Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way. The book covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics.
Each subsequent chapter covers drug delivery systems dedicated to metabolic diseases caused by disturbances in protein, lipid, carbohydrate and hormone metabolism. Then, it moves on to cover lysosomal storage disorders and applications of phytopharmaceuticals in this context. This is the perfect reference for researchers in pharmaceutical science who are interested in developing new treatments for metabolic diseases.
1. Chapter 1 : Introduction to metabolic disorders - p. Page xi 2. Chapter 2 : Cellular and molecular mechanisms involved in metabolic disorders - p. Page 17 3. Chapter 3 : Current practices in drug delivery for metabolic disorders - p. Page 26 4. Chapter 4 : Recent developments in the treatment of amyloidosis - p. Page 41 5. Chapter 5 : Advanced drug delivery systems targeting to improve therapeutic outcomes in porphyria - p. Page 59 6. Chapter 6 : Advanced drug delivery systems targeting kwashiorkor involving a disturbance in protein metabolism - p. Page 76 7. Chapter 7 : Advanced drug delivery systems targeting metabolic disorders: erythropoietic protoporphyria - p. Page 83 8. Chapter 8 : Combating atherosclerosis with nanodrug delivery approaches: from bench side to commercialization - p. Page 91 9. Chapter 9 : Advanced drug delivery systems in the management of Gaucher disease - p. Page 131 10. Chapter 10 : Advanced drug delivery systems focusing the metabolic disorders due to deregulation of lipid metabolism: Niemann Pick Disease and Letterer-Siwe disease - p. Page 146 11. Chapter 11 : Genetic disease and Niemann-Pick disorders: novel treatments and drug delivery systems - p. Page 159 12. Chapter 12 : Novel 3D printing drug delivery system for the prevention and treatment of Atherosclerosis - p. Page 174 13. Chapter 13 : Advanced drug delivery systems to treat Huntington’s disease: challenges and opportunities - p. Page 187 14. Chapter 14 : Advanced drug delivery systems for targeting obesity - p. Page 202 15. Chapter 15 : Advanced drug delivery systems for treatment of diabetes mellitus - p. Page 213 16. Chapter 16 : Advanced drug delivery system in the treatment of hyperglycemia and hypoglycemia - p. Page 229 17. Chapter 17 : Emerging drug delivery in the treatment of hyperpituitarism and hypopituitarism - p. Page 245 18. Chapter 18 : Advance drug delivery systems targeting hypoparathyroidism and hyperparathyroidism - p. Page 256 19. Chapter 19 : An update on the development of advanced drug delivery systems for the treatment of hyperthyroidism - p. Page 266 20. Chapter 20 : Advanced drug delivery systems involving lysosomal storage disorders for Schinder disease and other disorders - p. Page 277 21. Chapter 21 : Advanced drug delivery systems involving lysosomal storage disorders for Fabry disease - p. Page 293 22. Chapter 22 : Drug delivery systems in Krabbe disease—present and prospective approaches - p. Page 309 23. Chapter 23 : Strategies to combat Tay-Sachs disease - p. Page 332 24. Chapter 24 : Sandhoff disease: pathology and advanced treatment strategies - p. Page 347 25. Chapter 25 : Nanomaterials-based drug delivery approaches for metabolic disorders - p. Page 357 26. Chapter 26 : Eye in metabolic disorders: manifestations and drug delivery systems - p. Page 367 27. Chapter 27 : Advanced drug delivery systems involving mitochondrial disorders - p. Page 404 28. Chapter 28 : Applications of phytopharmaceuticals in targeting metabolic disorders - p. Page 420 29. Chapter 29 : Phytonanoparticles toward the treatment of diabetes - p. Page 430 30. Chapter 30 : Role of nutraceuticals in metabolic syndrome - p. Page 453 31. Chapter 31 : Latest advances of phytomedicine in drug delivery systems for targeting metabolic disorders - p. Page 465 32. Chapter 32 : Clinical trials, future prospects and challenges of drug delivery in combating metabolic disorders - p. Page 478 33. Index - p. Page 488
Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way. The book covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics.
Each subsequent chapter covers drug delivery systems dedicated to metabolic diseases caused by disturbances in protein, lipid, carbohydrate and hormone metabolism. Then, it moves on to cover lysosomal storage disorders and applications of phytopharmaceuticals in this context. This is the perfect reference for researchers in pharmaceutical science who are interested in developing new treatments for metabolic diseases.
1. Chapter 1 : Introduction to metabolic disorders - p. Page xi 2. Chapter 2 : Cellular and molecular mechanisms involved in metabolic disorders - p. Page 17 3. Chapter 3 : Current practices in drug delivery for metabolic disorders - p. Page 26 4. Chapter 4 : Recent developments in the treatment of amyloidosis - p. Page 41 5. Chapter 5 : Advanced drug delivery systems targeting to improve therapeutic outcomes in porphyria - p. Page 59 6. Chapter 6 : Advanced drug delivery systems targeting kwashiorkor involving a disturbance in protein metabolism - p. Page 76 7. Chapter 7 : Advanced drug delivery systems targeting metabolic disorders: erythropoietic protoporphyria - p. Page 83 8. Chapter 8 : Combating atherosclerosis with nanodrug delivery approaches: from bench side to commercialization - p. Page 91 9. Chapter 9 : Advanced drug delivery systems in the management of Gaucher disease - p. Page 131 10. Chapter 10 : Advanced drug delivery systems focusing the metabolic disorders due to deregulation of lipid metabolism: Niemann Pick Disease and Letterer-Siwe disease - p. Page 146 11. Chapter 11 : Genetic disease and Niemann-Pick disorders: novel treatments and drug delivery systems - p. Page 159 12. Chapter 12 : Novel 3D printing drug delivery system for the prevention and treatment of Atherosclerosis - p. Page 174 13. Chapter 13 : Advanced drug delivery systems to treat Huntington’s disease: challenges and opportunities - p. Page 187 14. Chapter 14 : Advanced drug delivery systems for targeting obesity - p. Page 202 15. Chapter 15 : Advanced drug delivery systems for treatment of diabetes mellitus - p. Page 213 16. Chapter 16 : Advanced drug delivery system in the treatment of hyperglycemia and hypoglycemia - p. Page 229 17. Chapter 17 : Emerging drug delivery in the treatment of hyperpituitarism and hypopituitarism - p. Page 245 18. Chapter 18 : Advance drug delivery systems targeting hypoparathyroidism and hyperparathyroidism - p. Page 256 19. Chapter 19 : An update on the development of advanced drug delivery systems for the treatment of hyperthyroidism - p. Page 266 20. Chapter 20 : Advanced drug delivery systems involving lysosomal storage disorders for Schinder disease and other disorders - p. Page 277 21. Chapter 21 : Advanced drug delivery systems involving lysosomal storage disorders for Fabry disease - p. Page 293 22. Chapter 22 : Drug delivery systems in Krabbe disease—present and prospective approaches - p. Page 309 23. Chapter 23 : Strategies to combat Tay-Sachs disease - p. Page 332 24. Chapter 24 : Sandhoff disease: pathology and advanced treatment strategies - p. Page 347 25. Chapter 25 : Nanomaterials-based drug delivery approaches for metabolic disorders - p. Page 357 26. Chapter 26 : Eye in metabolic disorders: manifestations and drug delivery systems - p. Page 367 27. Chapter 27 : Advanced drug delivery systems involving mitochondrial disorders - p. Page 404 28. Chapter 28 : Applications of phytopharmaceuticals in targeting metabolic disorders - p. Page 420 29. Chapter 29 : Phytonanoparticles toward the treatment of diabetes - p. Page 430 30. Chapter 30 : Role of nutraceuticals in metabolic syndrome - p. Page 453 31. Chapter 31 : Latest advances of phytomedicine in drug delivery systems for targeting metabolic disorders - p. Page 465 32. Chapter 32 : Clinical trials, future prospects and challenges of drug delivery in combating metabolic disorders - p. Page 478 33. Index - p. Page 488
