Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase inhibitors (DNMTi), Histone deacetylases inhibitors (HDACi), Histone lysine demethylases inhibitors (HDMi), Histone lysine methyltransferases inhibitors (HMTi) and drugs regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally, recent and future developments of the field of epigenetic regulation are explored.
This is a valuable resource for cancer researchers, clinicians, graduate students and several members of biomedical field who are interested in learning about epigenetic regulation methods to reverse chemo-resistance in cancers.
1. Epigenetic Regulation in Overcoming Chemoresistance - p. i 2. Cover - p. i 3. Title Page - p. i 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Cover Image Insert - p. iv 7. Aims and Scope for Series “Cancer Sensitizing Agents for Chemotherapy” - p. vii 8. About the Series Editor - p. ix 9. Aims and Scope of the Volume - p. xi 10. About the Volume Editors - p. xiii 11. Preface - p. xv 12. Contributors - p. xix 13. Chapter 1 The role of epigenetic regulation in cancer - p. 1 14. Chapter 2 DNA methyltransferase inhibitors (DNMTis) as sensitizing agents to overcome chemoresistance - p. 9 15. Chapter 3 Histone deacetylase inhibitors (HDACi), the ongoing epigenetic agents to enhance chemotherapy sensitization - p. 25 16. Chapter 4 Histone lysine demethylase inhibitor (HDMi) as chemo-sensitizing agent - p. 41 17. Chapter 5 Targeting histone lysine methyltransferases for drug sensitization - p. 57 18. Chapter 6 Ribonucleotide base-modifying enzymes and diseases - p. 69 19. Chapter 7 The combination strategy with epigenetic therapy, chemotherapy, and immunotherapy - p. 85 20. Chapter 8 Future epigenetic treatment strategies - p. 103 21. Index - p. 121
Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase inhibitors (DNMTi), Histone deacetylases inhibitors (HDACi), Histone lysine demethylases inhibitors (HDMi), Histone lysine methyltransferases inhibitors (HMTi) and drugs regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally, recent and future developments of the field of epigenetic regulation are explored.
This is a valuable resource for cancer researchers, clinicians, graduate students and several members of biomedical field who are interested in learning about epigenetic regulation methods to reverse chemo-resistance in cancers.
1. Epigenetic Regulation in Overcoming Chemoresistance - p. i 2. Cover - p. i 3. Title Page - p. i 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Cover Image Insert - p. iv 7. Aims and Scope for Series “Cancer Sensitizing Agents for Chemotherapy” - p. vii 8. About the Series Editor - p. ix 9. Aims and Scope of the Volume - p. xi 10. About the Volume Editors - p. xiii 11. Preface - p. xv 12. Contributors - p. xix 13. Chapter 1 The role of epigenetic regulation in cancer - p. 1 14. Chapter 2 DNA methyltransferase inhibitors (DNMTis) as sensitizing agents to overcome chemoresistance - p. 9 15. Chapter 3 Histone deacetylase inhibitors (HDACi), the ongoing epigenetic agents to enhance chemotherapy sensitization - p. 25 16. Chapter 4 Histone lysine demethylase inhibitor (HDMi) as chemo-sensitizing agent - p. 41 17. Chapter 5 Targeting histone lysine methyltransferases for drug sensitization - p. 57 18. Chapter 6 Ribonucleotide base-modifying enzymes and diseases - p. 69 19. Chapter 7 The combination strategy with epigenetic therapy, chemotherapy, and immunotherapy - p. 85 20. Chapter 8 Future epigenetic treatment strategies - p. 103 21. Index - p. 121
