Clinically focused and designed to provide a to-the-point overview, Glioblastoma , by Drs. Steven Brem and Kalil G. Abdullah, brings you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides neurosurgeons, medical-and-radiation oncologists, neuro-oncologists, neuropathologists, internal medicine physicians, and researchers with a dependable source of information on current treatment options, tumor recurrence, and patient care.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Glioblastoma: Translating Scientific Advances to Innovative Therapy - p. viii 7. List of Tables - p. x 8. Part I: Disease Origins and Context - p. x 9. Chapter 1: The Story of Glioblastoma: History and Modern Correlates - p. x 10. Chapter 2: Epidemiology of Glioblastoma and Trends in Glioblastoma Survivorship - p. 7 11. Chapter 3: The Molecular Pathogenesis of Glioblastoma - p. 18 12. Chapter 4: Translating Molecular Biomarkers of Gliomas to Clinical Practice - p. 30 13. Chapter 5: Multimodality Targeting of Glioma Cells - p. 49 14. Part II: Standards of Medical and Surgical Treatment - p. 65 15. Chapter 6: Current Standards of Care in Glioblastoma Therapy - p. 65 16. Chapter 7: Radiographic Detection and Advanced Imaging of Glioblastoma - p. 79 17. Chapter 8: Principles and Tenets of Radiation Treatment in Glioblastoma - p. 100 18. Chapter 9: Chemotherapeutics and Their Efficacy - p. 127 19. Chapter 10: Antiangiogenic Therapy for Glioblastoma - p. 139 20. Chapter 11: Recurrent Glioblastoma - p. 148 21. Chapter 12: Principles of Surgical Treatment - p. 162 22. Chapter 13: Awake Craniotomy for Glioblastoma - p. 172 23. Chapter 14: Intraoperative Imaging of Glioblastoma - p. 183 24. Chapter 15: Minimally Invasive Targeted Therapy for Glioblastoma: Laser Interstitial Thermal Therapy - p. 193 25. Chapter 16: Local Drug Delivery in the Treatment of Glioblastoma - p. 202 26. Chapter 17: Tumor-Treating Electric Fields for Glioblastoma - p. 211 27. Part III: Scientific advances, future directions, and socioeconomic considerations - p. 222 28. Chapter 18: Brain Plasticity and Reorganization Before, During, and After Glioma Resection - p. 222 29. Chapter 19: General Principles of Immunotherapy for Glioblastoma - p. 233 30. Chapter 20: Early Detection of Glioblastoma - p. 244 31. Chapter 21: Health-related Quality of Life and Neurocognitive Functioning After Glioblastoma Treatment - p. 250 32. Chapter 22: Socioeconomics and Survival - p. 259 33. Chapter 23: National and Global Economic Impact of Glioblastoma - p. 268 34. Chapter 24: Lessons Learned: Clinical Trials and Other Interventions for Glioblastoma - p. 277 35. Index - p. 285
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Clinically focused and designed to provide a to-the-point overview, Glioblastoma , by Drs. Steven Brem and Kalil G. Abdullah, brings you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides neurosurgeons, medical-and-radiation oncologists, neuro-oncologists, neuropathologists, internal medicine physicians, and researchers with a dependable source of information on current treatment options, tumor recurrence, and patient care.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Glioblastoma: Translating Scientific Advances to Innovative Therapy - p. viii 7. List of Tables - p. x 8. Part I: Disease Origins and Context - p. x 9. Chapter 1: The Story of Glioblastoma: History and Modern Correlates - p. x 10. Chapter 2: Epidemiology of Glioblastoma and Trends in Glioblastoma Survivorship - p. 7 11. Chapter 3: The Molecular Pathogenesis of Glioblastoma - p. 18 12. Chapter 4: Translating Molecular Biomarkers of Gliomas to Clinical Practice - p. 30 13. Chapter 5: Multimodality Targeting of Glioma Cells - p. 49 14. Part II: Standards of Medical and Surgical Treatment - p. 65 15. Chapter 6: Current Standards of Care in Glioblastoma Therapy - p. 65 16. Chapter 7: Radiographic Detection and Advanced Imaging of Glioblastoma - p. 79 17. Chapter 8: Principles and Tenets of Radiation Treatment in Glioblastoma - p. 100 18. Chapter 9: Chemotherapeutics and Their Efficacy - p. 127 19. Chapter 10: Antiangiogenic Therapy for Glioblastoma - p. 139 20. Chapter 11: Recurrent Glioblastoma - p. 148 21. Chapter 12: Principles of Surgical Treatment - p. 162 22. Chapter 13: Awake Craniotomy for Glioblastoma - p. 172 23. Chapter 14: Intraoperative Imaging of Glioblastoma - p. 183 24. Chapter 15: Minimally Invasive Targeted Therapy for Glioblastoma: Laser Interstitial Thermal Therapy - p. 193 25. Chapter 16: Local Drug Delivery in the Treatment of Glioblastoma - p. 202 26. Chapter 17: Tumor-Treating Electric Fields for Glioblastoma - p. 211 27. Part III: Scientific advances, future directions, and socioeconomic considerations - p. 222 28. Chapter 18: Brain Plasticity and Reorganization Before, During, and After Glioma Resection - p. 222 29. Chapter 19: General Principles of Immunotherapy for Glioblastoma - p. 233 30. Chapter 20: Early Detection of Glioblastoma - p. 244 31. Chapter 21: Health-related Quality of Life and Neurocognitive Functioning After Glioblastoma Treatment - p. 250 32. Chapter 22: Socioeconomics and Survival - p. 259 33. Chapter 23: National and Global Economic Impact of Glioblastoma - p. 268 34. Chapter 24: Lessons Learned: Clinical Trials and Other Interventions for Glioblastoma - p. 277 35. Index - p. 285
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