Dr. Pyrsopolous has created a comprehensive review on the most important and timely topics in drug heptatotoxicity. He has arraanged for there to be a full span of very basic articles that discuss drug metabolism, hepatotoxicity, and drug-induced acute liver failure as well as other important articles devoted to clinical manifestations and treatment of drug induced hepatotoxicity; Pathological manifestations of drug induced hepatotoxicity; Drug induced cholestasis; Lipid lowering agents induced hepatotoxicity; Herbal ,complementary and alternative medicine induced liver injury; Antiretroviral and anti - HCV DAA related hepatotoxicity; Antibiotic related hepatotoxicity; Acetaminophen related hepatoxicity; NSAIDS induced hepatoxocity; Chemotherapy induced hepatotoxicity; Anti epileptic induced hepatotoxicity; and steatohepatitis induced by drugs.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 5 6. Preface - p. 6 7. Mechanisms of Drug-induced Liver Injury - p. 7 8. Drug-Induced Cholestasis - p. 14 9. Drug-Induced Steatohepatitis - p. 22 10. Histopathologic Manifestations of Drug-induced Hepatotoxicity - p. 30 11. Clinical Manifestations and Treatment of Drug-induced Hepatotoxicity - p. 39 12. Drug-induced Acute Liver Failure - p. 43 13. Acetaminophen-related Hepatotoxicity - p. 48 14. Hepatotoxicity of Antibiotics - p. 60 15. Nonsteroidal Anti-Inflammatory Drug–Induced Hepatoxicity - p. 80 16. Antiretroviral and Anti–Hepatitis C Virus Direct-Acting Antiviral-Related Hepatotoxicity - p. 86 17. Chemotherapy-Induced Hepatotoxicity - p. 94 18. Drug-Induced Liver Injury from Antiepileptic Drugs - p. 102 19. Lipid-Lowering Agents and Hepatotoxicity - p. 109 20. Liver Injury Induced by Herbal Complementary and Alternative Medicine - p. 117 21. Hepatotoxicity and Drug Interactions in Liver Transplant Candidates and Recipients - p. 129 22. How to Avoid Being Surprised by Hepatotoxicity at the Final Stages of Drug Development and Approval - p. 136 23. Index - p. 147
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Dr. Pyrsopolous has created a comprehensive review on the most important and timely topics in drug heptatotoxicity. He has arraanged for there to be a full span of very basic articles that discuss drug metabolism, hepatotoxicity, and drug-induced acute liver failure as well as other important articles devoted to clinical manifestations and treatment of drug induced hepatotoxicity; Pathological manifestations of drug induced hepatotoxicity; Drug induced cholestasis; Lipid lowering agents induced hepatotoxicity; Herbal ,complementary and alternative medicine induced liver injury; Antiretroviral and anti - HCV DAA related hepatotoxicity; Antibiotic related hepatotoxicity; Acetaminophen related hepatoxicity; NSAIDS induced hepatoxocity; Chemotherapy induced hepatotoxicity; Anti epileptic induced hepatotoxicity; and steatohepatitis induced by drugs.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 5 6. Preface - p. 6 7. Mechanisms of Drug-induced Liver Injury - p. 7 8. Drug-Induced Cholestasis - p. 14 9. Drug-Induced Steatohepatitis - p. 22 10. Histopathologic Manifestations of Drug-induced Hepatotoxicity - p. 30 11. Clinical Manifestations and Treatment of Drug-induced Hepatotoxicity - p. 39 12. Drug-induced Acute Liver Failure - p. 43 13. Acetaminophen-related Hepatotoxicity - p. 48 14. Hepatotoxicity of Antibiotics - p. 60 15. Nonsteroidal Anti-Inflammatory Drug–Induced Hepatoxicity - p. 80 16. Antiretroviral and Anti–Hepatitis C Virus Direct-Acting Antiviral-Related Hepatotoxicity - p. 86 17. Chemotherapy-Induced Hepatotoxicity - p. 94 18. Drug-Induced Liver Injury from Antiepileptic Drugs - p. 102 19. Lipid-Lowering Agents and Hepatotoxicity - p. 109 20. Liver Injury Induced by Herbal Complementary and Alternative Medicine - p. 117 21. Hepatotoxicity and Drug Interactions in Liver Transplant Candidates and Recipients - p. 129 22. How to Avoid Being Surprised by Hepatotoxicity at the Final Stages of Drug Development and Approval - p. 136 23. Index - p. 147
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