Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs.
This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science.
1. Contemporary Chemical Approaches for Green and Sustainable Drugs - p. i 2. Cover - p. i 3. Title Page - p. ii 4. Copyright - p. iii 5. Table of Contents - p. iv 6. List of contributors - p. xiii 7. Chapter 1 Using the zebrafish model system to identify the health effects of pharmaceutical pollutants - p. 1 8. Chapter 2 Analysis of pharmaceuticals in the environment - p. 27 9. Chapter 3 Leaking of antibiotics in the aquatic environment - p. 47 10. Chapter 4 Advances in drug development with the application of artificial intelligence - p. 69 11. Chapter 5 Virtual screening techniques in pharmaceutical research - p. 89 12. Chapter 6 In silico modeling of environmental toxicity of drugs - p. 129 13. Chapter 7 Sustainable separations in pharmaceutical manufacturing - p. 155 14. Chapter 8 Green synthetic methods in drug discovery and development - p. 201 15. Chapter 9 Characterizing the environmentally benign nature of chemical processes - p. 281 16. Chapter 10 Green chemistry approaches to drugs that treat epidemic and pandemic diseases - p. 307 17. Chapter 11 Dynamic effects of organic molecules for drug delivery in micelles - p. 333 18. Chapter 12 Antibody-drug conjugates for targeted delivery - p. 377 19. Chapter 13 Toward the green synthesis of peptides and peptidic drugs - p. 421 20. Chapter 14 The multitarget approach as a green tool in medicinal chemistry - p. 457 21. Chapter 15 Directed evolution - p. 493 22. Chapter 16 Conventional and advanced treatment methods for the removal of pharmaceuticals and related compounds in wastewater - p. 511 23. Index - p. 535
Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs.
This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science.
1. Contemporary Chemical Approaches for Green and Sustainable Drugs - p. i 2. Cover - p. i 3. Title Page - p. ii 4. Copyright - p. iii 5. Table of Contents - p. iv 6. List of contributors - p. xiii 7. Chapter 1 Using the zebrafish model system to identify the health effects of pharmaceutical pollutants - p. 1 8. Chapter 2 Analysis of pharmaceuticals in the environment - p. 27 9. Chapter 3 Leaking of antibiotics in the aquatic environment - p. 47 10. Chapter 4 Advances in drug development with the application of artificial intelligence - p. 69 11. Chapter 5 Virtual screening techniques in pharmaceutical research - p. 89 12. Chapter 6 In silico modeling of environmental toxicity of drugs - p. 129 13. Chapter 7 Sustainable separations in pharmaceutical manufacturing - p. 155 14. Chapter 8 Green synthetic methods in drug discovery and development - p. 201 15. Chapter 9 Characterizing the environmentally benign nature of chemical processes - p. 281 16. Chapter 10 Green chemistry approaches to drugs that treat epidemic and pandemic diseases - p. 307 17. Chapter 11 Dynamic effects of organic molecules for drug delivery in micelles - p. 333 18. Chapter 12 Antibody-drug conjugates for targeted delivery - p. 377 19. Chapter 13 Toward the green synthesis of peptides and peptidic drugs - p. 421 20. Chapter 14 The multitarget approach as a green tool in medicinal chemistry - p. 457 21. Chapter 15 Directed evolution - p. 493 22. Chapter 16 Conventional and advanced treatment methods for the removal of pharmaceuticals and related compounds in wastewater - p. 511 23. Index - p. 535
