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This issue of the Surgical Pathology Clinics, edited by Drs. Blaise Clarke and Glenn McCluggage, focuses on Gynecologic Pathology. Topics covered in the issue include, but are not limited to: Gynecologic manifestations of the DICER1 syndrome; Prophylactic gynecologic specimens from hereditary cancer carriers; Lynch syndrome associated endometrial cancer; Peutz-jeghers syndrome associated gynecologic tumors; Gynecologic manifestations of less commonly encountered hereditary syndromes; and Clinical testing for hereditary predisposition.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 6 7. Preface: Gynecologic Pathology - p. 7 8. Ovarian Cancer in Hereditary Cancer Susceptibility Syndromes - p. 8 9. Lynch Syndrome - p. 16 10. Small-Cell Carcinoma of the Ovary of Hypercalcemic Type (Malignant Rhabdoid Tumor of the Ovary) - p. 24 11. Gynecologic Manifestations of the DICER1 Syndrome - p. 32 12. Peutz-Jeghers Syndrome - p. 40 13. Gynecologic Manifestations of Less Commonly Encountered Hereditary Syndromes - p. 55 14. Laboratory Assays in Evaluation of Lynch Syndrome in Patients with Endometrial Carcinoma - p. 63 15. Testing for Hereditary Predisposition in Patients with Gynecologic Cancers, Quo Vadis? - p. 71 16. Prophylactic Gynecologic Specimens from Hereditary Cancer Carriers - p. 76 17. Special article - p. 86 18. Image Analysis in Surgical Pathology - p. 87

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This issue of the Surgical Pathology Clinics, edited by Drs. Blaise Clarke and Glenn McCluggage, focuses on Gynecologic Pathology. Topics covered in the issue include, but are not limited to: Gynecologic manifestations of the DICER1 syndrome; Prophylactic gynecologic specimens from hereditary cancer carriers; Lynch syndrome associated endometrial cancer; Peutz-jeghers syndrome associated gynecologic tumors; Gynecologic manifestations of less commonly encountered hereditary syndromes; and Clinical testing for hereditary predisposition.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. Forthcoming Issues - p. 6 7. Preface: Gynecologic Pathology - p. 7 8. Ovarian Cancer in Hereditary Cancer Susceptibility Syndromes - p. 8 9. Lynch Syndrome - p. 16 10. Small-Cell Carcinoma of the Ovary of Hypercalcemic Type (Malignant Rhabdoid Tumor of the Ovary) - p. 24 11. Gynecologic Manifestations of the DICER1 Syndrome - p. 32 12. Peutz-Jeghers Syndrome - p. 40 13. Gynecologic Manifestations of Less Commonly Encountered Hereditary Syndromes - p. 55 14. Laboratory Assays in Evaluation of Lynch Syndrome in Patients with Endometrial Carcinoma - p. 63 15. Testing for Hereditary Predisposition in Patients with Gynecologic Cancers, Quo Vadis? - p. 71 16. Prophylactic Gynecologic Specimens from Hereditary Cancer Carriers - p. 76 17. Special article - p. 86 18. Image Analysis in Surgical Pathology - p. 87

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