. g996 230. Chapter 212: Viral and Mycoplasmal Pneumonias - p. g1008 231. Chapter 213: Viral Respiratory Infections - p. g1013 232. Section 12: Rheumatology and the Musculoskeletal System - p. g1016 233. Chapter 214: Axial Spondyloarthritis - p. g1016 234. Chapter 215: Common Sports Injuries - p. g1020 235. Chapter 216: Connective Tissue Disorders - p. g1031 236. Chapter 217: Fibromyalgia - p. g1035 237. Chapter 218: Juvenile Idiopathic Arthritis - p. g1039 238. Chapter 219: Osteoarthritis - p. g1045 239. Chapter 220: Osteoporosis - p. g1048 240. Chapter 221: Paget’s Disease of Bone - p. g1053 241. Chapter 222: Polymyalgia Rheumatica and Giant Cell Arteritis - p. g1056 242. Chapter 223: Psoriatic Arthritis - p. g1059 243. Chapter 224: Rheumatoid Arthritis - p. g1063 244. Chapter 225: Tendinopathy and Bursitis - p. g1068 245. Section 13: Sexually Transmitted Diseases - p. g1071 246. Chapter 226: Chlamydia Trachomatis - p. g1071 247. Chapter 227: Condylomata Acuminata - p. g1075 248. Chapter 228: Genital Ulcer Disease: Chancroid, Granuloma Inguinale, and Lymphogranuloma - p. g1077 249. Chapter 229: Gonorrhea - p. g1080 250. Chapter 230: Non-Gonococcal Urethritis - p. g1083 251. Chapter 231: Syphilis - p. g1085 252. Section 14: Skin Disease - p. g1088 253. Chapter 232: Acne Vulgaris - p. g1088 254. Chapter 233: Atopic Dermatitis - p. g1092 255. Chapter 234: Autoimmune Bullous Diseases - p. g1096 256. Chapter 235: Bacterial Diseases of the Skin - p. g1100 257. Chapter 236: Contact Dermatitis - p. g1103 258. Chapter 237: Cutaneous T-Cell Lymphomas, Including Mycosis Fungoides and Sézary Syndrome - p. g1106 259. Chapter 238: Cutaneous Vasculitis - p. g1112 260. Chapter 239: Diseases of the Hair - p. g1115 261. Chapter 240: Diseases of the Mouth - p. g1118 262. Chapter 241: Diseases of the Nail - p. g1124 263. Chapter 242: Erythema Multiforme - p. g1127 264. Chapter 243: Fungal Infections of the Skin - p. g1129 265. Chapter 244: Keloids and Hypertrophic Scars - p. g1132 266. Chapter 245: Melanoma - p. g1136 267. Chapter 246: Nevi - p. g1140 268. Chapter 247: Nonmelanoma Cancer of the Skin - p. g1144 269. Chapter 248: Papulosquamous Eruptions - p. g1148 270. Chapter 249: Parasitic Diseases of the Skin - p. g1154 271. Chapter 250: Pigmentary Disorders - p. g1159 272. Chapter 251: Premalignant Skin Lesions - p. g1162 273. Chapter 252: Pressure Injury - p. g1165 274. Chapter 253: Pruritus Ani and Vulvae - p. g1167 275. Chapter 254: Pyoderma Gangrenosum - p. g1171 276. Chapter 255: Rosacea - p. g1174 277. Chapter 256: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis - p. g1175 278. Chapter 257: Sunburn - p. g1177 279. Chapter 258: Urticaria and Angioedema - p. g1179 280. Chapter 259: Venous Ulcers - p. g1181 281. Chapter 260: Viral Diseases of the Skin - p. g1184 282. Chapter 261: Warts (Verrucae) - p. g1190 283. Section 15: Urogenital Tract - p. g1193 284. Chapter 262: Acute Kidney Injury - p. g1193 285. Chapter 263: Chronic Kidney Disease - p. g1198 286. Chapter 264: Malignant Tumors of the Urogenital Tract - p. g1206 287. Chapter 265: Nephrolithiasis - p. g1213 288. Chapter 266: Primary Glomerular Disease - p. g1216 289. Chapter 267: Pyelonephritis - p. g1221 290. Chapter 268: Trauma to the Genitourinary Tract - p. g1224 291. Chapter 269: Urethral Stricture Disease - p. g1227 292. Chapter 270: Urinary Incontinence - p. g1229 293. Section 16: Men’s Health - p. g1231 294. Chapter 271: Benign Prostatic Hyperplasia - p. g1231 295. Chapter 272: Epididymitis and Orchitis - p. g1236 296. Chapter 273: Erectile Dysfunction - p. g1238 297. Chapter 274: Prostate Cancer - p. g1241 298. Chapter 275: Prostatitis - p. g1246 299. Chapter 276: Urinary Tract Infections in the Male - p. g1248 300. Section 17: Women’s Health - p. g1251 301. Chapter 277: Abnormal Uterine Bleeding - p. g1251 302. Chapter 278: Amenorrhea - p. g1254 303. Chapter 279: Bacterial Infections of the Urinary Tract in Women - p. g1258 304. Chapter 280: Benign Breast Disease - p. g1260 305. Chapter 281: Breast Cancer - p. g1264 306. Chapter 282: Cancer of the Endometrium - p. g1267 307. Chapter 283: Cancer of the Uterine Cervix - p. g1270 308. Chapter 284: Contraception - p. g1274 309. Chapter 285: Dysmenorrhea - p. g1278 310. Chapter 286: Endometriosis - p. g1280 311. Chapter 287: Female Sexual Concerns - p. g1283 312. Chapter 288: Infertility - p. g1287 313. Chapter 289: Menopause - p. g1289 314. Chapter 290: Ovarian Cancer - p. g1293 315. Chapter 291: Pelvic Inflammatory Disease - p. g1296 316. Chapter 292: Premenstrual Dysphoric Disorder - p. g1298 317. Chapter 293: Uterine Leiomyoma - p. g1301 318. Chapter 294: Vulvar Neoplasia - p. g1305 319. Chapter 295: Vulvovaginitis - p. g1307 320. Section 18: Pregnancy and Antepartum Care - p. g1311 321. Chapter 296: Antepartum Care - p. g1311 322. Chapter 297: Ectopic Pregnancy - p. g1320 323. Chapter 298: Hypertensive Disorders in Pregnancy - p. g1323 324. Chapter 299: Postpartum Care - p. g1328 325. Chapter 300: Postpartum Depression - p. g1329 326. Chapter 301: Vaginal Bleeding in Pregnancy - p. g1332 327. Section 19: Children’s Health - p. g1335 328. Chapter 302: Acute Leukemia in Children - p. g1335 329. Chapter 303: Adolescent Health - p. g1344 330. Chapter 304: Asthma in Children - p. g1348 331. Chapter 305: Attention-Deficit/Hyperactivity Disorder - p. g1355 332. Chapter 306: Bronchiolitis - p. g1364 333. Chapter 307: Diabetes Mellitus in Children - p. g1367 334. Chapter 308: Encopresis - p. g1372 335. Chapter 309: Epilepsy in Infants and Children - p. g1374 336. Chapter 310: Infant and Children Feeding Problems - p. g1379 337. Chapter 311: Infant Hyperbilirubinemia - p. g1382 338. Chapter 312: Mitochondrial Disease - p. g1387 339. Chapter 313: Multisystem Inflammatory Syndrome In Children, Post-COVID-19 - p. g1396 340. Chapter 314: Nocturnal Enuresis - p. g1399 341. Chapter 315: Obesity in Children - p. g1402 342. Chapter 316: Parenteral Fluid Therapy for Infants and Children - p. g1408 343. Chapter 317: Pediatric Failure to Thrive - p. g1414 344. Chapter 318: Pediatric Sleep Disorders - p. g1416 345. Chapter 319: Resuscitation of the Newborn - p. g1421 346. Chapter 320: Urinary Tract Infections in Infants and Children - p. g1428 347. Section 20: Physical and Chemical Injuries - p. g1430 348. Chapter 321: Burns - p. g1430 349. Chapter 322: Disturbances Due to Cold - p. g1437 350. Chapter 323: Heat Illness - p. g1443 351. Chapter 324: High-Altitude Illness - p. g1445 352. Chapter 325: Marine Poisonings, Envenomations, and Trauma - p. g1450 353. Chapter 326: Medical Toxicology - p. g1454 354. Chapter 327: Spider Bites and Scorpion Stings - p. g1454 355. Chapter 328: Venomous Snakebite - p. g1485 356. Section 21: Preventive Health - p. g1490 357. Chapter 329: Immunization Practices - p. g1490 358. Chapter 330: Travel Medicine - p. g1498 359. Section 22: Emerging Therapies - p. g1505 360. Chapter 331: Artificial Intelligence and Primary Care - p. g1505 361. Chapter 332: Genomic Testing - p. g1510 362. Chapter 333: Monoclonal Antibodies - p. g1514 363. Chapter 334: Stem Cell Therapy - p. g1519 364. Section 23: Appendix - p. g1523 365. Chapter 335: Biologic Agents Reference Chart - p. g1523 366. Chapter 336: Popular Herbs and Nutritional Supplements - p. g1526 367. Chapter 337: Toxic Chemical Agents Reference Chart - p. g1526 368. Index - p. g1541
Trusted by clinicians for more than 75 years, Conn’s Current Therapy presents today’s evidence-based information along with the personal experience and discernment of expert physicians. The 2025 edition is a helpful resource for a wide range of healthcare providers, including primary care physicians, subspecialists, and allied health professionals, providing current treatment information in a concise yet in-depth format. Nearly 350 topics have been carefully reviewed and updated to bring you state-of-the-art content in even the most rapidly changing areas of medicine.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Section 1: Symptomatic Care Pending Diagnosis - p. iii 8. List of Tables - p. iii 9. Chapter 1: Chest Pain - p. iii 10. Chapter 2: Constipation - p. iii 11. Chapter 3: Cough - p. iii 12. Chapter 4: Dizziness and Vertigo - p. iii 13. Chapter 5: Fatigue - p. iii 14. Chapter 6: Fever - p. iii 15. Chapter 7: Gaseousness, Indigestion, Nausea, and Vomiting - p. iii 16. Chapter 8: Hematuria - p. iii 17. Chapter 9: Hiccups - p. iii 18. Chapter 10: Hoarseness and Laryngitis - p. iii 19. Chapter 11: Leg Edema and Venous Stasis - p. iii 20. Chapter 12: Pain - p. iii 21. Chapter 13: Palliative and End-of-Life Care - p. iii 22. Chapter 14: Palpitations - p. g44 23. Chapter 15: Pharyngitis - p. g44 24. Chapter 16: Pruritis - p. g44 25. Chapter 17: Rhinitis - p. g44 26. Chapter 18: Spine Pain - p. g44 27. Chapter 19: Tinnitus - p. g44 28. Section 2: Allergy - p. g44 29. Chapter 20: Allergic Reactions to Insect Stings - p. g44 30. Chapter 21: Anaphylaxis - p. g44 31. Chapter 22: Drug Hypersensitivity Reactions - p. g44 32. Chapter 23: Serum Sickness - p. g44 33. Section 3: Cardiovascular System - p. g44 34. Chapter 24: Acute Myocardial Infarction - p. g44 35. Chapter 25: Angina Pectoris - p. g44 36. Chapter 26: Aortic Disease: Aneurysm and Dissection - p. g96 37. Chapter 27: Atrial Fibrillation - p. g113 38. Chapter 28: Congenital Heart Disease - p. g115 39. Chapter 29: Congestive Heart Failure - p. g121 40. Chapter 30: Heart Block - p. g126 41. Chapter 31: Hypertension - p. g131 42. Chapter 32: Hypertrophic Cardiomyopathy - p. g137 43. Chapter 33: Infective Endocarditis - p. g143 44. Chapter 34: Mitral Valve Prolapse - p. g147 45. Chapter 35: Pericarditis - p. g151 46. Chapter 36: Peripheral Artery Disease - p. g155 47. Chapter 37: Premature Beats - p. g159 48. Chapter 38: Tachycardias - p. g161 49. Chapter 39: Valvular Heart Disease - p. g167 50. Chapter 40: Venous Thrombosis - p. g172 51. Section 4: Digestive System - p. g178 52. Chapter 41: Acute and Chronic Pancreatitis - p. g178 53. Chapter 42: Acute Diarrhea - p. g186 54. Chapter 43: Bleeding Esophageal Varices - p. g192 55. Chapter 44: Calculous Biliary Disease - p. g198 56. Chapter 45: Chronic Diarrhea - p. g203 57. Chapter 46: Cirrhosis - p. g210 58. Chapter 47: Diverticula of the Alimentary Tract - p. g222 59. Chapter 48: Dysphagia and Esophageal Obstruction - p. g226 60. Chapter 49: Gastritis and Peptic Ulcer Disease - p. g232 61. Chapter 50: Gastroesophageal Reflux Disease (GERD) - p. g235 62. Chapter 51: Hemorrhoids, Anal Fissure, and Anorectal Abscess and Fistula - p. g238 63. Chapter 52: Hepatitis A, B, D, and E - p. g242 64. Chapter 53: Hepatitis C - p. g250 65. Chapter 54: Inflammatory Bowel Disease: Crohn’s Disease and Ulcerative Colitis - p. g252 66. Chapter 55: Intestinal Parasites - p. g261 67. Chapter 56: Irritable Bowel Syndrome - p. g276 68. Chapter 57: Malabsorption - p. g279 69. Chapter 58: Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) - p. g285 70. Chapter 59: Pancreatic Cancer - p. g293 71. Chapter 60: Tumors of the Colon and Rectum - p. g296 72. Chapter 61: Tumors of the Stomach - p. g301 73. Section 5: Endocrine and Metabolic Disorders - p. g305 74. Chapter 62: Acromegaly - p. g305 75. Chapter 63: Adrenocortical Insufficiency - p. g311 76. Chapter 64: Cushing’s Syndrome - p. g314 77. Chapter 65: Diabetes Insipidus - p. g320 78. Chapter 66: Diabetes Mellitus in Adults - p. g323 79. Chapter 67: Diabetic Ketoacidosis - p. g337 80. Chapter 68: Gender-Affirming Care - p. g342 81. Chapter 69: Gout and Hyperuricemia - p. g347 82. Chapter 70: Hyperaldosteronism - p. g350 83. Chapter 71: Hyperlipidemia - p. g358 84. Chapter 72: Hyperparathyroidism and Hypoparathyroidism - p. g369 85. Chapter 73: Hyperprolactinemia - p. g377 86. Chapter 74: Hyperthyroidism - p. g384 87. Chapter 75: Hypokalemia and Hyperkalemia - p. g388 88. Chapter 76: Hyponatremia - p. g391 89. Chapter 77: Hypopituitarism - p. g398 90. Chapter 78: Hypothyroidism - p. g402 91. Chapter 79: Obesity in Adults - p. g404 92. Chapter 80: Parenteral Nutrition in Adults - p. g410 93. Chapter 81: Pheochromocytoma - p. g420 94. Chapter 82: Thyroid Cancer - p. g429 95. Chapter 83: Thyroiditis - p. g434 96. Section 6: Hematology - p. g436 97. Chapter 84: Acute Leukemia in Adults - p. g436 98. Chapter 85: Blood Component Therapy and Transfusion Reactions - p. g442 99. Chapter 86: Chronic Leukemias - p. g449 100. Chapter 87: Disseminated Intravascular Coagulation - p. g455 101. Chapter 88: Hemochromatosis - p. g458 102. Chapter 89: Hemolytic Anemias - p. g461 103. Chapter 90: Hemophilia and Related Conditions - p. g467 104. Chapter 91: Hodgkin Disease - p. g475 105. Chapter 92: Iron Deficiency Anemia - p. g478 106. Chapter 93: Megaloblastic Anemias - p. g481 107. Chapter 94: Multiple Myeloma - p. g484 108. Chapter 95: Myelodysplastic Syndromes - p. g489 109. Chapter 96: Lymphoma - p. g493 110. Chapter 97: Platelet-Mediated Bleeding Disorders - p. g503 111. Chapter 98: Polycythemia Vera - p. g507 112. Chapter 99: Porphyrias - p. g511 113. Chapter 100: Sickle Cell Disease - p. g514 114. Chapter 101: Thalassemia - p. g527 115. Chapter 102: Thrombotic Thrombocytopenic Purpura - p. g533 116. Section 7: Head and Neck - p. g537 117. Chapter 103: Dry Eye Syndrome - p. g537 118. Chapter 104: Glaucoma - p. g541 119. Chapter 105: Ménière’s Disease - p. g545 120. Chapter 106: Otitis Externa - p. g549 121. Chapter 107: Otitis Media - p. g551 122. Chapter 108: Red Eye - p. g555 123. Chapter 109: Rhinosinusitis - p. g560 124. Chapter 110: Temporomandibular Disorders - p. g562 125. Chapter 111: Uveitis - p. g565 126. Chapter 112: Vision Rehabilitation - p. g572 127. Section 8: Infectious Diseases - p. g576 128. Chapter 113: Amebiasis - p. g576 129. Chapter 114: Anthrax - p. g581 130. Chapter 115: Babesiosis - p. g584 131. Chapter 116: Bacterial Meningitis - p. g585 132. Chapter 117: Brucellosis - p. g589 133. Chapter 118: Clostridioides Difficile Colitis - p. g593 134. Chapter 119: Cat Scratch Disease - p. g596 135. Chapter 120: Chikungunya - p. g598 136. Chapter 121: Cholera - p. g600 137. Chapter 122: COVID-19 - p. g603 138. Chapter 123: Ebola Virus Disease - p. g607 139. Chapter 124: Foodborne Illnesses - p. g610 140. Chapter 125: Giardiasis - p. g621 141. Chapter 126: Human Immunodeficiency Virus: Treatment and Prevention - p. g624 142. Chapter 127: Infectious Mononucleosis - p. g638 143. Chapter 128: Influenza - p. g639 144. Chapter 129: Leishmaniasis - p. g643 145. Chapter 130: Leprosy - p. g648 146. Chapter 131: Lyme Disease and Post-Treatment Lyme Disease Syndrome - p. g654 147. Chapter 132: Malaria - p. g658 148. Chapter 133: Measles (Rubeola) - p. g669 149. Chapter 134: Methicillin-Resistant Staphylococcus Aureus - p. g672 150. Chapter 135: Mpox - p. g677 151. Chapter 136: Mumps - p. g685 152. Chapter 137: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - p. g686 153. Chapter 138: Necrotizing Skin and Soft-Tissue Infections - p. g689 154. Chapter 139: Osteomyelitis - p. g691 155. Chapter 140: Plague - p. g698 156. Chapter 141: Post-Acute COVID Syndrome - p. g700 157. Chapter 142: Psittacosis - p. g707 158. Chapter 143: Q Fever - p. g708 159. Chapter 144: Rabies - p. g710 160. Chapter 145: Rat-Bite Fever - p. g712 161. Chapter 146: Relapsing Fever - p. g714 162. Chapter 147: Rubella and Congenital Rubella - p. g718 163. Chapter 148: Salmonellosis - p. g720 164. Chapter 149: Sepsis - p. g723 165. Chapter 150: Smallpox - p. g727 166. Chapter 151: Tetanus - p. g731 167. Chapter 152: Tickborne Rickettsial Diseases (Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis) - p. g735 168. Chapter 153: Toxic Shock Syndrome - p. g739 169. Chapter 154: Toxoplasmosis - p. g741 170. Chapter 155: Typhoid Fever - p. g745 171. Chapter 156: Tamilarasu Kadhiravan, MD Varicella (Chickenpox) - p. g747 172. Chapter 157: Viral Meningitis - p. g750 173. Chapter 158: Whooping Cough (Pertussis) - p. g753 174. Chapter 159: Yellow Fever - p. g755 175. Chapter 160: Zika Virus Disease - p. g758 176. Section 9: Neurological System - p. g762 177. Chapter 161: Acute Facial Paralysis - p. g762 178. Chapter 162: Alzheimer’s Disease - p. g765 179. Chapter 163: Central Nervous System Neoplasms - p. g773 180. Chapter 164: Gilles de la Tourette Syndrome - p. g779 181. Chapter 165: Intracerebral Hemorrhage - p. g782 182. Chapter 166: Ischemic Cerebrovascular Disease - p. g789 183. Chapter 167: Migraine - p. g791 184. Chapter 168: Multiple Sclerosis - p. g797 185. Chapter 169: Myasthenia Gravis - p. g806 186. Chapter 170: Neurofibromatosis (Type 1) - p. g810 187. Chapter 171: Nonmigraine Headache - p. g814 188. Chapter 172: Optic Neuritis - p. g818 189. Chapter 173: Parkinson Disease - p. g819 190. Chapter 174: Rehabilitation of the Stroke Patient - p. g826 191. Chapter 175: Seizures and Epilepsy in Adolescents and Adults - p. g830 192. Chapter 176: Sleep Disorders - p. g840 193. Chapter 177: Sports-Related Head Injuries - p. g855 194. Chapter 178: Targeted Temperature Management (Therapeutic Hypothermia) - p. g860 195. Chapter 179: Trigeminal Neuralgia - p. g862 196. Section 10: Psychiatric Disorders - p. g864 197. Chapter 180: Alcohol Use Disorder - p. g864 198. Chapter 181: Autism Spectrum Disorder - p. g869 199. Chapter 182: Delirium - p. g873 200. Chapter 183: Depressive (Major) and Bipolar Disorder - p. g876 201. Chapter 184: Drug Use Disorders - p. g882 202. Chapter 185: Eating Disorders - p. g888 203. Chapter 186: Generalized Anxiety Disorder - p. g893 204. Chapter 187: Obsessive-Compulsive Disorder - p. g896 205. Chapter 188: Panic Disorder - p. g898 206. Chapter 189: Posttraumatic Stress Disorder - p. g901 207. Chapter 190: Schizophrenia - p. g905 208. Section 11: Respiratory System - p. g909 209. Chapter 191: Acute Bronchitis and Other Viral Respiratory Infections - p. g909 210. Chapter 192: Acute Respiratory Failure - p. g913 211. Chapter 193: Asthma in Adolescents and Adults - p. g918 212. Chapter 194: Atelectasis - p. g926 213. Chapter 195: Bacterial Pneumonia - p. g926 214. Chapter 196: Blastomycosis - p. g932 215. Chapter 197: Chronic Obstructive Pulmonary Disease - p. g936 216. Chapter 198: Coccidioidomycosis - p. g943 217. Chapter 199: Cystic Fibrosis - p. g945 218. Chapter 200: Histoplasmosis - p. g950 219. Chapter 201: Hypersensitivity Pneumonitis - p. g954 220. Chapter 202: Legionellosis (Legionnaire’s Disease and Pontiac Fever) - p. g955 221. Chapter 203: Lung Abscess - p. g957 222. Chapter 204: Lung Cancer - p. g959 223. Chapter 205: Obstructive Sleep Apnea - p. g970 224. Chapter 206: Pleural Effusion and Empyema - p. g973 225. Chapter 207: Pneumoconiosis: Asbestosis and Silicosis - p. g980 226. Chapter 208: Pulmonary Hypertension - p. g979 227. Chapter 209: Sarcoidosis - p. g984 228. Chapter 210: Tuberculosis and Other Mycobacterial Diseases - p. g988 229. Chapter 211: Venous Thromboembolism - p. g996 230. Chapter 212: Viral and Mycoplasmal Pneumonias - p. g1008 231. Chapter 213: Viral Respiratory Infections - p. g1013 232. Section 12: Rheumatology and the Musculoskeletal System - p. g1016 233. Chapter 214: Axial Spondyloarthritis - p. g1016 234. Chapter 215: Common Sports Injuries - p. g1020 235. Chapter 216: Connective Tissue Disorders - p. g1031 236. Chapter 217: Fibromyalgia - p. g1035 237. Chapter 218: Juvenile Idiopathic Arthritis - p. g1039 238. Chapter 219: Osteoarthritis - p. g1045 239. Chapter 220: Osteoporosis - p. g1048 240. Chapter 221: Paget’s Disease of Bone - p. g1053 241. Chapter 222: Polymyalgia Rheumatica and Giant Cell Arteritis - p. g1056 242. Chapter 223: Psoriatic Arthritis - p. g1059 243. Chapter 224: Rheumatoid Arthritis - p. g1063 244. Chapter 225: Tendinopathy and Bursitis - p. g1068 245. Section 13: Sexually Transmitted Diseases - p. g1071 246. Chapter 226: Chlamydia Trachomatis - p. g1071 247. Chapter 227: Condylomata Acuminata - p. g1075 248. Chapter 228: Genital Ulcer Disease: Chancroid, Granuloma Inguinale, and Lymphogranuloma - p. g1077 249. Chapter 229: Gonorrhea - p. g1080 250. Chapter 230: Non-Gonococcal Urethritis - p. g1083 251. Chapter 231: Syphilis - p. g1085 252. Section 14: Skin Disease - p. g1088 253. Chapter 232: Acne Vulgaris - p. g1088 254. Chapter 233: Atopic Dermatitis - p. g1092 255. Chapter 234: Autoimmune Bullous Diseases - p. g1096 256. Chapter 235: Bacterial Diseases of the Skin - p. g1100 257. Chapter 236: Contact Dermatitis - p. g1103 258. Chapter 237: Cutaneous T-Cell Lymphomas, Including Mycosis Fungoides and Sézary Syndrome - p. g1106 259. Chapter 238: Cutaneous Vasculitis - p. g1112 260. Chapter 239: Diseases of the Hair - p. g1115 261. Chapter 240: Diseases of the Mouth - p. g1118 262. Chapter 241: Diseases of the Nail - p. g1124 263. Chapter 242: Erythema Multiforme - p. g1127 264. Chapter 243: Fungal Infections of the Skin - p. g1129 265. Chapter 244: Keloids and Hypertrophic Scars - p. g1132 266. Chapter 245: Melanoma - p. g1136 267. Chapter 246: Nevi - p. g1140 268. Chapter 247: Nonmelanoma Cancer of the Skin - p. g1144 269. Chapter 248: Papulosquamous Eruptions - p. g1148 270. Chapter 249: Parasitic Diseases of the Skin - p. g1154 271. Chapter 250: Pigmentary Disorders - p. g1159 272. Chapter 251: Premalignant Skin Lesions - p. g1162 273. Chapter 252: Pressure Injury - p. g1165 274. Chapter 253: Pruritus Ani and Vulvae - p. g1167 275. Chapter 254: Pyoderma Gangrenosum - p. g1171 276. Chapter 255: Rosacea - p. g1174 277. Chapter 256: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis - p. g1175 278. Chapter 257: Sunburn - p. g1177 279. Chapter 258: Urticaria and Angioedema - p. g1179 280. Chapter 259: Venous Ulcers - p. g1181 281. Chapter 260: Viral Diseases of the Skin - p. g1184 282. Chapter 261: Warts (Verrucae) - p. g1190 283. Section 15: Urogenital Tract - p. g1193 284. Chapter 262: Acute Kidney Injury - p. g1193 285. Chapter 263: Chronic Kidney Disease - p. g1198 286. Chapter 264: Malignant Tumors of the Urogenital Tract - p. g1206 287. Chapter 265: Nephrolithiasis - p. g1213 288. Chapter 266: Primary Glomerular Disease - p. g1216 289. Chapter 267: Pyelonephritis - p. g1221 290. Chapter 268: Trauma to the Genitourinary Tract - p. g1224 291. Chapter 269: Urethral Stricture Disease - p. g1227 292. Chapter 270: Urinary Incontinence - p. g1229 293. Section 16: Men’s Health - p. g1231 294. Chapter 271: Benign Prostatic Hyperplasia - p. g1231 295. Chapter 272: Epididymitis and Orchitis - p. g1236 296. Chapter 273: Erectile Dysfunction - p. g1238 297. Chapter 274: Prostate Cancer - p. g1241 298. Chapter 275: Prostatitis - p. g1246 299. Chapter 276: Urinary Tract Infections in the Male - p. g1248 300. Section 17: Women’s Health - p. g1251 301. Chapter 277: Abnormal Uterine Bleeding - p. g1251 302. Chapter 278: Amenorrhea - p. g1254 303. Chapter 279: Bacterial Infections of the Urinary Tract in Women - p. g1258 304. Chapter 280: Benign Breast Disease - p. g1260 305. Chapter 281: Breast Cancer - p. g1264 306. Chapter 282: Cancer of the Endometrium - p. g1267 307. Chapter 283: Cancer of the Uterine Cervix - p. g1270 308. Chapter 284: Contraception - p. g1274 309. Chapter 285: Dysmenorrhea - p. g1278 310. Chapter 286: Endometriosis - p. g1280 311. Chapter 287: Female Sexual Concerns - p. g1283 312. Chapter 288: Infertility - p. g1287 313. Chapter 289: Menopause - p. g1289 314. Chapter 290: Ovarian Cancer - p. g1293 315. Chapter 291: Pelvic Inflammatory Disease - p. g1296 316. Chapter 292: Premenstrual Dysphoric Disorder - p. g1298 317. Chapter 293: Uterine Leiomyoma - p. g1301 318. Chapter 294: Vulvar Neoplasia - p. g1305 319. Chapter 295: Vulvovaginitis - p. g1307 320. Section 18: Pregnancy and Antepartum Care - p. g1311 321. Chapter 296: Antepartum Care - p. g1311 322. Chapter 297: Ectopic Pregnancy - p. g1320 323. Chapter 298: Hypertensive Disorders in Pregnancy - p. g1323 324. Chapter 299: Postpartum Care - p. g1328 325. Chapter 300: Postpartum Depression - p. g1329 326. Chapter 301: Vaginal Bleeding in Pregnancy - p. g1332 327. Section 19: Children’s Health - p. g1335 328. Chapter 302: Acute Leukemia in Children - p. g1335 329. Chapter 303: Adolescent Health - p. g1344 330. Chapter 304: Asthma in Children - p. g1348 331. Chapter 305: Attention-Deficit/Hyperactivity Disorder - p. g1355 332. Chapter 306: Bronchiolitis - p. g1364 333. Chapter 307: Diabetes Mellitus in Children - p. g1367 334. Chapter 308: Encopresis - p. g1372 335. Chapter 309: Epilepsy in Infants and Children - p. g1374 336. Chapter 310: Infant and Children Feeding Problems - p. g1379 337. Chapter 311: Infant Hyperbilirubinemia - p. g1382 338. Chapter 312: Mitochondrial Disease - p. g1387 339. Chapter 313: Multisystem Inflammatory Syndrome In Children, Post-COVID-19 - p. g1396 340. Chapter 314: Nocturnal Enuresis - p. g1399 341. Chapter 315: Obesity in Children - p. g1402 342. Chapter 316: Parenteral Fluid Therapy for Infants and Children - p. g1408 343. Chapter 317: Pediatric Failure to Thrive - p. g1414 344. Chapter 318: Pediatric Sleep Disorders - p. g1416 345. Chapter 319: Resuscitation of the Newborn - p. g1421 346. Chapter 320: Urinary Tract Infections in Infants and Children - p. g1428 347. Section 20: Physical and Chemical Injuries - p. g1430 348. Chapter 321: Burns - p. g1430 349. Chapter 322: Disturbances Due to Cold - p. g1437 350. Chapter 323: Heat Illness - p. g1443 351. Chapter 324: High-Altitude Illness - p. g1445 352. Chapter 325: Marine Poisonings, Envenomations, and Trauma - p. g1450 353. Chapter 326: Medical Toxicology - p. g1454 354. Chapter 327: Spider Bites and Scorpion Stings - p. g1454 355. Chapter 328: Venomous Snakebite - p. g1485 356. Section 21: Preventive Health - p. g1490 357. Chapter 329: Immunization Practices - p. g1490 358. Chapter 330: Travel Medicine - p. g1498 359. Section 22: Emerging Therapies - p. g1505 360. Chapter 331: Artificial Intelligence and Primary Care - p. g1505 361. Chapter 332: Genomic Testing - p. g1510 362. Chapter 333: Monoclonal Antibodies - p. g1514 363. Chapter 334: Stem Cell Therapy - p. g1519 364. Section 23: Appendix - p. g1523 365. Chapter 335: Biologic Agents Reference Chart - p. g1523 366. Chapter 336: Popular Herbs and Nutritional Supplements - p. g1526 367. Chapter 337: Toxic Chemical Agents Reference Chart - p. g1526 368. Index - p. g1541
