DNA Interactions With Drugs and Other Small Ligands: Single Molecule Approaches and Techniques provides the reader with all the main information, a "state-of-the-art" of sorts and an overall review of the field. There is no other book currently available that covers all these subjects together. On the contrary, the different subjects that are developed in this book are currently scattered in journal articles and other books.
1. Chapter 1 : Introduction - p. Page xii 2. Chapter 2 : Intermolecular interactions and DNA solutions - p. Page 5 3. Chapter 3 : DNA ligands - p. Page 22 4. Chapter 4 : Chemical equilibrium in the DNA-ligand interactions: binding isotherms - p. Page 38 5. Chapter 5 : Kinetics in the DNA-ligand interactions - p. Page 53 6. Chapter 6 : Polymers and biopolymers - p. Page 61 7. Chapter 7 : Single molecule techniques - p. Page 99 8. Chapter 8 : Bulk techniques - p. Page 123 9. Chapter 9 : Single molecule force spectroscopy of DNA-ligand complexes in the entropic regime - p. Page 133 10. Chapter 10 : Single molecule force spectroscopy of DNA-ligand complexes in the enthalpic (elastic) regime - p. Page 182 11. Appendix A : Derivation of the equilibrium quantities and force-extension curve (FEC) of the worm-like chain (WLC) model - p. Page 198 12. Appendix B : A protocol to prepare DNA samples for single molecule force spectroscopy assays - p. Page 208 13. Appendix C : An algorithm to perform the persistence and contour length fittings of DNA-ligand complexes - p. Page 212 14. Bibliography - p. Page 213 15. Index - p. Page 213
DNA Interactions With Drugs and Other Small Ligands: Single Molecule Approaches and Techniques provides the reader with all the main information, a "state-of-the-art" of sorts and an overall review of the field. There is no other book currently available that covers all these subjects together. On the contrary, the different subjects that are developed in this book are currently scattered in journal articles and other books.
1. Chapter 1 : Introduction - p. Page xii 2. Chapter 2 : Intermolecular interactions and DNA solutions - p. Page 5 3. Chapter 3 : DNA ligands - p. Page 22 4. Chapter 4 : Chemical equilibrium in the DNA-ligand interactions: binding isotherms - p. Page 38 5. Chapter 5 : Kinetics in the DNA-ligand interactions - p. Page 53 6. Chapter 6 : Polymers and biopolymers - p. Page 61 7. Chapter 7 : Single molecule techniques - p. Page 99 8. Chapter 8 : Bulk techniques - p. Page 123 9. Chapter 9 : Single molecule force spectroscopy of DNA-ligand complexes in the entropic regime - p. Page 133 10. Chapter 10 : Single molecule force spectroscopy of DNA-ligand complexes in the enthalpic (elastic) regime - p. Page 182 11. Appendix A : Derivation of the equilibrium quantities and force-extension curve (FEC) of the worm-like chain (WLC) model - p. Page 198 12. Appendix B : A protocol to prepare DNA samples for single molecule force spectroscopy assays - p. Page 208 13. Appendix C : An algorithm to perform the persistence and contour length fittings of DNA-ligand complexes - p. Page 212 14. Bibliography - p. Page 213 15. Index - p. Page 213
