Covering pertinent basic science and offering today’s most authoritative guidance on clinical management, Fetal Medicine, 3rd Edition, is a must-have resource for obstetricians and other healthcare professionals involved in care of the fetus. An international team of expert contributors delivers the knowledge and background you need to effectively diagnose and treat fetal disorders – everything from prenatal screening and diagnostic tests to common and rare prenatal conditions, early pregnancy loss, ethical issues, and much more.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Foreword - p. iii 6. Preface - p. iii 7. List of Contributors - p. iii 8. List of Illustrations - p. iii 9. List of Tables - p. iii 10. Section 1: Early Fetal Development - p. iii 11. Chapter 1: Early Concepts and Terminology - p. iii 12. Chapter 2: Cellular Mechanisms and Embryonic Tissues - p. g5 13. Chapter 3: Staging Embryos in Development and the Embryonic Body Plan - p. g22.e1 14. Chapter 4: Teratology - p. g29 15. Chapter 5: Early Pregnancy Failure - p. g37 16. Section 2: The Placenta - p. g46 17. Chapter 6: The Immunology of Implantation - p. g46 18. Chapter 7: Development of the Placenta and Its Circulation - p. g54 19. Chapter 8: Placental Function in Maternofetal Exchange - p. g68 20. Chapter 9: Placental Pathology and Implications for Fetal Medicine - p. g77 21. Section 3: Fetal Physiology and Pathology - p. g86 22. Chapter 10: Development of the Heart and Cardiovascular System in Relation to Cardiac Abnormalities - p. g86 23. Chapter 11: Lung Growth and Maturation - p. g102 24. Chapter 12: Development of the Kidneys and Urinary Tract in Relation to Renal Anomalies - p. g113 25. Chapter 13: The Perinatal Postmortem Examination - p. g120 26. Section 4: Epidemiology - p. g130 27. Chapter 14: Epidemiologic and Research Methods in Fetal Medicine - p. g130 28. Section 5: Ethics - p. g137 29. Chapter 15: Ethical Issues in Maternal-Fetal Medicine - p. g137 30. Section 6: Prenatal Screening and Diagnosis - p. g147 31. Chapter 16: Principles of Screening - p. g147 32. Chapter 17: Conveying Information About Screening and Diagnosis - p. g153 33. Chapter 18: Ultrasound and Biochemical Screening for Fetal Aneuploidy - p. g160 34. Chapter 19: Ultrasound Screening for Fetal Abnormalities in the First Trimester - p. g175 35. Chapter 20: Evidence for Routine Ultrasound Screening for Fetal Abnormalities in the Second and Third Trimesters - p. g193 36. Chapter 21: Noninvasive Screening for Cytogenetic Disorders (Fetal Aneuploidy Including Microdeletions) - p. g201 37. Chapter 22: Noninvasive Prenatal Diagnosis for Single-Gene Disorders - p. g212 38. Chapter 23: Invasive Diagnostic Procedures - p. g224 39. Chapter 24: Prenatal Diagnosis of Chromosome Abnormalities - p. g232 40. Chapter 25: Advances in Molecular Genetics Including Fetal Sequencing - p. g246 41. Chapter 26: Expanded Carrier Screening - p. g253 42. Chapter 27: Prenatal Screening for Thalassemias - p. g262 43. Section 7: Diagnosis and Management of Fetal Malformations - p. g273 44. Chapter 28: Sonography of the Fetal Central Nervous System - p. g273 45. Chapter 29: The Heart - p. g304 46. Chapter 30: Fetal Lung Lesions - p. g323 47. Chapter 31: Congenital Diaphragmatic Hernia - p. g331 48. Chapter 32: Abdomen - p. g339 49. Chapter 33: Kidney and Urinary Tract Disorders - p. g350 50. Chapter 34: Diagnosis and Management of Fetal Skeletal Abnormalities - p. g372 51. Chapter 35: Diagnosis and Management of Abnormalities of the Face - p. g399 52. Chapter 36: Fetal Hydrops - p. g423 53. Chapter 37: Fetal Tumours - p. g442 54. Chapter 38: Open Fetal Surgery - p. g453 55. Section 8: Diagnosis and Management of Other Fetal Conditions - p. g467 56. Chapter 39: Fetal Growth and Growth Restriction - p. g467 57. Chapter 40: Haemolytic Disease of the Fetus and Newborn - p. g483 58. Chapter 41: Fetal Platelet Disorders - p. g496 59. Chapter 42: Fetal Infections - p. g507 60. Chapter 43: Disorders of Amniotic Fluid - p. g525 61. Chapter 44: Multiple Pregnancy - p. g531 62. Chapter 45: In Utero Stem Cell Transplantation - p. g553 63. Chapter 46: Fetal Gene Therapy - p. g558 64. Chapter 47: The Developmental Origins of Health and Disease - p. g571 65. Section 9: Interface of Maternal, Fetal and Neonatal Medicine - p. g579 66. Chapter 48: Pharmacokinetics and Pharmacodynamics - p. g579 67. Chapter 49: Neonatal Management and Outcome in Extreme Prematurity - p. g586 68. Self-Assessment - p. g595 69. Index - p. ge45
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Covering pertinent basic science and offering today’s most authoritative guidance on clinical management, Fetal Medicine, 3rd Edition, is a must-have resource for obstetricians and other healthcare professionals involved in care of the fetus. An international team of expert contributors delivers the knowledge and background you need to effectively diagnose and treat fetal disorders – everything from prenatal screening and diagnostic tests to common and rare prenatal conditions, early pregnancy loss, ethical issues, and much more.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Foreword - p. iii 6. Preface - p. iii 7. List of Contributors - p. iii 8. List of Illustrations - p. iii 9. List of Tables - p. iii 10. Section 1: Early Fetal Development - p. iii 11. Chapter 1: Early Concepts and Terminology - p. iii 12. Chapter 2: Cellular Mechanisms and Embryonic Tissues - p. g5 13. Chapter 3: Staging Embryos in Development and the Embryonic Body Plan - p. g22.e1 14. Chapter 4: Teratology - p. g29 15. Chapter 5: Early Pregnancy Failure - p. g37 16. Section 2: The Placenta - p. g46 17. Chapter 6: The Immunology of Implantation - p. g46 18. Chapter 7: Development of the Placenta and Its Circulation - p. g54 19. Chapter 8: Placental Function in Maternofetal Exchange - p. g68 20. Chapter 9: Placental Pathology and Implications for Fetal Medicine - p. g77 21. Section 3: Fetal Physiology and Pathology - p. g86 22. Chapter 10: Development of the Heart and Cardiovascular System in Relation to Cardiac Abnormalities - p. g86 23. Chapter 11: Lung Growth and Maturation - p. g102 24. Chapter 12: Development of the Kidneys and Urinary Tract in Relation to Renal Anomalies - p. g113 25. Chapter 13: The Perinatal Postmortem Examination - p. g120 26. Section 4: Epidemiology - p. g130 27. Chapter 14: Epidemiologic and Research Methods in Fetal Medicine - p. g130 28. Section 5: Ethics - p. g137 29. Chapter 15: Ethical Issues in Maternal-Fetal Medicine - p. g137 30. Section 6: Prenatal Screening and Diagnosis - p. g147 31. Chapter 16: Principles of Screening - p. g147 32. Chapter 17: Conveying Information About Screening and Diagnosis - p. g153 33. Chapter 18: Ultrasound and Biochemical Screening for Fetal Aneuploidy - p. g160 34. Chapter 19: Ultrasound Screening for Fetal Abnormalities in the First Trimester - p. g175 35. Chapter 20: Evidence for Routine Ultrasound Screening for Fetal Abnormalities in the Second and Third Trimesters - p. g193 36. Chapter 21: Noninvasive Screening for Cytogenetic Disorders (Fetal Aneuploidy Including Microdeletions) - p. g201 37. Chapter 22: Noninvasive Prenatal Diagnosis for Single-Gene Disorders - p. g212 38. Chapter 23: Invasive Diagnostic Procedures - p. g224 39. Chapter 24: Prenatal Diagnosis of Chromosome Abnormalities - p. g232 40. Chapter 25: Advances in Molecular Genetics Including Fetal Sequencing - p. g246 41. Chapter 26: Expanded Carrier Screening - p. g253 42. Chapter 27: Prenatal Screening for Thalassemias - p. g262 43. Section 7: Diagnosis and Management of Fetal Malformations - p. g273 44. Chapter 28: Sonography of the Fetal Central Nervous System - p. g273 45. Chapter 29: The Heart - p. g304 46. Chapter 30: Fetal Lung Lesions - p. g323 47. Chapter 31: Congenital Diaphragmatic Hernia - p. g331 48. Chapter 32: Abdomen - p. g339 49. Chapter 33: Kidney and Urinary Tract Disorders - p. g350 50. Chapter 34: Diagnosis and Management of Fetal Skeletal Abnormalities - p. g372 51. Chapter 35: Diagnosis and Management of Abnormalities of the Face - p. g399 52. Chapter 36: Fetal Hydrops - p. g423 53. Chapter 37: Fetal Tumours - p. g442 54. Chapter 38: Open Fetal Surgery - p. g453 55. Section 8: Diagnosis and Management of Other Fetal Conditions - p. g467 56. Chapter 39: Fetal Growth and Growth Restriction - p. g467 57. Chapter 40: Haemolytic Disease of the Fetus and Newborn - p. g483 58. Chapter 41: Fetal Platelet Disorders - p. g496 59. Chapter 42: Fetal Infections - p. g507 60. Chapter 43: Disorders of Amniotic Fluid - p. g525 61. Chapter 44: Multiple Pregnancy - p. g531 62. Chapter 45: In Utero Stem Cell Transplantation - p. g553 63. Chapter 46: Fetal Gene Therapy - p. g558 64. Chapter 47: The Developmental Origins of Health and Disease - p. g571 65. Section 9: Interface of Maternal, Fetal and Neonatal Medicine - p. g579 66. Chapter 48: Pharmacokinetics and Pharmacodynamics - p. g579 67. Chapter 49: Neonatal Management and Outcome in Extreme Prematurity - p. g586 68. Self-Assessment - p. g595 69. Index - p. ge45
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