Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches.
1. Essential Guide to Neurodegenerative Disorders - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. Contributors - p. Page v 8. Preface - p. Page xi 9. Acknowledgments - p. Page xii 10. List of Illustrations - p. Page xiii 11. List of Tables - p. Page xiv 12. Chapter 1 : The biochemical pathways of Alzheimer's disease - p. Page xiv 13. Chapter 2 : The blood–brain barrier: Gatekeeper and obstacle in neurodegenerative disorders - p. Page 11 14. Chapter 3 : The aging brain, mitochondria, and neurodegenerative disorders - p. Page 28 15. Chapter 4 : Neuropathology insights: Parkinson's, Alzheimer's and their nexus - p. Page 47 16. Chapter 5 : Neuroinflammation-microglia and neurodegeneration - p. Page 68 17. Chapter 6 : The gut-microbiota and neurodegenerative disorders: What is the interplay? - p. Page 96 18. Chapter 7 : Crosstalk between nutritions and brain neurotransmitters - p. Page 112 19. Chapter 8 : Frontotemporal dementia - p. Page 126 20. Chapter 9 : Diabetes mellitus and neurodegenerative disorders - p. Page 143 21. Chapter 10 : Dairy consumption and the risk of Parkinson's disease - p. Page 158 22. Chapter 11 : The pathophysiology of neurodegenerative diseases: The back effects of oxidative stress and antioxidants system - p. Page 174 23. Chapter 12 : The interplay between tauopathies and neurodegeneration - p. Page 187 24. Chapter 13 : Mechanistic insights into the molecular and cellular basis of Alzheimer's disease - p. Page 208 25. Chapter 14 : Epidemiology and risk factors of Parkinson's disease - p. Page 220 26. Chapter 15 : Decoding Parkinson's disease: A multifaceted approach to diagnosis and biomarker discovery - p. Page 230 27. Chapter 16 : Psychological assessment of patients with Parkinson's disease - p. Page 251 28. Chapter 17 : Non-motor symptoms of Parkinson's disease - p. Page 264 29. Chapter 18 : Blood markers of oxidative stress in patients with amyotrophic lateral sclerosis - p. Page 277 30. Chapter 19 : Dementia in AfrAbia: A bibliometric analysis - p. Page 286 31. Chapter 20 : Molecular genetics of prions - p. Page 303 32. Chapter 21 : Genomics and Parkinson's disease: What is the interplay? - p. Page 314 33. Chapter 22 : Recent aspects in the molecular genetics of Huntington's disease - p. Page 336 34. Chapter 23 : Current trends of computational tools and artificial intelligence in geriatric medicine - p. Page 355 35. Chapter 24 : Emerging nanotechnologies in drug delivery: Insights and regulatory challenges - p. Page 371 36. Chapter 25 : Interplay between food-associated oxidative stress and NDG disorders - p. Page 389 37. Chapter 26 : Nutrition in aging - p. Page 407 38. Chapter 27 : Pharmacotherapy of Alzheimer's disease: A thorny road to success - p. Page 428 39. Chapter 28 : Atypical antipsychotic lumateperone beyond schizophrenia: Seeking clarity in a time of uncertainty - p. Page 452 40. Chapter 29 : The promise of Tele-Dementia: Today's science and tomorrow's trial - p. Page 466 41. Chapter 30 : Potential role of probiotics for neurological disease treatment - p. Page 475 42. Chapter 31 : A new era of nanotechnology applied in neurological disease treatments - p. Page 490 43. Chapter 32 : Stem cell therapy in neurodegenerative disorders - p. Page 512 44. Chapter 33 : Why do we need new therapies for neurodegenerative disorders? - p. Page 564 45. Chapter 34 : Smart foods and neurodegeneration: Exploring future therapeutic avenues - p. Page 583 46. Chapter 35 : Nutrigenomics and Parkinson's disease - p. Page 598 47. Chapter 36 : Gene therapy in neurodegenerative disorders - p. Page 621 48. Index - p. Page 648
Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches.
1. Essential Guide to Neurodegenerative Disorders - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Dedication - p. Page v 7. Contributors - p. Page v 8. Preface - p. Page xi 9. Acknowledgments - p. Page xii 10. List of Illustrations - p. Page xiii 11. List of Tables - p. Page xiv 12. Chapter 1 : The biochemical pathways of Alzheimer's disease - p. Page xiv 13. Chapter 2 : The blood–brain barrier: Gatekeeper and obstacle in neurodegenerative disorders - p. Page 11 14. Chapter 3 : The aging brain, mitochondria, and neurodegenerative disorders - p. Page 28 15. Chapter 4 : Neuropathology insights: Parkinson's, Alzheimer's and their nexus - p. Page 47 16. Chapter 5 : Neuroinflammation-microglia and neurodegeneration - p. Page 68 17. Chapter 6 : The gut-microbiota and neurodegenerative disorders: What is the interplay? - p. Page 96 18. Chapter 7 : Crosstalk between nutritions and brain neurotransmitters - p. Page 112 19. Chapter 8 : Frontotemporal dementia - p. Page 126 20. Chapter 9 : Diabetes mellitus and neurodegenerative disorders - p. Page 143 21. Chapter 10 : Dairy consumption and the risk of Parkinson's disease - p. Page 158 22. Chapter 11 : The pathophysiology of neurodegenerative diseases: The back effects of oxidative stress and antioxidants system - p. Page 174 23. Chapter 12 : The interplay between tauopathies and neurodegeneration - p. Page 187 24. Chapter 13 : Mechanistic insights into the molecular and cellular basis of Alzheimer's disease - p. Page 208 25. Chapter 14 : Epidemiology and risk factors of Parkinson's disease - p. Page 220 26. Chapter 15 : Decoding Parkinson's disease: A multifaceted approach to diagnosis and biomarker discovery - p. Page 230 27. Chapter 16 : Psychological assessment of patients with Parkinson's disease - p. Page 251 28. Chapter 17 : Non-motor symptoms of Parkinson's disease - p. Page 264 29. Chapter 18 : Blood markers of oxidative stress in patients with amyotrophic lateral sclerosis - p. Page 277 30. Chapter 19 : Dementia in AfrAbia: A bibliometric analysis - p. Page 286 31. Chapter 20 : Molecular genetics of prions - p. Page 303 32. Chapter 21 : Genomics and Parkinson's disease: What is the interplay? - p. Page 314 33. Chapter 22 : Recent aspects in the molecular genetics of Huntington's disease - p. Page 336 34. Chapter 23 : Current trends of computational tools and artificial intelligence in geriatric medicine - p. Page 355 35. Chapter 24 : Emerging nanotechnologies in drug delivery: Insights and regulatory challenges - p. Page 371 36. Chapter 25 : Interplay between food-associated oxidative stress and NDG disorders - p. Page 389 37. Chapter 26 : Nutrition in aging - p. Page 407 38. Chapter 27 : Pharmacotherapy of Alzheimer's disease: A thorny road to success - p. Page 428 39. Chapter 28 : Atypical antipsychotic lumateperone beyond schizophrenia: Seeking clarity in a time of uncertainty - p. Page 452 40. Chapter 29 : The promise of Tele-Dementia: Today's science and tomorrow's trial - p. Page 466 41. Chapter 30 : Potential role of probiotics for neurological disease treatment - p. Page 475 42. Chapter 31 : A new era of nanotechnology applied in neurological disease treatments - p. Page 490 43. Chapter 32 : Stem cell therapy in neurodegenerative disorders - p. Page 512 44. Chapter 33 : Why do we need new therapies for neurodegenerative disorders? - p. Page 564 45. Chapter 34 : Smart foods and neurodegeneration: Exploring future therapeutic avenues - p. Page 583 46. Chapter 35 : Nutrigenomics and Parkinson's disease - p. Page 598 47. Chapter 36 : Gene therapy in neurodegenerative disorders - p. Page 621 48. Index - p. Page 648
