Differentiating Factors in Alzheimer’s Disease: Gender, Ethnicity, Clinical and Treatment addresses the question why women differ from men in terms of their risk factors and how Alzheimer's disease can be prevented at the molecular level. This book reviews the epidemiology of Alzheimer's disease describing the differences in men's and women's brain anatomy and biochemistry that may account for why women are more likely to develop Alzheimer's disease. The authors offer actions that could help to prevent or slow the progression of Alzheimer's disease in addition to discussing the most recent pharmacological treatments.
1. Introduction - p. xv 2. Chapter One. Alzheimer's disease: Epidemiological and genetical approaches - p. 1 3. Chapter Two. Sex and gender differences in Alzheimer's disease - p. 15 4. Chapter Three. Alzheimer's anatomical and pathophysiological approaches - p. 25 5. Chapter Four. How and why your gender impacts your risk for dementia? - p. 37 6. Chapter Five. How and why your race impacts your risk of dementia? - p. 53 7. Chapter Six. Alzheimer's disease: Pharmacological approaches - p. 73 8. Chapter Seven. Alzheimer's disease: Interventions and preventive approaches - p. 91 9. Chapter Eight. Alzheimer's disease: Interventions, preventive, and treatment/alternative medicine and nutritional approaches - p. 113 10. Chapter Nine. Alcohol and Alzheimer's—Is there a link? - p. 129 11. Chapter Ten. Clinical investigation cases studies and critical thinking problem approaches - p. 175 12. Introduction - p. 175 13. Case 1 Diagnostic application of early-onset Alzheimer's disease (AD)∗ - p. 176 14. Objectives - p. 176 15. Case - p. 176 16. Case 2 Magnetic resonance imaging of early-onset alzheimer disease (EOAD) for AD patients with a Novel Presenilin 2 mutation∗ - p. 180 17. Case report - p. 181 18. Case 3 A precision medicine approach to multifactorial dementia and Alzheimer's disease (AD)∗ - p. 187 19. Introduction - p. 188 20. Case presentation (Ross et al., 2021) - p. 189 21. Concluding remarks - p. 202 22. Case 4 Alzheimer's dementia∗ - p. 204 23. Case report - p. 205 24. Questions - p. 206 25. Answers to the questions - p. 206 26. Clinical approach - p. 206 27. Answers - p. 208 28. Case 5 Rare genetic resilience of autosomal-dominant Alzheimer's disease PSEN1- E280A mutation in mid-age male Alzheimer's disease (AD) patient versus female AD patient∗ - p. 208 29. Case study - p. 208 30. Case report - p. 209 31. Analysis of key findings of the article - p. 211 32. Concluding remarks - p. 215 33. Case 6 Early diagnosis of AD is a must for effective treatment protocol∗ - p. 218 34. Case study - p. 218 35. Case report - p. 219 36. Case analysis for key findings - p. 220 37. Concluding remarks - p. 222 38. Case 7 Biomarkers: Biology-based criteria for the diagnosis of Alzheimer's disease∗ - p. 224 39. Objectives - p. 224 40. Key highlights - p. 224 41. Key principles - p. 225 42. Alzheimer's biomarkers categorization - p. 226 43. Concluding remarks - p. 232 44. Case 8 Alzheimer's genetic risk factors in racial/ethnic minority population case∗ - p. 234 45. Case report - p. 235 46. Introduction - p. 235 47. Concluding remarks - p. 237 48. Summary/conclusion - p. 239 49. Case 9 Alzheimer's/ethnic disparities genetic risk factor and Alzheimer's disease among Ashkenazi Jews∗ - p. 241 50. Case report - p. 241 51. Introduction - p. 242 52. Concluding remarks - p. 242 53. Case 10 Prevalence of early Alzheimer's disease in United States, accounting for racial and ethnic diversity∗ - p. 243 54. Concluding remarks - p. 244 55. Case 11 Alzheimer's disease and Alzheimer's disease-related dementias in hispanics: Identifying influential factors∗ - p. 244 56. Objectives - p. 245 57. Risk factors contributing to high prevalence of AD/ADRD in hispanic population - p. 245 58. Interventions to overcome the barriers of AD/ADRD assessments and research participation in Hispanic Americans population - p. 253 59. Concluding remarks - p. 254 60. Case 12 Association of race and ethnicity with dementia∗ - p. 258 61. Objectives - p. 259 62. Introduction - p. 259 63. Key findings - p. 260 64. Index - p. 265
Differentiating Factors in Alzheimer’s Disease: Gender, Ethnicity, Clinical and Treatment addresses the question why women differ from men in terms of their risk factors and how Alzheimer's disease can be prevented at the molecular level. This book reviews the epidemiology of Alzheimer's disease describing the differences in men's and women's brain anatomy and biochemistry that may account for why women are more likely to develop Alzheimer's disease. The authors offer actions that could help to prevent or slow the progression of Alzheimer's disease in addition to discussing the most recent pharmacological treatments.
1. Introduction - p. xv 2. Chapter One. Alzheimer's disease: Epidemiological and genetical approaches - p. 1 3. Chapter Two. Sex and gender differences in Alzheimer's disease - p. 15 4. Chapter Three. Alzheimer's anatomical and pathophysiological approaches - p. 25 5. Chapter Four. How and why your gender impacts your risk for dementia? - p. 37 6. Chapter Five. How and why your race impacts your risk of dementia? - p. 53 7. Chapter Six. Alzheimer's disease: Pharmacological approaches - p. 73 8. Chapter Seven. Alzheimer's disease: Interventions and preventive approaches - p. 91 9. Chapter Eight. Alzheimer's disease: Interventions, preventive, and treatment/alternative medicine and nutritional approaches - p. 113 10. Chapter Nine. Alcohol and Alzheimer's—Is there a link? - p. 129 11. Chapter Ten. Clinical investigation cases studies and critical thinking problem approaches - p. 175 12. Introduction - p. 175 13. Case 1 Diagnostic application of early-onset Alzheimer's disease (AD)∗ - p. 176 14. Objectives - p. 176 15. Case - p. 176 16. Case 2 Magnetic resonance imaging of early-onset alzheimer disease (EOAD) for AD patients with a Novel Presenilin 2 mutation∗ - p. 180 17. Case report - p. 181 18. Case 3 A precision medicine approach to multifactorial dementia and Alzheimer's disease (AD)∗ - p. 187 19. Introduction - p. 188 20. Case presentation (Ross et al., 2021) - p. 189 21. Concluding remarks - p. 202 22. Case 4 Alzheimer's dementia∗ - p. 204 23. Case report - p. 205 24. Questions - p. 206 25. Answers to the questions - p. 206 26. Clinical approach - p. 206 27. Answers - p. 208 28. Case 5 Rare genetic resilience of autosomal-dominant Alzheimer's disease PSEN1- E280A mutation in mid-age male Alzheimer's disease (AD) patient versus female AD patient∗ - p. 208 29. Case study - p. 208 30. Case report - p. 209 31. Analysis of key findings of the article - p. 211 32. Concluding remarks - p. 215 33. Case 6 Early diagnosis of AD is a must for effective treatment protocol∗ - p. 218 34. Case study - p. 218 35. Case report - p. 219 36. Case analysis for key findings - p. 220 37. Concluding remarks - p. 222 38. Case 7 Biomarkers: Biology-based criteria for the diagnosis of Alzheimer's disease∗ - p. 224 39. Objectives - p. 224 40. Key highlights - p. 224 41. Key principles - p. 225 42. Alzheimer's biomarkers categorization - p. 226 43. Concluding remarks - p. 232 44. Case 8 Alzheimer's genetic risk factors in racial/ethnic minority population case∗ - p. 234 45. Case report - p. 235 46. Introduction - p. 235 47. Concluding remarks - p. 237 48. Summary/conclusion - p. 239 49. Case 9 Alzheimer's/ethnic disparities genetic risk factor and Alzheimer's disease among Ashkenazi Jews∗ - p. 241 50. Case report - p. 241 51. Introduction - p. 242 52. Concluding remarks - p. 242 53. Case 10 Prevalence of early Alzheimer's disease in United States, accounting for racial and ethnic diversity∗ - p. 243 54. Concluding remarks - p. 244 55. Case 11 Alzheimer's disease and Alzheimer's disease-related dementias in hispanics: Identifying influential factors∗ - p. 244 56. Objectives - p. 245 57. Risk factors contributing to high prevalence of AD/ADRD in hispanic population - p. 245 58. Interventions to overcome the barriers of AD/ADRD assessments and research participation in Hispanic Americans population - p. 253 59. Concluding remarks - p. 254 60. Case 12 Association of race and ethnicity with dementia∗ - p. 258 61. Objectives - p. 259 62. Introduction - p. 259 63. Key findings - p. 260 64. Index - p. 265
