Fundamentals of Translational Tissue Engineering explores the practical dimensions of tissue engineering (TE), outlining the intricate path of development of tissue engineered products. The book navigates the reader through the fundamental aspects and challenges in TE, equipping the reader with insights crucial to comprehending the journey a tissue engineered product traverses on its way to clinical translation. The first section, Material Sciences, provides the reader with a general overview covering the basics of scaffolds, biomaterials and techniques, while the larger, second section, Biological and Clinical Aspects, discussing the biological perspectives relating to tissue engineering.
This is a multi-disciplinary work that will be ideal for audiences of varying levels of expertise, from the novice exploring fundamental concepts or the seasoned professionals seeking comprehensive information, readers of all backgrounds will be able to access and benefit from this tailored approach.
1. Chapter 1. Introduction to translational tissue engineering - p. 3 2. Chapter 2. Scaffold integration: extracellular matrices and cellular interfaces - p. 19 3. Chapter 3. Tissue engineering: methods for scaffolds to extracellular matrix and scaffold to cell interaction - p. 31 4. Chapter 4. Advances in biomanufacturing techniques, biomaterials, and stem cells for tissue engineering - p. 37 5. Chapter 5. Interactions of tooth-derived stem cells with dental regenerative scaffolds - p. 51 6. Chapter 6. Growth and differentiation of mammalian embryonic stem cells on three-dimensional nanofibrilar surfaces - p. 69 7. Chapter 7. Silk routes to healing: engineering biomaterials for mesenchymal stem cell guidance in bone tissue remodeling and repair - p. 79 8. Chapter 8. Bioinspired scaffolds as ideal platform in engineering artificial organs and tumor microenvironment: importance in regenerative and reproductive medicine - p. 93 9. Chapter 9. Nonmedical applications of biomaterials - p. 119 10. Section II: Biological aspects of tissue engineering - p. S131 11. Chapter 10. Quantitative in vitro bioassays for scaffold evaluation - p. 133 12. Chapter 11. In vitro platforms for advancing tissue engineering research - p. 147 13. Chapter 12. Harnessing in vitro models and assays for tissue engineering - p. 167 14. Chapter 13. Precision in vitro tools for tissue engineering applications - p. 187 15. Chapter 14. In vivo models for tissue engineering - p. 195 16. Chapter 15. Comprehending the role of in vivo models in tissue engineering - p. 207 17. Chapter 16. Animals as preclinical models for tissue engineering in retina - p. 215 18. Chapter 17. Circadian mechanisms and the importance of biological timing in tissue engineering - p. 221 19. Chapter 18. Tissue engineering strategies in retina - p. 229 20. Section III: Biosensors in tissue engineering - p. S239 21. Chapter 19. Biomaterial-based biosensors - p. 241 22. Chapter 20. Functional Biomaterials for Biosensing Technologies - p. 273 23. Chapter 21. Electroconductive hydrogels in tissue and regenerative engineering - p. 287 24. Chapter 22. Advanced biosensors developed using biomaterials at macro, micro, and nanoscale for tissue engineering applications - p. 301 25. Section IV: Clinical aspects of tissue engineering - p. S315 26. Chapter 23. Patents on biomaterials - p. 317 27. Chapter 24. Challenges in clinical translation of laboratory discoveries of tissue engineered products - p. 327 28. Chapter 25. Clinical trials documentation in nanomaterials and scaffolds - p. 347 29. Chapter 26. Clinical trial guidelines for tissue engineering - p. 357 30. Chapter 27. Early detection of Parkinson’s disease using multimodal information - p. 377 31. Chapter 28. Regulatory aspects of tissue engineering - p. 385 32. Chapter 29. Regulatory pathways for stem cell and tissue engineering in cancer therapy - p. 393 33. Chapter 30. Social issues regarding organ donation - p. 413 34. Abbreviations - p. 425 35. Index - p. 429
Fundamentals of Translational Tissue Engineering explores the practical dimensions of tissue engineering (TE), outlining the intricate path of development of tissue engineered products. The book navigates the reader through the fundamental aspects and challenges in TE, equipping the reader with insights crucial to comprehending the journey a tissue engineered product traverses on its way to clinical translation. The first section, Material Sciences, provides the reader with a general overview covering the basics of scaffolds, biomaterials and techniques, while the larger, second section, Biological and Clinical Aspects, discussing the biological perspectives relating to tissue engineering.
This is a multi-disciplinary work that will be ideal for audiences of varying levels of expertise, from the novice exploring fundamental concepts or the seasoned professionals seeking comprehensive information, readers of all backgrounds will be able to access and benefit from this tailored approach.
1. Chapter 1. Introduction to translational tissue engineering - p. 3 2. Chapter 2. Scaffold integration: extracellular matrices and cellular interfaces - p. 19 3. Chapter 3. Tissue engineering: methods for scaffolds to extracellular matrix and scaffold to cell interaction - p. 31 4. Chapter 4. Advances in biomanufacturing techniques, biomaterials, and stem cells for tissue engineering - p. 37 5. Chapter 5. Interactions of tooth-derived stem cells with dental regenerative scaffolds - p. 51 6. Chapter 6. Growth and differentiation of mammalian embryonic stem cells on three-dimensional nanofibrilar surfaces - p. 69 7. Chapter 7. Silk routes to healing: engineering biomaterials for mesenchymal stem cell guidance in bone tissue remodeling and repair - p. 79 8. Chapter 8. Bioinspired scaffolds as ideal platform in engineering artificial organs and tumor microenvironment: importance in regenerative and reproductive medicine - p. 93 9. Chapter 9. Nonmedical applications of biomaterials - p. 119 10. Section II: Biological aspects of tissue engineering - p. S131 11. Chapter 10. Quantitative in vitro bioassays for scaffold evaluation - p. 133 12. Chapter 11. In vitro platforms for advancing tissue engineering research - p. 147 13. Chapter 12. Harnessing in vitro models and assays for tissue engineering - p. 167 14. Chapter 13. Precision in vitro tools for tissue engineering applications - p. 187 15. Chapter 14. In vivo models for tissue engineering - p. 195 16. Chapter 15. Comprehending the role of in vivo models in tissue engineering - p. 207 17. Chapter 16. Animals as preclinical models for tissue engineering in retina - p. 215 18. Chapter 17. Circadian mechanisms and the importance of biological timing in tissue engineering - p. 221 19. Chapter 18. Tissue engineering strategies in retina - p. 229 20. Section III: Biosensors in tissue engineering - p. S239 21. Chapter 19. Biomaterial-based biosensors - p. 241 22. Chapter 20. Functional Biomaterials for Biosensing Technologies - p. 273 23. Chapter 21. Electroconductive hydrogels in tissue and regenerative engineering - p. 287 24. Chapter 22. Advanced biosensors developed using biomaterials at macro, micro, and nanoscale for tissue engineering applications - p. 301 25. Section IV: Clinical aspects of tissue engineering - p. S315 26. Chapter 23. Patents on biomaterials - p. 317 27. Chapter 24. Challenges in clinical translation of laboratory discoveries of tissue engineered products - p. 327 28. Chapter 25. Clinical trials documentation in nanomaterials and scaffolds - p. 347 29. Chapter 26. Clinical trial guidelines for tissue engineering - p. 357 30. Chapter 27. Early detection of Parkinson’s disease using multimodal information - p. 377 31. Chapter 28. Regulatory aspects of tissue engineering - p. 385 32. Chapter 29. Regulatory pathways for stem cell and tissue engineering in cancer therapy - p. 393 33. Chapter 30. Social issues regarding organ donation - p. 413 34. Abbreviations - p. 425 35. Index - p. 429
