This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering a broad array of cutaneous neoplasms and their differential diagnoses, it incorporates the most recent clinical, pathological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Succinctly written, richly illustrated, and easy to use, Diagnostic Pathology: Neoplastic Dermatopathology, fourth edition, is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource.
1. Cover Image - p. Cover 2. Title Page - p. ii 3. Table of Contents - p. iii 4. Contributing Authors - p. iv 5. Copyright - p. v 6. Dedications - p. v 7. Additional Contributors - p. vii 8. Preface - p. vii 9. Acknowledgments - p. viii 10. Sections - p. xi 11. List of Tables - p. xiii 12. Part I: Melanocytic Tumors of Skin - p. 1 13. Section 1: Benign Melanocytic Tumors (Nevi) - p. 1 14. Chapter 1: Congenital Melanocytic Nevi - p. 1 15. Chapter 2: Common Acquired Melanocytic Nevi - p. 5 16. Chapter 3: Common Blue Nevi - p. 9 17. Chapter 4: Cellular Blue Nevi - p. 13 18. Chapter 5: Combined Nevi - p. 17 19. Chapter 6: Halo Nevi - p. 19 20. Chapter 7: Nevi of Special Sites - p. 21 21. Chapter 8: Deep Penetrating/Inverted Type A Nevi - p. 25 22. Chapter 9: Conjunctival Melanocytic Nevi - p. 29 23. Chapter 10: Dermal Melanocytosis: Acquired and Congenital - p. 33 24. Chapter 11: Atypical/Dysplastic Melanocytic Nevi - p. 35 25. Chapter 12: Spitz (Spindle and Epithelioid Cell) Nevi - p. 39 26. Chapter 13: Pigmented Spindle Cell Nevi (Reed Nevi) - p. 45 27. Chapter 14: BAP1-Inactivated Melanocytoma - p. 49 28. Section 2: Malignant Tumors (Melanomas and Related Lesions) - p. 53 29. Melanoma In Situ - p. 53 30. Chapter 15: Melanoma In Situ, Lentigo Maligna Type - p. 53 31. Chapter 16: Melanoma In Situ, Superficial Spreading Type - p. 59 32. Chapter 17: Melanoma In Situ, Not Otherwise Specified - p. 63 33. Invasive Melanoma - p. 67 34. Chapter 18: Melanoma in Childhood - p. 67 35. Chapter 19: Atypical/Borderline and Malignant Spitz Tumors - p. 71 36. Chapter 20: Melanoma, Lentigo Maligna Type - p. 77 37. Chapter 21: Melanoma, Superficial Spreading Type - p. 81 38. Chapter 22: Melanoma, Nodular Type - p. 85 39. Chapter 23: Melanoma, Desmoplastic Type - p. 89 40. Chapter 24: Melanoma, Nevoid Type - p. 95 41. Chapter 25: Melanoma, Acral Type - p. 99 42. Chapter 26: Melanoma, Oral Type - p. 103 43. Chapter 27: Melanoma, Mucosal (Genital) Type - p. 107 44. Chapter 28: Melanoma, Sinonasal Mucosal Type - p. 111 45. Chapter 29: Melanoma, Conjunctival Type - p. 117 46. Chapter 30: Malignant Cellular Blue Nevus (Melanoma Arising in or Mimicking Cellular Blue Nevus) - p. 121 47. Chapter 31: Pigmented Epithelioid Melanocytoma - p. 125 48. Chapter 32: Melanoma, Primary Dermal Type - p. 129 49. Chapter 33: Melanoma, Other Unusual and Rare Variants - p. 131 50. Chapter 34: Staging for Specimens of Malignant Melanoma of Skin - p. 135 51. Part II: Nonmelanocytic Tumors of Skin - p. 139 52. Section 1: Epithelial Cysts - p. 139 53. Chapter 35: Epidermoid/Epidermal Inclusion Cyst - p. 139 54. Chapter 36: Pilar (Trichilemmal) Cyst - p. 143 55. Chapter 37: Proliferating Pilar (Trichilemmal) Cyst/Tumor - p. 145 56. Chapter 38: HPV-Related Epidermal Cyst - p. 149 57. Chapter 39: Vellus Hair Cyst - p. 151 58. Chapter 40: Steatocystoma (Multiplex) - p. 153 59. Chapter 41: Cutaneous Keratocyst - p. 155 60. Chapter 42: Milium - p. 157 61. Chapter 43: Hidrocystoma (Apocrine and Eccrine) - p. 159 62. Chapter 44: Digital Mucous Cyst - p. 161 63. Chapter 45: Bronchogenic Cyst - p. 163 64. Chapter 46: Branchial Cleft Cyst - p. 165 65. Chapter 47: Median Raphe Cyst - p. 171 66. Chapter 48: Cutaneous Ciliated Cyst - p. 173 67. Section 2: Epidermal Tumors - p. 175 68. Benign Epidermal Tumors and Proliferative Lesions - p. 175 69. Chapter 49: Epidermal Nevus - p. 175 70. Chapter 50: Seborrheic Keratosis (and Variants) - p. 181 71. Chapter 51: Pseudoepitheliomatous Hyperplasia - p. 187 72. Chapter 52: Warty Dyskeratoma - p. 189 73. Chapter 53: Acantholytic and Acantholytic Dyskeratotic Acanthoma - p. 193 74. Chapter 54: Verruca Vulgaris (and Variants) - p. 195 75. Chapter 55: Condyloma Acuminatum (Genital Wart) - p. 199 76. Chapter 56: Prurigo Nodularis - p. 203 77. Chapter 57: Large Cell Acanthoma - p. 205 78. Chapter 58: Clear Cell Acanthoma - p. 207 79. Chapter 59: Clear Cell Papulosis - p. 209 80. Chapter 60: Toker Cell Hyperplasia - p. 211 81. Chapter 61: Porokeratosis - p. 213 82. Premalignant and Malignant Epidermal Tumors - p. 217 83. Chapter 62: Actinic Keratosis - p. 217 84. Chapter 63: Actinic Cheilitis - p. 221 85. Chapter 64: Squamous Cell Carcinoma In Situ (Bowen Disease) - p. 223 86. Chapter 65: Bowenoid Papulosis - p. 227 87. Chapter 66: Penile and Vulvar Intraepithelial Neoplasia - p. 229 88. Chapter 67: Epidermodysplasia Verruciformis - p. 233 89. Chapter 68: Verrucous Carcinoma (and Variants) - p. 235 90. Chapter 69: Squamous Cell Carcinoma (and Variants) - p. 241 91. Chapter 70: Keratoacanthoma - p. 247 92. Chapter 71: Lymphoepithelioma-Like Carcinoma of Skin - p. 251 93. Chapter 72: Basal Cell Carcinoma - p. 253 94. Chapter 73: Extramammary Paget Disease - p. 259 95. Chapter 74: Squamomelanocytic Tumor - p. 263 96. Chapter 75: Staging for Specimens of Squamous Cell Carcinoma of Skin - p. 265 97. Section 3: Tumors and Tumor-Like Conditions of Hair Follicle - p. 267 98. Chapter 76: Nevus Sebaceus and Follicular Hamartomas - p. 267 99. Chapter 77: Trichofolliculoma - p. 273 100. Chapter 78: Trichoadenoma - p. 275 101. Chapter 79: Trichoepithelioma - p. 277 102. Chapter 80: Trichoblastoma and Trichoblastic Carcinoma - p. 281 103. Chapter 81: Panfolliculoma - p. 285 104. Chapter 82: Tumor of Follicular Infundibulum - p. 287 105. Chapter 83: Dilated Pore of Winer - p. 289 106. Chapter 84: Pilar Sheath Acanthoma - p. 291 107. Chapter 85: Inverted Follicular Keratosis - p. 293 108. Chapter 86: Trichilemmoma - p. 295 109. Chapter 87: Trichilemmal Carcinoma - p. 299 110. Chapter 88: Pilomatrixoma and Pilomatrical Carcinoma - p. 301 111. Chapter 89: Fibrofolliculoma and Trichodiscoma - p. 305 112. Section 4: Tumors and Tumor-Like Conditions with Sebaceous Differentiation - p. 307 113. Chapter 90: Sebaceous Hyperplasia - p. 307 114. Chapter 91: Superficial Epithelioma with Sebaceous Differentiation - p. 311 115. Chapter 92: Sebaceoma (Sebaceous Epithelioma) - p. 313 116. Chapter 93: Sebaceous Adenoma - p. 317 117. Chapter 94: Sebaceous Carcinoma - p. 319 118. Section 5: Neoplasms and Proliferations of Eccrine and Apocrine Sweat Glands - p. 325 119. Chapter 95: Tubular Apocrine Adenoma - p. 325 120. Chapter 96: Syringocystadenoma Papilliferum - p. 329 121. Chapter 97: Hidradenoma Papilliferum - p. 333 122. Chapter 98: Hidradenoma - p. 335 123. Chapter 99: Hidradenocarcinoma - p. 339 124. Chapter 100: Poroma and Dermal Duct Tumor - p. 343 125. Chapter 101: Porocarcinoma - p. 347 126. Chapter 102: Cylindroma and Cylindrocarcinoma - p. 349 127. Chapter 103: Spiradenoma and Spiradenocarcinoma - p. 355 128. Chapter 104: Adenoid Cystic Carcinoma - p. 359 129. Chapter 105: Primary Cutaneous Endocrine Mucin-Producing Carcinoma - p. 361 130. Chapter 106: Primary Cutaneous Mucinous Carcinoma - p. 363 131. Chapter 107: Apocrine Carcinoma (Apocrine Adenocarcinoma) - p. 367 132. Chapter 108: Digital Papillary Adenocarcinoma - p. 369 133. Chapter 109: Eccrine Hamartomas - p. 373 134. Chapter 110: Papillary Eccrine Adenoma - p. 375 135. Chapter 111: Syringoma - p. 377 136. Chapter 112: Syringofibroadenoma - p. 379 137. Chapter 113: Eccrine Carcinoma - p. 381 138. Chapter 114: Squamoid Eccrine Ductal Carcinoma - p. 383 139. Chapter 115: Microcystic Adnexal Carcinoma - p. 385 140. Chapter 116: Cutaneous Mixed Tumor (Chondroid Syringoma) - p. 389 141. Chapter 117: Malignant Mixed Tumor - p. 393 142. Section 6: Nail Tumors - p. 395 143. Chapter 118: Onychomatricoma - p. 395 144. Chapter 119: Onychopapilloma - p. 399 145. Chapter 120: Onychocytic Matricoma - p. 401 146. Section 7: Metastatic Tumors - p. 403 147. Chapter 121: Metastatic Skin Tumors - p. 403 148. Chapter 122: Metastatic Tumors to Skin - p. 409 149. Section 8: Fibrous and “Fibrohistiocytic” Tissue Tumors - p. 415 150. Benign Fibrous and “Fibrohistiocytic” Tissue Tumors - p. 415 151. Chapter 123: Fibroepithelial Polyp (Acrochordon) - p. 415 152. Chapter 124: Keloids and Hypertrophic Scars - p. 419 153. Chapter 125: Desmoplastic Fibroblastoma - p. 421 154. Chapter 126: Pleomorphic Fibroma - p. 423 155. Chapter 127: Sclerotic Fibroma - p. 425 156. Chapter 128: Fibromatosis - p. 427 157. Chapter 129: Juvenile Hyaline Fibromatosis - p. 433 158. Chapter 130: Angiofibroma and Related Lesions - p. 435 159. Chapter 131: Acral Fibrokeratoma - p. 437 160. Chapter 132: Dermatofibroma and Fibrous Histiocytoma - p. 439 161. Chapter 133: Epithelioid Cell Histiocytoma - p. 445 162. Chapter 134: Dermatomyofibroma - p. 447 163. Chapter 135: Fibrous Hamartoma of Infancy - p. 449 164. Chapter 136: Inclusion Body Fibromatosis - p. 455 165. Chapter 137: Angiomyofibroblastoma - p. 459 166. Chapter 138: Multinucleate Cell Angiohistiocytoma - p. 463 167. Chapter 139: Localized-Type Tenosynovial Giant Cell Tumor - p. 465 168. Chapter 140: Myofibroma and Myofibromatosis - p. 471 169. Chapter 141: Cutaneous Myxoma and Angiomyxoma - p. 475 170. Chapter 142: Acral Fibromyxoma - p. 477 171. Chapter 143: Pseudosarcomatous Fibroblastic Proliferations - p. 481 172. Atypical and Malignant Fibrous and “Fibrohistiocytic” Tissue Tumors - p. 489 173. Chapter 144: Angiomatoid Fibrous Histiocytoma - p. 489 174. Chapter 145: Plexiform Fibrohistiocytic Tumor - p. 497 175. Chapter 146: Dermatofibrosarcoma Protuberans - p. 501 176. Chapter 147: Atypical Fibroxanthoma - p. 507 177. Chapter 148: Pleomorphic (Dermal) Sarcoma - p. 513 178. Chapter 149: Adult-Type Fibrosarcoma - p. 515 179. Chapter 150: Myxofibrosarcoma - p. 517 180. Chapter 151: Superficial Low-Grade Fibromyxoid Sarcoma - p. 521 181. Chapter 152: Myxoinflammatory Fibroblastic Sarcoma - p. 523 182. Chapter 153: Superficial CD34 (+) Fibroblastic Tumor - p. 531 183. Chapter 154: EWSR1::SMAD3 Fibroblastic Tumor - p. 535 184. Section 9: Vascular and Perivascular Tumors and Pseudotumors - p. 539 185. Chapter 155: Vascular Malformations - p. 539 186. Chapter 156: Arteriovenous Tumor - p. 545 187. Chapter 157: Capillary Hemangioma - p. 547 188. Chapter 158: Venous Malformations - p. 549 189. Chapter 159: Infantile and Congenital Hemangiomas - p. 553 190. Chapter 160: Sinusoidal Hemangioma - p. 557 191. Chapter 161: Tufted Angioma - p. 559 192. Chapter 162: Glomeruloid Hemangioma - p. 561 193. Chapter 163: Angiolymphoid Hyperplasia with Eosinophilia - p. 563 194. Chapter 164: Hobnail (Targetoid Hemosiderotic) Hemangioma - p. 565 195. Chapter 165: Spindle Cell Hemangioma - p. 567 196. Chapter 166: Microvenular Hemangioma - p. 569 197. Chapter 167: Verrucous Venous Malformation - p. 571 198. Chapter 168: Angiokeratoma - p. 573 199. Chapter 169: Venous Lake - p. 575 200. Chapter 170: Papillary Endothelial Hyperplasia (Masson Tumor) - p. 577 201. Chapter 171: Glomus Tumors - p. 579 202. Chapter 172: Lymphatic Malformation - p. 585 203. Chapter 173: Progressive Lymphangioma - p. 589 204. Chapter 174: Bacillary Angiomatosis - p. 591 205. Chapter 175: Kaposi Sarcoma - p. 593 206. Chapter 176: Kaposiform Hemangioendothelioma - p. 601 207. Chapter 177: Epithelioid Hemangioendothelioma - p. 603 208. Chapter 178: Retiform Hemangioendothelioma - p. 609 209. Chapter 179: Papillary Intralymphatic Angioendothelioma - p. 611 210. Chapter 180: Atypical Vascular Lesion - p. 613 211. Chapter 181: Angiosarcoma - p. 615 212. Section 10: Tumors and Tumor-Like Conditions with Neural, Nerve Sheath, and Neuroendocrine Differentiation - p. 621 213. Chapter 182: Neuromas - p. 621 214. Chapter 183: Neurofibroma - p. 627 215. Chapter 184: Schwannoma - p. 637 216. Chapter 185: Dermal Nerve Sheath Myxoma - p. 651 217. Chapter 186: Granular Cell Tumor - p. 655 218. Chapter 187: Lipomatosis of Nerve - p. 661 219. Chapter 188: Perineurioma - p. 663 220. Chapter 189: Nasal Glial Heterotopia - p. 667 221. Chapter 190: Ectopic Meningioma and Meningothelial Hamartoma - p. 669 222. Chapter 191: Superficial Malignant Peripheral Nerve Sheath Tumor - p. 671 223. Chapter 192: Superficial Ewing Sarcoma - p. 675 224. Chapter 193: Primary Neuroendocrine (Merkel Cell) Carcinoma - p. 679 225. Section 11: Tumors of Muscle, Fat, Cartilage, and Bone - p. 683 226. Chapter 194: Congenital Smooth Muscle Hamartoma - p. 683 227. Chapter 195: Leiomyoma (Pilar) - p. 687 228. Chapter 196: Angioleiomyoma - p. 691 229. Chapter 197: Leiomyosarcoma - p. 693 230. Chapter 198: Rhabdomyoma - p. 697 231. Chapter 199: Cutaneous Rhabdomyosarcoma - p. 701 232. Chapter 200: Lipoma - p. 705 233. Chapter 201: Angiolipoma - p. 711 234. Chapter 202: Spindle Cell/Pleomorphic Lipoma - p. 715 235. Chapter 203: Chondroid Lipoma - p. 721 236. Chapter 204: Nevus Lipomatosus - p. 725 237. Chapter 205: Hibernoma - p. 727 238. Chapter 206: Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma - p. 731 239. Chapter 207: Soft Tissue Chondroma - p. 737 240. Chapter 208: Osteoma Cutis - p. 743 241. Section 12: Histiocytic Proliferations - p. 745 242. Chapter 209: Juvenile and Adult-Type Xanthogranuloma - p. 745 243. Chapter 210: Reticulohistiocytoma - p. 751 244. Chapter 211: Multicentric Reticulohistiocytosis - p. 755 245. Chapter 212: Langerhans Cell Histiocytosis - p. 757 246. Chapter 213: Non-Langerhans Cell Histiocytoses - p. 761 247. Chapter 214: Rosai-Dorfman Disease - p. 769 248. Chapter 215: Histiocytic Sarcoma - p. 775 249. Chapter 216: Polyvinylpyrrolidone Storage Disease - p. 779 250. Chapter 217: Xanthomas - p. 781 251. Chapter 218: Verruciform Xanthoma - p. 785 252. Section 13: Lymphomas and Hematopoietic Proliferations - p. 787 253. B-Cell Neoplasms - p. 787 254. Chapter 219: Cutaneous Plasmacytoma - p. 787 255. Chapter 220: Primary Cutaneous Marginal Zone Lymphoma - p. 793 256. Chapter 221: Primary Cutaneous Follicle Center Lymphoma - p. 799 257. Chapter 222: Diffuse Large B-Cell Lymphoma, Leg Type - p. 805 258. Chapter 223: Lymphomatoid Granulomatosis - p. 813 259. Chapter 224: Systemic B-Cell Lymphomas Involving Skin - p. 817 260. Chapter 225: Intravascular Large B-Cell Lymphoma - p. 825 261. T-Cell and NK-Cell Neoplasms - p. 829 262. Chapter 226: Mycosis Fungoides (and Subtypes) - p. 829 263. Chapter 227: Adult T-Cell Leukemia/Lymphoma - p. 841 264. Chapter 228: Subcutaneous Panniculitis-Like T-Cell Lymphoma - p. 845 265. Chapter 229: Extranodal NK-/T-Cell Lymphoma - p. 851 266. Chapter 230: Lymphomatoid Papulosis - p. 857 267. Chapter 231: Primary Cutaneous Anaplastic Large Cell Lymphoma - p. 863 268. Chapter 232: Aggressive Epidermotropic CD8 (+) Cytotoxic T-Cell Lymphoma - p. 869 269. Chapter 233: Primary Cutaneous CD4 (+) Small/Medium T-Cell Lymphoproliferative Disorder - p. 873 270. Chapter 234: Cutaneous Gamma-Delta T-Cell Lymphoma - p. 879 271. Chapter 235: Nodal T-Follicular Helper Cell Lymphoma, Angioimmunoblastic Type - p. 885 272. Chapter 236: Systemic T-Cell and NK-Cell Lymphomas Involving Skin - p. 891 273. Leukemic and Nonlymphoid Infiltrates - p. 897 274. Chapter 237: Leukemia Cutis - p. 897 275. Chapter 238: Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 903 276. Chapter 239: Extramedullary Hematopoiesis - p. 911 277. Chapter 240: Cutaneous and Systemic Mastocytosis - p. 913 278. Section 14: Tumors of Uncertain Lineage - p. 921 279. Chapter 241: Myoepithelioma of Soft Tissue - p. 921 280. Chapter 242: Epithelioid Sarcoma - p. 931 281. Chapter 243: Cellular Neurothekeoma - p. 937 282. Chapter 244: Pecomas - p. 941 283. Chapter 245: CIC-Rearranged Sarcoma - p. 947 284. Chapter 246: NTRK-Rearranged Spindle Cell Neoplasms - p. 953 285. Chapter 247: GLI1-Altered Mesenchymal Tumor - p. 957 286. Index - p. 959
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering a broad array of cutaneous neoplasms and their differential diagnoses, it incorporates the most recent clinical, pathological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Succinctly written, richly illustrated, and easy to use, Diagnostic Pathology: Neoplastic Dermatopathology, fourth edition, is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource.
1. Cover Image - p. Cover 2. Title Page - p. ii 3. Table of Contents - p. iii 4. Contributing Authors - p. iv 5. Copyright - p. v 6. Dedications - p. v 7. Additional Contributors - p. vii 8. Preface - p. vii 9. Acknowledgments - p. viii 10. Sections - p. xi 11. List of Tables - p. xiii 12. Part I: Melanocytic Tumors of Skin - p. 1 13. Section 1: Benign Melanocytic Tumors (Nevi) - p. 1 14. Chapter 1: Congenital Melanocytic Nevi - p. 1 15. Chapter 2: Common Acquired Melanocytic Nevi - p. 5 16. Chapter 3: Common Blue Nevi - p. 9 17. Chapter 4: Cellular Blue Nevi - p. 13 18. Chapter 5: Combined Nevi - p. 17 19. Chapter 6: Halo Nevi - p. 19 20. Chapter 7: Nevi of Special Sites - p. 21 21. Chapter 8: Deep Penetrating/Inverted Type A Nevi - p. 25 22. Chapter 9: Conjunctival Melanocytic Nevi - p. 29 23. Chapter 10: Dermal Melanocytosis: Acquired and Congenital - p. 33 24. Chapter 11: Atypical/Dysplastic Melanocytic Nevi - p. 35 25. Chapter 12: Spitz (Spindle and Epithelioid Cell) Nevi - p. 39 26. Chapter 13: Pigmented Spindle Cell Nevi (Reed Nevi) - p. 45 27. Chapter 14: BAP1-Inactivated Melanocytoma - p. 49 28. Section 2: Malignant Tumors (Melanomas and Related Lesions) - p. 53 29. Melanoma In Situ - p. 53 30. Chapter 15: Melanoma In Situ, Lentigo Maligna Type - p. 53 31. Chapter 16: Melanoma In Situ, Superficial Spreading Type - p. 59 32. Chapter 17: Melanoma In Situ, Not Otherwise Specified - p. 63 33. Invasive Melanoma - p. 67 34. Chapter 18: Melanoma in Childhood - p. 67 35. Chapter 19: Atypical/Borderline and Malignant Spitz Tumors - p. 71 36. Chapter 20: Melanoma, Lentigo Maligna Type - p. 77 37. Chapter 21: Melanoma, Superficial Spreading Type - p. 81 38. Chapter 22: Melanoma, Nodular Type - p. 85 39. Chapter 23: Melanoma, Desmoplastic Type - p. 89 40. Chapter 24: Melanoma, Nevoid Type - p. 95 41. Chapter 25: Melanoma, Acral Type - p. 99 42. Chapter 26: Melanoma, Oral Type - p. 103 43. Chapter 27: Melanoma, Mucosal (Genital) Type - p. 107 44. Chapter 28: Melanoma, Sinonasal Mucosal Type - p. 111 45. Chapter 29: Melanoma, Conjunctival Type - p. 117 46. Chapter 30: Malignant Cellular Blue Nevus (Melanoma Arising in or Mimicking Cellular Blue Nevus) - p. 121 47. Chapter 31: Pigmented Epithelioid Melanocytoma - p. 125 48. Chapter 32: Melanoma, Primary Dermal Type - p. 129 49. Chapter 33: Melanoma, Other Unusual and Rare Variants - p. 131 50. Chapter 34: Staging for Specimens of Malignant Melanoma of Skin - p. 135 51. Part II: Nonmelanocytic Tumors of Skin - p. 139 52. Section 1: Epithelial Cysts - p. 139 53. Chapter 35: Epidermoid/Epidermal Inclusion Cyst - p. 139 54. Chapter 36: Pilar (Trichilemmal) Cyst - p. 143 55. Chapter 37: Proliferating Pilar (Trichilemmal) Cyst/Tumor - p. 145 56. Chapter 38: HPV-Related Epidermal Cyst - p. 149 57. Chapter 39: Vellus Hair Cyst - p. 151 58. Chapter 40: Steatocystoma (Multiplex) - p. 153 59. Chapter 41: Cutaneous Keratocyst - p. 155 60. Chapter 42: Milium - p. 157 61. Chapter 43: Hidrocystoma (Apocrine and Eccrine) - p. 159 62. Chapter 44: Digital Mucous Cyst - p. 161 63. Chapter 45: Bronchogenic Cyst - p. 163 64. Chapter 46: Branchial Cleft Cyst - p. 165 65. Chapter 47: Median Raphe Cyst - p. 171 66. Chapter 48: Cutaneous Ciliated Cyst - p. 173 67. Section 2: Epidermal Tumors - p. 175 68. Benign Epidermal Tumors and Proliferative Lesions - p. 175 69. Chapter 49: Epidermal Nevus - p. 175 70. Chapter 50: Seborrheic Keratosis (and Variants) - p. 181 71. Chapter 51: Pseudoepitheliomatous Hyperplasia - p. 187 72. Chapter 52: Warty Dyskeratoma - p. 189 73. Chapter 53: Acantholytic and Acantholytic Dyskeratotic Acanthoma - p. 193 74. Chapter 54: Verruca Vulgaris (and Variants) - p. 195 75. Chapter 55: Condyloma Acuminatum (Genital Wart) - p. 199 76. Chapter 56: Prurigo Nodularis - p. 203 77. Chapter 57: Large Cell Acanthoma - p. 205 78. Chapter 58: Clear Cell Acanthoma - p. 207 79. Chapter 59: Clear Cell Papulosis - p. 209 80. Chapter 60: Toker Cell Hyperplasia - p. 211 81. Chapter 61: Porokeratosis - p. 213 82. Premalignant and Malignant Epidermal Tumors - p. 217 83. Chapter 62: Actinic Keratosis - p. 217 84. Chapter 63: Actinic Cheilitis - p. 221 85. Chapter 64: Squamous Cell Carcinoma In Situ (Bowen Disease) - p. 223 86. Chapter 65: Bowenoid Papulosis - p. 227 87. Chapter 66: Penile and Vulvar Intraepithelial Neoplasia - p. 229 88. Chapter 67: Epidermodysplasia Verruciformis - p. 233 89. Chapter 68: Verrucous Carcinoma (and Variants) - p. 235 90. Chapter 69: Squamous Cell Carcinoma (and Variants) - p. 241 91. Chapter 70: Keratoacanthoma - p. 247 92. Chapter 71: Lymphoepithelioma-Like Carcinoma of Skin - p. 251 93. Chapter 72: Basal Cell Carcinoma - p. 253 94. Chapter 73: Extramammary Paget Disease - p. 259 95. Chapter 74: Squamomelanocytic Tumor - p. 263 96. Chapter 75: Staging for Specimens of Squamous Cell Carcinoma of Skin - p. 265 97. Section 3: Tumors and Tumor-Like Conditions of Hair Follicle - p. 267 98. Chapter 76: Nevus Sebaceus and Follicular Hamartomas - p. 267 99. Chapter 77: Trichofolliculoma - p. 273 100. Chapter 78: Trichoadenoma - p. 275 101. Chapter 79: Trichoepithelioma - p. 277 102. Chapter 80: Trichoblastoma and Trichoblastic Carcinoma - p. 281 103. Chapter 81: Panfolliculoma - p. 285 104. Chapter 82: Tumor of Follicular Infundibulum - p. 287 105. Chapter 83: Dilated Pore of Winer - p. 289 106. Chapter 84: Pilar Sheath Acanthoma - p. 291 107. Chapter 85: Inverted Follicular Keratosis - p. 293 108. Chapter 86: Trichilemmoma - p. 295 109. Chapter 87: Trichilemmal Carcinoma - p. 299 110. Chapter 88: Pilomatrixoma and Pilomatrical Carcinoma - p. 301 111. Chapter 89: Fibrofolliculoma and Trichodiscoma - p. 305 112. Section 4: Tumors and Tumor-Like Conditions with Sebaceous Differentiation - p. 307 113. Chapter 90: Sebaceous Hyperplasia - p. 307 114. Chapter 91: Superficial Epithelioma with Sebaceous Differentiation - p. 311 115. Chapter 92: Sebaceoma (Sebaceous Epithelioma) - p. 313 116. Chapter 93: Sebaceous Adenoma - p. 317 117. Chapter 94: Sebaceous Carcinoma - p. 319 118. Section 5: Neoplasms and Proliferations of Eccrine and Apocrine Sweat Glands - p. 325 119. Chapter 95: Tubular Apocrine Adenoma - p. 325 120. Chapter 96: Syringocystadenoma Papilliferum - p. 329 121. Chapter 97: Hidradenoma Papilliferum - p. 333 122. Chapter 98: Hidradenoma - p. 335 123. Chapter 99: Hidradenocarcinoma - p. 339 124. Chapter 100: Poroma and Dermal Duct Tumor - p. 343 125. Chapter 101: Porocarcinoma - p. 347 126. Chapter 102: Cylindroma and Cylindrocarcinoma - p. 349 127. Chapter 103: Spiradenoma and Spiradenocarcinoma - p. 355 128. Chapter 104: Adenoid Cystic Carcinoma - p. 359 129. Chapter 105: Primary Cutaneous Endocrine Mucin-Producing Carcinoma - p. 361 130. Chapter 106: Primary Cutaneous Mucinous Carcinoma - p. 363 131. Chapter 107: Apocrine Carcinoma (Apocrine Adenocarcinoma) - p. 367 132. Chapter 108: Digital Papillary Adenocarcinoma - p. 369 133. Chapter 109: Eccrine Hamartomas - p. 373 134. Chapter 110: Papillary Eccrine Adenoma - p. 375 135. Chapter 111: Syringoma - p. 377 136. Chapter 112: Syringofibroadenoma - p. 379 137. Chapter 113: Eccrine Carcinoma - p. 381 138. Chapter 114: Squamoid Eccrine Ductal Carcinoma - p. 383 139. Chapter 115: Microcystic Adnexal Carcinoma - p. 385 140. Chapter 116: Cutaneous Mixed Tumor (Chondroid Syringoma) - p. 389 141. Chapter 117: Malignant Mixed Tumor - p. 393 142. Section 6: Nail Tumors - p. 395 143. Chapter 118: Onychomatricoma - p. 395 144. Chapter 119: Onychopapilloma - p. 399 145. Chapter 120: Onychocytic Matricoma - p. 401 146. Section 7: Metastatic Tumors - p. 403 147. Chapter 121: Metastatic Skin Tumors - p. 403 148. Chapter 122: Metastatic Tumors to Skin - p. 409 149. Section 8: Fibrous and “Fibrohistiocytic” Tissue Tumors - p. 415 150. Benign Fibrous and “Fibrohistiocytic” Tissue Tumors - p. 415 151. Chapter 123: Fibroepithelial Polyp (Acrochordon) - p. 415 152. Chapter 124: Keloids and Hypertrophic Scars - p. 419 153. Chapter 125: Desmoplastic Fibroblastoma - p. 421 154. Chapter 126: Pleomorphic Fibroma - p. 423 155. Chapter 127: Sclerotic Fibroma - p. 425 156. Chapter 128: Fibromatosis - p. 427 157. Chapter 129: Juvenile Hyaline Fibromatosis - p. 433 158. Chapter 130: Angiofibroma and Related Lesions - p. 435 159. Chapter 131: Acral Fibrokeratoma - p. 437 160. Chapter 132: Dermatofibroma and Fibrous Histiocytoma - p. 439 161. Chapter 133: Epithelioid Cell Histiocytoma - p. 445 162. Chapter 134: Dermatomyofibroma - p. 447 163. Chapter 135: Fibrous Hamartoma of Infancy - p. 449 164. Chapter 136: Inclusion Body Fibromatosis - p. 455 165. Chapter 137: Angiomyofibroblastoma - p. 459 166. Chapter 138: Multinucleate Cell Angiohistiocytoma - p. 463 167. Chapter 139: Localized-Type Tenosynovial Giant Cell Tumor - p. 465 168. Chapter 140: Myofibroma and Myofibromatosis - p. 471 169. Chapter 141: Cutaneous Myxoma and Angiomyxoma - p. 475 170. Chapter 142: Acral Fibromyxoma - p. 477 171. Chapter 143: Pseudosarcomatous Fibroblastic Proliferations - p. 481 172. Atypical and Malignant Fibrous and “Fibrohistiocytic” Tissue Tumors - p. 489 173. Chapter 144: Angiomatoid Fibrous Histiocytoma - p. 489 174. Chapter 145: Plexiform Fibrohistiocytic Tumor - p. 497 175. Chapter 146: Dermatofibrosarcoma Protuberans - p. 501 176. Chapter 147: Atypical Fibroxanthoma - p. 507 177. Chapter 148: Pleomorphic (Dermal) Sarcoma - p. 513 178. Chapter 149: Adult-Type Fibrosarcoma - p. 515 179. Chapter 150: Myxofibrosarcoma - p. 517 180. Chapter 151: Superficial Low-Grade Fibromyxoid Sarcoma - p. 521 181. Chapter 152: Myxoinflammatory Fibroblastic Sarcoma - p. 523 182. Chapter 153: Superficial CD34 (+) Fibroblastic Tumor - p. 531 183. Chapter 154: EWSR1::SMAD3 Fibroblastic Tumor - p. 535 184. Section 9: Vascular and Perivascular Tumors and Pseudotumors - p. 539 185. Chapter 155: Vascular Malformations - p. 539 186. Chapter 156: Arteriovenous Tumor - p. 545 187. Chapter 157: Capillary Hemangioma - p. 547 188. Chapter 158: Venous Malformations - p. 549 189. Chapter 159: Infantile and Congenital Hemangiomas - p. 553 190. Chapter 160: Sinusoidal Hemangioma - p. 557 191. Chapter 161: Tufted Angioma - p. 559 192. Chapter 162: Glomeruloid Hemangioma - p. 561 193. Chapter 163: Angiolymphoid Hyperplasia with Eosinophilia - p. 563 194. Chapter 164: Hobnail (Targetoid Hemosiderotic) Hemangioma - p. 565 195. Chapter 165: Spindle Cell Hemangioma - p. 567 196. Chapter 166: Microvenular Hemangioma - p. 569 197. Chapter 167: Verrucous Venous Malformation - p. 571 198. Chapter 168: Angiokeratoma - p. 573 199. Chapter 169: Venous Lake - p. 575 200. Chapter 170: Papillary Endothelial Hyperplasia (Masson Tumor) - p. 577 201. Chapter 171: Glomus Tumors - p. 579 202. Chapter 172: Lymphatic Malformation - p. 585 203. Chapter 173: Progressive Lymphangioma - p. 589 204. Chapter 174: Bacillary Angiomatosis - p. 591 205. Chapter 175: Kaposi Sarcoma - p. 593 206. Chapter 176: Kaposiform Hemangioendothelioma - p. 601 207. Chapter 177: Epithelioid Hemangioendothelioma - p. 603 208. Chapter 178: Retiform Hemangioendothelioma - p. 609 209. Chapter 179: Papillary Intralymphatic Angioendothelioma - p. 611 210. Chapter 180: Atypical Vascular Lesion - p. 613 211. Chapter 181: Angiosarcoma - p. 615 212. Section 10: Tumors and Tumor-Like Conditions with Neural, Nerve Sheath, and Neuroendocrine Differentiation - p. 621 213. Chapter 182: Neuromas - p. 621 214. Chapter 183: Neurofibroma - p. 627 215. Chapter 184: Schwannoma - p. 637 216. Chapter 185: Dermal Nerve Sheath Myxoma - p. 651 217. Chapter 186: Granular Cell Tumor - p. 655 218. Chapter 187: Lipomatosis of Nerve - p. 661 219. Chapter 188: Perineurioma - p. 663 220. Chapter 189: Nasal Glial Heterotopia - p. 667 221. Chapter 190: Ectopic Meningioma and Meningothelial Hamartoma - p. 669 222. Chapter 191: Superficial Malignant Peripheral Nerve Sheath Tumor - p. 671 223. Chapter 192: Superficial Ewing Sarcoma - p. 675 224. Chapter 193: Primary Neuroendocrine (Merkel Cell) Carcinoma - p. 679 225. Section 11: Tumors of Muscle, Fat, Cartilage, and Bone - p. 683 226. Chapter 194: Congenital Smooth Muscle Hamartoma - p. 683 227. Chapter 195: Leiomyoma (Pilar) - p. 687 228. Chapter 196: Angioleiomyoma - p. 691 229. Chapter 197: Leiomyosarcoma - p. 693 230. Chapter 198: Rhabdomyoma - p. 697 231. Chapter 199: Cutaneous Rhabdomyosarcoma - p. 701 232. Chapter 200: Lipoma - p. 705 233. Chapter 201: Angiolipoma - p. 711 234. Chapter 202: Spindle Cell/Pleomorphic Lipoma - p. 715 235. Chapter 203: Chondroid Lipoma - p. 721 236. Chapter 204: Nevus Lipomatosus - p. 725 237. Chapter 205: Hibernoma - p. 727 238. Chapter 206: Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma - p. 731 239. Chapter 207: Soft Tissue Chondroma - p. 737 240. Chapter 208: Osteoma Cutis - p. 743 241. Section 12: Histiocytic Proliferations - p. 745 242. Chapter 209: Juvenile and Adult-Type Xanthogranuloma - p. 745 243. Chapter 210: Reticulohistiocytoma - p. 751 244. Chapter 211: Multicentric Reticulohistiocytosis - p. 755 245. Chapter 212: Langerhans Cell Histiocytosis - p. 757 246. Chapter 213: Non-Langerhans Cell Histiocytoses - p. 761 247. Chapter 214: Rosai-Dorfman Disease - p. 769 248. Chapter 215: Histiocytic Sarcoma - p. 775 249. Chapter 216: Polyvinylpyrrolidone Storage Disease - p. 779 250. Chapter 217: Xanthomas - p. 781 251. Chapter 218: Verruciform Xanthoma - p. 785 252. Section 13: Lymphomas and Hematopoietic Proliferations - p. 787 253. B-Cell Neoplasms - p. 787 254. Chapter 219: Cutaneous Plasmacytoma - p. 787 255. Chapter 220: Primary Cutaneous Marginal Zone Lymphoma - p. 793 256. Chapter 221: Primary Cutaneous Follicle Center Lymphoma - p. 799 257. Chapter 222: Diffuse Large B-Cell Lymphoma, Leg Type - p. 805 258. Chapter 223: Lymphomatoid Granulomatosis - p. 813 259. Chapter 224: Systemic B-Cell Lymphomas Involving Skin - p. 817 260. Chapter 225: Intravascular Large B-Cell Lymphoma - p. 825 261. T-Cell and NK-Cell Neoplasms - p. 829 262. Chapter 226: Mycosis Fungoides (and Subtypes) - p. 829 263. Chapter 227: Adult T-Cell Leukemia/Lymphoma - p. 841 264. Chapter 228: Subcutaneous Panniculitis-Like T-Cell Lymphoma - p. 845 265. Chapter 229: Extranodal NK-/T-Cell Lymphoma - p. 851 266. Chapter 230: Lymphomatoid Papulosis - p. 857 267. Chapter 231: Primary Cutaneous Anaplastic Large Cell Lymphoma - p. 863 268. Chapter 232: Aggressive Epidermotropic CD8 (+) Cytotoxic T-Cell Lymphoma - p. 869 269. Chapter 233: Primary Cutaneous CD4 (+) Small/Medium T-Cell Lymphoproliferative Disorder - p. 873 270. Chapter 234: Cutaneous Gamma-Delta T-Cell Lymphoma - p. 879 271. Chapter 235: Nodal T-Follicular Helper Cell Lymphoma, Angioimmunoblastic Type - p. 885 272. Chapter 236: Systemic T-Cell and NK-Cell Lymphomas Involving Skin - p. 891 273. Leukemic and Nonlymphoid Infiltrates - p. 897 274. Chapter 237: Leukemia Cutis - p. 897 275. Chapter 238: Blastic Plasmacytoid Dendritic Cell Neoplasm - p. 903 276. Chapter 239: Extramedullary Hematopoiesis - p. 911 277. Chapter 240: Cutaneous and Systemic Mastocytosis - p. 913 278. Section 14: Tumors of Uncertain Lineage - p. 921 279. Chapter 241: Myoepithelioma of Soft Tissue - p. 921 280. Chapter 242: Epithelioid Sarcoma - p. 931 281. Chapter 243: Cellular Neurothekeoma - p. 937 282. Chapter 244: Pecomas - p. 941 283. Chapter 245: CIC-Rearranged Sarcoma - p. 947 284. Chapter 246: NTRK-Rearranged Spindle Cell Neoplasms - p. 953 285. Chapter 247: GLI1-Altered Mesenchymal Tumor - p. 957 286. Index - p. 959
