Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields.
1. Chapter 1 History and introduction of dendrimers - p. 1 2. Chapter 2 Design and properties of dendrimers for pharmaceutical applications - p. 15 3. Chapter 3 Magnetic properties and applications of dendrimer systems - p. 33 4. Chapter 4 Ferroelectric properties and applications of dendrimer systems - p. 49 5. Chapter 5 Biological interaction of dendrimers - p. 63 6. Chapter 6 Dendrimer nomenclature and synthesis methods - p. 75 7. Chapter 7 Types of dendrimers - p. 95 8. Chapter 8 Characterization of dendrimers - p. 125 9. Chapter 9 Safety and toxicity issues of dendrimers - p. 143 10. Chapter 10 Dendrimers and their applications in biomedicine: Dendrimer-drug interaction, a new therapeutic alternative - p. 163 11. Chapter 11 Principal concept in PEGylated dendrimer-based cancer therapeutics - p. 183 12. Chapter 12 Surface-engineered dendrimers in targeting and delivery of drugs - p. 203 13. Chapter 13 Surface engineered dendrimers as novel option for enhanced pharmaceutical and biomedical potential - p. 225 14. Chapter 14 Dendrimer hybrids with other nanoparticles as therapeutics - p. 253 15. Chapter 15 Dendrimer for solubility enhancement - p. 273 16. Chapter 16 Dendrimers for gene therapy - p. 285 17. Chapter 17 Photosensitizer-dendrimer systems in anticancer treatments: From photophysics to PDT applications - p. 311 18. Chapter 18 Dendrimers in tissue engineering - p. 327 19. Chapter 19 Dendrimer as imaging contrast agents - p. 337 20. Chapter 20 Dendrimer as antimicrobial agents - p. 363 21. Chapter 21 Multifunctional dendrimers for theranostic applications - p. 385 22. Chapter 22 Dendrimers formulations to enhance skin drug delivery - p. 399 23. Chapter 23 Dendrimers as antiinflammatory prodrugs - p. 417 24. Chapter 24 Advances in targeted dendrimers for cancer therapy and challenges for clinical translation - p. 435 25. Chapter 25 Conclusion and future considerations of dendrimers - p. 449 26. Index - p. 459
Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields.
1. Chapter 1 History and introduction of dendrimers - p. 1 2. Chapter 2 Design and properties of dendrimers for pharmaceutical applications - p. 15 3. Chapter 3 Magnetic properties and applications of dendrimer systems - p. 33 4. Chapter 4 Ferroelectric properties and applications of dendrimer systems - p. 49 5. Chapter 5 Biological interaction of dendrimers - p. 63 6. Chapter 6 Dendrimer nomenclature and synthesis methods - p. 75 7. Chapter 7 Types of dendrimers - p. 95 8. Chapter 8 Characterization of dendrimers - p. 125 9. Chapter 9 Safety and toxicity issues of dendrimers - p. 143 10. Chapter 10 Dendrimers and their applications in biomedicine: Dendrimer-drug interaction, a new therapeutic alternative - p. 163 11. Chapter 11 Principal concept in PEGylated dendrimer-based cancer therapeutics - p. 183 12. Chapter 12 Surface-engineered dendrimers in targeting and delivery of drugs - p. 203 13. Chapter 13 Surface engineered dendrimers as novel option for enhanced pharmaceutical and biomedical potential - p. 225 14. Chapter 14 Dendrimer hybrids with other nanoparticles as therapeutics - p. 253 15. Chapter 15 Dendrimer for solubility enhancement - p. 273 16. Chapter 16 Dendrimers for gene therapy - p. 285 17. Chapter 17 Photosensitizer-dendrimer systems in anticancer treatments: From photophysics to PDT applications - p. 311 18. Chapter 18 Dendrimers in tissue engineering - p. 327 19. Chapter 19 Dendrimer as imaging contrast agents - p. 337 20. Chapter 20 Dendrimer as antimicrobial agents - p. 363 21. Chapter 21 Multifunctional dendrimers for theranostic applications - p. 385 22. Chapter 22 Dendrimers formulations to enhance skin drug delivery - p. 399 23. Chapter 23 Dendrimers as antiinflammatory prodrugs - p. 417 24. Chapter 24 Advances in targeted dendrimers for cancer therapy and challenges for clinical translation - p. 435 25. Chapter 25 Conclusion and future considerations of dendrimers - p. 449 26. Index - p. 459
