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Granulomatous disorders represent a unique group of diseases both non-infectious and infectious that require the utmost clinical pathologic correlation combined with a keen sense of inquiry for underlying systemic disease. Some of these diseases are common and some are rare; however all dermatologists need to diagnose and manage these diseases whether common or rare. This issue of Dermatology Clinics "Granulomatous Disorders of the Adult Skin" supplies the readers with a comprehensive, up to date, and evidence based review of multiple granulomatous disorders (i.e. palisdaing, epitheliod, xanthomatous, casseating, supprative, vasculitic, lymphoproliferative, foreign body). Dermatologists need to be able to differentiate the entities, evaluate patients for specific underlying systemic diseases (diabetes to cancer) and treat with a wide range of immunosuppressant to anti-infectious agents. This issue will help the dermatologist learn the most current etiopathogenesis, clinical/systemic manifestations and therapeutic modalities for these diseases. Other specialists who would find the information useful: Rheumatologists, Infectious Disease specialists, Hematologists/Oncologists, Endocrinologists, Pulmonologists, Oral-maxillary surgeons, and Pharmacists.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 9 7. Preface: Granulomatous Disorders of the Adult Skin: Twenty-First Century - p. 10 8. Granuloma Annulare - p. 11 9. Elastolytic Actinic Giant Cell Granuloma - p. 21 10. Necrobiosis Lipoidica - p. 28 11. Rheumatoid Nodules - p. 39 12. Reactive Granulomatous Dermatitis - p. 47 13. Sarcoidosis - p. 56 14. Cutaneous Manifestations of Crohn Disease - p. 74 15. Orofacial Granulomatosis - p. 86 16. Granulomatous Rosacea and Periorificial Dermatitis - p. 94 17. Adult Orbital Xanthogranulomatous Disease - p. 101 18. Adult Xanthogranuloma, Reticulohistiocytosis, and Rosai-Dorfman Disease - p. 106 19. Granulomatous Vasculitis - p. 112 20. Granulomatous Lymphoproliferative Disorders - p. 121 21. Foreign Body Granulomas - p. 126 22. Granulomatous Drug Eruptions - p. 142 23. Tuberculosis and Leprosy - p. 152 24. Nontuberculous Mycobacteria - p. 165 25. New World and Old World Leishmania Infections - p. 176 26. Deep Fungal Infections, Blastomycosis-Like Pyoderma, and Granulomatous Sexually Transmitted Infections - p. 184 27. Clinical Atlas of Granulomatous Disorders - p. 192 28. Index - p. 194

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Granulomatous disorders represent a unique group of diseases both non-infectious and infectious that require the utmost clinical pathologic correlation combined with a keen sense of inquiry for underlying systemic disease. Some of these diseases are common and some are rare; however all dermatologists need to diagnose and manage these diseases whether common or rare. This issue of Dermatology Clinics "Granulomatous Disorders of the Adult Skin" supplies the readers with a comprehensive, up to date, and evidence based review of multiple granulomatous disorders (i.e. palisdaing, epitheliod, xanthomatous, casseating, supprative, vasculitic, lymphoproliferative, foreign body). Dermatologists need to be able to differentiate the entities, evaluate patients for specific underlying systemic diseases (diabetes to cancer) and treat with a wide range of immunosuppressant to anti-infectious agents. This issue will help the dermatologist learn the most current etiopathogenesis, clinical/systemic manifestations and therapeutic modalities for these diseases. Other specialists who would find the information useful: Rheumatologists, Infectious Disease specialists, Hematologists/Oncologists, Endocrinologists, Pulmonologists, Oral-maxillary surgeons, and Pharmacists.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 9 7. Preface: Granulomatous Disorders of the Adult Skin: Twenty-First Century - p. 10 8. Granuloma Annulare - p. 11 9. Elastolytic Actinic Giant Cell Granuloma - p. 21 10. Necrobiosis Lipoidica - p. 28 11. Rheumatoid Nodules - p. 39 12. Reactive Granulomatous Dermatitis - p. 47 13. Sarcoidosis - p. 56 14. Cutaneous Manifestations of Crohn Disease - p. 74 15. Orofacial Granulomatosis - p. 86 16. Granulomatous Rosacea and Periorificial Dermatitis - p. 94 17. Adult Orbital Xanthogranulomatous Disease - p. 101 18. Adult Xanthogranuloma, Reticulohistiocytosis, and Rosai-Dorfman Disease - p. 106 19. Granulomatous Vasculitis - p. 112 20. Granulomatous Lymphoproliferative Disorders - p. 121 21. Foreign Body Granulomas - p. 126 22. Granulomatous Drug Eruptions - p. 142 23. Tuberculosis and Leprosy - p. 152 24. Nontuberculous Mycobacteria - p. 165 25. New World and Old World Leishmania Infections - p. 176 26. Deep Fungal Infections, Blastomycosis-Like Pyoderma, and Granulomatous Sexually Transmitted Infections - p. 184 27. Clinical Atlas of Granulomatous Disorders - p. 192 28. Index - p. 194

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