The definitive reference in the field for more than 35 years, Creasy and Resnik's Maternal-Fetal Medicine provides today’s MFM practitioners with authoritative, comprehensive guidance on every aspect of this fast-changing field. The fully revised 9th Edition brings you up to date with the latest evidence-based guidelines and research as well as the fundamental scientific foundation needed for effective practice, helping you minimize complications and ensure the best possible outcomes for your patients. Renowned experts in obstetrics, gynecology, and perinatology provide valuable information in every area of complex obstetric care, highlighting the most commonly encountered anomalies and providing clear guidelines for obstetric and neonatal management.
Offers comprehensive updates on rapidly changing topics, including extensively revised genetic content throughout.
Includes two new chapters: maternal and fetal viral infections, including COVID-19; and sexually transmitted disease, covering the epidemiology, pathogenesis, diagnosis, and treatment of individual infectious diseases that may complicate pregnancy.
Contains user-friendly features such as numerous diagnostic and treatment algorithms for quick access to current protocols; key points at the end of each chapter; and counseling pearls with practical guidance on patient consultation.
Features a comprehensive imaging section, including a video library to aid in everyday diagnosis.
Shares the expertise of a renowned editorial team—including new co-editors Drs. Lorraine Dugoff and Judette M. Louis—who lead authors representing top institutions from around the globe.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. iii 6. Contributors - p. iii 7. Preface - p. iii 8. List of Illustrations - p. iii 9. List of Tables - p. iii 10. Part 1: Scientific Basis of Perinatal Biology - p. iii 11. Chapter 1: Human Genetics and Patterns of Inheritance - p. iii 12. Chapter 2: Molecular Genetic Technology - p. g16 13. Chapter 3: Normal Early Development - p. g41.e1 14. Chapter 4: Amniotic Fluid Dynamics - p. g65 15. Chapter 5: Multiple Gestation: The Biology of Twinning - p. g71 16. Chapter 6: Physiology of Parturition - p. g84.e1 17. Chapter 7: Pathogenesis of Spontaneous Preterm Birth - p. g101 18. Chapter 8: Immunology of Pregnancy - p. g126.e1 19. Chapter 9: Maternal Cardiovascular, Respiratory, and Renal Adaptation to Pregnancy - p. g142.e1 20. Chapter 10: Endocrinology of Pregnancy - p. g150 21. Chapter 11: The Breast and the Physiology of Lactation - p. g162 22. Chapter 12: Maternal Nutrition - p. g185 23. Chapter 13: Fetal Cardiovascular Physiology - p. g193.e1 24. Chapter 14: Placental Respiratory Gas Exchange and Fetal Oxygenation - p. g203.e1 25. Chapter 15: Evidence-Based Practice in Perinatal Medicine - p. g216.e1 26. Part 2: Obstetric Imaging - p. g230.e1 27. Chapter 16: Performing and Documenting the Fetal Anatomy Ultrasound Examination - p. g230.e1 28. Chapter 17: Doppler Ultrasound: Select Fetal and Maternal Applications - p. g236 29. Chapter 18: Clinical Applications of Three-Dimensional Sonography in Obstetrics - p. g253.e1 30. Chapter 19: Role of Magnetic Resonance Imaging in Obstetric Imaging - p. g272.e1 31. Chapter 20: Fetal Central Nervous System Imaging - p. g283 32. Chapter 21: Imaging of the Fetal Face and Neck - p. g302.e15 33. Chapter 22: Fetal Thoracic Imaging - p. g314.e1 34. Chapter 23: Fetal Cardiac Malformations and Arrhythmias: Detection, Diagnosis, Management, and Prognosis - p. g321.e6 35. Chapter 24: Fetal Abdominal Imaging - p. g365.e1 36. Chapter 25: Fetal Urogenital Imaging - p. g399.e1 37. Chapter 26: Skeletal Imaging - p. g432.e1 38. Chapter 27: Placenta and Umbilical Cord Imaging - p. g471.e1 39. Chapter 28: Uterus and Adnexae Imaging - p. g482.e8 40. Chapter 29: First-Trimester Imaging - p. g488.e1 41. Part 3: Fetal Disorders: Diagnosis and Therapy - p. g499 42. Chapter 30: Prenatal Diagnosis of Congenital Disorders - p. g499 43. Chapter 31: Teratogenesis and Environmental Exposure - p. g548.e1 44. Chapter 32: Assessment of Fetal Health - p. g559.e1 45. Chapter 33: Intrapartum Fetal Surveillance - p. g573 46. Chapter 34: Invasive Fetal Therapy - p. g594.e1 47. Chapter 35: Hemolytic Disease of the Fetus and Newborn - p. g633.e1 48. Chapter 36: Nonimmune Hydrops - p. g649.e1 49. Chapter 37: Multiple Gestation: Clinical Characteristics and Management - p. g659.e1 50. Part 4: Disorders at the Maternal-Fetal Interface - p. g685 51. Chapter 38: Prevention and Management of Preterm Parturition - p. g685 52. Chapter 39: Premature (Prelabor) Rupture of the Membranes - p. g722 53. Chapter 40: Clinical Aspects of Normal and Abnormal Labor - p. g733 54. Chapter 41: Recurrent Pregnancy Loss - p. g767 55. Chapter 42: Stillbirth - p. g781 56. Chapter 43: Placenta Previa and Accreta, Vasa Previa, Subchorionic Hemorrhage, and Abruptio Placentae - p. g798 57. Chapter 44: Fetal Growth Restriction - p. g809 58. Chapter 45: Pregnancy-Related Hypertension - p. g825 59. Part 5: Maternal Complications - p. g854 60. Chapter 46: Patient Safety and Quality Improvement in Obstetrics - p. g854 61. Chapter 47: Maternal Mortality - p. g866 62. Chapter 48: Bacterial and Parasitic Infections in Pregnancy - p. g878 63. Chapter 49: Maternal and Fetal Viral Infections - p. g907 64. Chapter 50: Sexually Transmitted Diseases - p. g937 65. Chapter 51: Maternal-Fetal Infections - p. g958 66. Chapter 52: Cardiac Diseases - p. g972.e1 67. Chapter 53: Coagulation Disorders in Pregnancy - p. g1012.e1 68. Chapter 54: Thromboembolic Disease in Pregnancy - p. g1038.e1 69. Chapter 55: Anemia and Pregnancy - p. g1053.e1 70. Chapter 56: Malignancy and Pregnancy - p. g1069.e1 71. Chapter 57: Renal Disorders - p. g1087.e1 72. Chapter 58: Respiratory Diseases in Pregnancy - p. g1105.e1 73. Chapter 59: Diabetes in Pregnancy - p. g1131 74. Chapter 60: Pregnancy in Women With Obesity - p. g1165.e1 75. Chapter 61: Thyroid Disease and Pregnancy - p. g1186.e1 76. Chapter 62: Other Endocrine Disorders of Pregnancy - p. g1213 77. Chapter 63: Gastrointestinal Disease in Pregnancy - p. g1240 78. Chapter 64: Diseases of the Liver, Biliary System, and Pancreas - p. g1256 79. Chapter 65: Pregnancy and Rheumatic Diseases - p. g1276 80. Chapter 66: Neurologic Disorders - p. g1292 81. Chapter 67: Management of Depression and Psychoses in Pregnancy and in the Puerperium - p. g1316 82. Chapter 68: Substance Use and Addiction in Pregnancy and the Postpartum Period - p. g1327 83. Chapter 69: The Skin and Pregnancy - p. g1356 84. Chapter 70: Anesthesia Considerations for Complicated Pregnancies - p. g1367 85. Chapter 71: Intensive Care Considerations in Obstetrics - p. g1386 86. Chapter 72: Pregnancy as a Window to Future Health - p. g1400 87. Part 6: The Neonate - p. g1407 88. Chapter 73: Neonatal Morbidities of Prenatal and Perinatal Origin - p. g1407 89. Index - p. g1438 90. Normal Laboratory Values in Pregnancy - p. g1438
The definitive reference in the field for more than 35 years, Creasy and Resnik's Maternal-Fetal Medicine provides today’s MFM practitioners with authoritative, comprehensive guidance on every aspect of this fast-changing field. The fully revised 9th Edition brings you up to date with the latest evidence-based guidelines and research as well as the fundamental scientific foundation needed for effective practice, helping you minimize complications and ensure the best possible outcomes for your patients. Renowned experts in obstetrics, gynecology, and perinatology provide valuable information in every area of complex obstetric care, highlighting the most commonly encountered anomalies and providing clear guidelines for obstetric and neonatal management.
Offers comprehensive updates on rapidly changing topics, including extensively revised genetic content throughout.
Includes two new chapters: maternal and fetal viral infections, including COVID-19; and sexually transmitted disease, covering the epidemiology, pathogenesis, diagnosis, and treatment of individual infectious diseases that may complicate pregnancy.
Contains user-friendly features such as numerous diagnostic and treatment algorithms for quick access to current protocols; key points at the end of each chapter; and counseling pearls with practical guidance on patient consultation.
Features a comprehensive imaging section, including a video library to aid in everyday diagnosis.
Shares the expertise of a renowned editorial team—including new co-editors Drs. Lorraine Dugoff and Judette M. Louis—who lead authors representing top institutions from around the globe.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. iii 6. Contributors - p. iii 7. Preface - p. iii 8. List of Illustrations - p. iii 9. List of Tables - p. iii 10. Part 1: Scientific Basis of Perinatal Biology - p. iii 11. Chapter 1: Human Genetics and Patterns of Inheritance - p. iii 12. Chapter 2: Molecular Genetic Technology - p. g16 13. Chapter 3: Normal Early Development - p. g41.e1 14. Chapter 4: Amniotic Fluid Dynamics - p. g65 15. Chapter 5: Multiple Gestation: The Biology of Twinning - p. g71 16. Chapter 6: Physiology of Parturition - p. g84.e1 17. Chapter 7: Pathogenesis of Spontaneous Preterm Birth - p. g101 18. Chapter 8: Immunology of Pregnancy - p. g126.e1 19. Chapter 9: Maternal Cardiovascular, Respiratory, and Renal Adaptation to Pregnancy - p. g142.e1 20. Chapter 10: Endocrinology of Pregnancy - p. g150 21. Chapter 11: The Breast and the Physiology of Lactation - p. g162 22. Chapter 12: Maternal Nutrition - p. g185 23. Chapter 13: Fetal Cardiovascular Physiology - p. g193.e1 24. Chapter 14: Placental Respiratory Gas Exchange and Fetal Oxygenation - p. g203.e1 25. Chapter 15: Evidence-Based Practice in Perinatal Medicine - p. g216.e1 26. Part 2: Obstetric Imaging - p. g230.e1 27. Chapter 16: Performing and Documenting the Fetal Anatomy Ultrasound Examination - p. g230.e1 28. Chapter 17: Doppler Ultrasound: Select Fetal and Maternal Applications - p. g236 29. Chapter 18: Clinical Applications of Three-Dimensional Sonography in Obstetrics - p. g253.e1 30. Chapter 19: Role of Magnetic Resonance Imaging in Obstetric Imaging - p. g272.e1 31. Chapter 20: Fetal Central Nervous System Imaging - p. g283 32. Chapter 21: Imaging of the Fetal Face and Neck - p. g302.e15 33. Chapter 22: Fetal Thoracic Imaging - p. g314.e1 34. Chapter 23: Fetal Cardiac Malformations and Arrhythmias: Detection, Diagnosis, Management, and Prognosis - p. g321.e6 35. Chapter 24: Fetal Abdominal Imaging - p. g365.e1 36. Chapter 25: Fetal Urogenital Imaging - p. g399.e1 37. Chapter 26: Skeletal Imaging - p. g432.e1 38. Chapter 27: Placenta and Umbilical Cord Imaging - p. g471.e1 39. Chapter 28: Uterus and Adnexae Imaging - p. g482.e8 40. Chapter 29: First-Trimester Imaging - p. g488.e1 41. Part 3: Fetal Disorders: Diagnosis and Therapy - p. g499 42. Chapter 30: Prenatal Diagnosis of Congenital Disorders - p. g499 43. Chapter 31: Teratogenesis and Environmental Exposure - p. g548.e1 44. Chapter 32: Assessment of Fetal Health - p. g559.e1 45. Chapter 33: Intrapartum Fetal Surveillance - p. g573 46. Chapter 34: Invasive Fetal Therapy - p. g594.e1 47. Chapter 35: Hemolytic Disease of the Fetus and Newborn - p. g633.e1 48. Chapter 36: Nonimmune Hydrops - p. g649.e1 49. Chapter 37: Multiple Gestation: Clinical Characteristics and Management - p. g659.e1 50. Part 4: Disorders at the Maternal-Fetal Interface - p. g685 51. Chapter 38: Prevention and Management of Preterm Parturition - p. g685 52. Chapter 39: Premature (Prelabor) Rupture of the Membranes - p. g722 53. Chapter 40: Clinical Aspects of Normal and Abnormal Labor - p. g733 54. Chapter 41: Recurrent Pregnancy Loss - p. g767 55. Chapter 42: Stillbirth - p. g781 56. Chapter 43: Placenta Previa and Accreta, Vasa Previa, Subchorionic Hemorrhage, and Abruptio Placentae - p. g798 57. Chapter 44: Fetal Growth Restriction - p. g809 58. Chapter 45: Pregnancy-Related Hypertension - p. g825 59. Part 5: Maternal Complications - p. g854 60. Chapter 46: Patient Safety and Quality Improvement in Obstetrics - p. g854 61. Chapter 47: Maternal Mortality - p. g866 62. Chapter 48: Bacterial and Parasitic Infections in Pregnancy - p. g878 63. Chapter 49: Maternal and Fetal Viral Infections - p. g907 64. Chapter 50: Sexually Transmitted Diseases - p. g937 65. Chapter 51: Maternal-Fetal Infections - p. g958 66. Chapter 52: Cardiac Diseases - p. g972.e1 67. Chapter 53: Coagulation Disorders in Pregnancy - p. g1012.e1 68. Chapter 54: Thromboembolic Disease in Pregnancy - p. g1038.e1 69. Chapter 55: Anemia and Pregnancy - p. g1053.e1 70. Chapter 56: Malignancy and Pregnancy - p. g1069.e1 71. Chapter 57: Renal Disorders - p. g1087.e1 72. Chapter 58: Respiratory Diseases in Pregnancy - p. g1105.e1 73. Chapter 59: Diabetes in Pregnancy - p. g1131 74. Chapter 60: Pregnancy in Women With Obesity - p. g1165.e1 75. Chapter 61: Thyroid Disease and Pregnancy - p. g1186.e1 76. Chapter 62: Other Endocrine Disorders of Pregnancy - p. g1213 77. Chapter 63: Gastrointestinal Disease in Pregnancy - p. g1240 78. Chapter 64: Diseases of the Liver, Biliary System, and Pancreas - p. g1256 79. Chapter 65: Pregnancy and Rheumatic Diseases - p. g1276 80. Chapter 66: Neurologic Disorders - p. g1292 81. Chapter 67: Management of Depression and Psychoses in Pregnancy and in the Puerperium - p. g1316 82. Chapter 68: Substance Use and Addiction in Pregnancy and the Postpartum Period - p. g1327 83. Chapter 69: The Skin and Pregnancy - p. g1356 84. Chapter 70: Anesthesia Considerations for Complicated Pregnancies - p. g1367 85. Chapter 71: Intensive Care Considerations in Obstetrics - p. g1386 86. Chapter 72: Pregnancy as a Window to Future Health - p. g1400 87. Part 6: The Neonate - p. g1407 88. Chapter 73: Neonatal Morbidities of Prenatal and Perinatal Origin - p. g1407 89. Index - p. g1438 90. Normal Laboratory Values in Pregnancy - p. g1438
