This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners and trainees at all levels of experience and training. Covering all aspects of cytology, including gynecologic, nongynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cytopathology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.
Covers all areas of cytopathology, including clinical, radiologic, and immunohistochemical as well as cytopathologic features and molecular correlates where applicable
Contains new chapters on ancillary molecular tests specific to thyroid, prognostic/therapy-related immunomarkers in cell blocks, and small biopsies
Provides new immunohistochemical and molecular coverage, including new immunostains and genomic targets
Incorporates new reporting terminology (such as serous fluid and effusions) and updates to existing reporting terminologies
Reflects the expanded use of fine-needle aspiration for small biopsies (FNA-B) with many more images added and updated throughout
Keeps you up-to-date with current and emerging reporting systems on pancreaticobiliary, salivary, breast, and soft tissue cytology
Features more than 3,000 print and online images, including carefully annotated histology and gross pathology photos, full-color illustrations, clinical photographs, and radiologic images to help practicing and in-training pathologists reach a confident diagnosis
Includes new videos on such topics as the cytoprepratory process, cell transfer cell block and smears, collodion bag cell block, and more
Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert cytopathology reference at the point of care
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedications - p. v 6. Additional Contributors - p. vi 7. Preface - p. ix 8. Acknowledgments - p. xi 9. Videos - p. xi 10. List of Tables - p. xii 11. Sections - p. xiii 12. Part I: Gynecologic Cytopathology - p. 2 13. SECTION 1: OVERVIEW - p. 3 14. Chapter 1: Pap Test and Cervical Cancer Screening: History and Reporting Terminology - p. 4 15. Chapter 2: Cytopreparation, Instrumentation, and Automated Screening in Gynecologic Cytology - p. 8 16. Chapter 3: Specimen Adequacy in Cervicovaginal Cytology - p. 10 17. SECTION 2: BENIGN AND INFECTIOUS CONDITIONS - p. 13 18. Chapter 4: Normal Pap Test - p. 14 19. Chapter 5: Infectious and Other Organisms in Pap Tests - p. 16 20. Chapter 6: Nonneoplastic Findings, Mimics, and Artifacts - p. 18 21. SECTION 3: SQUAMOUS CELL ABNORMALITIES AND MIMICS - p. 27 22. Chapter 7: Low-Grade Squamous Intraepithelial Lesion and Mimics - p. 28 23. Chapter 8: High-Grade Squamous Intraepithelial Lesion and Mimics - p. 30 24. Chapter 9: Atypical Squamous Cells of Undetermined Significance - p. 34 25. Chapter 10: Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intraepithelial Lesion - p. 36 26. Chapter 11: Squamous Cell Carcinoma of Cervix, Variants and Mimics - p. 38 27. SECTION 4: GLANDULAR CELL ABNORMALITIES AND MIMICS - p. 45 28. Chapter 12: Endocervical Adenocarcinoma In Situ, Variants and Mimics - p. 46 29. Chapter 13: Endocervical Adenocarcinoma, Variants and Mimics - p. 52 30. Chapter 14: Adenocarcinoma, Gastric Type - p. 56 31. Chapter 15: Endometrial Cancers: Usual Types, Variants, and Mimics - p. 58 32. Chapter 16: Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOS - p. 64 33. Chapter 17: Endometrial Cells in Pap Test and Glandular Cells Status Post Hysterectomy - p. 70 34. SECTION 5: EXTRAUTERINE CARCINOMAS AND OTHER MALIGNANCIES OF FEMALE GENITAL TRACT - p. 73 35. Chapter 18: Extrauterine Carcinomas and Presentations in Cervicovaginal Cytology - p. 74 36. Chapter 19: Neuroendocrine Carcinoma of Cervix - p. 76 37. Chapter 20: Other Uncommon Malignancies in Cervicovaginal Cytology - p. 78 38. SECTION 6: MOLECULAR TESTING IN GYNECOLOGIC CYTOLOGY - p. 83 39. Chapter 21: HPV and Other Molecular Testing in Gynecologic Cytology - p. 84 40. SECTION 7: DIRECTLY SAMPLED ENDOMETRIAL CYTOLOGY - p. 89 41. Chapter 22: Directly Sampled Endometrial Cytology - p. 90 42. SECTION 8: ANAL CYTOLOGY - p. 95 43. Chapter 23: Anal Cytology - p. 96 44. Part II: Exfoliative Cytopathology - p. 98 45. SECTION 1: RESPIRATORY TRACT, INCLUDING LUNG FNAS - p. 99 46. Chapter 24: Specimen Types in Respiratory Cytology and Adequacy Criteria - p. 100 47. Chapter 25: Benign and Reactive Changes - p. 102 48. Chapter 26: Pneumocystis Pneumonia and Mimics - p. 106 49. Chapter 27: Fungal Organisms in Respiratory Cytology - p. 108 50. Chapter 28: Parasitic Organisms in Respiratory Cytology - p. 110 51. Chapter 29: Viral Infections (Cytomegalovirus, Herpesvirus, and Others) - p. 112 52. Chapter 30: Mycobacteria and Other Bacterial Infections - p. 114 53. Chapter 31: Sarcoidosis and Other Immune-Related Conditions - p. 116 54. Chapter 32: Pulmonary Alveolar Proteinosis and Mimics - p. 118 55. Chapter 33: Miscellaneous Findings, Including Contaminants - p. 120 56. Chapter 34: Adenocarcinoma - p. 122 57. Chapter 35: Squamous Cell Carcinoma - p. 126 58. Chapter 36: Small Cell Carcinoma - p. 128 59. Chapter 37: Large Cell Neuroendocrine Carcinoma - p. 130 60. Chapter 38: Carcinoid and Atypical Carcinoid - p. 132 61. Chapter 39: Rare Benign and Low Malignant Potential Tumors - p. 134 62. Chapter 40: Rare Malignant Tumors - p. 136 63. Chapter 41: NUT Carcinoma - p. 138 64. Chapter 42: SMARCA4-Deficient Undifferentiated Tumor - p. 139 65. Chapter 43: Pulmonary Lymphoma - p. 140 66. Chapter 44: Pulmonary Metastasis - p. 142 67. SECTION 2: GASTROINTESTINAL TRACT - p. 145 68. Chapter 45: Specimen Types in Gastrointestinal Cytology and Normal Cellular Components - p. 146 69. Chapter 46: Parasitic Infections - p. 148 70. Chapter 47: Viral Infections - p. 150 71. Chapter 48: Esophagitis and Barrett Esophagus - p. 152 72. Chapter 49: Esophageal Adenocarcinoma - p. 154 73. Chapter 50: Esophageal Squamous Cell Carcinoma - p. 156 74. Chapter 51: Gastritis and Intestinal Metaplasia - p. 158 75. Chapter 52: Gastric Adenocarcinoma - p. 160 76. Chapter 53: Gastric Lymphoma - p. 162 77. Chapter 54: Ampulla/Bile Duct/Pancreatic Duct Reactive Changes - p. 164 78. Chapter 55: Ampulla/Bile Duct/Pancreatic Duct Adenocarcinoma - p. 166 79. Chapter 56: Colorectal Adenoma/Carcinoma - p. 168 80. Chapter 57: Neuroendocrine Tumor/Carcinoma - p. 170 81. Chapter 58: Spindle Cell Neoplasms of Gastrointestinal Tract, Including Gastrointestinal Stromal Tumors - p. 172 82. SECTION 3: CEREBROSPINAL FLUID - p. 175 83. Chapter 59: Normal Cerebrospinal Fluid and Contamination by Normal Elements - p. 176 84. Chapter 60: Infectious Meningitis - p. 180 85. Chapter 61: Aseptic and Mollaret Meningitis - p. 182 86. Chapter 62: Subarachnoid Hemorrhage - p. 184 87. Chapter 63: Neurodegenerative Diseases - p. 186 88. Chapter 64: Primary Brain Tumors - p. 188 89. Chapter 65: Leukemia and Lymphoma - p. 190 90. Chapter 66: Metastasis in Cerebrospinal Fluid - p. 192 91. SECTION 4: PLEURAL, PERITONEAL, PERICARDIAL, AND PELVIC FLUID AND WASHINGS - p. 195 92. Chapter 67: Normal Cellular Components, Reactive Mesothelial Proliferations, and Reporting Terminology - p. 196 93. Chapter 68: Infectious Conditions - p. 200 94. Chapter 69: Autoimmune Diseases - p. 202 95. Chapter 70: Malignant Effusion, Mesothelioma - p. 204 96. Chapter 71: Malignant Effusion, Carcinomas - p. 208 97. Chapter 72: Malignant Effusion, Sarcomas - p. 212 98. Chapter 73: Lymphoid Effusions and Lymphomas - p. 214 99. Chapter 74: Primary Effusion Lymphoma - p. 216 100. Chapter 75: Endometriosis and Endosalpingiosis - p. 218 101. Chapter 76: Ovarian Neoplasms - p. 220 102. Chapter 77: Immunocytochemistry, Histochemistry, and Other Ancillary Techniques - p. 222 103. SECTION 5: URINARY CYTOLOGY - p. 227 104. Chapter 78: Normal Urinary Cytology, Specimen Types, and Reporting Terminology - p. 228 105. Chapter 79: Ileal Conduit Specimens - p. 232 106. Chapter 80: Noninfectious Benign Conditions - p. 234 107. Chapter 81: Infectious Benign Conditions - p. 236 108. Chapter 82: Reactive Urothelial Changes - p. 238 109. Chapter 83: Low-Grade Urothelial Lesions - p. 240 110. Chapter 84: Atypical Urothelial Cells - p. 241 111. Chapter 85: High-Grade Urothelial Dysplasia/Carcinoma/Carcinoma In Situ - p. 242 112. Chapter 86: Squamous Cell Carcinoma of Urinary Bladder - p. 244 113. Chapter 87: Adenocarcinoma of Urinary Bladder - p. 246 114. Chapter 88: Other Malignancies in Urinary Cytology - p. 248 115. Chapter 89: Renal Pelvic Cytology - p. 250 116. Chapter 90: Ancillary Testing, UroVysion, and Others - p. 252 117. Part III: Fine-Needle Aspiration, Superficial - p. 254 118. SECTION 1: OVERVIEW - p. 255 119. Chapter 91: Superficial Aspiration Technique - p. 256 120. SECTION 2: THYROID GLAND - p. 259 121. Chapter 92: Ultrasound-Guided Thyroid Fine-Needle Aspiration - p. 260 122. Chapter 93: Thyroid Fine-Needle Aspiration Reporting Terminology and Specimen Adequacy - p. 266 123. Chapter 94: Adenomatous (Benign Follicular) Nodule - p. 268 124. Chapter 95: Chronic Lymphocytic/Hashimoto Thyroiditis - p. 270 125. Chapter 96: Granulomatous Thyroiditis - p. 272 126. Chapter 97: Graves Disease/Diffuse Toxic Goiter - p. 274 127. Chapter 98: Pigmented Thyroid Lesions and Crystals - p. 275 128. Chapter 99: Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance - p. 276 129. Chapter 100: Follicular Neoplasm/Suspicious for a Follicular Neoplasm - p. 280 130. Chapter 101: Follicular Neoplasm, Oncocytic (Hürthle Cell) Type - p. 284 131. Chapter 102: Papillary Thyroid Carcinoma, Classic Subtype - p. 286 132. Chapter 103: Papillary Thyroid Carcinoma Subtypes - p. 290 133. Chapter 104: Medullary Thyroid Carcinoma - p. 298 134. Chapter 105: Poorly Differentiated Thyroid Carcinoma - p. 302 135. Chapter 106: Anaplastic Thyroid Carcinoma - p. 304 136. Chapter 107: Thyroid Lymphoma - p. 306 137. Chapter 108: Metastatic Carcinoma to Thyroid - p. 308 138. Chapter 109: Other Nonneoplastic and Neoplastic Thyroid Lesions Encountered on Thyroid FNA - p. 310 139. SECTION 3: PARATHYROID GLAND - p. 317 140. Chapter 110: Parathyroid Cyst, Adenoma, and Carcinoma - p. 318 141. SECTION 4: LYMPH NODES - p. 323 142. OVERVIEW - p. 323 143. Chapter 111: Lymph Node Aspiration: Indications, Techniques, and Reporting - p. 324 144. Chapter 112: FNA Sample Prep and Triage in Evaluating Suspected Lymphoma - p. 326 145. BENIGN, INFECTIOUS, AND REACTIVE HYPERPLASIA - p. 327 146. Chapter 113: Inflammatory and Reactive Lymphoid Hyperplasia - p. 328 147. Chapter 114: Granulomatous Lymphadenitis, Infectious and Sarcoid - p. 330 148. Chapter 115: Rosai-Dorfman Disease - p. 334 149. METASTATIC MALIGNANCIES - p. 335 150. Chapter 116: Metastatic Malignancies (Carcinoma, Melanoma) - p. 336 151. Chapter 117: HPV-Positive Head and Neck Squamous Cell Carcinoma - p. 338 152. NODAL B-CELL LYMPHOMA - p. 341 153. Chapter 118: Small Lymphocytic Lymphoma - p. 342 154. Chapter 119: Lymphoplasmacytic Lymphoma - p. 344 155. Chapter 120: Mantle Cell Lymphoma - p. 346 156. Chapter 121: Nodal Marginal Zone Lymphoma - p. 348 157. Chapter 122: Follicular Lymphoma - p. 350 158. Chapter 123: Burkitt Lymphoma - p. 352 159. Chapter 124: Large B-Cell Lymphoma - p. 354 160. EXTRANODAL B-CELL LYMPHOMA - p. 355 161. Chapter 125: Plasmacytoma - p. 356 162. Chapter 126: Mediastinal Large B-Cell Lymphoma - p. 358 163. Chapter 127: Plasmablastic Lymphoma - p. 360 164. T-CELL LYMPHOMA - p. 361 165. Chapter 128: Peripheral T-Cell Lymphoma - p. 362 166. Chapter 129: Mycosis Fungoides - p. 364 167. Chapter 130: Angioimmunoblastic Lymphoma - p. 366 168. Chapter 131: ALK(+) Anaplastic Large Cell Lymphoma - p. 368 169. Chapter 132: T-Cell Lymphoblastic Lymphoma - p. 370 170. HODGKIN LYMPHOMA - p. 371 171. Chapter 133: Nodular Lymphocyte-Predominant Hodgkin Lymphoma - p. 372 172. Chapter 134: Classic Hodgkin Lymphoma - p. 374 173. SECTION 5: SALIVARY GLAND - p. 377 174. OVERVIEW - p. 377 175. Chapter 135: Approach to Interpretation of Salivary Gland Aspiration Biopsies and Reporting Terminology (Milan System) - p. 378 176. BENIGN LESIONS - p. 381 177. Chapter 136: Normal Salivary Gland and Sialadenitis on Aspiration - p. 382 178. Chapter 137: Cysts - p. 384 179. Chapter 138: Pleomorphic Adenoma - p. 386 180. Chapter 139: Warthin Tumor - p. 388 181. Chapter 140: Myoepithelioma - p. 390 182. Chapter 141: Oncocytoma, Salivary Gland - p. 391 183. MALIGNANT NEOPLASMS - p. 391 184. Chapter 142: Adenoid Cystic Carcinoma - p. 392 185. Chapter 143: Acinic Cell Carcinoma - p. 394 186. Chapter 144: Mucoepidermoid Carcinoma - p. 396 187. Chapter 145: Basaloid Neoplasms, Benign and Malignant - p. 398 188. Chapter 146: Carcinoma Ex Pleomorphic Adenoma - p. 400 189. Chapter 147: Adenocarcinoma, NOS - p. 402 190. Chapter 148: Polymorphous Adenocarcinoma - p. 404 191. Chapter 149: Salivary Duct Carcinoma - p. 406 192. Chapter 150: Secretory Carcinoma - p. 408 193. Chapter 151: Myoepithelial Carcinoma - p. 410 194. Chapter 152: Cribriform Adenocarcinoma - p. 411 195. Chapter 153: Metastatic Carcinoma - p. 412 196. Chapter 154: Primary and Metastatic Nonepithelial Tumors - p. 414 197. SECTION 6: BREAST - p. 417 198. OVERVIEW - p. 417 199. Chapter 155: Role of Fine-Needle Aspiration of Breast, Techniques and Triple Test - p. 418 200. BENIGN BREAST LESIONS - p. 419 201. Chapter 156: Inflammatory and Granulomatous Conditions - p. 420 202. Chapter 157: Fat Necrosis - p. 422 203. Chapter 158: Nonproliferative and Proliferative Changes in Breast - p. 424 204. Chapter 159: Radial Scar/Complex Sclerosing Lesion - p. 428 205. Chapter 160: Gynecomastia - p. 430 206. Chapter 161: Mucocele-Like Lesion - p. 432 207. BENIGN NEOPLASMS - p. 433 208. Chapter 162: Fibroadenoma - p. 434 209. Chapter 163: Granular Cell Tumor of Breast - p. 438 210. Chapter 164: Papillary Neoplasms - p. 440 211. Chapter 165: Myofibroblastoma, Mammary - p. 446 212. MALIGNANT NEOPLASMS - p. 447 213. Chapter 166: Ductal Carcinoma and Variants of Invasive Mammary Carcinoma - p. 448 214. Chapter 167: Lobular Carcinoma - p. 456 215. Chapter 168: Phyllodes Tumor - p. 458 216. Chapter 169: Angiosarcoma and Other Sarcomas - p. 460 217. Chapter 170: Lymphomas and Metastatic Tumors - p. 464 218. NIPPLE DISCHARGE - p. 465 219. Chapter 171: Cytology Specimens for Risk Assessment of Breast Cancer - p. 466 220. SECTION 7: SKIN AND SUBCUTANEOUS CYTOLOGY - p. 469 221. Chapter 172: Cutaneous and Adnexal Cytology - p. 470 222. Part IV: Fine-Needle Aspiration, Deep Organs and Tissues - p. 474 223. SECTION 1: OVERVIEW - p. 475 224. Chapter 173: Techniques and Modalities of Deep Aspiration Biopsies - p. 476 225. SECTION 2: MEDIASTINUM - p. 481 226. OVERVIEW - p. 481 227. Chapter 174: Anatomic Compartments and Constituent Tumors - p. 482 228. NONNEOPLASTIC LESIONS - p. 483 229. Chapter 175: Mediastinal Cysts and Inflammatory Lesions - p. 484 230. NEOPLASMS - p. 485 231. Chapter 176: Thymoma - p. 486 232. Chapter 177: Thymic Carcinoma - p. 488 233. Chapter 178: Germ Cell Tumors - p. 490 234. Chapter 179: Neurogenic Tumors - p. 492 235. Chapter 180: Metastatic Tumors of Mediastinum - p. 494 236. SECTION 3: LIVER - p. 497 237. OVERVIEW - p. 497 238. Chapter 181: Cytology of Normal Liver - p. 498 239. Chapter 182: Inflammatory and Infectious Conditions of Liver - p. 500 240. BENIGN HEPATIC NEOPLASMS - p. 501 241. Chapter 183: Hepatocellular Adenoma - p. 502 242. Chapter 184: Focal Nodular Hyperplasia - p. 504 243. Chapter 185: Hemangioma, Liver - p. 506 244. MALIGNANT NEOPLASMS - p. 507 245. Chapter 186: Hepatocellular Carcinoma - p. 508 246. Chapter 187: Hepatoblastoma - p. 510 247. Chapter 188: Liver Metastasis - p. 512 248. SECTION 4: KIDNEY - p. 515 249. OVERVIEW - p. 515 250. Chapter 189: Cytology of Normal Kidney - p. 516 251. BENIGN LESIONS AND NEOPLASMS - p. 517 252. Chapter 190: Renal Cysts - p. 518 253. Chapter 191: Angiomyolipoma - p. 520 254. Chapter 192: Oncocytoma, Kidney - p. 522 255. Chapter 193: Metanephric Adenoma - p. 524 256. Chapter 194: Metanephric Stromal Tumor - p. 526 257. Chapter 195: Xanthogranulomatous Pyelonephritis/Malakoplakia - p. 527 258. MALIGNANT NEOPLASMS - p. 527 259. Chapter 196: Clear Cell Renal Cell Carcinoma - p. 528 260. Chapter 197: Papillary Renal Cell Carcinoma - p. 532 261. Chapter 198: Clear Cell Papillary Renal Cell Carcinoma - p. 534 262. Chapter 199: Chromophobe Renal Cell Carcinoma - p. 536 263. Chapter 200: TFE3- and TFEB-Rearranged Renal Cell Carcinomas - p. 538 264. Chapter 201: Collecting Duct Carcinoma - p. 540 265. Chapter 202: Renal Medullary Carcinoma - p. 541 266. Chapter 203: Mucinous Tubular and Spindle Cell Carcinoma of Kidney - p. 542 267. Chapter 204: Carcinoid Tumor - p. 543 268. Chapter 205: Primary Renal Sarcomas in Adults - p. 544 269. Chapter 206: Renal Lymphomas - p. 545 270. Chapter 207: Nephroblastoma (Wilms Tumor) - p. 546 271. Chapter 208: Clear Cell Sarcoma of Kidney - p. 548 272. Chapter 209: Congenital Mesoblastic Nephroma - p. 550 273. Chapter 210: Rhabdoid Tumor of Kidney - p. 552 274. Chapter 211: Metastatic Tumors to Kidney - p. 553 275. TUMORS OF RENAL PELVIS - p. 553 276. Chapter 212: Urothelial Carcinoma - p. 554 277. SECTION 5: ADRENAL GLAND - p. 557 278. OVERVIEW - p. 557 279. Chapter 213: Cytology of Normal Adrenal Gland - p. 558 280. ADRENAL CORTICAL LESIONS - p. 559 281. Chapter 214: Adrenal Cortical Adenoma - p. 560 282. Chapter 215: Adrenal Cortical Carcinoma - p. 562 283. Chapter 216: Metastatic Tumors to Adrenal Gland - p. 564 284. ADRENAL MEDULLARY LESIONS - p. 565 285. Chapter 217: Pheochromocytoma - p. 566 286. SECTION 6: PANCREAS - p. 569 287. OVERVIEW - p. 569 288. Chapter 218: Cytology of Normal Pancreas - p. 570 289. Chapter 219: Pancreaticobiliary Cytology Reporting Terminology, Cyst Evaluation - p. 572 290. NONNEOPLASTIC LESIONS - p. 573 291. Chapter 220: Pancreatitis - p. 574 292. Chapter 221: Lymphoepithelial Cyst of Pancreas - p. 576 293. Chapter 222: Intra- and Peripancreatic Splenules - p. 577 294. NEOPLASMS - p. 577 295. Chapter 223: Serous Microcystic Adenoma - p. 578 296. Chapter 224: Mucinous Cystic Neoplasm - p. 580 297. Chapter 225: Intraductal Papillary Mucinous Neoplasm - p. 582 298. Chapter 226: Solid Pseudopapillary Neoplasm - p. 584 299. Chapter 227: Pancreatic Neuroendocrine Tumor - p. 586 300. Chapter 228: Pancreatic Ductal Adenocarcinoma - p. 588 301. Chapter 229: Unusual Variants of Ductal Carcinoma - p. 590 302. Chapter 230: Acinar Cell Carcinoma - p. 594 303. Chapter 231: Lymphoma and Secondary Tumors of Pancreas - p. 596 304. SECTION 7: BONE - p. 599 305. OVERVIEW - p. 599 306. Chapter 232: Approach to Cytologic/Small Biopsy Diagnosis of Primary Bone Tumors - p. 600 307. NEOPLASMS - p. 601 308. Chapter 233: Chondromas of Bone and Soft Tissue - p. 602 309. Chapter 234: Chondroblastoma - p. 604 310. Chapter 235: Giant Cell Tumor - p. 606 311. Chapter 236: Osteoblastoma - p. 608 312. Chapter 237: Adamantinoma - p. 610 313. Chapter 238: Langerhans Cell Histiocytosis - p. 612 314. Chapter 239: Chordoma - p. 614 315. Chapter 240: Osteosarcoma - p. 616 316. Chapter 241: Chondrosarcoma - p. 620 317. Chapter 242: Ewing Sarcoma - p. 624 318. Chapter 243: Bone Lymphoma - p. 628 319. Chapter 244: Metastatic Tumors of Bone - p. 630 320. SECTION 8: SOFT TISSUE - p. 633 321. OVERVIEW - p. 633 322. Chapter 245: Approach to Cytologic/Small Biopsy Diagnosis of Primary Soft Tissue Lesions - p. 634 323. ADIPOCYTIC TUMORS - p. 635 324. Chapter 246: Benign Adipose Tissue Tumors - p. 636 325. Chapter 247: Liposarcoma - p. 638 326. FIBROBLASTIC/MYOFIBROBLASTIC LESIONS - p. 641 327. Chapter 248: Fibrosarcoma - p. 642 328. Chapter 249: Myofibroblastoma - p. 644 329. Chapter 250: Low-Grade Myofibroblastic Sarcoma - p. 646 330. FIBROHISTIOCYTIC TUMORS - p. 647 331. Chapter 251: Giant Cell Tumor of Tendon Sheath - p. 648 332. Chapter 252: Undifferentiated Pleomorphic Sarcoma - p. 650 333. TUMORS OF MUSCLE ORIGIN - p. 651 334. Chapter 253: Smooth Muscle Tumors - p. 652 335. Chapter 254: Skeletal Muscle Tumors - p. 654 336. VASCULAR TUMORS - p. 657 337. Chapter 255: Hemangioma, Soft Tissue - p. 658 338. Chapter 256: Epithelioid Hemangioendothelioma - p. 660 339. Chapter 257: Angiosarcoma - p. 662 340. OTHER TUMORS - p. 663 341. Chapter 258: Other Reactive and Neoplastic Soft Tissue Entities - p. 664 342. Chapter 259: Mesenchymal Chondrosarcoma - p. 666 343. Chapter 260: Solitary Fibrous Tumor - p. 667 344. Chapter 261: Intramuscular Myxoma - p. 668 345. Chapter 262: Synovial Sarcoma - p. 670 346. Chapter 263: Epithelioid Sarcoma - p. 672 347. Chapter 264: Alveolar Soft Part Sarcoma - p. 674 348. Chapter 265: Clear Cell Sarcoma of Soft Tissue - p. 676 349. Chapter 266: Desmoplastic Small Round Cell Tumor - p. 678 350. SECTION 9: OPHTHALMIC AND NEUROPATHOLOGY - p. 681 351. Chapter 267: Approach to Ophthalmic Cytology - p. 682 352. Chapter 268: Ophthalmic Cytopathology, Infectious - p. 686 353. Chapter 269: Ophthalmic Cytopathology, Neoplastic - p. 690 354. Chapter 270: Neuropathology Squash Preparations, Infectious - p. 696 355. Chapter 271: Neuropathology Squash Preparations, Glial Neoplasms - p. 700 356. Chapter 272: Neuropathology Squash Preparations, Nonglial Neoplasms - p. 704 357. Part V: Management and Ancillary Testing - p. 708 358. SECTION 1: CYTOPREPARATORY AND QUALITY MANAGEMENT - p. 709 359. Chapter 273: Cytopreparatory Techniques and Instrumentation in Nongynecologic Cytology - p. 710 360. Chapter 274: Quality Improvement and Laboratory Management for Cytopathology - p. 716 361. SECTION 2: ANCILLARY TESTING - p. 723 362. Chapter 275: Immunocytochemistry - p. 724 363. Chapter 276: Molecular Techniques - p. 728 364. INDEX - p. 733
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners and trainees at all levels of experience and training. Covering all aspects of cytology, including gynecologic, nongynecologic exfoliative, fine-needle aspiration, and imaging, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Cytopathology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.
Covers all areas of cytopathology, including clinical, radiologic, and immunohistochemical as well as cytopathologic features and molecular correlates where applicable
Contains new chapters on ancillary molecular tests specific to thyroid, prognostic/therapy-related immunomarkers in cell blocks, and small biopsies
Provides new immunohistochemical and molecular coverage, including new immunostains and genomic targets
Incorporates new reporting terminology (such as serous fluid and effusions) and updates to existing reporting terminologies
Reflects the expanded use of fine-needle aspiration for small biopsies (FNA-B) with many more images added and updated throughout
Keeps you up-to-date with current and emerging reporting systems on pancreaticobiliary, salivary, breast, and soft tissue cytology
Features more than 3,000 print and online images, including carefully annotated histology and gross pathology photos, full-color illustrations, clinical photographs, and radiologic images to help practicing and in-training pathologists reach a confident diagnosis
Includes new videos on such topics as the cytoprepratory process, cell transfer cell block and smears, collodion bag cell block, and more
Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert cytopathology reference at the point of care
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedications - p. v 6. Additional Contributors - p. vi 7. Preface - p. ix 8. Acknowledgments - p. xi 9. Videos - p. xi 10. List of Tables - p. xii 11. Sections - p. xiii 12. Part I: Gynecologic Cytopathology - p. 2 13. SECTION 1: OVERVIEW - p. 3 14. Chapter 1: Pap Test and Cervical Cancer Screening: History and Reporting Terminology - p. 4 15. Chapter 2: Cytopreparation, Instrumentation, and Automated Screening in Gynecologic Cytology - p. 8 16. Chapter 3: Specimen Adequacy in Cervicovaginal Cytology - p. 10 17. SECTION 2: BENIGN AND INFECTIOUS CONDITIONS - p. 13 18. Chapter 4: Normal Pap Test - p. 14 19. Chapter 5: Infectious and Other Organisms in Pap Tests - p. 16 20. Chapter 6: Nonneoplastic Findings, Mimics, and Artifacts - p. 18 21. SECTION 3: SQUAMOUS CELL ABNORMALITIES AND MIMICS - p. 27 22. Chapter 7: Low-Grade Squamous Intraepithelial Lesion and Mimics - p. 28 23. Chapter 8: High-Grade Squamous Intraepithelial Lesion and Mimics - p. 30 24. Chapter 9: Atypical Squamous Cells of Undetermined Significance - p. 34 25. Chapter 10: Atypical Squamous Cells, Cannot Rule Out High-Grade Squamous Intraepithelial Lesion - p. 36 26. Chapter 11: Squamous Cell Carcinoma of Cervix, Variants and Mimics - p. 38 27. SECTION 4: GLANDULAR CELL ABNORMALITIES AND MIMICS - p. 45 28. Chapter 12: Endocervical Adenocarcinoma In Situ, Variants and Mimics - p. 46 29. Chapter 13: Endocervical Adenocarcinoma, Variants and Mimics - p. 52 30. Chapter 14: Adenocarcinoma, Gastric Type - p. 56 31. Chapter 15: Endometrial Cancers: Usual Types, Variants, and Mimics - p. 58 32. Chapter 16: Atypical Glandular Cells: Endocervicals, Endometrials, and Glandulars, NOS - p. 64 33. Chapter 17: Endometrial Cells in Pap Test and Glandular Cells Status Post Hysterectomy - p. 70 34. SECTION 5: EXTRAUTERINE CARCINOMAS AND OTHER MALIGNANCIES OF FEMALE GENITAL TRACT - p. 73 35. Chapter 18: Extrauterine Carcinomas and Presentations in Cervicovaginal Cytology - p. 74 36. Chapter 19: Neuroendocrine Carcinoma of Cervix - p. 76 37. Chapter 20: Other Uncommon Malignancies in Cervicovaginal Cytology - p. 78 38. SECTION 6: MOLECULAR TESTING IN GYNECOLOGIC CYTOLOGY - p. 83 39. Chapter 21: HPV and Other Molecular Testing in Gynecologic Cytology - p. 84 40. SECTION 7: DIRECTLY SAMPLED ENDOMETRIAL CYTOLOGY - p. 89 41. Chapter 22: Directly Sampled Endometrial Cytology - p. 90 42. SECTION 8: ANAL CYTOLOGY - p. 95 43. Chapter 23: Anal Cytology - p. 96 44. Part II: Exfoliative Cytopathology - p. 98 45. SECTION 1: RESPIRATORY TRACT, INCLUDING LUNG FNAS - p. 99 46. Chapter 24: Specimen Types in Respiratory Cytology and Adequacy Criteria - p. 100 47. Chapter 25: Benign and Reactive Changes - p. 102 48. Chapter 26: Pneumocystis Pneumonia and Mimics - p. 106 49. Chapter 27: Fungal Organisms in Respiratory Cytology - p. 108 50. Chapter 28: Parasitic Organisms in Respiratory Cytology - p. 110 51. Chapter 29: Viral Infections (Cytomegalovirus, Herpesvirus, and Others) - p. 112 52. Chapter 30: Mycobacteria and Other Bacterial Infections - p. 114 53. Chapter 31: Sarcoidosis and Other Immune-Related Conditions - p. 116 54. Chapter 32: Pulmonary Alveolar Proteinosis and Mimics - p. 118 55. Chapter 33: Miscellaneous Findings, Including Contaminants - p. 120 56. Chapter 34: Adenocarcinoma - p. 122 57. Chapter 35: Squamous Cell Carcinoma - p. 126 58. Chapter 36: Small Cell Carcinoma - p. 128 59. Chapter 37: Large Cell Neuroendocrine Carcinoma - p. 130 60. Chapter 38: Carcinoid and Atypical Carcinoid - p. 132 61. Chapter 39: Rare Benign and Low Malignant Potential Tumors - p. 134 62. Chapter 40: Rare Malignant Tumors - p. 136 63. Chapter 41: NUT Carcinoma - p. 138 64. Chapter 42: SMARCA4-Deficient Undifferentiated Tumor - p. 139 65. Chapter 43: Pulmonary Lymphoma - p. 140 66. Chapter 44: Pulmonary Metastasis - p. 142 67. SECTION 2: GASTROINTESTINAL TRACT - p. 145 68. Chapter 45: Specimen Types in Gastrointestinal Cytology and Normal Cellular Components - p. 146 69. Chapter 46: Parasitic Infections - p. 148 70. Chapter 47: Viral Infections - p. 150 71. Chapter 48: Esophagitis and Barrett Esophagus - p. 152 72. Chapter 49: Esophageal Adenocarcinoma - p. 154 73. Chapter 50: Esophageal Squamous Cell Carcinoma - p. 156 74. Chapter 51: Gastritis and Intestinal Metaplasia - p. 158 75. Chapter 52: Gastric Adenocarcinoma - p. 160 76. Chapter 53: Gastric Lymphoma - p. 162 77. Chapter 54: Ampulla/Bile Duct/Pancreatic Duct Reactive Changes - p. 164 78. Chapter 55: Ampulla/Bile Duct/Pancreatic Duct Adenocarcinoma - p. 166 79. Chapter 56: Colorectal Adenoma/Carcinoma - p. 168 80. Chapter 57: Neuroendocrine Tumor/Carcinoma - p. 170 81. Chapter 58: Spindle Cell Neoplasms of Gastrointestinal Tract, Including Gastrointestinal Stromal Tumors - p. 172 82. SECTION 3: CEREBROSPINAL FLUID - p. 175 83. Chapter 59: Normal Cerebrospinal Fluid and Contamination by Normal Elements - p. 176 84. Chapter 60: Infectious Meningitis - p. 180 85. Chapter 61: Aseptic and Mollaret Meningitis - p. 182 86. Chapter 62: Subarachnoid Hemorrhage - p. 184 87. Chapter 63: Neurodegenerative Diseases - p. 186 88. Chapter 64: Primary Brain Tumors - p. 188 89. Chapter 65: Leukemia and Lymphoma - p. 190 90. Chapter 66: Metastasis in Cerebrospinal Fluid - p. 192 91. SECTION 4: PLEURAL, PERITONEAL, PERICARDIAL, AND PELVIC FLUID AND WASHINGS - p. 195 92. Chapter 67: Normal Cellular Components, Reactive Mesothelial Proliferations, and Reporting Terminology - p. 196 93. Chapter 68: Infectious Conditions - p. 200 94. Chapter 69: Autoimmune Diseases - p. 202 95. Chapter 70: Malignant Effusion, Mesothelioma - p. 204 96. Chapter 71: Malignant Effusion, Carcinomas - p. 208 97. Chapter 72: Malignant Effusion, Sarcomas - p. 212 98. Chapter 73: Lymphoid Effusions and Lymphomas - p. 214 99. Chapter 74: Primary Effusion Lymphoma - p. 216 100. Chapter 75: Endometriosis and Endosalpingiosis - p. 218 101. Chapter 76: Ovarian Neoplasms - p. 220 102. Chapter 77: Immunocytochemistry, Histochemistry, and Other Ancillary Techniques - p. 222 103. SECTION 5: URINARY CYTOLOGY - p. 227 104. Chapter 78: Normal Urinary Cytology, Specimen Types, and Reporting Terminology - p. 228 105. Chapter 79: Ileal Conduit Specimens - p. 232 106. Chapter 80: Noninfectious Benign Conditions - p. 234 107. Chapter 81: Infectious Benign Conditions - p. 236 108. Chapter 82: Reactive Urothelial Changes - p. 238 109. Chapter 83: Low-Grade Urothelial Lesions - p. 240 110. Chapter 84: Atypical Urothelial Cells - p. 241 111. Chapter 85: High-Grade Urothelial Dysplasia/Carcinoma/Carcinoma In Situ - p. 242 112. Chapter 86: Squamous Cell Carcinoma of Urinary Bladder - p. 244 113. Chapter 87: Adenocarcinoma of Urinary Bladder - p. 246 114. Chapter 88: Other Malignancies in Urinary Cytology - p. 248 115. Chapter 89: Renal Pelvic Cytology - p. 250 116. Chapter 90: Ancillary Testing, UroVysion, and Others - p. 252 117. Part III: Fine-Needle Aspiration, Superficial - p. 254 118. SECTION 1: OVERVIEW - p. 255 119. Chapter 91: Superficial Aspiration Technique - p. 256 120. SECTION 2: THYROID GLAND - p. 259 121. Chapter 92: Ultrasound-Guided Thyroid Fine-Needle Aspiration - p. 260 122. Chapter 93: Thyroid Fine-Needle Aspiration Reporting Terminology and Specimen Adequacy - p. 266 123. Chapter 94: Adenomatous (Benign Follicular) Nodule - p. 268 124. Chapter 95: Chronic Lymphocytic/Hashimoto Thyroiditis - p. 270 125. Chapter 96: Granulomatous Thyroiditis - p. 272 126. Chapter 97: Graves Disease/Diffuse Toxic Goiter - p. 274 127. Chapter 98: Pigmented Thyroid Lesions and Crystals - p. 275 128. Chapter 99: Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance - p. 276 129. Chapter 100: Follicular Neoplasm/Suspicious for a Follicular Neoplasm - p. 280 130. Chapter 101: Follicular Neoplasm, Oncocytic (Hürthle Cell) Type - p. 284 131. Chapter 102: Papillary Thyroid Carcinoma, Classic Subtype - p. 286 132. Chapter 103: Papillary Thyroid Carcinoma Subtypes - p. 290 133. Chapter 104: Medullary Thyroid Carcinoma - p. 298 134. Chapter 105: Poorly Differentiated Thyroid Carcinoma - p. 302 135. Chapter 106: Anaplastic Thyroid Carcinoma - p. 304 136. Chapter 107: Thyroid Lymphoma - p. 306 137. Chapter 108: Metastatic Carcinoma to Thyroid - p. 308 138. Chapter 109: Other Nonneoplastic and Neoplastic Thyroid Lesions Encountered on Thyroid FNA - p. 310 139. SECTION 3: PARATHYROID GLAND - p. 317 140. Chapter 110: Parathyroid Cyst, Adenoma, and Carcinoma - p. 318 141. SECTION 4: LYMPH NODES - p. 323 142. OVERVIEW - p. 323 143. Chapter 111: Lymph Node Aspiration: Indications, Techniques, and Reporting - p. 324 144. Chapter 112: FNA Sample Prep and Triage in Evaluating Suspected Lymphoma - p. 326 145. BENIGN, INFECTIOUS, AND REACTIVE HYPERPLASIA - p. 327 146. Chapter 113: Inflammatory and Reactive Lymphoid Hyperplasia - p. 328 147. Chapter 114: Granulomatous Lymphadenitis, Infectious and Sarcoid - p. 330 148. Chapter 115: Rosai-Dorfman Disease - p. 334 149. METASTATIC MALIGNANCIES - p. 335 150. Chapter 116: Metastatic Malignancies (Carcinoma, Melanoma) - p. 336 151. Chapter 117: HPV-Positive Head and Neck Squamous Cell Carcinoma - p. 338 152. NODAL B-CELL LYMPHOMA - p. 341 153. Chapter 118: Small Lymphocytic Lymphoma - p. 342 154. Chapter 119: Lymphoplasmacytic Lymphoma - p. 344 155. Chapter 120: Mantle Cell Lymphoma - p. 346 156. Chapter 121: Nodal Marginal Zone Lymphoma - p. 348 157. Chapter 122: Follicular Lymphoma - p. 350 158. Chapter 123: Burkitt Lymphoma - p. 352 159. Chapter 124: Large B-Cell Lymphoma - p. 354 160. EXTRANODAL B-CELL LYMPHOMA - p. 355 161. Chapter 125: Plasmacytoma - p. 356 162. Chapter 126: Mediastinal Large B-Cell Lymphoma - p. 358 163. Chapter 127: Plasmablastic Lymphoma - p. 360 164. T-CELL LYMPHOMA - p. 361 165. Chapter 128: Peripheral T-Cell Lymphoma - p. 362 166. Chapter 129: Mycosis Fungoides - p. 364 167. Chapter 130: Angioimmunoblastic Lymphoma - p. 366 168. Chapter 131: ALK(+) Anaplastic Large Cell Lymphoma - p. 368 169. Chapter 132: T-Cell Lymphoblastic Lymphoma - p. 370 170. HODGKIN LYMPHOMA - p. 371 171. Chapter 133: Nodular Lymphocyte-Predominant Hodgkin Lymphoma - p. 372 172. Chapter 134: Classic Hodgkin Lymphoma - p. 374 173. SECTION 5: SALIVARY GLAND - p. 377 174. OVERVIEW - p. 377 175. Chapter 135: Approach to Interpretation of Salivary Gland Aspiration Biopsies and Reporting Terminology (Milan System) - p. 378 176. BENIGN LESIONS - p. 381 177. Chapter 136: Normal Salivary Gland and Sialadenitis on Aspiration - p. 382 178. Chapter 137: Cysts - p. 384 179. Chapter 138: Pleomorphic Adenoma - p. 386 180. Chapter 139: Warthin Tumor - p. 388 181. Chapter 140: Myoepithelioma - p. 390 182. Chapter 141: Oncocytoma, Salivary Gland - p. 391 183. MALIGNANT NEOPLASMS - p. 391 184. Chapter 142: Adenoid Cystic Carcinoma - p. 392 185. Chapter 143: Acinic Cell Carcinoma - p. 394 186. Chapter 144: Mucoepidermoid Carcinoma - p. 396 187. Chapter 145: Basaloid Neoplasms, Benign and Malignant - p. 398 188. Chapter 146: Carcinoma Ex Pleomorphic Adenoma - p. 400 189. Chapter 147: Adenocarcinoma, NOS - p. 402 190. Chapter 148: Polymorphous Adenocarcinoma - p. 404 191. Chapter 149: Salivary Duct Carcinoma - p. 406 192. Chapter 150: Secretory Carcinoma - p. 408 193. Chapter 151: Myoepithelial Carcinoma - p. 410 194. Chapter 152: Cribriform Adenocarcinoma - p. 411 195. Chapter 153: Metastatic Carcinoma - p. 412 196. Chapter 154: Primary and Metastatic Nonepithelial Tumors - p. 414 197. SECTION 6: BREAST - p. 417 198. OVERVIEW - p. 417 199. Chapter 155: Role of Fine-Needle Aspiration of Breast, Techniques and Triple Test - p. 418 200. BENIGN BREAST LESIONS - p. 419 201. Chapter 156: Inflammatory and Granulomatous Conditions - p. 420 202. Chapter 157: Fat Necrosis - p. 422 203. Chapter 158: Nonproliferative and Proliferative Changes in Breast - p. 424 204. Chapter 159: Radial Scar/Complex Sclerosing Lesion - p. 428 205. Chapter 160: Gynecomastia - p. 430 206. Chapter 161: Mucocele-Like Lesion - p. 432 207. BENIGN NEOPLASMS - p. 433 208. Chapter 162: Fibroadenoma - p. 434 209. Chapter 163: Granular Cell Tumor of Breast - p. 438 210. Chapter 164: Papillary Neoplasms - p. 440 211. Chapter 165: Myofibroblastoma, Mammary - p. 446 212. MALIGNANT NEOPLASMS - p. 447 213. Chapter 166: Ductal Carcinoma and Variants of Invasive Mammary Carcinoma - p. 448 214. Chapter 167: Lobular Carcinoma - p. 456 215. Chapter 168: Phyllodes Tumor - p. 458 216. Chapter 169: Angiosarcoma and Other Sarcomas - p. 460 217. Chapter 170: Lymphomas and Metastatic Tumors - p. 464 218. NIPPLE DISCHARGE - p. 465 219. Chapter 171: Cytology Specimens for Risk Assessment of Breast Cancer - p. 466 220. SECTION 7: SKIN AND SUBCUTANEOUS CYTOLOGY - p. 469 221. Chapter 172: Cutaneous and Adnexal Cytology - p. 470 222. Part IV: Fine-Needle Aspiration, Deep Organs and Tissues - p. 474 223. SECTION 1: OVERVIEW - p. 475 224. Chapter 173: Techniques and Modalities of Deep Aspiration Biopsies - p. 476 225. SECTION 2: MEDIASTINUM - p. 481 226. OVERVIEW - p. 481 227. Chapter 174: Anatomic Compartments and Constituent Tumors - p. 482 228. NONNEOPLASTIC LESIONS - p. 483 229. Chapter 175: Mediastinal Cysts and Inflammatory Lesions - p. 484 230. NEOPLASMS - p. 485 231. Chapter 176: Thymoma - p. 486 232. Chapter 177: Thymic Carcinoma - p. 488 233. Chapter 178: Germ Cell Tumors - p. 490 234. Chapter 179: Neurogenic Tumors - p. 492 235. Chapter 180: Metastatic Tumors of Mediastinum - p. 494 236. SECTION 3: LIVER - p. 497 237. OVERVIEW - p. 497 238. Chapter 181: Cytology of Normal Liver - p. 498 239. Chapter 182: Inflammatory and Infectious Conditions of Liver - p. 500 240. BENIGN HEPATIC NEOPLASMS - p. 501 241. Chapter 183: Hepatocellular Adenoma - p. 502 242. Chapter 184: Focal Nodular Hyperplasia - p. 504 243. Chapter 185: Hemangioma, Liver - p. 506 244. MALIGNANT NEOPLASMS - p. 507 245. Chapter 186: Hepatocellular Carcinoma - p. 508 246. Chapter 187: Hepatoblastoma - p. 510 247. Chapter 188: Liver Metastasis - p. 512 248. SECTION 4: KIDNEY - p. 515 249. OVERVIEW - p. 515 250. Chapter 189: Cytology of Normal Kidney - p. 516 251. BENIGN LESIONS AND NEOPLASMS - p. 517 252. Chapter 190: Renal Cysts - p. 518 253. Chapter 191: Angiomyolipoma - p. 520 254. Chapter 192: Oncocytoma, Kidney - p. 522 255. Chapter 193: Metanephric Adenoma - p. 524 256. Chapter 194: Metanephric Stromal Tumor - p. 526 257. Chapter 195: Xanthogranulomatous Pyelonephritis/Malakoplakia - p. 527 258. MALIGNANT NEOPLASMS - p. 527 259. Chapter 196: Clear Cell Renal Cell Carcinoma - p. 528 260. Chapter 197: Papillary Renal Cell Carcinoma - p. 532 261. Chapter 198: Clear Cell Papillary Renal Cell Carcinoma - p. 534 262. Chapter 199: Chromophobe Renal Cell Carcinoma - p. 536 263. Chapter 200: TFE3- and TFEB-Rearranged Renal Cell Carcinomas - p. 538 264. Chapter 201: Collecting Duct Carcinoma - p. 540 265. Chapter 202: Renal Medullary Carcinoma - p. 541 266. Chapter 203: Mucinous Tubular and Spindle Cell Carcinoma of Kidney - p. 542 267. Chapter 204: Carcinoid Tumor - p. 543 268. Chapter 205: Primary Renal Sarcomas in Adults - p. 544 269. Chapter 206: Renal Lymphomas - p. 545 270. Chapter 207: Nephroblastoma (Wilms Tumor) - p. 546 271. Chapter 208: Clear Cell Sarcoma of Kidney - p. 548 272. Chapter 209: Congenital Mesoblastic Nephroma - p. 550 273. Chapter 210: Rhabdoid Tumor of Kidney - p. 552 274. Chapter 211: Metastatic Tumors to Kidney - p. 553 275. TUMORS OF RENAL PELVIS - p. 553 276. Chapter 212: Urothelial Carcinoma - p. 554 277. SECTION 5: ADRENAL GLAND - p. 557 278. OVERVIEW - p. 557 279. Chapter 213: Cytology of Normal Adrenal Gland - p. 558 280. ADRENAL CORTICAL LESIONS - p. 559 281. Chapter 214: Adrenal Cortical Adenoma - p. 560 282. Chapter 215: Adrenal Cortical Carcinoma - p. 562 283. Chapter 216: Metastatic Tumors to Adrenal Gland - p. 564 284. ADRENAL MEDULLARY LESIONS - p. 565 285. Chapter 217: Pheochromocytoma - p. 566 286. SECTION 6: PANCREAS - p. 569 287. OVERVIEW - p. 569 288. Chapter 218: Cytology of Normal Pancreas - p. 570 289. Chapter 219: Pancreaticobiliary Cytology Reporting Terminology, Cyst Evaluation - p. 572 290. NONNEOPLASTIC LESIONS - p. 573 291. Chapter 220: Pancreatitis - p. 574 292. Chapter 221: Lymphoepithelial Cyst of Pancreas - p. 576 293. Chapter 222: Intra- and Peripancreatic Splenules - p. 577 294. NEOPLASMS - p. 577 295. Chapter 223: Serous Microcystic Adenoma - p. 578 296. Chapter 224: Mucinous Cystic Neoplasm - p. 580 297. Chapter 225: Intraductal Papillary Mucinous Neoplasm - p. 582 298. Chapter 226: Solid Pseudopapillary Neoplasm - p. 584 299. Chapter 227: Pancreatic Neuroendocrine Tumor - p. 586 300. Chapter 228: Pancreatic Ductal Adenocarcinoma - p. 588 301. Chapter 229: Unusual Variants of Ductal Carcinoma - p. 590 302. Chapter 230: Acinar Cell Carcinoma - p. 594 303. Chapter 231: Lymphoma and Secondary Tumors of Pancreas - p. 596 304. SECTION 7: BONE - p. 599 305. OVERVIEW - p. 599 306. Chapter 232: Approach to Cytologic/Small Biopsy Diagnosis of Primary Bone Tumors - p. 600 307. NEOPLASMS - p. 601 308. Chapter 233: Chondromas of Bone and Soft Tissue - p. 602 309. Chapter 234: Chondroblastoma - p. 604 310. Chapter 235: Giant Cell Tumor - p. 606 311. Chapter 236: Osteoblastoma - p. 608 312. Chapter 237: Adamantinoma - p. 610 313. Chapter 238: Langerhans Cell Histiocytosis - p. 612 314. Chapter 239: Chordoma - p. 614 315. Chapter 240: Osteosarcoma - p. 616 316. Chapter 241: Chondrosarcoma - p. 620 317. Chapter 242: Ewing Sarcoma - p. 624 318. Chapter 243: Bone Lymphoma - p. 628 319. Chapter 244: Metastatic Tumors of Bone - p. 630 320. SECTION 8: SOFT TISSUE - p. 633 321. OVERVIEW - p. 633 322. Chapter 245: Approach to Cytologic/Small Biopsy Diagnosis of Primary Soft Tissue Lesions - p. 634 323. ADIPOCYTIC TUMORS - p. 635 324. Chapter 246: Benign Adipose Tissue Tumors - p. 636 325. Chapter 247: Liposarcoma - p. 638 326. FIBROBLASTIC/MYOFIBROBLASTIC LESIONS - p. 641 327. Chapter 248: Fibrosarcoma - p. 642 328. Chapter 249: Myofibroblastoma - p. 644 329. Chapter 250: Low-Grade Myofibroblastic Sarcoma - p. 646 330. FIBROHISTIOCYTIC TUMORS - p. 647 331. Chapter 251: Giant Cell Tumor of Tendon Sheath - p. 648 332. Chapter 252: Undifferentiated Pleomorphic Sarcoma - p. 650 333. TUMORS OF MUSCLE ORIGIN - p. 651 334. Chapter 253: Smooth Muscle Tumors - p. 652 335. Chapter 254: Skeletal Muscle Tumors - p. 654 336. VASCULAR TUMORS - p. 657 337. Chapter 255: Hemangioma, Soft Tissue - p. 658 338. Chapter 256: Epithelioid Hemangioendothelioma - p. 660 339. Chapter 257: Angiosarcoma - p. 662 340. OTHER TUMORS - p. 663 341. Chapter 258: Other Reactive and Neoplastic Soft Tissue Entities - p. 664 342. Chapter 259: Mesenchymal Chondrosarcoma - p. 666 343. Chapter 260: Solitary Fibrous Tumor - p. 667 344. Chapter 261: Intramuscular Myxoma - p. 668 345. Chapter 262: Synovial Sarcoma - p. 670 346. Chapter 263: Epithelioid Sarcoma - p. 672 347. Chapter 264: Alveolar Soft Part Sarcoma - p. 674 348. Chapter 265: Clear Cell Sarcoma of Soft Tissue - p. 676 349. Chapter 266: Desmoplastic Small Round Cell Tumor - p. 678 350. SECTION 9: OPHTHALMIC AND NEUROPATHOLOGY - p. 681 351. Chapter 267: Approach to Ophthalmic Cytology - p. 682 352. Chapter 268: Ophthalmic Cytopathology, Infectious - p. 686 353. Chapter 269: Ophthalmic Cytopathology, Neoplastic - p. 690 354. Chapter 270: Neuropathology Squash Preparations, Infectious - p. 696 355. Chapter 271: Neuropathology Squash Preparations, Glial Neoplasms - p. 700 356. Chapter 272: Neuropathology Squash Preparations, Nonglial Neoplasms - p. 704 357. Part V: Management and Ancillary Testing - p. 708 358. SECTION 1: CYTOPREPARATORY AND QUALITY MANAGEMENT - p. 709 359. Chapter 273: Cytopreparatory Techniques and Instrumentation in Nongynecologic Cytology - p. 710 360. Chapter 274: Quality Improvement and Laboratory Management for Cytopathology - p. 716 361. SECTION 2: ANCILLARY TESTING - p. 723 362. Chapter 275: Immunocytochemistry - p. 724 363. Chapter 276: Molecular Techniques - p. 728 364. INDEX - p. 733
