Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative diseases, and infectious diseases that affect the brain. Fundamental of Brain Organoids for Neurological Diseases provides a practical resource for researchers on how to utilize and apply brain organoids. This book is organized into nine distinct sections, guiding the reader through each step from advanced overview of what organoids are to the use of brain organoids in various neurodevelopmental disorders and neurodegenerative diseases. In later sections, this book reviews the necessary methods involved in organoid development including the elements and challenges involved. This book will serve as a valuable tool for researchers, helping to advance the understanding of brain biology and disease mechanisms.
1. Chapter 2 A brief introduction to neurodevelopmental disorders - p. 35 2. Chapter 3 Use of brain organoids for autism - p. 57 3. Chapter 4 Role of brain organoids in Rett syndrome - p. 83 4. Chapter 5 Brain organoids in bipolar disorder: Unraveling mechanisms and therapeutic approaches - p. 95 5. Chapter 6 Ongoing clinical trials on use of brain organoids for neurodevelopmental disorders - p. 113 6. Section III Neurodegenerative diseases - p. 139 7. Chapter 7 An overview of neurodegenerative diseases - p. 141 8. Chapter 8 Use of brain organoids for Parkinson's disease and Alzheimer's diseases - p. 161 9. Chapter 9 Application of brain organoids in Huntington's disease - p. 183 10. Chapter 10 Use of brain organoids for neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, Huntington's disease, etc.) - p. 201 11. Section IV Methods involved in organoids development - p. 221 12. Chapter 11 How human-induced pluripotent stem cells are derived into organoids - p. 223 13. Chapter 12 Elements required and days involved in organoid generation - p. 247 14. Section V Application and advancement of brain organoids - p. 263 15. Chapter 13 Brain organoids – Challenges while constructing organoids - p. 265 16. Chapter 14 Existing drug targeting and research using brain organoids - p. 279 17. Section VI Ethical consideration while conducting organoids research - p. 311 18. Chapter 15 Ethical considerations while conducting organoids research - p. 313 19. Section VII Future perspective and concluding remarks - p. 321 20. Chapter 16 Future directions and conclusion - p. 323 21. Index - p. 337
Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative diseases, and infectious diseases that affect the brain. Fundamental of Brain Organoids for Neurological Diseases provides a practical resource for researchers on how to utilize and apply brain organoids. This book is organized into nine distinct sections, guiding the reader through each step from advanced overview of what organoids are to the use of brain organoids in various neurodevelopmental disorders and neurodegenerative diseases. In later sections, this book reviews the necessary methods involved in organoid development including the elements and challenges involved. This book will serve as a valuable tool for researchers, helping to advance the understanding of brain biology and disease mechanisms.
1. Chapter 2 A brief introduction to neurodevelopmental disorders - p. 35 2. Chapter 3 Use of brain organoids for autism - p. 57 3. Chapter 4 Role of brain organoids in Rett syndrome - p. 83 4. Chapter 5 Brain organoids in bipolar disorder: Unraveling mechanisms and therapeutic approaches - p. 95 5. Chapter 6 Ongoing clinical trials on use of brain organoids for neurodevelopmental disorders - p. 113 6. Section III Neurodegenerative diseases - p. 139 7. Chapter 7 An overview of neurodegenerative diseases - p. 141 8. Chapter 8 Use of brain organoids for Parkinson's disease and Alzheimer's diseases - p. 161 9. Chapter 9 Application of brain organoids in Huntington's disease - p. 183 10. Chapter 10 Use of brain organoids for neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, Huntington's disease, etc.) - p. 201 11. Section IV Methods involved in organoids development - p. 221 12. Chapter 11 How human-induced pluripotent stem cells are derived into organoids - p. 223 13. Chapter 12 Elements required and days involved in organoid generation - p. 247 14. Section V Application and advancement of brain organoids - p. 263 15. Chapter 13 Brain organoids – Challenges while constructing organoids - p. 265 16. Chapter 14 Existing drug targeting and research using brain organoids - p. 279 17. Section VI Ethical consideration while conducting organoids research - p. 311 18. Chapter 15 Ethical considerations while conducting organoids research - p. 313 19. Section VII Future perspective and concluding remarks - p. 321 20. Chapter 16 Future directions and conclusion - p. 323 21. Index - p. 337
