Now fully revised to include recent advances in the field, the third edition of Gastrointestinal and Liver Pathology Pathology, a volume in the Foundations in Diagnostic Pathology series, is an essential foundation text for residents and pathologists. The popular template format makes it easy to use, and new information throughout brings you up to date with what’s new in the field, including advances in molecular diagnostic testing and new diagnostic biomarkers. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice.
Key features of this practical text include:
A consistent, user-friendly format that explores each entity's clinical features, gross and microscopic findings, ancillary studies, differential diagnoses, and prognostic and therapeutic considerations.
A focus on specific features of selected neoplastic and non-neoplastic entities, including broad and in-depth differential diagnoses.
Clinical information on treatment and prognosis, enabling you to better understand the clinical implications of the diagnosis.
Nearly 1,000 full-color, high-quality illustrations with extensive figure legends, as well as abundant boxes and tables throughout.
What’s NEW in this edition:
Advances in molecular diagnostic testing and its capabilities and limitations, including targeted/personalized medicine.
New diagnostic biomarkers and their utility in differential diagnosis, newly described variants, and new histologic entities.
The latest TNM staging and WHO classification systems.
New co-editors Drs. Amitabh Srivastava and Daniela S. Allende lead a team of expert, internationally recognized pathologists who keep you up to date with the latest information in the field.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. iv 6. Contributors - p. vii 7. Foreword - p. ix 8. Preface - p. ix 9. Acknowledgments - p. xiii 10. 1. Non-Neoplastic Disorders of the Esophagus - p. 1 11. 2. Tumors of the Esophagus - p. 29 12. 3. Non-Neoplastic Disorders of the Stomach - p. 53 13. 4. Epithelial Polyps and Neoplasms of the Stomach - p. 91 14. 5. Non-Neoplastic and Inflammatory Disorders of the Small Bowel - p. 119 15. 6. Neoplasms of the Small Intestine - p. 151 16. 7. Gastrointestinal Mesenchymal Tumors - p. 169 17. 8. Non-Neoplastic and Neoplastic Disorders of the Appendix - p. 211 18. 9. Infectious Diseases of the Gastrointestinal Tract - p. 243 19. 10. Non-neoplastic Disorders of the Colon - p. 299 20. 11. Gastrointestinal Polyposis Syndromes - p. 337 21. 12. Epithelial Neoplasms of the Colorectum - p. 363 22. 13. Molecular Testing of Gastrointestinal Neoplasms - p. 395 23. 14. Pathology of the Anal Canal - p. 407 24. 15. Pathology of the Gallbladder and Extrahepatic Bile Ducts - p. 436 25. 16. Non-Neoplastic and Neoplastic Pathology of the Pancreas - p. 455 26. 17. Non-Neoplastic Disorders of the Liver - p. 489 27. Major Histologic Patterns of Injury - p. 489 28. Acute Hepatitis Pattern of Injury - p. 489 29. Acute Viral (Hepatotropic) Hepatitis - p. 491 30. Clinical Features - p. 491 31. Nonhepatotropic Viral Infections - p. 493 32. Clinical Features - p. 493 33. Chronic Hepatitis Pattern of Injury - p. 496 34. Chronic Viral Hepatitis - p. 498 35. Autoimmune Hepatitis - p. 502 36. Fatty Liver Disease or Steatohepatitis Pattern of Injury - p. 505 37. Nonalcoholic Fatty Liver Disease - p. 505 38. Alcoholic Liver Disease - p. 509 39. Disorders of the Bile Ducts - p. 513 40. Large Duct Obstruction - p. 513 41. Primary Biliary Cholangitis - p. 516 42. Primary Sclerosing Cholangitis - p. 519 43. Laboratory Findings - p. 519 44. Overlap Syndromes (Autoimmune Hepatitis, Primary Biliary Cholangitis, And Primary Sclerosing Cholangitis) - p. 522 45. Vascular Pattern Of Injury - p. 522 46. Budd-Chiari Syndrome - p. 523 47. Clinical Features - p. 523 48. Congestive (Cardiac) Hepatopathy - p. 524 49. Clinical Features - p. 524 50. Sinusoidal Obstruction Syndrome - p. 525 51. Clinical Features - p. 525 52. Portal Vein Thrombosis or Obstruction - p. 526 53. Nodular Regenerative Hyperplasia - p. 527 54. Clinical Features - p. 527 55. Hepatoportal Sclerosis - p. 528 56. Clinical Features - p. 528 57. Peliosis Hepatis - p. 530 58. Clinical Features - p. 530 59. Drug-Induced Liver Injury - p. 530 60. Clinical Features - p. 531 61. Miscellaneous Patterns of Injury - p. 535 62. “Almost Normal” Biopsy or Nonspecific Findings - p. 535 63. Hepatic Granulomas - p. 537 64. Necrosis - p. 537 65. Metabolic Diseases - p. 538 66. Iron Overload - p. 538 67. Hereditary Hemochromatosis - p. 539 68. Clinical Features - p. 539 69. Secondary Iron Overload - p. 541 70. Copper Accumulation Disorder - p. 542 71. Clinical Features - p. 542 72. Clinical Features - p. 544 73. Glycogen Storage Diseases - p. 546 74. Clinical Features - p. 546 75. Clinical Features - p. 549 76. Glycogenic Hepatopathy - p. 552 77. Porphyrias - p. 553 78. Suggested Readings - p. 555 79. 18. Liver Neoplasms - p. 557 80. 19. Gastrointestinal Lymphoma - p. 613 81. 20. Pathology of Liver, Small Bowel, and Pancreas Transplantation - p. 657 82. Index - p. 691
Now fully revised to include recent advances in the field, the third edition of Gastrointestinal and Liver Pathology Pathology, a volume in the Foundations in Diagnostic Pathology series, is an essential foundation text for residents and pathologists. The popular template format makes it easy to use, and new information throughout brings you up to date with what’s new in the field, including advances in molecular diagnostic testing and new diagnostic biomarkers. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice.
Key features of this practical text include:
A consistent, user-friendly format that explores each entity's clinical features, gross and microscopic findings, ancillary studies, differential diagnoses, and prognostic and therapeutic considerations.
A focus on specific features of selected neoplastic and non-neoplastic entities, including broad and in-depth differential diagnoses.
Clinical information on treatment and prognosis, enabling you to better understand the clinical implications of the diagnosis.
Nearly 1,000 full-color, high-quality illustrations with extensive figure legends, as well as abundant boxes and tables throughout.
What’s NEW in this edition:
Advances in molecular diagnostic testing and its capabilities and limitations, including targeted/personalized medicine.
New diagnostic biomarkers and their utility in differential diagnosis, newly described variants, and new histologic entities.
The latest TNM staging and WHO classification systems.
New co-editors Drs. Amitabh Srivastava and Daniela S. Allende lead a team of expert, internationally recognized pathologists who keep you up to date with the latest information in the field.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. iv 6. Contributors - p. vii 7. Foreword - p. ix 8. Preface - p. ix 9. Acknowledgments - p. xiii 10. 1. Non-Neoplastic Disorders of the Esophagus - p. 1 11. 2. Tumors of the Esophagus - p. 29 12. 3. Non-Neoplastic Disorders of the Stomach - p. 53 13. 4. Epithelial Polyps and Neoplasms of the Stomach - p. 91 14. 5. Non-Neoplastic and Inflammatory Disorders of the Small Bowel - p. 119 15. 6. Neoplasms of the Small Intestine - p. 151 16. 7. Gastrointestinal Mesenchymal Tumors - p. 169 17. 8. Non-Neoplastic and Neoplastic Disorders of the Appendix - p. 211 18. 9. Infectious Diseases of the Gastrointestinal Tract - p. 243 19. 10. Non-neoplastic Disorders of the Colon - p. 299 20. 11. Gastrointestinal Polyposis Syndromes - p. 337 21. 12. Epithelial Neoplasms of the Colorectum - p. 363 22. 13. Molecular Testing of Gastrointestinal Neoplasms - p. 395 23. 14. Pathology of the Anal Canal - p. 407 24. 15. Pathology of the Gallbladder and Extrahepatic Bile Ducts - p. 436 25. 16. Non-Neoplastic and Neoplastic Pathology of the Pancreas - p. 455 26. 17. Non-Neoplastic Disorders of the Liver - p. 489 27. Major Histologic Patterns of Injury - p. 489 28. Acute Hepatitis Pattern of Injury - p. 489 29. Acute Viral (Hepatotropic) Hepatitis - p. 491 30. Clinical Features - p. 491 31. Nonhepatotropic Viral Infections - p. 493 32. Clinical Features - p. 493 33. Chronic Hepatitis Pattern of Injury - p. 496 34. Chronic Viral Hepatitis - p. 498 35. Autoimmune Hepatitis - p. 502 36. Fatty Liver Disease or Steatohepatitis Pattern of Injury - p. 505 37. Nonalcoholic Fatty Liver Disease - p. 505 38. Alcoholic Liver Disease - p. 509 39. Disorders of the Bile Ducts - p. 513 40. Large Duct Obstruction - p. 513 41. Primary Biliary Cholangitis - p. 516 42. Primary Sclerosing Cholangitis - p. 519 43. Laboratory Findings - p. 519 44. Overlap Syndromes (Autoimmune Hepatitis, Primary Biliary Cholangitis, And Primary Sclerosing Cholangitis) - p. 522 45. Vascular Pattern Of Injury - p. 522 46. Budd-Chiari Syndrome - p. 523 47. Clinical Features - p. 523 48. Congestive (Cardiac) Hepatopathy - p. 524 49. Clinical Features - p. 524 50. Sinusoidal Obstruction Syndrome - p. 525 51. Clinical Features - p. 525 52. Portal Vein Thrombosis or Obstruction - p. 526 53. Nodular Regenerative Hyperplasia - p. 527 54. Clinical Features - p. 527 55. Hepatoportal Sclerosis - p. 528 56. Clinical Features - p. 528 57. Peliosis Hepatis - p. 530 58. Clinical Features - p. 530 59. Drug-Induced Liver Injury - p. 530 60. Clinical Features - p. 531 61. Miscellaneous Patterns of Injury - p. 535 62. “Almost Normal” Biopsy or Nonspecific Findings - p. 535 63. Hepatic Granulomas - p. 537 64. Necrosis - p. 537 65. Metabolic Diseases - p. 538 66. Iron Overload - p. 538 67. Hereditary Hemochromatosis - p. 539 68. Clinical Features - p. 539 69. Secondary Iron Overload - p. 541 70. Copper Accumulation Disorder - p. 542 71. Clinical Features - p. 542 72. Clinical Features - p. 544 73. Glycogen Storage Diseases - p. 546 74. Clinical Features - p. 546 75. Clinical Features - p. 549 76. Glycogenic Hepatopathy - p. 552 77. Porphyrias - p. 553 78. Suggested Readings - p. 555 79. 18. Liver Neoplasms - p. 557 80. 19. Gastrointestinal Lymphoma - p. 613 81. 20. Pathology of Liver, Small Bowel, and Pancreas Transplantation - p. 657 82. Index - p. 691