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Cytoskeletal Proteins in Neurodegenerative Diseases, Volume 150 covers the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disorders. The book explores the structure, function, and dynamics of key cytoskeletal components—including microtubules, actin filaments, and intermediate filaments—and examines how their dysfunction contributes to diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis (ALS). Chapters in this new release include Cytoskeletal proteins regulates Tau in Alzheimer's Disease, "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins", Glial Fibrillary Protein is potential biomarker For AD, and much more.

Additional chapters cover Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration, Cytoskeletal Proteins in Neurodegeneration, Extracellular matrix degradation proteins in Neurodegenerative disease, GPCRs regulates Cytoskeletal remodeling in microglia, Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease, Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease, Cytoskeletal Intermediate Filament proteins in Neurodegeneration, Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors, The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases, and many more timely topics.

  • Provides a detailed exploration of cytoskeletal protein families (e.g., microtubules, neurofilaments, actin) and their roles in neuronal function
  • Presents a discussion of protein aggregation, misfolding, post-translational modifications, and their impact on neuronal health
  • Examines cytoskeletal proteins as potential biomarkers for early diagnosis and disease progression

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright page - p. iv 6. Contributors - p. xvii 7. Chapter One: Cytoskeletal proteins regulates Tau protein in Alzheimer’s disease - p. 1 8. Chapter Two: Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in the (dis)function of cytoskeletal proteins - p. 29 9. Chapter Three: Actin-associated growth cone of Tau and its intracellular localization - p. 119 10. Chapter Four: Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration - p. 141 11. Chapter Five: Molecular chaperones mediated proteostasis depletion: A cause of neurodegeneration? - p. 181 12. Chapter Six: The dynamics of podosomes, extracellular matrix-associated proteins regulate the cytoskeletal remodeling, mechanosensing, migration in Tau - p. 221 13. Chapter Seven: G-protein coupled receptor regulates cytoskeletal remodelling of extracellular Tau in Alzheimer’s disease - p. 245 14. Chapter Eight: Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer’s disease - p. 285 15. Chapter Nine: G-protein coupled receptor chemokine CX3CR1 influences extracellular Tau internalization in Alzheimer’s disease - p. 319 16. Chapter Ten: Cytoskeltal intermediate filaments in Tau pathology and neurodegeneration - p. 351 17. Chapter Eleven: Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors - p. 377 18. Chapter Twelve: The quest to restore neuronal structure: Targeting cytoskeletal proteins in neurodegenerative diseases - p. 397 19. Chapter Thirteen: Pathological microtubule dynamics in Parkinson’s disease: Mechanisms and therapeutic implications - p. 423 20. Chapter Fourteen: Bioanalytical approaches applied to identify cytoskeletal proteins associated with neurodegenerative diseases - p. 445 21. Chapter Fifteen: Tau-Cytoskeleton and their interaction with other neurodegenerative proteins - p. 489 22. Chapter Sixteen: How cargo driven by kinesin motors can pass efficiently through tau islands on microtubules - p. 519

Descripcion
Descripción

Cytoskeletal Proteins in Neurodegenerative Diseases, Volume 150 covers the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disorders. The book explores the structure, function, and dynamics of key cytoskeletal components—including microtubules, actin filaments, and intermediate filaments—and examines how their dysfunction contributes to diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis (ALS). Chapters in this new release include Cytoskeletal proteins regulates Tau in Alzheimer's Disease, "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins", Glial Fibrillary Protein is potential biomarker For AD, and much more.

Additional chapters cover Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration, Cytoskeletal Proteins in Neurodegeneration, Extracellular matrix degradation proteins in Neurodegenerative disease, GPCRs regulates Cytoskeletal remodeling in microglia, Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease, Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease, Cytoskeletal Intermediate Filament proteins in Neurodegeneration, Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors, The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases, and many more timely topics.

  • Provides a detailed exploration of cytoskeletal protein families (e.g., microtubules, neurofilaments, actin) and their roles in neuronal function
  • Presents a discussion of protein aggregation, misfolding, post-translational modifications, and their impact on neuronal health
  • Examines cytoskeletal proteins as potential biomarkers for early diagnosis and disease progression

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright page - p. iv 6. Contributors - p. xvii 7. Chapter One: Cytoskeletal proteins regulates Tau protein in Alzheimer’s disease - p. 1 8. Chapter Two: Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in the (dis)function of cytoskeletal proteins - p. 29 9. Chapter Three: Actin-associated growth cone of Tau and its intracellular localization - p. 119 10. Chapter Four: Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration - p. 141 11. Chapter Five: Molecular chaperones mediated proteostasis depletion: A cause of neurodegeneration? - p. 181 12. Chapter Six: The dynamics of podosomes, extracellular matrix-associated proteins regulate the cytoskeletal remodeling, mechanosensing, migration in Tau - p. 221 13. Chapter Seven: G-protein coupled receptor regulates cytoskeletal remodelling of extracellular Tau in Alzheimer’s disease - p. 245 14. Chapter Eight: Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer’s disease - p. 285 15. Chapter Nine: G-protein coupled receptor chemokine CX3CR1 influences extracellular Tau internalization in Alzheimer’s disease - p. 319 16. Chapter Ten: Cytoskeltal intermediate filaments in Tau pathology and neurodegeneration - p. 351 17. Chapter Eleven: Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors - p. 377 18. Chapter Twelve: The quest to restore neuronal structure: Targeting cytoskeletal proteins in neurodegenerative diseases - p. 397 19. Chapter Thirteen: Pathological microtubule dynamics in Parkinson’s disease: Mechanisms and therapeutic implications - p. 423 20. Chapter Fourteen: Bioanalytical approaches applied to identify cytoskeletal proteins associated with neurodegenerative diseases - p. 445 21. Chapter Fifteen: Tau-Cytoskeleton and their interaction with other neurodegenerative proteins - p. 489 22. Chapter Sixteen: How cargo driven by kinesin motors can pass efficiently through tau islands on microtubules - p. 519

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