This issue describes in detail the most current thinking on the way genes affect and determine sleep patterns, behaviors, disorders and needs. Sleep researchers continue to study genetic markers that may someday lead to a personalized approach to treatment of sleep disorders. The genetics of restless legs syndrome, narcolepsy, circadian rhythm disorders, obstructive sleep apnea, parasomnias, and insomnia are discussed. A solid understanding of the role genetics and molecular biology play in sleep will aid clinicians in diagnosing and treating these disorders, as well as advising their patients.
1. Cover - p. 1 2. CME Accreditation Page and Author Disclosure - p. 2 3. Forthcoming Issues - p. 3 4. Contributors - p. 4 5. Contents - p. 5 6. Foreword - p. 6 7. Genetics of Sleep and Its Disorders - p. 7 8. Non-mammalian Genetic Model Systems in Sleep Research - p. 8 9. The Genetics of Sleep: Insight from Rodent Models - p. 14 10. Genetics of Electroencephalography During Wakefulness and Sleep - p. 24 11. Genetics of Sleep Timing, Duration, and Homeostasis in Humans - p. 34 12. Genetics of Circadian Rhythm Disorders - p. 43 13. Genetics of Insomnia - p. 49 14. Genetics of Restless Legs Syndrome: Mendelian, Complex, and Everything in Between - p. 59 15. Genetics of Narcolepsy - p. 70 16. Genetics of Parasomnias - p. 80 17. Genetics of Sleep Apnea - p. 87 18. Genetics of Cardiovascular Consequences of Obstructive Sleep Apnea Syndrome - p. 95 19. Index - p. 102
This issue describes in detail the most current thinking on the way genes affect and determine sleep patterns, behaviors, disorders and needs. Sleep researchers continue to study genetic markers that may someday lead to a personalized approach to treatment of sleep disorders. The genetics of restless legs syndrome, narcolepsy, circadian rhythm disorders, obstructive sleep apnea, parasomnias, and insomnia are discussed. A solid understanding of the role genetics and molecular biology play in sleep will aid clinicians in diagnosing and treating these disorders, as well as advising their patients.
1. Cover - p. 1 2. CME Accreditation Page and Author Disclosure - p. 2 3. Forthcoming Issues - p. 3 4. Contributors - p. 4 5. Contents - p. 5 6. Foreword - p. 6 7. Genetics of Sleep and Its Disorders - p. 7 8. Non-mammalian Genetic Model Systems in Sleep Research - p. 8 9. The Genetics of Sleep: Insight from Rodent Models - p. 14 10. Genetics of Electroencephalography During Wakefulness and Sleep - p. 24 11. Genetics of Sleep Timing, Duration, and Homeostasis in Humans - p. 34 12. Genetics of Circadian Rhythm Disorders - p. 43 13. Genetics of Insomnia - p. 49 14. Genetics of Restless Legs Syndrome: Mendelian, Complex, and Everything in Between - p. 59 15. Genetics of Narcolepsy - p. 70 16. Genetics of Parasomnias - p. 80 17. Genetics of Sleep Apnea - p. 87 18. Genetics of Cardiovascular Consequences of Obstructive Sleep Apnea Syndrome - p. 95 19. Index - p. 102
