Covering all aspects of soft tissue pathology, this highly regarded volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training—both as a quick reference and as an efficient review to improve knowledge and skills. Specifically designed as a point-of-care resource, the updated third edition uses a templated, highly formatted design; concise, bulleted text; and superior color images throughout that demonstrate the variety of differentiating factors in soft tissue tumors.
1. SECTION 1: SOFT TISSUE INTRODUCTION - p. xiii 2. INTRODUCTION AND OVERVIEW - p. xiii 3. Chapter 1: Gross Examination - p. xiii 4. Chapter 2: Grading and Staging - p. 5 5. ANCILLARY TECHNIQUES - p. 11 6. Chapter 3: Soft Tissue Immunohistochemistry - p. 11 7. Chapter 4: Molecular Features of Soft Tissue Tumors - p. 17 8. SECTION 2: DIAGNOSTIC APPROACH TO SOFT TISSUE TUMORS - p. 19 9. OVERVIEW - p. 19 10. Chapter 5: Biopsy and Resection of Soft Tissue Tumors - p. 19 11. CLINICAL APPROACH - p. 25 12. Chapter 6: Age- and Location-Based Approach to Diagnosis - p. 25 13. HISTOLOGIC APPROACH - p. 27 14. Chapter 7: Pattern-Based Approach to Diagnosis - p. 27 15. Chapter 8: Feature-Based Approach to Diagnosis - p. 35 16. SECTION 3: TUMORS OF ADIPOSE TISSUE - p. 43 17. BENIGN - p. 43 18. Chapter 9: Lipoma - p. 43 19. Chapter 10: Lipomatosis of Nerve - p. 51 20. Chapter 11: Synovial Lipomatosis - p. 53 21. Chapter 12: Angiolipoma - p. 55 22. Chapter 13: Spindle Cell/Pleomorphic Lipoma - p. 59 23. Chapter 14: Chondroid Lipoma - p. 65 24. Chapter 15: Myolipoma - p. 69 25. Chapter 16: Hibernoma - p. 73 26. Chapter 17: Myelolipoma - p. 77 27. Chapter 18: Lipoblastoma - p. 79 28. Chapter 19: Atypical Spindle Cell Lipomatous Tumor - p. 83 29. INTERMEDIATE, LOCALLY AGGRESSIVE - p. 87 30. Chapter 20: Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma - p. 87 31. MALIGNANT - p. 93 32. Chapter 21: Dedifferentiated Liposarcoma - p. 93 33. Chapter 22: Myxoid Liposarcoma - p. 99 34. Chapter 23: Pleomorphic Liposarcoma - p. 105 35. SECTION 4: FIBROBLASTIC/MYOFIBROBLASTIC LESIONS - p. 111 36. BENIGN - p. 111 37. Chapter 24: Nodular Fasciitis - p. 111 38. Chapter 25: Proliferative Fasciitis/Myositis - p. 119 39. Chapter 26: Ischemic Fasciitis - p. 123 40. Chapter 27: Myositis Ossificans - p. 125 41. Chapter 28: Fibroosseous Pseudotumor of Digit - p. 129 42. Chapter 29: Fibroma of Tendon Sheath - p. 133 43. Chapter 30: Desmoplastic Fibroblastoma - p. 139 44. Chapter 31: Elastofibroma - p. 141 45. Chapter 32: Angiofibroma of Soft Tissue - p. 143 46. Chapter 33: Mammary-Type Myofibroblastoma - p. 147 47. Chapter 34: Intranodal Palisaded Myofibroblastoma - p. 151 48. Chapter 35: Pleomorphic Fibroma - p. 155 49. Chapter 36: Dermatomyofibroma - p. 157 50. Chapter 37: Storiform Collagenoma - p. 159 51. Chapter 38: Keloid - p. 161 52. Chapter 39: Nuchal-Type Fibroma - p. 163 53. INTERMEDIATE (LOCALLY AGGRESSIVE) - p. 165 54. Chapter 40: Palmar/Plantar Fibromatosis - p. 165 55. Chapter 41: Desmoid-Type Fibromatosis - p. 167 56. INTERMEDIATE (RARELY METASTASIZING) - p. 173 57. Chapter 42: Dermatofibrosarcoma Protuberans - p. 173 58. Chapter 43: Solitary Fibrous Tumor - p. 183 59. Chapter 44: Low-Grade Myofibroblastic Sarcoma - p. 191 60. Chapter 45: Inflammatory Myofibroblastic Tumor - p. 195 61. Chapter 46: Myxoinflammatory Fibroblastic Sarcoma - p. 201 62. Chapter 47: Superficial CD34(+) Fibroblastic Tumor - p. 209 63. MALIGNANT - p. 213 64. Chapter 48: Adult-Type Fibrosarcoma - p. 213 65. Chapter 49: Myxofibrosarcoma - p. 215 66. Chapter 50: Low-Grade Fibromyxoid Sarcoma - p. 221 67. Chapter 51: Sclerosing Epithelioid Fibrosarcoma - p. 231 68. SECTION 5: PEDIATRIC FIBROBLASTIC/MYOFIBROBLASTIC TUMORS - p. 237 69. BENIGN - p. 237 70. Chapter 52: Fibrous Hamartoma of Infancy - p. 237 71. Chapter 53: Calcifying Aponeurotic Fibroma - p. 243 72. Chapter 54: Calcifying Fibrous Tumor - p. 247 73. Chapter 55: Inclusion Body Fibromatosis - p. 249 74. Chapter 56: Hyaline Fibromatosis Syndrome - p. 251 75. Chapter 57: Fibromatosis Colli - p. 253 76. Chapter 58: Gardner Fibroma - p. 255 77. INTERMEDIATE (LOCALLY AGGRESSIVE) - p. 257 78. Chapter 59: Lipofibromatosis - p. 257 79. Chapter 60: Giant Cell Fibroblastoma - p. 259 80. INTERMEDIATE (RARELY METASTASIZING) - p. 263 81. Chapter 61: Infantile Fibrosarcoma - p. 263 82. SECTION 6: FIBROHISTIOCYTIC, HISTIOCYTIC, AND DENDRITIC CELL TUMORS - p. 267 83. BENIGN - p. 267 84. Chapter 62: Dermatofibroma and Fibrous Histiocytoma - p. 267 85. Chapter 63: Deep Benign Fibrous Histiocytoma - p. 275 86. Chapter 64: Localized-Type Tenosynovial Giant Cell Tumor - p. 277 87. Chapter 65: Diffuse-Type Tenosynovial Giant Cell Tumor - p. 283 88. Chapter 66: Cellular Neurothekeoma - p. 289 89. Chapter 67: Xanthomas - p. 293 90. Chapter 68: Solitary (Juvenile) Xanthogranuloma - p. 297 91. Chapter 69: Reticulohistiocytoma - p. 299 92. Chapter 70: Deep Granuloma Annulare - p. 303 93. Chapter 71: Rheumatoid Nodule - p. 305 94. Chapter 72: Langerhans Cell Histiocytosis - p. 307 95. Chapter 73: Extranodal Rosai-Dorfman Disease - p. 309 96. Chapter 74: Crystal-Storing Histiocytosis - p. 313 97. INTERMEDIATE (RARELY METASTASIZING) - p. 315 98. Chapter 75: Plexiform Fibrohistiocytic Tumor - p. 315 99. Chapter 76: Giant Cell Tumor of Soft Tissue - p. 319 100. MALIGNANT - p. 323 101. Chapter 77: Histiocytic Sarcoma - p. 323 102. Chapter 78: Follicular Dendritic Cell Sarcoma - p. 325 103. Chapter 79: Interdigitating Dendritic Cell Sarcoma - p. 327 104. SECTION 7: SMOOTH MUSCLE TUMORS - p. 329 105. BENIGN - p. 329 106. Chapter 80: Smooth Muscle Hamartoma - p. 329 107. Chapter 81: Superficial Leiomyoma - p. 333 108. Chapter 82: Deep Leiomyoma - p. 337 109. INTERMEDIATE - p. 341 110. Chapter 83: Epstein-Barr Virus-Associated Smooth Muscle Tumor - p. 341 111. MALIGNANT - p. 343 112. Chapter 84: Leiomyosarcoma - p. 343 113. SECTION 8: PERICYTIC (PERIVASCULAR) TUMORS - p. 349 114. BENIGN - p. 349 115. Chapter 85: Glomus Tumors (and Variants) - p. 349 116. Chapter 86: Myopericytoma - p. 357 117. Chapter 87: Myofibroma and Myofibromatosis - p. 361 118. Chapter 88: Angioleiomyoma - p. 365 119. SECTION 9: TUMORS OF SKELETAL MUSCLE - p. 367 120. BENIGN - p. 367 121. Chapter 89: Focal Myositis - p. 367 122. Chapter 90: Adult Rhabdomyoma - p. 371 123. Chapter 91: Fetal Rhabdomyoma - p. 373 124. Chapter 92: Genital Rhabdomyoma - p. 375 125. Chapter 93: Cardiac Rhabdomyoma - p. 377 126. MALIGNANT - p. 379 127. Chapter 94: Embryonal Rhabdomyosarcoma - p. 379 128. Chapter 95: Alveolar Rhabdomyosarcoma - p. 385 129. Chapter 96: Spindle Cell Rhabdomyosarcoma - p. 391 130. Chapter 97: Sclerosing Rhabdomyosarcoma - p. 395 131. Chapter 98: Pleomorphic Rhabdomyosarcoma - p. 399 132. Chapter 99: Epithelioid Rhabdomyosarcoma - p. 403 133. SECTION 10: VASCULAR TUMORS (INCLUDING LYMPHATICS) - p. 405 134. BENIGN - p. 405 135. Chapter 100: Papillary Endothelial Hyperplasia - p. 405 136. Chapter 101: Bacillary Angiomatosis - p. 409 137. Chapter 102: Congenital Hemangioma - p. 411 138. Chapter 103: Infantile Hemangioma - p. 415 139. Chapter 104: Lobular Capillary Hemangioma - p. 419 140. Chapter 105: Epithelioid Hemangioma - p. 421 141. Chapter 106: Spindle Cell Hemangioma - p. 425 142. Chapter 107: Intramuscular Hemangioma - p. 429 143. Chapter 108: Hobnail Hemangioma - p. 433 144. Chapter 109: Acquired Tufted Angioma - p. 435 145. Chapter 110: Microvenular Hemangioma - p. 437 146. Chapter 111: Sinusoidal Hemangioma - p. 439 147. Chapter 112: Glomeruloid Hemangioma - p. 441 148. Chapter 113: Angiomatosis - p. 443 149. Chapter 114: Lymphangioma - p. 445 150. Chapter 115: Massive Localized Lymphedema - p. 449 151. Chapter 116: Atypical Vascular Lesion - p. 451 152. INTERMEDIATE (LOCALLY AGGRESSIVE) - p. 453 153. Chapter 117: Kaposiform Hemangioendothelioma - p. 453 154. INTERMEDIATE (RARELY METASTASIZING) - p. 455 155. Chapter 118: Papillary Intralymphatic Angioendothelioma - p. 455 156. Chapter 119: Retiform Hemangioendothelioma - p. 457 157. Chapter 120: Composite Hemangioendothelioma - p. 459 158. Chapter 121: Pseudomyogenic Hemangioendothelioma - p. 461 159. MALIGNANT - p. 465 160. Chapter 122: Epithelioid Hemangioendothelioma - p. 465 161. Chapter 123: Angiosarcoma - p. 469 162. Chapter 124: Kaposi Sarcoma - p. 475 163. SECTION 11: CHONDROOSSEOUS TUMORS - p. 483 164. BENIGN - p. 483 165. Chapter 125: Soft Tissue Chondroma - p. 483 166. Chapter 126: Synovial Chondromatosis - p. 491 167. MALIGNANT - p. 495 168. Chapter 127: Extraskeletal Osteosarcoma - p. 495 169. Chapter 128: Extraskeletal Mesenchymal Chondrosarcoma - p. 499 170. SECTION 12: PERIPHERAL NERVE SHEATH TUMORS - p. 503 171. BENIGN - p. 503 172. Chapter 129: Solitary Circumscribed Neuroma - p. 503 173. Chapter 130: Schwannoma - p. 507 174. Chapter 131: Neurofibroma - p. 521 175. Chapter 132: Perineurioma - p. 529 176. Chapter 133: Hybrid Nerve Sheath Tumor - p. 535 177. Chapter 134: Granular Cell Tumor - p. 539 178. Chapter 135: Dermal Nerve Sheath Myxoma - p. 545 179. Chapter 136: Ganglioneuroma - p. 549 180. Chapter 137: Neuromuscular Choristoma - p. 553 181. INTERMEDIATE - p. 555 182. Chapter 138: Melanotic Schwannoma - p. 555 183. MALIGNANT - p. 557 184. Chapter 139: Malignant Peripheral Nerve Sheath Tumor - p. 557 185. Chapter 140: Epithelioid Malignant Peripheral Nerve Sheath Tumor - p. 565 186. Chapter 141: Ectomesenchymoma - p. 569 187. SECTION 13: GENITAL STROMAL TUMORS - p. 571 188. Chapter 142: Fibroepithelial Stromal Polyp - p. 571 189. Chapter 143: Angiomyofibroblastoma - p. 575 190. Chapter 144: Cellular Angiofibroma - p. 579 191. Chapter 145: Deep (Aggressive) Angiomyxoma - p. 583 192. SECTION 14: TUMORS OF MESOTHELIAL CELLS - p. 587 193. BENIGN - p. 587 194. Chapter 146: Adenomatoid Tumor - p. 587 195. Chapter 147: Multicystic Peritoneal Mesothelioma - p. 591 196. Chapter 148: Well-Differentiated Papillary Mesothelioma - p. 593 197. MALIGNANT - p. 597 198. Chapter 149: Malignant Mesothelioma - p. 597 199. SECTION 15: HEMATOPOIETIC TUMORS IN SOFT TISSUE - p. 603 200. Chapter 150: Solitary Extramedullary Plasmacytoma - p. 603 201. Chapter 151: Myeloid Sarcoma - p. 607 202. Chapter 152: Lymphoma of Soft Tissue - p. 609 203. SECTION 16: TUMORS OF UNCERTAIN DIFFERENTIATION - p. 611 204. BENIGN - p. 611 205. Chapter 153: Intramuscular Myxoma - p. 611 206. Chapter 154: Juxtaarticular Myxoma - p. 617 207. Chapter 155: Superficial Angiomyxoma - p. 619 208. Chapter 156: Acral Fibromyxoma - p. 623 209. Chapter 157: Pleomorphic Hyalinizing Angiectatic Tumor - p. 625 210. Chapter 158: Aneurysmal Bone Cyst of Soft Tissue - p. 629 211. Chapter 159: Ectopic Hamartomatous Thymoma - p. 631 212. INTERMEDIATE (LOCALLY AGGRESSIVE) - p. 633 213. Chapter 160: Hemosiderotic Fibrolipomatous Tumor - p. 633 214. INTERMEDIATE (RARELY METASTASIZING) - p. 635 215. Chapter 161: Atypical Fibroxanthoma - p. 635 216. Chapter 162: Angiomatoid Fibrous Histiocytoma - p. 641 217. Chapter 163: Ossifying Fibromyxoid Tumor - p. 649 218. Chapter 164: Myoepithelioma of Soft Tissue - p. 655 219. Chapter 165: Phosphaturic Mesenchymal Tumor - p. 663 220. MALIGNANT - p. 665 221. Chapter 166: Synovial Sarcoma - p. 665 222. Chapter 167: Epithelioid Sarcoma - p. 677 223. Chapter 168: Alveolar Soft Part Sarcoma - p. 683 224. Chapter 169: Clear Cell Sarcoma - p. 687 225. Chapter 170: Perivascular Epithelioid Cell Tumor (PEComa) - p. 691 226. Chapter 171: Desmoplastic Small Round Cell Tumor - p. 699 227. Chapter 172: Extraskeletal Ewing Sarcoma - p. 705 228. Chapter 173: Extraskeletal Myxoid Chondrosarcoma - p. 711 229. Chapter 174: Extrarenal Rhabdoid Tumor - p. 715 230. Chapter 175: Intimal Sarcoma - p. 719 231. SECTION 17: UNDIFFERENTIATED/UNCLASSIFIED SARCOMAS - p. 721 232. Chapter 176: Undifferentiated Pleomorphic Sarcoma - p. 721 233. Chapter 177: Undifferentiated Round Cell Sarcoma With CIC-DUX4 Translocation - p. 727 234. Chapter 178: BCOR-CCNB3 Fusion-Positive Sarcoma - p. 733 235. SECTION 18: MESENCHYMAL TUMORS OF GASTROINTESTINAL TRACT - p. 737 236. Chapter 179: Benign Neural Gastrointestinal Polyps - p. 737 237. Chapter 180: Gastrointestinal Stromal Tumor - p. 743 238. Chapter 181: Gastrointestinal Schwannoma - p. 759 239. Chapter 182: Gastrointestinal Smooth Muscle Neoplasms - p. 761 240. Chapter 183: Inflammatory Fibroid Polyp - p. 765 241. Chapter 184: Gangliocytic Paraganglioma - p. 769 242. Chapter 185: Plexiform Fibromyxoma - p. 771 243. Chapter 186: Malignant Gastrointestinal Neuroectodermal Tumor - p. 775 244. SECTION 19: OTHER ENTITIES - p. 779 245. BENIGN - p. 779 246. Chapter 187: Amyloidoma - p. 779 247. Chapter 188: Ganglion Cyst - p. 783 248. Chapter 189: Tumoral Calcinosis - p. 785 249. Chapter 190: Idiopathic Tumefactive Fibroinflammatory Lesions - p. 787 250. Chapter 191: Cardiac Myxoma - p. 791 251. Chapter 192: Cardiac Fibroma - p. 795 252. Chapter 193: Congenital Granular Cell Epulis - p. 797 253. Chapter 194: Nasopharyngeal Angiofibroma - p. 799 254. Chapter 195: Sinonasal Glomangiopericytoma - p. 803 255. Chapter 196: Ectopic Meningioma - p. 809 256. Chapter 197: Glial Heterotopia - p. 811 257. INTERMEDIATE - p. 813 258. Chapter 198: Paraganglioma - p. 813 259. Chapter 199: Peripheral Hemangioblastoma - p. 821 260. Chapter 200: Melanotic Neuroectodermal Tumor of Infancy - p. 823 261. Chapter 201: Ependymoma of Soft Tissue - p. 825 262. MALIGNANT - p. 827 263. Chapter 202: Metastatic Tumors to Soft Tissue Sites - p. 827 264. Chapter 203: Neuroblastoma and Ganglioneuroblastoma - p. 831 265. Chapter 204: Extraaxial Soft Tissue Chordoma - p. 841 266. Chapter 205: Undifferentiated Embryonal Sarcoma of Liver - p. 843 267. Chapter 206: Primary Pulmonary Myxoid Sarcoma - p. 845 268. Chapter 207: Biphenotypic Sinonasal Sarcoma - p. 849 269. Chapter 208: Spindle Epithelial Tumor With Thymus-Like Differentiation - p. 853 270. Chapter 209: Low-Grade Endometrial Stromal Sarcoma - p. 855 271. INDEX - p. 857
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Covering all aspects of soft tissue pathology, this highly regarded volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training—both as a quick reference and as an efficient review to improve knowledge and skills. Specifically designed as a point-of-care resource, the updated third edition uses a templated, highly formatted design; concise, bulleted text; and superior color images throughout that demonstrate the variety of differentiating factors in soft tissue tumors.
1. SECTION 1: SOFT TISSUE INTRODUCTION - p. xiii 2. INTRODUCTION AND OVERVIEW - p. xiii 3. Chapter 1: Gross Examination - p. xiii 4. Chapter 2: Grading and Staging - p. 5 5. ANCILLARY TECHNIQUES - p. 11 6. Chapter 3: Soft Tissue Immunohistochemistry - p. 11 7. Chapter 4: Molecular Features of Soft Tissue Tumors - p. 17 8. SECTION 2: DIAGNOSTIC APPROACH TO SOFT TISSUE TUMORS - p. 19 9. OVERVIEW - p. 19 10. Chapter 5: Biopsy and Resection of Soft Tissue Tumors - p. 19 11. CLINICAL APPROACH - p. 25 12. Chapter 6: Age- and Location-Based Approach to Diagnosis - p. 25 13. HISTOLOGIC APPROACH - p. 27 14. Chapter 7: Pattern-Based Approach to Diagnosis - p. 27 15. Chapter 8: Feature-Based Approach to Diagnosis - p. 35 16. SECTION 3: TUMORS OF ADIPOSE TISSUE - p. 43 17. BENIGN - p. 43 18. Chapter 9: Lipoma - p. 43 19. Chapter 10: Lipomatosis of Nerve - p. 51 20. Chapter 11: Synovial Lipomatosis - p. 53 21. Chapter 12: Angiolipoma - p. 55 22. Chapter 13: Spindle Cell/Pleomorphic Lipoma - p. 59 23. Chapter 14: Chondroid Lipoma - p. 65 24. Chapter 15: Myolipoma - p. 69 25. Chapter 16: Hibernoma - p. 73 26. Chapter 17: Myelolipoma - p. 77 27. Chapter 18: Lipoblastoma - p. 79 28. Chapter 19: Atypical Spindle Cell Lipomatous Tumor - p. 83 29. INTERMEDIATE, LOCALLY AGGRESSIVE - p. 87 30. Chapter 20: Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma - p. 87 31. MALIGNANT - p. 93 32. Chapter 21: Dedifferentiated Liposarcoma - p. 93 33. Chapter 22: Myxoid Liposarcoma - p. 99 34. Chapter 23: Pleomorphic Liposarcoma - p. 105 35. SECTION 4: FIBROBLASTIC/MYOFIBROBLASTIC LESIONS - p. 111 36. BENIGN - p. 111 37. Chapter 24: Nodular Fasciitis - p. 111 38. Chapter 25: Proliferative Fasciitis/Myositis - p. 119 39. Chapter 26: Ischemic Fasciitis - p. 123 40. Chapter 27: Myositis Ossificans - p. 125 41. Chapter 28: Fibroosseous Pseudotumor of Digit - p. 129 42. Chapter 29: Fibroma of Tendon Sheath - p. 133 43. Chapter 30: Desmoplastic Fibroblastoma - p. 139 44. Chapter 31: Elastofibroma - p. 141 45. Chapter 32: Angiofibroma of Soft Tissue - p. 143 46. Chapter 33: Mammary-Type Myofibroblastoma - p. 147 47. Chapter 34: Intranodal Palisaded Myofibroblastoma - p. 151 48. Chapter 35: Pleomorphic Fibroma - p. 155 49. Chapter 36: Dermatomyofibroma - p. 157 50. Chapter 37: Storiform Collagenoma - p. 159 51. Chapter 38: Keloid - p. 161 52. Chapter 39: Nuchal-Type Fibroma - p. 163 53. INTERMEDIATE (LOCALLY AGGRESSIVE) - p. 165 54. Chapter 40: Palmar/Plantar Fibromatosis - p. 165 55. Chapter 41: Desmoid-Type Fibromatosis - p. 167 56. INTERMEDIATE (RARELY METASTASIZING) - p. 173 57. Chapter 42: Dermatofibrosarcoma Protuberans - p. 173 58. Chapter 43: Solitary Fibrous Tumor - p. 183 59. Chapter 44: Low-Grade Myofibroblastic Sarcoma - p. 191 60. Chapter 45: Inflammatory Myofibroblastic Tumor - p. 195 61. Chapter 46: Myxoinflammatory Fibroblastic Sarcoma - p. 201 62. Chapter 47: Superficial CD34(+) Fibroblastic Tumor - p. 209 63. MALIGNANT - p. 213 64. Chapter 48: Adult-Type Fibrosarcoma - p. 213 65. Chapter 49: Myxofibrosarcoma - p. 215 66. Chapter 50: Low-Grade Fibromyxoid Sarcoma - p. 221 67. Chapter 51: Sclerosing Epithelioid Fibrosarcoma - p. 231 68. SECTION 5: PEDIATRIC FIBROBLASTIC/MYOFIBROBLASTIC TUMORS - p. 237 69. BENIGN - p. 237 70. Chapter 52: Fibrous Hamartoma of Infancy - p. 237 71. Chapter 53: Calcifying Aponeurotic Fibroma - p. 243 72. Chapter 54: Calcifying Fibrous Tumor - p. 247 73. Chapter 55: Inclusion Body Fibromatosis - p. 249 74. Chapter 56: Hyaline Fibromatosis Syndrome - p. 251 75. Chapter 57: Fibromatosis Colli - p. 253 76. Chapter 58: Gardner Fibroma - p. 255 77. INTERMEDIATE (LOCALLY AGGRESSIVE) - p. 257 78. Chapter 59: Lipofibromatosis - p. 257 79. Chapter 60: Giant Cell Fibroblastoma - p. 259 80. INTERMEDIATE (RARELY METASTASIZING) - p. 263 81. Chapter 61: Infantile Fibrosarcoma - p. 263 82. SECTION 6: FIBROHISTIOCYTIC, HISTIOCYTIC, AND DENDRITIC CELL TUMORS - p. 267 83. BENIGN - p. 267 84. Chapter 62: Dermatofibroma and Fibrous Histiocytoma - p. 267 85. Chapter 63: Deep Benign Fibrous Histiocytoma - p. 275 86. Chapter 64: Localized-Type Tenosynovial Giant Cell Tumor - p. 277 87. Chapter 65: Diffuse-Type Tenosynovial Giant Cell Tumor - p. 283 88. Chapter 66: Cellular Neurothekeoma - p. 289 89. Chapter 67: Xanthomas - p. 293 90. Chapter 68: Solitary (Juvenile) Xanthogranuloma - p. 297 91. Chapter 69: Reticulohistiocytoma - p. 299 92. Chapter 70: Deep Granuloma Annulare - p. 303 93. Chapter 71: Rheumatoid Nodule - p. 305 94. Chapter 72: Langerhans Cell Histiocytosis - p. 307 95. Chapter 73: Extranodal Rosai-Dorfman Disease - p. 309 96. Chapter 74: Crystal-Storing Histiocytosis - p. 313 97. INTERMEDIATE (RARELY METASTASIZING) - p. 315 98. Chapter 75: Plexiform Fibrohistiocytic Tumor - p. 315 99. Chapter 76: Giant Cell Tumor of Soft Tissue - p. 319 100. MALIGNANT - p. 323 101. Chapter 77: Histiocytic Sarcoma - p. 323 102. Chapter 78: Follicular Dendritic Cell Sarcoma - p. 325 103. Chapter 79: Interdigitating Dendritic Cell Sarcoma - p. 327 104. SECTION 7: SMOOTH MUSCLE TUMORS - p. 329 105. BENIGN - p. 329 106. Chapter 80: Smooth Muscle Hamartoma - p. 329 107. Chapter 81: Superficial Leiomyoma - p. 333 108. Chapter 82: Deep Leiomyoma - p. 337 109. INTERMEDIATE - p. 341 110. Chapter 83: Epstein-Barr Virus-Associated Smooth Muscle Tumor - p. 341 111. MALIGNANT - p. 343 112. Chapter 84: Leiomyosarcoma - p. 343 113. SECTION 8: PERICYTIC (PERIVASCULAR) TUMORS - p. 349 114. BENIGN - p. 349 115. Chapter 85: Glomus Tumors (and Variants) - p. 349 116. Chapter 86: Myopericytoma - p. 357 117. Chapter 87: Myofibroma and Myofibromatosis - p. 361 118. Chapter 88: Angioleiomyoma - p. 365 119. SECTION 9: TUMORS OF SKELETAL MUSCLE - p. 367 120. BENIGN - p. 367 121. Chapter 89: Focal Myositis - p. 367 122. Chapter 90: Adult Rhabdomyoma - p. 371 123. Chapter 91: Fetal Rhabdomyoma - p. 373 124. Chapter 92: Genital Rhabdomyoma - p. 375 125. Chapter 93: Cardiac Rhabdomyoma - p. 377 126. MALIGNANT - p. 379 127. Chapter 94: Embryonal Rhabdomyosarcoma - p. 379 128. Chapter 95: Alveolar Rhabdomyosarcoma - p. 385 129. Chapter 96: Spindle Cell Rhabdomyosarcoma - p. 391 130. Chapter 97: Sclerosing Rhabdomyosarcoma - p. 395 131. Chapter 98: Pleomorphic Rhabdomyosarcoma - p. 399 132. Chapter 99: Epithelioid Rhabdomyosarcoma - p. 403 133. SECTION 10: VASCULAR TUMORS (INCLUDING LYMPHATICS) - p. 405 134. BENIGN - p. 405 135. Chapter 100: Papillary Endothelial Hyperplasia - p. 405 136. Chapter 101: Bacillary Angiomatosis - p. 409 137. Chapter 102: Congenital Hemangioma - p. 411 138. Chapter 103: Infantile Hemangioma - p. 415 139. Chapter 104: Lobular Capillary Hemangioma - p. 419 140. Chapter 105: Epithelioid Hemangioma - p. 421 141. Chapter 106: Spindle Cell Hemangioma - p. 425 142. Chapter 107: Intramuscular Hemangioma - p. 429 143. Chapter 108: Hobnail Hemangioma - p. 433 144. Chapter 109: Acquired Tufted Angioma - p. 435 145. Chapter 110: Microvenular Hemangioma - p. 437 146. Chapter 111: Sinusoidal Hemangioma - p. 439 147. Chapter 112: Glomeruloid Hemangioma - p. 441 148. Chapter 113: Angiomatosis - p. 443 149. Chapter 114: Lymphangioma - p. 445 150. Chapter 115: Massive Localized Lymphedema - p. 449 151. Chapter 116: Atypical Vascular Lesion - p. 451 152. INTERMEDIATE (LOCALLY AGGRESSIVE) - p. 453 153. Chapter 117: Kaposiform Hemangioendothelioma - p. 453 154. INTERMEDIATE (RARELY METASTASIZING) - p. 455 155. Chapter 118: Papillary Intralymphatic Angioendothelioma - p. 455 156. Chapter 119: Retiform Hemangioendothelioma - p. 457 157. Chapter 120: Composite Hemangioendothelioma - p. 459 158. Chapter 121: Pseudomyogenic Hemangioendothelioma - p. 461 159. MALIGNANT - p. 465 160. Chapter 122: Epithelioid Hemangioendothelioma - p. 465 161. Chapter 123: Angiosarcoma - p. 469 162. Chapter 124: Kaposi Sarcoma - p. 475 163. SECTION 11: CHONDROOSSEOUS TUMORS - p. 483 164. BENIGN - p. 483 165. Chapter 125: Soft Tissue Chondroma - p. 483 166. Chapter 126: Synovial Chondromatosis - p. 491 167. MALIGNANT - p. 495 168. Chapter 127: Extraskeletal Osteosarcoma - p. 495 169. Chapter 128: Extraskeletal Mesenchymal Chondrosarcoma - p. 499 170. SECTION 12: PERIPHERAL NERVE SHEATH TUMORS - p. 503 171. BENIGN - p. 503 172. Chapter 129: Solitary Circumscribed Neuroma - p. 503 173. Chapter 130: Schwannoma - p. 507 174. Chapter 131: Neurofibroma - p. 521 175. Chapter 132: Perineurioma - p. 529 176. Chapter 133: Hybrid Nerve Sheath Tumor - p. 535 177. Chapter 134: Granular Cell Tumor - p. 539 178. Chapter 135: Dermal Nerve Sheath Myxoma - p. 545 179. Chapter 136: Ganglioneuroma - p. 549 180. Chapter 137: Neuromuscular Choristoma - p. 553 181. INTERMEDIATE - p. 555 182. Chapter 138: Melanotic Schwannoma - p. 555 183. MALIGNANT - p. 557 184. Chapter 139: Malignant Peripheral Nerve Sheath Tumor - p. 557 185. Chapter 140: Epithelioid Malignant Peripheral Nerve Sheath Tumor - p. 565 186. Chapter 141: Ectomesenchymoma - p. 569 187. SECTION 13: GENITAL STROMAL TUMORS - p. 571 188. Chapter 142: Fibroepithelial Stromal Polyp - p. 571 189. Chapter 143: Angiomyofibroblastoma - p. 575 190. Chapter 144: Cellular Angiofibroma - p. 579 191. Chapter 145: Deep (Aggressive) Angiomyxoma - p. 583 192. SECTION 14: TUMORS OF MESOTHELIAL CELLS - p. 587 193. BENIGN - p. 587 194. Chapter 146: Adenomatoid Tumor - p. 587 195. Chapter 147: Multicystic Peritoneal Mesothelioma - p. 591 196. Chapter 148: Well-Differentiated Papillary Mesothelioma - p. 593 197. MALIGNANT - p. 597 198. Chapter 149: Malignant Mesothelioma - p. 597 199. SECTION 15: HEMATOPOIETIC TUMORS IN SOFT TISSUE - p. 603 200. Chapter 150: Solitary Extramedullary Plasmacytoma - p. 603 201. Chapter 151: Myeloid Sarcoma - p. 607 202. Chapter 152: Lymphoma of Soft Tissue - p. 609 203. SECTION 16: TUMORS OF UNCERTAIN DIFFERENTIATION - p. 611 204. BENIGN - p. 611 205. Chapter 153: Intramuscular Myxoma - p. 611 206. Chapter 154: Juxtaarticular Myxoma - p. 617 207. Chapter 155: Superficial Angiomyxoma - p. 619 208. Chapter 156: Acral Fibromyxoma - p. 623 209. Chapter 157: Pleomorphic Hyalinizing Angiectatic Tumor - p. 625 210. Chapter 158: Aneurysmal Bone Cyst of Soft Tissue - p. 629 211. Chapter 159: Ectopic Hamartomatous Thymoma - p. 631 212. INTERMEDIATE (LOCALLY AGGRESSIVE) - p. 633 213. Chapter 160: Hemosiderotic Fibrolipomatous Tumor - p. 633 214. INTERMEDIATE (RARELY METASTASIZING) - p. 635 215. Chapter 161: Atypical Fibroxanthoma - p. 635 216. Chapter 162: Angiomatoid Fibrous Histiocytoma - p. 641 217. Chapter 163: Ossifying Fibromyxoid Tumor - p. 649 218. Chapter 164: Myoepithelioma of Soft Tissue - p. 655 219. Chapter 165: Phosphaturic Mesenchymal Tumor - p. 663 220. MALIGNANT - p. 665 221. Chapter 166: Synovial Sarcoma - p. 665 222. Chapter 167: Epithelioid Sarcoma - p. 677 223. Chapter 168: Alveolar Soft Part Sarcoma - p. 683 224. Chapter 169: Clear Cell Sarcoma - p. 687 225. Chapter 170: Perivascular Epithelioid Cell Tumor (PEComa) - p. 691 226. Chapter 171: Desmoplastic Small Round Cell Tumor - p. 699 227. Chapter 172: Extraskeletal Ewing Sarcoma - p. 705 228. Chapter 173: Extraskeletal Myxoid Chondrosarcoma - p. 711 229. Chapter 174: Extrarenal Rhabdoid Tumor - p. 715 230. Chapter 175: Intimal Sarcoma - p. 719 231. SECTION 17: UNDIFFERENTIATED/UNCLASSIFIED SARCOMAS - p. 721 232. Chapter 176: Undifferentiated Pleomorphic Sarcoma - p. 721 233. Chapter 177: Undifferentiated Round Cell Sarcoma With CIC-DUX4 Translocation - p. 727 234. Chapter 178: BCOR-CCNB3 Fusion-Positive Sarcoma - p. 733 235. SECTION 18: MESENCHYMAL TUMORS OF GASTROINTESTINAL TRACT - p. 737 236. Chapter 179: Benign Neural Gastrointestinal Polyps - p. 737 237. Chapter 180: Gastrointestinal Stromal Tumor - p. 743 238. Chapter 181: Gastrointestinal Schwannoma - p. 759 239. Chapter 182: Gastrointestinal Smooth Muscle Neoplasms - p. 761 240. Chapter 183: Inflammatory Fibroid Polyp - p. 765 241. Chapter 184: Gangliocytic Paraganglioma - p. 769 242. Chapter 185: Plexiform Fibromyxoma - p. 771 243. Chapter 186: Malignant Gastrointestinal Neuroectodermal Tumor - p. 775 244. SECTION 19: OTHER ENTITIES - p. 779 245. BENIGN - p. 779 246. Chapter 187: Amyloidoma - p. 779 247. Chapter 188: Ganglion Cyst - p. 783 248. Chapter 189: Tumoral Calcinosis - p. 785 249. Chapter 190: Idiopathic Tumefactive Fibroinflammatory Lesions - p. 787 250. Chapter 191: Cardiac Myxoma - p. 791 251. Chapter 192: Cardiac Fibroma - p. 795 252. Chapter 193: Congenital Granular Cell Epulis - p. 797 253. Chapter 194: Nasopharyngeal Angiofibroma - p. 799 254. Chapter 195: Sinonasal Glomangiopericytoma - p. 803 255. Chapter 196: Ectopic Meningioma - p. 809 256. Chapter 197: Glial Heterotopia - p. 811 257. INTERMEDIATE - p. 813 258. Chapter 198: Paraganglioma - p. 813 259. Chapter 199: Peripheral Hemangioblastoma - p. 821 260. Chapter 200: Melanotic Neuroectodermal Tumor of Infancy - p. 823 261. Chapter 201: Ependymoma of Soft Tissue - p. 825 262. MALIGNANT - p. 827 263. Chapter 202: Metastatic Tumors to Soft Tissue Sites - p. 827 264. Chapter 203: Neuroblastoma and Ganglioneuroblastoma - p. 831 265. Chapter 204: Extraaxial Soft Tissue Chordoma - p. 841 266. Chapter 205: Undifferentiated Embryonal Sarcoma of Liver - p. 843 267. Chapter 206: Primary Pulmonary Myxoid Sarcoma - p. 845 268. Chapter 207: Biphenotypic Sinonasal Sarcoma - p. 849 269. Chapter 208: Spindle Epithelial Tumor With Thymus-Like Differentiation - p. 853 270. Chapter 209: Low-Grade Endometrial Stromal Sarcoma - p. 855 271. INDEX - p. 857
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