Cytokine Effector Functions in Tissues discusses the cytokines networks in the context of the specific-tissue environment. It is an up-to-date collection of articles that addresses the specific issue of how the cytokines are able to condition tissue specific homeostasis. The book helps the reader understand how cytokines network inside the tissues and highlights whether tissue-protection or exacerbation will be finally controlled. It describes the cytokines detected and regulated in different tissues, such as the brain, lungs, spleen, liver, pancreas and intestine, also addressing the issue of timing in specific cell types.
1. Chapter 1. Introduction to Cytokines as Tissue Regulators in Health and Disease - p. 3 2. Part II: Cytokine Tissue-Specific Regulation - p. 25 3. Chapter 2. Physiology and Pathophysiology of Adipose Tissue-Derived Cytokine Networks - p. 33 4. Chapter 3. Cytokine Networks in the Ovary - p. 51 5. Chapter 4. Cytokines in the Liver: Cytokine Mechanisms in Liver Health and Disease - p. 75 6. Part III: Cytokine Regulation in Disease - p. 89 7. Chapter 5. The Role of Adipokines and Adipogenesis in the Pathogenesis of Osteoarthritis - p. 99 8. Chapter 6. Cytokines in Atherosclerosis - p. 109 9. Chapter 7. Cytokines in Diabetes and Diabetic Complications - p. 119 10. Chapter 8. Proinflammatory and Regulatory Cytokines in Sarcoidosis - p. 129 11. Chapter 9. Cytokines and Their Implication in Axon Degeneration and Regeneration Following Peripheral Nerve Injury - p. 139 12. Chapter 10. Cytokines as Orchestrators of Skeletal Muscle Tissue Maintenance and the Inflammation Associated With Acquired Autoimmune and Hereditary Muscle Diseases - p. 149 13. Chapter 11. Airway Epithelial Cytokines in Asthma and Chronic Obstructive Pulmonary Disease - p. 163 14. Chapter 12. Eosinophil Cytokines in Allergy - p. 173 15. Chapter 13. Cytokines in Hematopoietic Stem Cell Transplantation - p. 219 16. Part IV: Cytokines and Therapeutic Applications - p. 230 17. Chapter 14. Cytokine Therapy in the Tumor Microenvironment: Old Players, New Tricks - p. 239 18. Chapter 15. Cytokines From Mesenchymal Stem Cells Induce Immunosuppressive Cells - p. 257 19. Index - p. 277
Cytokine Effector Functions in Tissues discusses the cytokines networks in the context of the specific-tissue environment. It is an up-to-date collection of articles that addresses the specific issue of how the cytokines are able to condition tissue specific homeostasis. The book helps the reader understand how cytokines network inside the tissues and highlights whether tissue-protection or exacerbation will be finally controlled. It describes the cytokines detected and regulated in different tissues, such as the brain, lungs, spleen, liver, pancreas and intestine, also addressing the issue of timing in specific cell types.
1. Chapter 1. Introduction to Cytokines as Tissue Regulators in Health and Disease - p. 3 2. Part II: Cytokine Tissue-Specific Regulation - p. 25 3. Chapter 2. Physiology and Pathophysiology of Adipose Tissue-Derived Cytokine Networks - p. 33 4. Chapter 3. Cytokine Networks in the Ovary - p. 51 5. Chapter 4. Cytokines in the Liver: Cytokine Mechanisms in Liver Health and Disease - p. 75 6. Part III: Cytokine Regulation in Disease - p. 89 7. Chapter 5. The Role of Adipokines and Adipogenesis in the Pathogenesis of Osteoarthritis - p. 99 8. Chapter 6. Cytokines in Atherosclerosis - p. 109 9. Chapter 7. Cytokines in Diabetes and Diabetic Complications - p. 119 10. Chapter 8. Proinflammatory and Regulatory Cytokines in Sarcoidosis - p. 129 11. Chapter 9. Cytokines and Their Implication in Axon Degeneration and Regeneration Following Peripheral Nerve Injury - p. 139 12. Chapter 10. Cytokines as Orchestrators of Skeletal Muscle Tissue Maintenance and the Inflammation Associated With Acquired Autoimmune and Hereditary Muscle Diseases - p. 149 13. Chapter 11. Airway Epithelial Cytokines in Asthma and Chronic Obstructive Pulmonary Disease - p. 163 14. Chapter 12. Eosinophil Cytokines in Allergy - p. 173 15. Chapter 13. Cytokines in Hematopoietic Stem Cell Transplantation - p. 219 16. Part IV: Cytokines and Therapeutic Applications - p. 230 17. Chapter 14. Cytokine Therapy in the Tumor Microenvironment: Old Players, New Tricks - p. 239 18. Chapter 15. Cytokines From Mesenchymal Stem Cells Induce Immunosuppressive Cells - p. 257 19. Index - p. 277