Coronavirus Drug Discovery, Volume 1: SARS-CoV-2 (COVID-19) Prevention, Diagnosis, and Treatment is the first of three volumes presenting comprehensive information on drug discovery against COVID-19. This volume provides background information on the genesis of COVID-19, the epidemiology, transmission, pathogenesis, and mutagenesis. It also presents the various treatment options, drug discovery opportunities and vaccine developmental processes. Written by global team of experts from key institutions across the globe, this book is recommended to all concerned agencies, private research firms, and consortiums working on finding a solution to COVID-19 and its variants. By design, this book will be useful to drug developers, medicinal chemists, pharmacologists, health experts, researchers, students and faculty members in industry and academia.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xv 7. Part I: Coronavirus pandemic and countermeasures - p. xix 8. Chapter 1. Coronavirus pandemic: History, overview of different strains of coronaviruses and what went wrong - p. 3 9. Chapter 2. COVID-19 outbreak: comprehensive update on epidemiology, transmission, and treatment opportunities - p. 17 10. Chapter 3. Biomarkers, tools, and test kits for COVID-19 - p. 37 11. Chapter 4. Testing and diagnosis of SARS-CoV-2 infection - p. 49 12. Chapter 5. Pathogenesis and mutagenesis of SARS-CoV-2: cellular attachment, entry, and infection - p. 81 13. Chapter 6. Therapeutic options in coronavirus treatment: COVID-19 drug discovery update - p. 101 14. Chapter 7. Current therapeutic strategies to combat coronavirus disease 2019 - p. 137 15. Chapter 8. Myth surrounding the FDA disapproval of hydroxychloroquine sulfate and chloroquine phosphate as drugs for coronavirus disease 2019 - p. 153 16. Chapter 9. Dexamethasone: a corticosteroid drug for the treatment of coronavirus disease 2019 - p. 169 17. Chapter 10. Drug combination therapies for SARS-CoV-2 (COVID-19) treatment - p. 181 18. Chapter 11. Drug repurposing for SARS-CoV-2 (COVID-19) treatment - p. 205 19. Chapter 12. SARS-CoV-2 vaccine development - p. 227 20. Chapter 13. FDA Coronavirus Treatment Acceleration Program: approved drugs and those in clinical trials - p. 249 21. Part II: Global impacts and collaborative efforts against COVID-19 - p. 261 22. Chapter 14. The coronavirus global pandemic and its impacts on society - p. 267 23. Chapter 15. Coronavirus disease 2019 in Africa: why the recent spike in cases? - p. 313 24. Chapter 16. Interdisciplinary approach to biomedical research: a panacea to efficient research output during the global pandemic - p. 331 25. Chapter 17. Roles of online social media platforms and artificial intelligence in diffusing the impact of COVID-19 as scientists find a cure - p. 349 26. Index - p. 363
Coronavirus Drug Discovery, Volume 1: SARS-CoV-2 (COVID-19) Prevention, Diagnosis, and Treatment is the first of three volumes presenting comprehensive information on drug discovery against COVID-19. This volume provides background information on the genesis of COVID-19, the epidemiology, transmission, pathogenesis, and mutagenesis. It also presents the various treatment options, drug discovery opportunities and vaccine developmental processes. Written by global team of experts from key institutions across the globe, this book is recommended to all concerned agencies, private research firms, and consortiums working on finding a solution to COVID-19 and its variants. By design, this book will be useful to drug developers, medicinal chemists, pharmacologists, health experts, researchers, students and faculty members in industry and academia.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xv 7. Part I: Coronavirus pandemic and countermeasures - p. xix 8. Chapter 1. Coronavirus pandemic: History, overview of different strains of coronaviruses and what went wrong - p. 3 9. Chapter 2. COVID-19 outbreak: comprehensive update on epidemiology, transmission, and treatment opportunities - p. 17 10. Chapter 3. Biomarkers, tools, and test kits for COVID-19 - p. 37 11. Chapter 4. Testing and diagnosis of SARS-CoV-2 infection - p. 49 12. Chapter 5. Pathogenesis and mutagenesis of SARS-CoV-2: cellular attachment, entry, and infection - p. 81 13. Chapter 6. Therapeutic options in coronavirus treatment: COVID-19 drug discovery update - p. 101 14. Chapter 7. Current therapeutic strategies to combat coronavirus disease 2019 - p. 137 15. Chapter 8. Myth surrounding the FDA disapproval of hydroxychloroquine sulfate and chloroquine phosphate as drugs for coronavirus disease 2019 - p. 153 16. Chapter 9. Dexamethasone: a corticosteroid drug for the treatment of coronavirus disease 2019 - p. 169 17. Chapter 10. Drug combination therapies for SARS-CoV-2 (COVID-19) treatment - p. 181 18. Chapter 11. Drug repurposing for SARS-CoV-2 (COVID-19) treatment - p. 205 19. Chapter 12. SARS-CoV-2 vaccine development - p. 227 20. Chapter 13. FDA Coronavirus Treatment Acceleration Program: approved drugs and those in clinical trials - p. 249 21. Part II: Global impacts and collaborative efforts against COVID-19 - p. 261 22. Chapter 14. The coronavirus global pandemic and its impacts on society - p. 267 23. Chapter 15. Coronavirus disease 2019 in Africa: why the recent spike in cases? - p. 313 24. Chapter 16. Interdisciplinary approach to biomedical research: a panacea to efficient research output during the global pandemic - p. 331 25. Chapter 17. Roles of online social media platforms and artificial intelligence in diffusing the impact of COVID-19 as scientists find a cure - p. 349 26. Index - p. 363
